Description The PrEA subjects received EA at PC6 at a depth of 1 cm with Deqi during the surgerypreparation stage.
Experimental Description
One hundred and seventy-eight patients, who had received intravenous patient-controlled analgesia (PCA) with Fentanyl, were assigned randomly to three groups using random numbers: a pre-operative EA group (PrEA), a post-operative EA group (PoEA), and a non-acupuncture control group (NC).
Sample Count
178
Control
Std
non-acupuncture control group (NC)(n=51)
Experiment
pre-operative EA group (PrEA)(n=45);post-operative EA group (PoEA)(n=53)
Indicator
QuestionnairePostoperative Nausea and Vomiting(PONV)
Stimulation Method
EA
Induction Method
Electroacupuncture Instrument Model
Manufacturer
Frequency
Waveform
Strength
Induction Time
Rebirth
SAEIK Medical, Korea
5 Hz
-
-
15 min
Acupuncture_Needle
Needle_Manufacturer
Needle_Depth
0.3×30 mm
Dong Bang Needle Company, Korea
1 cm
Description The acupuncture needles used in this study werestainless steel needles (Dong Bang Needle Company,0.3 mm×30 mm, Korea), and electrical stimulationwas applied for 15 min at 5 Hz using a Rebirth (SAEIK Medical, Korea) low frequency therapy apparatus.
Anesthesia Method
GA
Clinical Trial Type
random
Adverse Effects
no adverse events occurred during this study.
Effector
The incidence of nausea and vomiting was significantly lower in the PrEA group than the NC group during 48 h after surgery (P<0.01, P<0.05). The incidence of vomiting was also significantly lower in the PrEA group than the PoEA group (P<0.05). The PoEA subjects evidenced no significant differences compared with the NC subjects in terms of the incidence of nausea and vomiting (P<0.05). The severity of nausea was significantly lower in the PrEA group than in the NC and PoEA groups (P<0.05).EA on PC6 is effective in the prevention of PONV, and pre-operative acupuncture is more effective than post-operative acupuncture.
Electroacupuncture on PC6 prevents opioid-induced nausea and vomiting after laparoscopic surgery.
Abstract
OBJECTIVE: To investigate the treatment time dependence of electroacupuncture (EA) on Neiguan (PC6) for preventing postoperative nausea and vomiting (PONV). METHODS: One hundred and seventy-eight patients, who had received intravenous patient-controlled analgesia (PCA) with Fentanyl, were assigned randomly to three groups using random numbers: a pre-operative EA group (PrEA), a post-operative EA group (PoEA), and a non-acupuncture control group (NC). An anesthetist evaluated the incidence and severity of nausea and vomiting for 48 h after surgery blindly. The main outcomes were severity and freguency of PONV, which were measured with a self-reported questionnaire and a confirmation from the anesthetist. The data were analyzed with ANOVA and Z-test. RESULTS: The incidence of nausea and vomiting was significantly lower in the PrEA group than the NC group during 48 h after surgery (P<0.01, P<0.05). The incidence of vomiting was also significantly lower in the PrEA group than the PoEA group (P<0.05). The PoEA subjects evidenced no significant differences compared with the NC subjects in terms of the incidence of nausea and vomiting (P<0.05). The severity of nausea was significantly lower in the PrEA group than in the NC and PoEA groups (P<0.05). CONCLUSIONS: EA on PC6 is effective in the prevention of PONV, and pre-operative acupuncture is more effective than post-operative acupuncture."
