HIV

We use limma removeBatchEffect function to remove the batch effect.


Fig.1 batch effect	Fig.2 remove batch effect

T-test is used to explore whether viral infection caused differences in immune microenvironment.

The red row means that p < 0.05.

This module analyzes the chip data, mainly including the following three aspects:
     1.limma is used to explore the influence of virus infection on gene expression.
     2.Logistic regression and L1 regularization is used to obtain genes discriminating virus infection.
     3.xcell tool is used to explore the influence of virus infection on immune microenvironment.