HIV Target gene Detail Information

> STIM1 Gene Search Result

Gene Information

Gene Name	STIM1
Gene ID	6786
Gene Full Name	stromal interaction molecule 1
Gene Alias	GOK; TAM; TAM1; IMD10; STRMK; D11S4896E
Transcripts	ENSG00000167323
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q13586
HGNC ID	HGNC:11386
VEGA ID	OTTHUMG00000133360
OMIM ID	605921
String ID	9606.ENSP00000478059
PharmGKB ID	PA36195

Target gene [STIM1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000888	chr11	58	135	62	255	View
4000894	chr11	58	135	62	255	View
4000906	chr11	56	134	62	252	View
4002690	chr11	10	63	11	84	View
4003066	chr11	3	52	15	70	View
4003709	chr11	15	22	19	56	View
4006480	chr11	19	5		24	View
4011176	chr11	7			7	View
4011556	chr11	3	3		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of STIM1 expression and immune infiltrating cell level correlation result in HIV+ samples
STIM1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of STIM1 expression and immune infiltrating cell level correlation result in HIV+ samples
STIM1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).