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EBV Target gene Detail Information

> TMEM120B Gene Search Result


Gene Information
Gene Name TMEM120B
Gene ID 144404
Gene Full Name transmembrane protein 120B
Transcripts ENSG00000188735
Virus EBV
Gene Type protein coding
HPA Location Info Nucleoli fibrillar center;Cytosol;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID A0PK00
HGNC ID HGNC:32008
VEGA ID OTTHUMG00000169076
OMIM ID 616551
String ID 9606.ENSP00000404991
PharmGKB ID PA162405862
Target gene [TMEM120B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
3000296 chr12 15 23 38 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE102203 (GEO) B-cell lymphoma 9 Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE100458 (GEO) Burkitt lymphoma 14 Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO) Burkitt lymphoma 12 Burkitt lymphoma cell line Awia (EBV+)(12)
GSE45919 (GEO) Infectious mononucleosis 24 Infectious mononucleosis (IM)(EBV+)(3), Normal (9), Latent EBV (12)
GSE85599 (GEO) Infectious mononucleosis 17 Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE58240 (GEO) Multiple sclerosis 32 Multiple sclerosis IFN-β treated (EBV+)(16), Multiple sclerosis untreated (EBV+)(16)
GSE12452 (GEO) Nasopharyngeal carcinoma 41 Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE102203

HeatMap of cell type fractions in all samples Lollipop of TMEM120B expression and immune infiltrating cell level correlation result in EBV+ samples
TMEM120B expression: Low -> High

> Dataset: GSE100458

HeatMap of cell type fractions in all samples Lollipop of TMEM120B expression and immune infiltrating cell level correlation result in EBV+ samples
TMEM120B expression: Low -> High

> Dataset: GSE42867

HeatMap of cell type fractions in all samples Lollipop of TMEM120B expression and immune infiltrating cell level correlation result in EBV+ samples
TMEM120B expression: Low -> High

> Dataset: GSE45919

HeatMap of cell type fractions in all samples Lollipop of TMEM120B expression and immune infiltrating cell level correlation result in EBV+ samples
TMEM120B expression: Low -> High

> Dataset: GSE85599

HeatMap of cell type fractions in all samples Lollipop of TMEM120B expression and immune infiltrating cell level correlation result in EBV+ samples
TMEM120B expression: Low -> High

> Dataset: GSE58240

HeatMap of cell type fractions in all samples Lollipop of TMEM120B expression and immune infiltrating cell level correlation result in EBV+ samples
TMEM120B expression: Low -> High

> Dataset: GSE12452

HeatMap of cell type fractions in all samples Lollipop of TMEM120B expression and immune infiltrating cell level correlation result in EBV+ samples
TMEM120B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).