HIV Target gene Detail Information

> TECR Gene Search Result

Gene Information

Gene Name	TECR
Gene ID	9524
Gene Full Name	trans-2,3-enoyl-CoA reductase
Gene Alias	SC2; TER; GPSN2; MRT14
Transcripts	ENSG00000099797
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins
Uniport_ID	Q9NZ01
HGNC ID	HGNC:4551
VEGA ID	OTTHUMG00000183290
OMIM ID	610057
String ID	9606.ENSP00000215567
PharmGKB ID	PA28946

Target gene [TECR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000015	chr19	2695	124	30	2849	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TECR expression and immune infiltrating cell level correlation result in HIV+ samples
TECR expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TECR expression and immune infiltrating cell level correlation result in HIV+ samples
TECR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).