HTLV1 Target gene Detail Information

> ZRANB2 Gene Search Result

Gene Information

Gene Name	ZRANB2
Gene ID	9406
Gene Full Name	zinc finger RANBP2-type containing 2
Gene Alias	ZIS; ZIS1; ZIS2; ZNF265
Transcripts	ENSG00000132485
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	O95218
HGNC ID	HGNC:13058
VEGA ID	OTTHUMG00000009660
OMIM ID	604347
String ID	9606.ENSP00000359958
PharmGKB ID	PA37636

Target gene [ZRANB2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6013684	chr1	17	1		18	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ZRANB2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZRANB2 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ZRANB2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZRANB2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).