HBV Target gene Detail Information

> SLC12A7 Gene Search Result

Gene Information

Gene Name	SLC12A7
Gene ID	10723
Gene Full Name	solute carrier family 12 member 7
Gene Alias	KCC4
Transcripts	ENSG00000276482
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q9Y666
HGNC ID	HGNC:10915
VEGA ID	OTTHUMG00000190154
OMIM ID	604879
String ID	9606.ENSP00000264930
Drugbank ID	BE0000276
PharmGKB ID	PA35809

Target gene [SLC12A7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009692	chr5	10	4	1	15	View
1010602	chr5	11			11	View
1010927	chr5	10			10	View
1402381	chr5	10			10	View
1403112	chr5	11			11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SLC12A7 expression and immune infiltrating cell level correlation result in HBV+ samples
SLC12A7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).