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HTLV1 Target gene Detail Information

> SLC16A5 Gene Search Result


Gene Information
Gene Name SLC16A5
Gene ID 9121
Gene Full Name solute carrier family 16 member 5
Gene Alias MCT5; MCT6
Transcripts ENSG00000170190
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins, Transporters
Uniport_ID O15375
HGNC ID HGNC:10926
VEGA ID OTTHUMG00000179277
OMIM ID 603879
String ID 9606.ENSP00000390564
Drugbank ID BE0000386
PharmGKB ID PA35817
Target gene [SLC16A5] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6007049 chr17 12 13 35 60 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of SLC16A5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC16A5 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of SLC16A5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC16A5 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of SLC16A5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC16A5 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).