HTLV1 Target gene Detail Information

> SLC37A4 Gene Search Result


Gene Information
Gene Name SLC37A4
Gene ID 2542
Gene Full Name solute carrier family 37 member 4
Gene Alias G6PT1; G6PT2; G6PT3; GSD1b; GSD1c; GSD1d; TRG19; TRG-19; PRO0685
Transcripts ENSG00000281500
Virus HTLV1
Gene Type protein coding
HPA Location Info Mitochondria;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins
HGNC ID HGNC:4061
VEGA ID OTTHUMG00000166352
OMIM ID 602671
String ID 9606.ENSP00000476176
PharmGKB ID PA28472
Target gene [SLC37A4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6010044 chr11 14 10 9 33 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of SLC37A4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC37A4 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of SLC37A4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC37A4 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of SLC37A4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC37A4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).