HIV Target gene Detail Information

> SETBP1 Gene Search Result

Gene Information

Gene Name	SETBP1
Gene ID	26040
Gene Full Name	SET binding protein 1
Gene Alias	SEB; MRD29
Transcripts	ENSG00000152217
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;Nuclear bodies;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q9Y6X0
HGNC ID	HGNC:15573
VEGA ID	OTTHUMG00000132613
OMIM ID	611060
String ID	9606.ENSP00000282030
PharmGKB ID	PA37982

Target gene [SETBP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005147	chr18	12	23		35	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SETBP1 expression and immune infiltrating cell level correlation result in HIV+ samples
SETBP1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SETBP1 expression and immune infiltrating cell level correlation result in HIV+ samples
SETBP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).