HTLV1 Target gene Detail Information

> STAB1 Gene Search Result

Gene Information

Gene Name	STAB1
Gene ID	23166
Gene Full Name	stabilin 1
Gene Alias	FEX1; FEEL-1; FELE-1; SCARH2; STAB-1; CLEVER-1
Transcripts	ENSG00000010327
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q9NY15
HGNC ID	HGNC:18628
VEGA ID	OTTHUMG00000158574
OMIM ID	608560
String ID	9606.ENSP00000312946
PharmGKB ID	PA38610

Target gene [STAB1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6001408	chr3	381	54	13	448	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of STAB1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
STAB1 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of STAB1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
STAB1 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of STAB1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
STAB1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).