HBV Target gene Detail Information

> RXRA Gene Search Result

Gene Information

Gene Name	RXRA
Gene ID	6256
Gene Full Name	retinoid X receptor alpha
Gene Alias	NR2B1
Transcripts	ENSG00000186350
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Golgi apparatus;
HPA Protein Class Info	Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors
Uniport_ID	P19793
HGNC ID	HGNC:10477
VEGA ID	OTTHUMG00000020887
OMIM ID	180245
String ID	9606.ENSP00000419692
Drugbank ID	BE0000412
Drug (Cytoscape Annotation)	Bexarotene
PharmGKB ID	PA34890

Target gene [RXRA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003600	chr9	21	10	91	122	View
1005126	chr9	55	6		61	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of RXRA expression and immune infiltrating cell level correlation result in HBV+ samples
RXRA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).