HIV Target gene Detail Information

> USP9X Gene Search Result

Gene Information

Gene Name	USP9X
Gene ID	8239
Gene Full Name	ubiquitin specific peptidase 9 X-linked
Gene Alias	FAF; FAM; DFFRX; MRX99; MRXS99F
Transcripts	ENSG00000124486
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q93008
HGNC ID	HGNC:12632
VEGA ID	OTTHUMG00000021367
OMIM ID	300072
String ID	9606.ENSP00000316357
PharmGKB ID	PA37257

Target gene [USP9X] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008509	chrX	13	2		15	View
4014253	chrX		2		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of USP9X expression and immune infiltrating cell level correlation result in HIV+ samples
USP9X expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of USP9X expression and immune infiltrating cell level correlation result in HIV+ samples
USP9X expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).