HTLV1 Target gene Detail Information

> ZDHHC11B Gene Search Result

Gene Information

Gene Name	ZDHHC11B
Gene ID	653082
Gene Full Name	zinc finger DHHC-type containing 11B
Gene Alias	DHHC-11B
Transcripts	ENSG00000206077
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Mitochondria;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted membrane proteins
Uniport_ID	P0C7U3
HGNC ID	HGNC:32962
VEGA ID	OTTHUMG00000162148
String ID	9606.ENSP00000442373
PharmGKB ID	PA147357087

Target gene [ZDHHC11B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6004315	chr5	118	1	1	120	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ZDHHC11B expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZDHHC11B expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ZDHHC11B expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZDHHC11B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).