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HTLV1 Target gene Detail Information

> TRIM24 Gene Search Result


Gene Information
Gene Name TRIM24
Gene ID 8805
Gene Full Name tripartite motif containing 24
Gene Alias PTC6; TF1A; TIF1; RNF82; TIF1A; hTIF1; TIF1ALPHA
Transcripts ENSG00000122779
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID O15164
HGNC ID HGNC:11812
VEGA ID OTTHUMG00000155820
OMIM ID 603406
String ID 9606.ENSP00000340507
PharmGKB ID PA36519
Target gene [TRIM24] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6011935 chr7 24 24 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of TRIM24 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TRIM24 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of TRIM24 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TRIM24 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of TRIM24 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TRIM24 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).