HTLV1 Target gene Detail Information

> SLC35C1 Gene Search Result

Gene Information

Gene Name	SLC35C1
Gene ID	55343
Gene Full Name	solute carrier family 35 member C1
Gene Alias	CDG2C; FUCT1
Transcripts	ENSG00000181830
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID	Q96A29
HGNC ID	HGNC:20197
VEGA ID	OTTHUMG00000166519
OMIM ID	605881
String ID	9606.ENSP00000313318
PharmGKB ID	PA134930330

Target gene [SLC35C1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000184	chr11	2817	173	259	3249	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of SLC35C1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC35C1 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of SLC35C1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC35C1 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of SLC35C1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC35C1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).