HBV Target gene Detail Information

> SENP5 Gene Search Result

Gene Information

Gene Name	SENP5
Gene ID	205564
Gene Full Name	SUMO specific peptidase 5
Transcripts	ENSG00000119231
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoplasm;Centrosome;Cytosol;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q96HI0
HGNC ID	HGNC:28407
VEGA ID	OTTHUMG00000155527
OMIM ID	612845
String ID	9606.ENSP00000327197
PharmGKB ID	PA134917083

Target gene [SENP5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001843	chr3	301	155	3	459	View
1001922	chr3	263	153	3	419	View
1001995	chr3	235	145	3	383	View
1002032	chr3	223	144	2	369	View
1002050	chr3	219	143		362	View
1002103	chr3	278	64	3	345	View
1002114	chr3	278	60	3	341	View
1002119	chr3	203	135		338	View
1002182	chr3	270	48	3	321	View
1002662	chr3	153	74		227	View
1008785	chr3	12	7		19	View
1400230	chr3	217	143		360	View
1400242	chr3	221	143	1	365	View
1400246	chr3	141	46		187	View
1401202	chr3	219	143		362	View
1401526	chr3	153	74		227	View
1401838	chr3	278	64	3	345	View
1403960	chr3	203	135		338	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE114783 (GEO)	Chronic HBV (CHB) infection	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO)	Hepatocellular carcinoma	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO)	Liver cirrhosis	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783
HeatMap of cell type fractions in all samples	Lollipop of SENP5 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
SENP5 expression: Low -> High
Lollipop of SENP5 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples	Lollipop of SENP5 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples


> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SENP5 expression and immune infiltrating cell level correlation result in HBV+ samples
SENP5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).