HBV Target gene Detail Information

> SYT1 Gene Search Result

Gene Information

Gene Name	SYT1
Gene ID	6857
Gene Full Name	synaptotagmin 1
Gene Alias	P65; SYT; SVP65
Transcripts	ENSG00000067715
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Gene Function	Oncogene
Uniport_ID	P21579
HGNC ID	HGNC:11509
VEGA ID	OTTHUMG00000134326
OMIM ID	185605
String ID	9606.ENSP00000261205
PharmGKB ID	PA36290

Target gene [SYT1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1018121	chr12				0	View
1018122	chr12				0	View
1019404	chr12				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SYT1 expression and immune infiltrating cell level correlation result in HBV+ samples
SYT1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).