Evidence Details for Brain Edema
PMID Title Journal Year Abstract
21699400 Electro-acupuncture can alleviate the cerebral oedema of rat after ischemia. Brain Inj. 2011;25(9):895-900. doi: 10.3109/02699052.2011.581639. Epub 2011 Jun 23. 2011 PRIMARY OBJECTIVE: This study was designed to determine whether electro-acupuncture (EA) could alleviate cerebral oedema after cerebral ischemia. RESEARCH DESIGN: EA has been widely used for cerebrovascular disease in East Asian countries. However, whether EA might reduce cerebral oedema after stroke remains unclear. In the current study, diffusion-weighted MRI, which is a reliable method for detecting cerebral oedema, was used to determine whether EA could ameliorate cerebral oedema. METHODS AND PROCEDURES: Twelve rats with induced strokes were divided into two groups: one group with EA treatment (EA group) and one group without EA treatment (non-EA group). Both groups of rats underwent MRI scanning at the same time point following ischemia. MAIN OUTCOMES AND RESULTS: Diffusion-weighted imaging showed that the relative apparent diffusion coefficient increased significantly in the cortical and sub-cortical areas of the EA group relative to the non-EA group, indicating that EA can alleviate cerebral oedema after ischemic stroke. CONCLUSIONS: Electro-acupuncture can alleviate cerebral oedema in rats following ischemia."

Evidence Sentence: This study was designed to determine whether electro-acupuncture (EA) could alleviate cerebral oedema after cerebral ischemia.