Evidence Details for Xuehai
PMID Title Journal Year Abstract
19514190 Effects of acupuncture on expressions of the transcription factors NF-E2, YB-1, LRG47 in the SAMP10 mice. J Tradit Chin Med. 2009 Mar;29(1):54-9. doi: 10.1016/s0254-6272(09)60032-7. 2009 Mar OBJECTIVE: To explore the mechanism of acupuncture for delaying aging. METHODS: Using the senescence accelerated mouse pattern SAMP10 and the normal aging mice SAMR1 as models and applying RT-PCR and digoxin (DIG)-labeled Northern blot technique to observe expressions of NF-E2, YB-1, LRG47 genes in the forebrain, cortex and hippocampus in a 8-month old SAMR1 control group, a 8-month old SAMP10 control group, a 8-month old SAMP10 acupuncture group and a 8-month old SAMP10 non-point stimulation group. RESULTS: In the SAMP10 control group, the expressions of NF-E2, YB-1 and LRG47 were down-regulated in the forebrain, cortex and hippocampus, and after acupuncture they were up-regulated and tended to normal. CONCLUSION: The brain aging of the SAMP10 mice is related with abnormal expressions of NF-E2, YB-1 and LRG47 genes; and acupuncture can regulate the expressions of NF-E2, YB-1 and LRG47 genes, strengthening the functions of erythrocyte series, increasing the proliferation of cells and enhancing the cellular immune function in anti-bacteria, hence delaying aging."

Evidence Sentence: For the SAMP10 acupuncture group, “Tanzhong” (CV 17), “Zhongwan” (CV 12), “Qihai” (CV 6), “Xuehai” (SP 10) and Zusanli” (ST 36) were selected and located according to “The Atlas of Acupoints of Animals” drawn up by Experimental