HIV Target gene Detail Information

> TARDBP Gene Search Result

Gene Information

Gene Name	TARDBP
Gene ID	23435
Gene Full Name	TAR DNA binding protein
Gene Alias	ALS10; TDP-43
Transcripts	ENSG00000120948
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q13148
HGNC ID	HGNC:11571
VEGA ID	OTTHUMG00000002120
OMIM ID	605078
String ID	9606.ENSP00000240185
PharmGKB ID	PA36336

Target gene [TARDBP] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004651	chr1	25	16		41	View
4009431	chr1	11			11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TARDBP expression and immune infiltrating cell level correlation result in HIV+ samples
TARDBP expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TARDBP expression and immune infiltrating cell level correlation result in HIV+ samples
TARDBP expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).