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HBV Target gene Detail Information

> S100A9 Gene Search Result


Gene Information
Gene Name S100A9
Gene ID 6280
Gene Full Name S100 calcium binding protein A9
Gene Alias MIF; NIF; P14; CAGB; CFAG; CGLB; L1AG; LIAG; MRP14; 60B8AG; MAC387
Transcripts ENSG00000163220
Virus HBV
Gene Type protein coding
HPA Location Info Cell Junctions;Cytosol;Nucleoplasm;Predicted to be secreted;
HPA Protein Class Info Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P06702
HGNC ID HGNC:10499
VEGA ID OTTHUMG00000013125
OMIM ID 123886
String ID 9606.ENSP00000357727
Drugbank ID BE0008918
PharmGKB ID PA34911
Target gene [S100A9] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002375 chr1 192 58 34 284 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of S100A9 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
S100A9 expression: Low -> High
Lollipop of S100A9 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of S100A9 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of S100A9 expression and immune infiltrating cell level correlation result in HBV+ samples
S100A9 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).