HTLV1 Target gene Detail Information

> SLCO2B1 Gene Search Result

Gene Information

Gene Name	SLCO2B1
Gene ID	11309
Gene Full Name	solute carrier organic anion transporter family member 2B1
Gene Alias	OATPB; OATP-B; OATP2B1; SLC21A9
Transcripts	ENSG00000137491
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	O94956
HGNC ID	HGNC:10962
VEGA ID	OTTHUMG00000165420
OMIM ID	604988
String ID	9606.ENSP00000289575
Drugbank ID	BE0001042
PharmGKB ID	PA35845

Target gene [SLCO2B1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000865	chr11	126	241	398	765	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of SLCO2B1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLCO2B1 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of SLCO2B1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLCO2B1 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of SLCO2B1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLCO2B1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).