HBV Target gene Detail Information

> SIN3A Gene Search Result

Gene Information

Gene Name	SIN3A
Gene ID	25942
Gene Full Name	SIN3 transcription regulator family member A
Gene Alias	WITKOS
Transcripts	ENSG00000169375
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q96ST3
HGNC ID	HGNC:19353
VEGA ID	OTTHUMG00000142834
OMIM ID	607776
String ID	9606.ENSP00000378402
PharmGKB ID	PA134993567

Target gene [SIN3A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005437	chr15	53	1		54	View
1005438	chr15	53	1		54	View
1010696	chr15	7	4		11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SIN3A expression and immune infiltrating cell level correlation result in HBV+ samples
SIN3A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).