HBV Target gene Detail Information

> ZNF749 Gene Search Result

Gene Information

Gene Name	ZNF749
Gene ID	388567
Gene Full Name	zinc finger protein 749
Transcripts	ENSG00000186230
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nuclear membrane;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	O43361
HGNC ID	HGNC:32783
VEGA ID	OTTHUMG00000150372
String ID	9606.ENSP00000333980
PharmGKB ID	PA145007248

Target gene [ZNF749] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009598	chr19	10	3	2	15	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ZNF749 expression and immune infiltrating cell level correlation result in HBV+ samples
ZNF749 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).