HTLV1 Target gene Detail Information

> SLC35F4 Gene Search Result


Gene Information
Gene Name SLC35F4
Gene ID 341880
Gene Full Name solute carrier family 35 member F4
Gene Alias C14orf36; c14_5373
Transcripts ENSG00000151812
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoli fibrillar center;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins, Transporters
Uniport_ID A4IF30
HGNC ID HGNC:19845
VEGA ID OTTHUMG00000171317
String ID 9606.ENSP00000342518
PharmGKB ID PA134959551
Target gene [SLC35F4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6010185 chr14 8 21 3 32 View
6011029 chr14 17 11 28 View
6012895 chr14 9 5 7 21 View
6012896 chr14 9 5 7 21 View
6022981 chr14 2 2 4 View
6025084 chr14 2 1 3 View
6027384 chr14 2 2 View
6028509 chr14 1 1 View
6031667 chr14 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of SLC35F4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC35F4 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of SLC35F4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC35F4 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of SLC35F4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC35F4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).