HBV Target gene Detail Information

> SMAD1 Gene Search Result

Gene Information

Gene Name	SMAD1
Gene ID	4086
Gene Full Name	SMAD family member 1
Gene Alias	BSP1; JV41; BSP-1; JV4-1; MADH1; MADR1
Transcripts	ENSG00000170365
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q15797
HGNC ID	HGNC:6767
VEGA ID	OTTHUMG00000161592
OMIM ID	601595
String ID	9606.ENSP00000426568
PharmGKB ID	PA30524

Target gene [SMAD1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010506	chr4	8	3	1	12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SMAD1 expression and immune infiltrating cell level correlation result in HBV+ samples
SMAD1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).