Ninety-six ASA Grade I — II patients scheduled for laparoscopic cholecystectomy were randomized into Neiguan (P6) electroacupoint stimulation group (treated group) and a placebo control group (placement of electrodes without electroacupoint stimulation).
Sample Count
96
Age
18-60
Control
Placebo
placebo control group (placement of electrodes without electroacupoint stimulation)(n=48)
Experiment
electroacupoint stimulation group (treated group)(n=48)
Indicator
Postoperative Nausea and Vomiting(PONV)Antiemetic dosageDegree of painVerbal rating scale(VRS)
Auxiliary Medication
All patients received fentanyl 50 ug and midazolam 2 mg by intravenous injection before entering the operating room. The anesthesiologists and care providers were blinded to the study group. Induction of anesthesia was performed by rapid tracheal intubation with propofol 1.5-2 mg/kg and rocuronium 0.6 mg/kg. Isoflurane at 0.5%-1.5% and supplemental fentanyl, of up to 4 ug/kg per hour, were used to maintain anesthesia and hemodynamic parameters (heart rate and arterial blood pressure) were kept within 20% of baseline.
at least 30 min, but no longer than 60 min before the induction of anesthesia and was continued to the end of surgery
Acupuncture_Needle
Needle_Manufacturer
Needle_Depth
-
-
-
Description PNS was turned on to determine the accurate location of the acupoint by eliciting a "de-qi" sensation. Once this was ascertained, the current was adjusted so that the patients could continue to feel the "de-qi" sensation (The stimulator was set at 2-100 Hz, 50 ms, 0.5-4 mA). The electrical stimulation at the acupoints was applied for at least 30 min, but no longer than 60 min before the induction of anesthesia and was continued to the end of surgery.
Anesthesia Method
AAA
Clinical Trial Type
random
Adverse Effects
no redness, swelling, itching, and pain, or other
relevant complications at P6 in the two groups.
Contraindications
All of the patients had normal cardiac and lung
functions with no complications of other systems
Effector
The incidence of nausea and vomiting, the dose of antiemetics and the occurrence of severe nausea were all significantly lower in the treated group compared with the control group and the score for pain was obviously reduced in patients of the treated group at 24 h post-operation (P<0.05 or P<0.01). Transcutaneous electroacupoint stimulation at P6 with the TOF mode could reduce the incidence and severity of nausea and vomiting with analgesic effects.
Evaluation of transcutaneous electroacupoint stimulation with the train-of-four mode for preventing nausea and vomiting after laparoscopic cholecystectomy.
Abstract
OBJECTIVE: To evaluate the efficacy of transcutaneous electroacupoint stimulation with a train-of-four (TOF) mode for the prevention of postoperative nausea and vomiting (PONV) in the patients undergoing laparoscopic cholecystectomy. METHODS: Ninety-six ASA Grade I - II patients scheduled for laparoscopic cholecystectomy were randomized into Neiguan (P6) electroacupoint stimulation group (treated group) and a placebo control group (placement of electrodes without electroacupoint stimulation). The anesthetic regimen was standardized by needling at Neiguan on the left side and connecting the TOF peripheral nerve stimulator. The incidence of nausea, vomiting, severity, antiemetic dosage and the degree of pain were assessed at 0, 60, 120 min, and 24 h after surgery. RESULTS: The incidence of nausea and vomiting, the dose of antiemetics and the occurrence of severe nausea were all significantly lower in the treated group compared with the control group and the score for pain was obviously reduced in patients of the treated group at 24 h post-operation (P<0.05 or P<0.01). CONCLUSION: Transcutaneous electroacupoint stimulation at P6 with the TOF mode could reduce the incidence and severity of nausea and vomiting with analgesic effects."
