HBV Target gene Detail Information

> SRD5A2 Gene Search Result

Gene Information

Gene Name	SRD5A2
Gene ID	6716
Gene Full Name	steroid 5 alpha-reductase 2
Transcripts	ENSG00000277893
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins
Uniport_ID	P31213
HGNC ID	HGNC:11285
VEGA ID	OTTHUMG00000152057
OMIM ID	607306
String ID	9606.ENSP00000477587
Drugbank ID	BE0000585; BE0004887
PharmGKB ID	PA36113

Target gene [SRD5A2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000747	chr2	26	719	779	1524	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SRD5A2 expression and immune infiltrating cell level correlation result in HBV+ samples
SRD5A2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).