Ninety unpremedicated children of ASA physical status 1 or H undergoing outpatient strabismus repair, and aged over one year, were studied. The patients were randomly assigned to three groups, to receive droperidol (Group D), acupuncture plus droperidol (Group AD), or acupuncture alone (Group A), following induction of anaesthesia.
Sample Count
90
Age
1月16日
Control
Std
droperidol (Group D)(n=30)
Experiment
acupuncture plus droperidol (Group AD)(n=30);acupuncture alone (Group A)(n=30)
Indicator
Postoperative Nausea and Vomiting(PONV)AgeGenderDuration of anaesthesiaNumber of muscles repairedDuration of stay in the PARPAR recovery scoresPostoperative drug requirementsTime to drinking fluidsTime to discharge from hospital
Auxiliary Medication
No premedication was given. All patients received intravenous thiopentone 5 mg. kg-1, atropine 0.02 mg. kg-1 and succinylcholine 1.5 mg. kg-1. Patients in Groups D and AD also received intravenous droperidol 0.075 mg. kg-1. Estimated fluid deficit and maintenance requirements were replaced with intravenous Ringer's lactate solution. Intramuscular dimenhydrinate 1.0 mg. kg-1 was available if the incidence of vomiting exceeded three episodes during any one hour. Rectal acetaminophen 10 mg. kg-1 orintramuscularcodeinephosphate 1.0mg. kg-1 was available after surgery as required for pain.
Stimulation Method
MS
Induction Method
Electroacupuncture Instrument Model
Manufacturer
Frequency
Waveform
Strength
Induction Time
-
-
-
-
-
5 min
Acupuncture_Needle
Needle_Manufacturer
Needle_Depth
0.2 mm diameter
-
-
Description Patients in Groups A and AD received acupuncture at the P6 point on the right side with five minutes manual stimulation, using sterile disposable 0.2 mm diameter acupuncture needles.
Anesthesia Method
AA
AAA
Clinical Trial Type
a randomized, patient- and observer-blinded study
Effector
There was no difference in the incidence of vomiting in the droperidol group (17% before discharge from hospital and 41% up to 48 hours after discharge), combined treatment group (17% and 34% respectively) and acupuncture group (27% and 45% respectively). Corresponding figures for the incidence of vomiting before discharge were 17%, 17% and 27% respectively; these values were also not different. The incidence of restlessness was significantly greater in children receiving droperidol (63%) or both treatments (67%) than in those receiving acupuncture alone (30%; P = 0.007). P6 acupuncture and droperidol are equally ineffective in preventing vomiting within 48 hours of paediatric strabismus repair. Droperidol is associated with increased incidence of postoperative restlessness.
Ineffectiveness of acupuncture and droperidol in preventing vomiting following strabismus repair in children.
Abstract
The antiemetic effects and side-effects of P6 acupuncture and droperidol pre-treatment were evaluated in a randomized, patient- and observer-blinded study. Ninety unpremedicated children of ASA physical status I or II undergoing outpatient strabismus repair, and aged over one year, were studied. All patients received intravenous thiopentone 5 mg.kg-1, atropine 0.02 mg.kg-1 and succinylcholine 1.5 mg.kg-1, and the trachea was intubated. Patients then received either intravenous droperidol 0.075 mg.kg-1, droperidol plus five minutes' P6 acupuncture, or acupuncture alone. Anaesthesia was maintained with nitrous oxide 66% and halothane 1.5-2.0% in oxygen with spontaneous ventilation. There was no difference in the incidence of vomiting in the droperidol group (17% before discharge from hospital and 41% up to 48 hours after discharge), combined treatment group (17% and 34% respectively) and acupuncture group (27% and 45% respectively). Corresponding figures for the incidence of vomiting before discharge were 17%, 17% and 27% respectively; these values were also not different. The incidence of restlessness was significantly greater in children receiving droperidol (63%) or both treatments (67%) than in those receiving acupuncture alone (30%; P = 0.007). P6 acupuncture and droperidol are equally ineffective in preventing vomiting within 48 hours of paediatric strabismus repair. Droperidol is associated with increased incidence of postoperative restlessness."
Souce
Can J Anaesth. 1992 Feb;39(2):151-4. doi: 10.1007/BF03008646.
