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HTLV1 Target gene Detail Information

> SLC6A5 Gene Search Result


Gene Information
Gene Name SLC6A5
Gene ID 9152
Gene Full Name solute carrier family 6 member 5
Gene Alias NET1; GLYT2; HKPX3; GLYT-2
Transcripts ENSG00000165970
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID Q9Y345
HGNC ID HGNC:11051
VEGA ID OTTHUMG00000166024
OMIM ID 604159
String ID 9606.ENSP00000434364
Drugbank ID BE0002310
PharmGKB ID PA35911
Target gene [SLC6A5] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6019815 chr11 5 2 7 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of SLC6A5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC6A5 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of SLC6A5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC6A5 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of SLC6A5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC6A5 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).