Gene symbol: NOS3

Also known as: eNOS

Organism: Oryctolagus cuniculus

NCBI gene ID: 100009498 Ensembl:ENSOCUG00000023757


GO Annotation


Category Term ID Term description
Process GO:0000003 Reproduction
Process GO:0000302 Response to reactive oxygen species
Process GO:0000303 Response to superoxide
Process GO:0000305 Response to oxygen radical
Process GO:0001101 Response to acid chemical
Process GO:0001501 Skeletal system development
Process GO:0001525 Angiogenesis
Process GO:0001542 Ovulation from ovarian follicle
Process GO:0001568 Blood vessel development
Process GO:0001654 Eye development
Process GO:0001666 Response to hypoxia
Process GO:0001667 Ameboidal-type cell migration
Process GO:0001701 In utero embryonic development
Process GO:0001894 Tissue homeostasis
Process GO:0001944 Vasculature development
Process GO:0001974 Blood vessel remodeling
Process GO:0001990 Regulation of systemic arterial blood pressure by hormone
Process GO:0002026 Regulation of the force of heart contraction
Process GO:0002028 Regulation of sodium ion transport
Process GO:0002237 Response to molecule of bacterial origin
Process GO:0003006 Developmental process involved in reproduction
Process GO:0003007 Heart morphogenesis
Process GO:0003008 System process
Process GO:0003012 Muscle system process
Process GO:0003013 Circulatory system process
Process GO:0003018 Vascular process in circulatory system
Process GO:0003044 Regulation of systemic arterial blood pressure mediated by a chemical signal
Process GO:0003057 Regulation of the force of heart contraction by chemical signal
Process GO:0003073 Regulation of systemic arterial blood pressure
Process GO:0003100 Regulation of systemic arterial blood pressure by endothelin
Process GO:0003170 Heart valve development
Process GO:0003176 Aortic valve development
Process GO:0003177 Pulmonary valve development
Process GO:0003179 Heart valve morphogenesis
Process GO:0003180 Aortic valve morphogenesis
Process GO:0003184 Pulmonary valve morphogenesis
Process GO:0003197 Endocardial cushion development
Process GO:0003203 Endocardial cushion morphogenesis
Process GO:0003205 Cardiac chamber development
Process GO:0003206 Cardiac chamber morphogenesis
Process GO:0003231 Cardiac ventricle development
Process GO:0003279 Cardiac septum development
Process GO:0003281 Ventricular septum development
Process GO:0006082 Organic acid metabolic process
Process GO:0006140 Regulation of nucleotide metabolic process
Process GO:0006520 Cellular amino acid metabolic process
Process GO:0006525 Arginine metabolic process
Process GO:0006527 Arginine catabolic process
Process GO:0006801 Superoxide metabolic process
Process GO:0006807 Nitrogen compound metabolic process
Process GO:0006809 Nitric oxide biosynthetic process
Process GO:0006810 Transport
Process GO:0006811 Ion transport
Process GO:0006812 Cation transport
Process GO:0006813 Potassium ion transport
Process GO:0006816 Calcium ion transport
Process GO:0006950 Response to stress
Process GO:0006979 Response to oxidative stress
Process GO:0007154 Cell communication
Process GO:0007165 Signal transduction
Process GO:0007166 Cell surface receptor signaling pathway
Process GO:0007263 Nitric oxide mediated signal transduction
Process GO:0007275 Multicellular organism development
Process GO:0007276 Gamete generation
Process GO:0007292 Female gamete generation
Process GO:0007423 Sensory organ development
Process GO:0007507 Heart development
Process GO:0007548 Sex differentiation
Process GO:0007565 Female pregnancy
Process GO:0007568 Aging
Process GO:0008015 Blood circulation
Process GO:0008016 Regulation of heart contraction
Process GO:0008152 Metabolic process
Process GO:0008217 Regulation of blood pressure
Process GO:0008285 Negative regulation of cell population proliferation
Process GO:0008406 Gonad development
Process GO:0008585 Female gonad development
Process GO:0009056 Catabolic process
Process GO:0009058 Biosynthetic process
Process GO:0009063 Cellular amino acid catabolic process
Process GO:0009064 Glutamine family amino acid metabolic process
Process GO:0009065 Glutamine family amino acid catabolic process
Process GO:0009266 Response to temperature stimulus
Process GO:0009408 Response to heat
Process GO:0009410 Response to xenobiotic stimulus
Process GO:0009605 Response to external stimulus
Process GO:0009607 Response to biotic stimulus
Process GO:0009611 Response to wounding
Process GO:0009612 Response to mechanical stimulus
Process GO:0009617 Response to bacterium
Process GO:0009628 Response to abiotic stimulus
Process GO:0009636 Response to toxic substance
Process GO:0009653 Anatomical structure morphogenesis
Process GO:0009719 Response to endogenous stimulus
Process GO:0009725 Response to hormone
Process GO:0009743 Response to carbohydrate
Process GO:0009746 Response to hexose
Process GO:0009750 Response to fructose
Process GO:0009790 Embryo development
Process GO:0009792 Embryo development ending in birth or egg hatching
Process GO:0009887 Animal organ morphogenesis
Process GO:0009888 Tissue development
Process GO:0009889 Regulation of biosynthetic process
Process GO:0009891 Positive regulation of biosynthetic process
Process GO:0009893 Positive regulation of metabolic process
Process GO:0009987 Cellular process
Process GO:0009991 Response to extracellular stimulus
Process GO:0010033 Response to organic substance
Process GO:0010035 Response to inorganic substance
Process GO:0010038 Response to metal ion
Process GO:0010243 Response to organonitrogen compound
Process GO:0010288 Response to lead ion
Process GO:0010468 Regulation of gene expression
Process GO:0010562 Positive regulation of phosphorus metabolic process
Process GO:0010594 Regulation of endothelial cell migration
Process GO:0010595 Positive regulation of endothelial cell migration
Process GO:0010604 Positive regulation of macromolecule metabolic process
Process GO:0010628 Positive regulation of gene expression
Process GO:0010631 Epithelial cell migration
Process GO:0010632 Regulation of epithelial cell migration
Process GO:0010634 Positive regulation of epithelial cell migration
Process GO:0010941 Regulation of cell death
Process GO:0010942 Positive regulation of cell death
Process GO:0010959 Regulation of metal ion transport
Process GO:0014070 Response to organic cyclic compound
Process GO:0014074 Response to purine-containing compound
Process GO:0014738 Regulation of muscle hyperplasia
Process GO:0014740 Negative regulation of muscle hyperplasia
Process GO:0014745 Negative regulation of muscle adaptation
Process GO:0014805 Smooth muscle adaptation
Process GO:0014806 Smooth muscle hyperplasia
Process GO:0014823 Response to activity
Process GO:0014900 Muscle hyperplasia
Process GO:0016054 Organic acid catabolic process
Process GO:0016477 Cell migration
Process GO:0019219 Regulation of nucleobase-containing compound metabolic process
Process GO:0019220 Regulation of phosphate metabolic process
Process GO:0019222 Regulation of metabolic process
Process GO:0019430 Removal of superoxide radicals
Process GO:0019752 Carboxylic acid metabolic process
Process GO:0019932 Second-messenger-mediated signaling
Process GO:0019953 Sexual reproduction
Process GO:0022414 Reproductive process
Process GO:0022602 Ovulation cycle process
Process GO:0022603 Regulation of anatomical structure morphogenesis
Process GO:0023052 Signaling
Process GO:0030001 Metal ion transport
Process GO:0030323 Respiratory tube development
Process GO:0030324 Lung development
Process GO:0030334 Regulation of cell migration
Process GO:0030335 Positive regulation of cell migration
Process GO:0030728 Ovulation
Process GO:0030808 Regulation of nucleotide biosynthetic process
Process GO:0030810 Positive regulation of nucleotide biosynthetic process
Process GO:0031279 Regulation of cyclase activity
Process GO:0031281 Positive regulation of cyclase activity
Process GO:0031282 Regulation of guanylate cyclase activity
Process GO:0031284 Positive regulation of guanylate cyclase activity
Process GO:0031323 Regulation of cellular metabolic process
Process GO:0031325 Positive regulation of cellular metabolic process
Process GO:0031326 Regulation of cellular biosynthetic process
Process GO:0031328 Positive regulation of cellular biosynthetic process
Process GO:0031644 Regulation of nervous system process
Process GO:0031663 Lipopolysaccharide-mediated signaling pathway
Process GO:0031667 Response to nutrient levels
Process GO:0031960 Response to corticosteroid
Process GO:0032026 Response to magnesium ion
Process GO:0032355 Response to estradiol
Process GO:0032496 Response to lipopolysaccharide
Process GO:0032501 Multicellular organismal process
Process GO:0032502 Developmental process
Process GO:0032504 Multicellular organism reproduction
Process GO:0032868 Response to insulin
Process GO:0032869 Cellular response to insulin stimulus
Process GO:0032870 Cellular response to hormone stimulus
Process GO:0032879 Regulation of localization
Process GO:0033554 Cellular response to stress
Process GO:0033993 Response to lipid
Process GO:0034097 Response to cytokine
Process GO:0034284 Response to monosaccharide
Process GO:0034405 Response to fluid shear stress
Process GO:0034599 Cellular response to oxidative stress
Process GO:0034605 Cellular response to heat
Process GO:0034612 Response to tumor necrosis factor
Process GO:0034614 Cellular response to reactive oxygen species
Process GO:0034641 Cellular nitrogen compound metabolic process
Process GO:0035094 Response to nicotine
Process GO:0035150 Regulation of tube size
Process GO:0035239 Tube morphogenesis
Process GO:0035295 Tube development
Process GO:0035296 Regulation of tube diameter
Process GO:0035556 Intracellular signal transduction
Process GO:0036017 Response to erythropoietin
Process GO:0036293 Response to decreased oxygen levels
Process GO:0036296 Response to increased oxygen levels
Process GO:0040012 Regulation of locomotion
Process GO:0040017 Positive regulation of locomotion
Process GO:0042127 Regulation of cell population proliferation
Process GO:0042221 Response to chemical
Process GO:0042592 Homeostatic process
Process GO:0042698 Ovulation cycle
Process GO:0042981 Regulation of apoptotic process
Process GO:0043009 Chordate embryonic development
Process GO:0043010 Camera-type eye development
Process GO:0043065 Positive regulation of apoptotic process
Process GO:0043067 Regulation of programmed cell death
Process GO:0043068 Positive regulation of programmed cell death
Process GO:0043085 Positive regulation of catalytic activity
Process GO:0043086 Negative regulation of catalytic activity
Process GO:0043200 Response to amino acid
Process GO:0043207 Response to external biotic stimulus
Process GO:0043266 Regulation of potassium ion transport
Process GO:0043267 Negative regulation of potassium ion transport
Process GO:0043269 Regulation of ion transport
Process GO:0043271 Negative regulation of ion transport
Process GO:0043434 Response to peptide hormone
Process GO:0043436 Oxoacid metabolic process
Process GO:0043500 Muscle adaptation
Process GO:0043502 Regulation of muscle adaptation
Process GO:0043535 Regulation of blood vessel endothelial cell migration
Process GO:0043536 Positive regulation of blood vessel endothelial cell migration
Process GO:0043542 Endothelial cell migration
Process GO:0044057 Regulation of system process
Process GO:0044092 Negative regulation of molecular function
Process GO:0044093 Positive regulation of molecular function
Process GO:0044237 Cellular metabolic process
Process GO:0044238 Primary metabolic process
Process GO:0044248 Cellular catabolic process
Process GO:0044249 Cellular biosynthetic process
Process GO:0044271 Cellular nitrogen compound biosynthetic process
Process GO:0044281 Small molecule metabolic process
Process GO:0044282 Small molecule catabolic process
Process GO:0044419 Biological process involved in interspecies interaction between organisms
Process GO:0044703 Multi-organism reproductive process
Process GO:0044706 Multi-multicellular organism process
Process GO:0045137 Development of primary sexual characteristics
Process GO:0045471 Response to ethanol
Process GO:0045765 Regulation of angiogenesis
Process GO:0045766 Positive regulation of angiogenesis
Process GO:0045776 Negative regulation of blood pressure
Process GO:0045935 Positive regulation of nucleobase-containing compound metabolic process
Process GO:0045937 Positive regulation of phosphate metabolic process
Process GO:0045981 Positive regulation of nucleotide metabolic process
Process GO:0046209 Nitric oxide metabolic process
Process GO:0046395 Carboxylic acid catabolic process
Process GO:0046545 Development of primary female sexual characteristics
Process GO:0046660 Female sex differentiation
Process GO:0046683 Response to organophosphorus
Process GO:0046689 Response to mercury ion
Process GO:0048511 Rhythmic process
Process GO:0048513 Animal organ development
Process GO:0048514 Blood vessel morphogenesis
Process GO:0048518 Positive regulation of biological process
Process GO:0048519 Negative regulation of biological process
Process GO:0048522 Positive regulation of cellular process
Process GO:0048523 Negative regulation of cellular process
Process GO:0048545 Response to steroid hormone
Process GO:0048583 Regulation of response to stimulus
Process GO:0048585 Negative regulation of response to stimulus
Process GO:0048608 Reproductive structure development
Process GO:0048609 Multicellular organismal reproductive process
Process GO:0048646 Anatomical structure formation involved in morphogenesis
Process GO:0048660 Regulation of smooth muscle cell proliferation
Process GO:0048662 Negative regulation of smooth muscle cell proliferation
Process GO:0048678 Response to axon injury
Process GO:0048729 Tissue morphogenesis
Process GO:0048731 System development
Process GO:0048771 Tissue remodeling
Process GO:0048856 Anatomical structure development
Process GO:0048870 Cell motility
Process GO:0048871 Multicellular organismal homeostasis
Process GO:0048872 Homeostasis of number of cells
Process GO:0048873 Homeostasis of number of cells within a tissue
Process GO:0048880 Sensory system development
Process GO:0050789 Regulation of biological process
Process GO:0050790 Regulation of catalytic activity
Process GO:0050793 Regulation of developmental process
Process GO:0050794 Regulation of cellular process
Process GO:0050886 Endocrine process
Process GO:0050896 Response to stimulus
Process GO:0051049 Regulation of transport
Process GO:0051051 Negative regulation of transport
Process GO:0051093 Negative regulation of developmental process
Process GO:0051094 Positive regulation of developmental process
Process GO:0051171 Regulation of nitrogen compound metabolic process
Process GO:0051173 Positive regulation of nitrogen compound metabolic process
Process GO:0051174 Regulation of phosphorus metabolic process
Process GO:0051179 Localization
Process GO:0051234 Establishment of localization
Process GO:0051239 Regulation of multicellular organismal process
Process GO:0051240 Positive regulation of multicellular organismal process
Process GO:0051241 Negative regulation of multicellular organismal process
Process GO:0051336 Regulation of hydrolase activity
Process GO:0051339 Regulation of lyase activity
Process GO:0051346 Negative regulation of hydrolase activity
Process GO:0051349 Positive regulation of lyase activity
Process GO:0051384 Response to glucocorticoid
Process GO:0051385 Response to mineralocorticoid
Process GO:0051412 Response to corticosterone
Process GO:0051591 Response to cAMP
Process GO:0051641 Cellular localization
Process GO:0051649 Establishment of localization in cell
Process GO:0051707 Response to other organism
Process GO:0051716 Cellular response to stimulus
Process GO:0051924 Regulation of calcium ion transport
Process GO:0051926 Negative regulation of calcium ion transport
Process GO:0055093 Response to hyperoxia
Process GO:0055094 Response to lipoprotein particle
Process GO:0060041 Retina development in camera-type eye
Process GO:0060249 Anatomical structure homeostasis
Process GO:0060255 Regulation of macromolecule metabolic process
Process GO:0060348 Bone development
Process GO:0060411 Cardiac septum morphogenesis
Process GO:0060412 Ventricular septum morphogenesis
Process GO:0060485 Mesenchyme development
Process GO:0060541 Respiratory system development
Process GO:0061458 Reproductive system development
Process GO:0062012 Regulation of small molecule metabolic process
Process GO:0062013 Positive regulation of small molecule metabolic process
Process GO:0062197 Cellular response to chemical stress
Process GO:0065007 Biological regulation
Process GO:0065008 Regulation of biological quality
Process GO:0065009 Regulation of molecular function
Process GO:0070167 Regulation of biomineral tissue development
Process GO:0070168 Negative regulation of biomineral tissue development
Process GO:0070482 Response to oxygen levels
Process GO:0070848 Response to growth factor
Process GO:0070887 Cellular response to chemical stimulus
Process GO:0071000 Response to magnetism
Process GO:0071214 Cellular response to abiotic stimulus
Process GO:0071216 Cellular response to biotic stimulus
Process GO:0071219 Cellular response to molecule of bacterial origin
Process GO:0071222 Cellular response to lipopolysaccharide
Process GO:0071241 Cellular response to inorganic substance
Process GO:0071248 Cellular response to metal ion
Process GO:0071260 Cellular response to mechanical stimulus
Process GO:0071286 Cellular response to magnesium ion
Process GO:0071310 Cellular response to organic substance
Process GO:0071320 Cellular response to cAMP
Process GO:0071345 Cellular response to cytokine stimulus
Process GO:0071356 Cellular response to tumor necrosis factor
Process GO:0071363 Cellular response to growth factor stimulus
Process GO:0071375 Cellular response to peptide hormone stimulus
Process GO:0071396 Cellular response to lipid
Process GO:0071402 Cellular response to lipoprotein particle stimulus
Process GO:0071403 Cellular response to high density lipoprotein particle stimulus
Process GO:0071404 Cellular response to low-density lipoprotein particle stimulus
Process GO:0071407 Cellular response to organic cyclic compound
Process GO:0071417 Cellular response to organonitrogen compound
Process GO:0071450 Cellular response to oxygen radical
Process GO:0071451 Cellular response to superoxide
Process GO:0071495 Cellular response to endogenous stimulus
Process GO:0071496 Cellular response to external stimulus
Process GO:0071559 Response to transforming growth factor beta
Process GO:0071560 Cellular response to transforming growth factor beta stimulus
Process GO:0071704 Organic substance metabolic process
Process GO:0072132 Mesenchyme morphogenesis
Process GO:0072359 Circulatory system development
Process GO:0072593 Reactive oxygen species metabolic process
Process GO:0080090 Regulation of primary metabolic process
Process GO:0090066 Regulation of anatomical structure size
Process GO:0090130 Tissue migration
Process GO:0090132 Epithelium migration
Process GO:0090257 Regulation of muscle system process
Process GO:0097237 Cellular response to toxic substance
Process GO:0097305 Response to alcohol
Process GO:0097746 Blood vessel diameter maintenance
Process GO:0098754 Detoxification
Process GO:0098869 Cellular oxidant detoxification
Process GO:0104004 Cellular response to environmental stimulus
Process GO:0110149 Regulation of biomineralization
Process GO:0110150 Negative regulation of biomineralization
Process GO:0150063 Visual system development
Process GO:1900371 Regulation of purine nucleotide biosynthetic process
Process GO:1900373 Positive regulation of purine nucleotide biosynthetic process
Process GO:1900542 Regulation of purine nucleotide metabolic process
Process GO:1900544 Positive regulation of purine nucleotide metabolic process
Process GO:1901342 Regulation of vasculature development
Process GO:1901556 Response to candesartan
Process GO:1901558 Response to metformin
Process GO:1901564 Organonitrogen compound metabolic process
Process GO:1901565 Organonitrogen compound catabolic process
Process GO:1901575 Organic substance catabolic process
Process GO:1901605 Alpha-amino acid metabolic process
Process GO:1901606 Alpha-amino acid catabolic process
Process GO:1901652 Response to peptide
Process GO:1901653 Cellular response to peptide
Process GO:1901654 Response to ketone
Process GO:1901655 Cellular response to ketone
Process GO:1901698 Response to nitrogen compound
Process GO:1901699 Cellular response to nitrogen compound
Process GO:1901700 Response to oxygen-containing compound
Process GO:1901701 Cellular response to oxygen-containing compound
Process GO:1902074 Response to salt
Process GO:1903522 Regulation of blood circulation
Process GO:1903576 Response to L-arginine
Process GO:1904018 Positive regulation of vasculature development
Process GO:1904647 Response to rotenone
Process GO:1904648 Cellular response to rotenone
Process GO:1905314 Semi-lunar valve development
Process GO:1990478 Response to ultrasound
Process GO:1990748 Cellular detoxification
Process GO:2000026 Regulation of multicellular organismal development
Process GO:2000145 Regulation of cell motility
Process GO:2000147 Positive regulation of cell motility
Process GO:2001057 Reactive nitrogen species metabolic process
Component GO:0005622 Intracellular anatomical structure
Component GO:0005634 Nucleus
Component GO:0005730 Nucleolus
Component GO:0005737 Cytoplasm
Component GO:0005739 Mitochondrion
Component GO:0005794 Golgi apparatus
Component GO:0005829 Cytosol
Component GO:0005856 Cytoskeleton
Component GO:0005886 Plasma membrane
Component GO:0005901 Caveola
Component GO:0012505 Endomembrane system
Component GO:0012506 Vesicle membrane
Component GO:0016020 Membrane
Component GO:0031090 Organelle membrane
Component GO:0031974 Membrane-enclosed lumen
Component GO:0031981 Nuclear lumen
Component GO:0031982 Vesicle
Component GO:0042383 Sarcolemma
Component GO:0043226 Organelle
Component GO:0043227 Membrane-bounded organelle
Component GO:0043228 Non-membrane-bounded organelle
Component GO:0043229 Intracellular organelle
Component GO:0043231 Intracellular membrane-bounded organelle
Component GO:0043232 Intracellular non-membrane-bounded organelle
Component GO:0043233 Organelle lumen
Component GO:0044853 Plasma membrane raft
Component GO:0045121 Membrane raft
Component GO:0045177 Apical part of cell
Component GO:0070013 Intracellular organelle lumen
Component GO:0071944 Cell periphery
Component GO:0098590 Plasma membrane region
Component GO:0098857 Membrane microdomain
Component GO:0110165 Cellular anatomical entity
Function GO:0000166 Nucleotide binding
Function GO:0003779 Actin binding
Function GO:0003785 Actin monomer binding
Function GO:0003824 Catalytic activity
Function GO:0004497 Monooxygenase activity
Function GO:0004517 Nitric-oxide synthase activity
Function GO:0005488 Binding
Function GO:0005515 Protein binding
Function GO:0005516 Calmodulin binding
Function GO:0008013 Beta-catenin binding
Function GO:0008092 Cytoskeletal protein binding
Function GO:0010181 FMN binding
Function GO:0016491 Oxidoreductase activity
Function GO:0016597 Amino acid binding
Function GO:0016705 Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Function GO:0016709 Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
Function GO:0019899 Enzyme binding
Function GO:0020037 Heme binding
Function GO:0031072 Heat shock protein binding
Function GO:0031406 Carboxylic acid binding
Function GO:0032553 Ribonucleotide binding
Function GO:0034617 Tetrahydrobiopterin binding
Function GO:0034618 Arginine binding
Function GO:0036094 Small molecule binding
Function GO:0043167 Ion binding
Function GO:0043168 Anion binding
Function GO:0043169 Cation binding
Function GO:0043177 Organic acid binding
Function GO:0045296 Cadherin binding
Function GO:0046872 Metal ion binding
Function GO:0046906 Tetrapyrrole binding
Function GO:0050660 Flavin adenine dinucleotide binding
Function GO:0050661 NADP binding
Function GO:0050839 Cell adhesion molecule binding
Function GO:0050998 Nitric-oxide synthase binding
Function GO:0051879 Hsp90 protein binding
Function GO:0097110 Scaffold protein binding
Function GO:0097159 Organic cyclic compound binding
Function GO:0097367 Carbohydrate derivative binding
Function GO:1901265 Nucleoside phosphate binding
Function GO:1901363 Heterocyclic compound binding
Process GO:0000003 Reproduction
Process GO:0000302 Response to reactive oxygen species
Process GO:0000303 Response to superoxide
Process GO:0000305 Response to oxygen radical
Process GO:0001525 Angiogenesis
Process GO:0001542 Ovulation from ovarian follicle
Process GO:0001568 Blood vessel development
Process GO:0001667 Ameboidal-type cell migration
Process GO:0001701 In utero embryonic development
Process GO:0001894 Tissue homeostasis
Process GO:0001944 Vasculature development
Process GO:0001974 Blood vessel remodeling
Process GO:0001990 Regulation of systemic arterial blood pressure by hormone
Process GO:0002026 Regulation of the force of heart contraction
Process GO:0002028 Regulation of sodium ion transport
Process GO:0002237 Response to molecule of bacterial origin
Process GO:0003006 Developmental process involved in reproduction
Process GO:0003007 Heart morphogenesis
Process GO:0003008 System process
Process GO:0003012 Muscle system process
Process GO:0003013 Circulatory system process
Process GO:0003018 Vascular process in circulatory system
Process GO:0003044 Regulation of systemic arterial blood pressure mediated by a chemical signal
Process GO:0003057 Regulation of the force of heart contraction by chemical signal
Process GO:0003073 Regulation of systemic arterial blood pressure
Process GO:0003100 Regulation of systemic arterial blood pressure by endothelin
Process GO:0003170 Heart valve development
Process GO:0003176 Aortic valve development
Process GO:0003177 Pulmonary valve development
Process GO:0003179 Heart valve morphogenesis
Process GO:0003180 Aortic valve morphogenesis
Process GO:0003184 Pulmonary valve morphogenesis
Process GO:0003197 Endocardial cushion development
Process GO:0003203 Endocardial cushion morphogenesis
Process GO:0003205 Cardiac chamber development
Process GO:0003206 Cardiac chamber morphogenesis
Process GO:0003231 Cardiac ventricle development
Process GO:0003279 Cardiac septum development
Process GO:0003281 Ventricular septum development
Process GO:0006082 Organic acid metabolic process
Process GO:0006140 Regulation of nucleotide metabolic process
Process GO:0006520 Cellular amino acid metabolic process
Process GO:0006525 Arginine metabolic process
Process GO:0006527 Arginine catabolic process
Process GO:0006801 Superoxide metabolic process
Process GO:0006807 Nitrogen compound metabolic process
Process GO:0006809 Nitric oxide biosynthetic process
Process GO:0006810 Transport
Process GO:0006811 Ion transport
Process GO:0006812 Cation transport
Process GO:0006813 Potassium ion transport
Process GO:0006816 Calcium ion transport
Process GO:0006950 Response to stress
Process GO:0006979 Response to oxidative stress
Process GO:0007154 Cell communication
Process GO:0007165 Signal transduction
Process GO:0007166 Cell surface receptor signaling pathway
Process GO:0007263 Nitric oxide mediated signal transduction
Process GO:0007275 Multicellular organism development
Process GO:0007276 Gamete generation
Process GO:0007292 Female gamete generation
Process GO:0007507 Heart development
Process GO:0007548 Sex differentiation
Process GO:0008015 Blood circulation
Process GO:0008016 Regulation of heart contraction
Process GO:0008152 Metabolic process
Process GO:0008217 Regulation of blood pressure
Process GO:0008285 Negative regulation of cell population proliferation
Process GO:0008406 Gonad development
Process GO:0008585 Female gonad development
Process GO:0009056 Catabolic process
Process GO:0009058 Biosynthetic process
Process GO:0009063 Cellular amino acid catabolic process
Process GO:0009064 Glutamine family amino acid metabolic process
Process GO:0009065 Glutamine family amino acid catabolic process
Process GO:0009605 Response to external stimulus
Process GO:0009607 Response to biotic stimulus
Process GO:0009617 Response to bacterium
Process GO:0009628 Response to abiotic stimulus
Process GO:0009636 Response to toxic substance
Process GO:0009653 Anatomical structure morphogenesis
Process GO:0009719 Response to endogenous stimulus
Process GO:0009725 Response to hormone
Process GO:0009790 Embryo development
Process GO:0009792 Embryo development ending in birth or egg hatching
Process GO:0009887 Animal organ morphogenesis
Process GO:0009888 Tissue development
Process GO:0009889 Regulation of biosynthetic process
Process GO:0009891 Positive regulation of biosynthetic process
Process GO:0009893 Positive regulation of metabolic process
Process GO:0009987 Cellular process
Process GO:0010033 Response to organic substance
Process GO:0010035 Response to inorganic substance
Process GO:0010468 Regulation of gene expression
Process GO:0010562 Positive regulation of phosphorus metabolic process
Process GO:0010594 Regulation of endothelial cell migration
Process GO:0010595 Positive regulation of endothelial cell migration
Process GO:0010604 Positive regulation of macromolecule metabolic process
Process GO:0010628 Positive regulation of gene expression
Process GO:0010631 Epithelial cell migration
Process GO:0010632 Regulation of epithelial cell migration
Process GO:0010634 Positive regulation of epithelial cell migration
Process GO:0010941 Regulation of cell death
Process GO:0010959 Regulation of metal ion transport
Process GO:0014738 Regulation of muscle hyperplasia
Process GO:0014745 Negative regulation of muscle adaptation
Process GO:0016054 Organic acid catabolic process
Process GO:0016477 Cell migration
Process GO:0019219 Regulation of nucleobase-containing compound metabolic process
Process GO:0019220 Regulation of phosphate metabolic process
Process GO:0019222 Regulation of metabolic process
Process GO:0019430 Removal of superoxide radicals
Process GO:0019752 Carboxylic acid metabolic process
Process GO:0019932 Second-messenger-mediated signaling
Process GO:0019953 Sexual reproduction
Process GO:0022414 Reproductive process
Process GO:0022602 Ovulation cycle process
Process GO:0022603 Regulation of anatomical structure morphogenesis
Process GO:0023052 Signaling
Process GO:0030001 Metal ion transport
Process GO:0030323 Respiratory tube development
Process GO:0030324 Lung development
Process GO:0030334 Regulation of cell migration
Process GO:0030335 Positive regulation of cell migration
Process GO:0030728 Ovulation
Process GO:0030808 Regulation of nucleotide biosynthetic process
Process GO:0030810 Positive regulation of nucleotide biosynthetic process
Process GO:0031279 Regulation of cyclase activity
Process GO:0031281 Positive regulation of cyclase activity
Process GO:0031282 Regulation of guanylate cyclase activity
Process GO:0031284 Positive regulation of guanylate cyclase activity
Process GO:0031323 Regulation of cellular metabolic process
Process GO:0031325 Positive regulation of cellular metabolic process
Process GO:0031326 Regulation of cellular biosynthetic process
Process GO:0031328 Positive regulation of cellular biosynthetic process
Process GO:0031644 Regulation of nervous system process
Process GO:0031663 Lipopolysaccharide-mediated signaling pathway
Process GO:0032496 Response to lipopolysaccharide
Process GO:0032501 Multicellular organismal process
Process GO:0032502 Developmental process
Process GO:0032504 Multicellular organism reproduction
Process GO:0032879 Regulation of localization
Process GO:0033554 Cellular response to stress
Process GO:0033993 Response to lipid
Process GO:0034405 Response to fluid shear stress
Process GO:0034599 Cellular response to oxidative stress
Process GO:0034614 Cellular response to reactive oxygen species
Process GO:0034641 Cellular nitrogen compound metabolic process
Process GO:0035150 Regulation of tube size
Process GO:0035239 Tube morphogenesis
Process GO:0035295 Tube development
Process GO:0035296 Regulation of tube diameter
Process GO:0035556 Intracellular signal transduction
Process GO:0040012 Regulation of locomotion
Process GO:0040017 Positive regulation of locomotion
Process GO:0042127 Regulation of cell population proliferation
Process GO:0042221 Response to chemical
Process GO:0042592 Homeostatic process
Process GO:0042698 Ovulation cycle
Process GO:0042981 Regulation of apoptotic process
Process GO:0043009 Chordate embryonic development
Process GO:0043067 Regulation of programmed cell death
Process GO:0043085 Positive regulation of catalytic activity
Process GO:0043086 Negative regulation of catalytic activity
Process GO:0043207 Response to external biotic stimulus
Process GO:0043266 Regulation of potassium ion transport
Process GO:0043267 Negative regulation of potassium ion transport
Process GO:0043269 Regulation of ion transport
Process GO:0043271 Negative regulation of ion transport
Process GO:0043436 Oxoacid metabolic process
Process GO:0043500 Muscle adaptation
Process GO:0043502 Regulation of muscle adaptation
Process GO:0043535 Regulation of blood vessel endothelial cell migration
Process GO:0043536 Positive regulation of blood vessel endothelial cell migration
Process GO:0043542 Endothelial cell migration
Process GO:0044057 Regulation of system process
Process GO:0044092 Negative regulation of molecular function
Process GO:0044093 Positive regulation of molecular function
Process GO:0044237 Cellular metabolic process
Process GO:0044238 Primary metabolic process
Process GO:0044248 Cellular catabolic process
Process GO:0044249 Cellular biosynthetic process
Process GO:0044271 Cellular nitrogen compound biosynthetic process
Process GO:0044281 Small molecule metabolic process
Process GO:0044282 Small molecule catabolic process
Process GO:0044419 Biological process involved in interspecies interaction between organisms
Process GO:0045137 Development of primary sexual characteristics
Process GO:0045765 Regulation of angiogenesis
Process GO:0045766 Positive regulation of angiogenesis
Process GO:0045776 Negative regulation of blood pressure
Process GO:0045935 Positive regulation of nucleobase-containing compound metabolic process
Process GO:0045937 Positive regulation of phosphate metabolic process
Process GO:0045981 Positive regulation of nucleotide metabolic process
Process GO:0046209 Nitric oxide metabolic process
Process GO:0046395 Carboxylic acid catabolic process
Process GO:0046545 Development of primary female sexual characteristics
Process GO:0046660 Female sex differentiation
Process GO:0048511 Rhythmic process
Process GO:0048513 Animal organ development
Process GO:0048514 Blood vessel morphogenesis
Process GO:0048518 Positive regulation of biological process
Process GO:0048519 Negative regulation of biological process
Process GO:0048522 Positive regulation of cellular process
Process GO:0048523 Negative regulation of cellular process
Process GO:0048583 Regulation of response to stimulus
Process GO:0048585 Negative regulation of response to stimulus
Process GO:0048608 Reproductive structure development
Process GO:0048609 Multicellular organismal reproductive process
Process GO:0048646 Anatomical structure formation involved in morphogenesis
Process GO:0048660 Regulation of smooth muscle cell proliferation
Process GO:0048662 Negative regulation of smooth muscle cell proliferation
Process GO:0048729 Tissue morphogenesis
Process GO:0048731 System development
Process GO:0048771 Tissue remodeling
Process GO:0048856 Anatomical structure development
Process GO:0048870 Cell motility
Process GO:0048871 Multicellular organismal homeostasis
Process GO:0048872 Homeostasis of number of cells
Process GO:0048873 Homeostasis of number of cells within a tissue
Process GO:0050789 Regulation of biological process
Process GO:0050790 Regulation of catalytic activity
Process GO:0050793 Regulation of developmental process
Process GO:0050794 Regulation of cellular process
Process GO:0050886 Endocrine process
Process GO:0050896 Response to stimulus
Process GO:0051049 Regulation of transport
Process GO:0051051 Negative regulation of transport
Process GO:0051093 Negative regulation of developmental process
Process GO:0051094 Positive regulation of developmental process
Process GO:0051171 Regulation of nitrogen compound metabolic process
Process GO:0051173 Positive regulation of nitrogen compound metabolic process
Process GO:0051174 Regulation of phosphorus metabolic process
Process GO:0051179 Localization
Process GO:0051234 Establishment of localization
Process GO:0051239 Regulation of multicellular organismal process
Process GO:0051240 Positive regulation of multicellular organismal process
Process GO:0051241 Negative regulation of multicellular organismal process
Process GO:0051336 Regulation of hydrolase activity
Process GO:0051339 Regulation of lyase activity
Process GO:0051346 Negative regulation of hydrolase activity
Process GO:0051349 Positive regulation of lyase activity
Process GO:0051641 Cellular localization
Process GO:0051649 Establishment of localization in cell
Process GO:0051707 Response to other organism
Process GO:0051716 Cellular response to stimulus
Process GO:0051924 Regulation of calcium ion transport
Process GO:0051926 Negative regulation of calcium ion transport
Process GO:0060249 Anatomical structure homeostasis
Process GO:0060255 Regulation of macromolecule metabolic process
Process GO:0060411 Cardiac septum morphogenesis
Process GO:0060412 Ventricular septum morphogenesis
Process GO:0060485 Mesenchyme development
Process GO:0060541 Respiratory system development
Process GO:0061458 Reproductive system development
Process GO:0062012 Regulation of small molecule metabolic process
Process GO:0062013 Positive regulation of small molecule metabolic process
Process GO:0062197 Cellular response to chemical stress
Process GO:0065007 Biological regulation
Process GO:0065008 Regulation of biological quality
Process GO:0065009 Regulation of molecular function
Process GO:0070167 Regulation of biomineral tissue development
Process GO:0070168 Negative regulation of biomineral tissue development
Process GO:0070887 Cellular response to chemical stimulus
Process GO:0071216 Cellular response to biotic stimulus
Process GO:0071219 Cellular response to molecule of bacterial origin
Process GO:0071222 Cellular response to lipopolysaccharide
Process GO:0071310 Cellular response to organic substance
Process GO:0071396 Cellular response to lipid
Process GO:0071450 Cellular response to oxygen radical
Process GO:0071451 Cellular response to superoxide
Process GO:0071704 Organic substance metabolic process
Process GO:0072132 Mesenchyme morphogenesis
Process GO:0072359 Circulatory system development
Process GO:0072593 Reactive oxygen species metabolic process
Process GO:0080090 Regulation of primary metabolic process
Process GO:0090066 Regulation of anatomical structure size
Process GO:0090130 Tissue migration
Process GO:0090132 Epithelium migration
Process GO:0090257 Regulation of muscle system process
Process GO:0097237 Cellular response to toxic substance
Process GO:0097746 Blood vessel diameter maintenance
Process GO:0098754 Detoxification
Process GO:0098869 Cellular oxidant detoxification
Process GO:0110149 Regulation of biomineralization
Process GO:0110150 Negative regulation of biomineralization
Process GO:1900371 Regulation of purine nucleotide biosynthetic process
Process GO:1900373 Positive regulation of purine nucleotide biosynthetic process
Process GO:1900542 Regulation of purine nucleotide metabolic process
Process GO:1900544 Positive regulation of purine nucleotide metabolic process
Process GO:1901342 Regulation of vasculature development
Process GO:1901564 Organonitrogen compound metabolic process
Process GO:1901565 Organonitrogen compound catabolic process
Process GO:1901575 Organic substance catabolic process
Process GO:1901605 Alpha-amino acid metabolic process
Process GO:1901606 Alpha-amino acid catabolic process
Process GO:1901700 Response to oxygen-containing compound
Process GO:1901701 Cellular response to oxygen-containing compound
Process GO:1903522 Regulation of blood circulation
Process GO:1904018 Positive regulation of vasculature development
Process GO:1905314 Semi-lunar valve development
Process GO:1990748 Cellular detoxification
Process GO:2000026 Regulation of multicellular organismal development
Process GO:2000145 Regulation of cell motility
Process GO:2000147 Positive regulation of cell motility
Process GO:2001057 Reactive nitrogen species metabolic process
Process GO:0014740 Negative regulation of muscle hyperplasia
Process GO:0014805 Smooth muscle adaptation
Process GO:0014806 Smooth muscle hyperplasia
Process GO:0014900 Muscle hyperplasia
Component GO:0005622 Intracellular anatomical structure
Component GO:0005634 Nucleus
Component GO:0005737 Cytoplasm
Component GO:0005794 Golgi apparatus
Component GO:0005829 Cytosol
Component GO:0005856 Cytoskeleton
Component GO:0005886 Plasma membrane
Component GO:0005901 Caveola
Component GO:0012505 Endomembrane system
Component GO:0012506 Vesicle membrane
Component GO:0016020 Membrane
Component GO:0031090 Organelle membrane
Component GO:0031982 Vesicle
Component GO:0043226 Organelle
Component GO:0043227 Membrane-bounded organelle
Component GO:0043228 Non-membrane-bounded organelle
Component GO:0043229 Intracellular organelle
Component GO:0043231 Intracellular membrane-bounded organelle
Component GO:0043232 Intracellular non-membrane-bounded organelle
Component GO:0044853 Plasma membrane raft
Component GO:0045121 Membrane raft
Component GO:0071944 Cell periphery
Component GO:0098590 Plasma membrane region
Component GO:0098857 Membrane microdomain
Component GO:0110165 Cellular anatomical entity
Function GO:0000166 Nucleotide binding
Function GO:0003779 Actin binding
Function GO:0003785 Actin monomer binding
Function GO:0003824 Catalytic activity
Function GO:0004497 Monooxygenase activity
Function GO:0004517 Nitric-oxide synthase activity
Function GO:0005488 Binding
Function GO:0005515 Protein binding
Function GO:0005516 Calmodulin binding
Function GO:0008092 Cytoskeletal protein binding
Function GO:0010181 FMN binding
Function GO:0016491 Oxidoreductase activity
Function GO:0016597 Amino acid binding
Function GO:0016705 Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Function GO:0016709 Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
Function GO:0020037 Heme binding
Function GO:0031406 Carboxylic acid binding
Function GO:0032553 Ribonucleotide binding
Function GO:0034617 Tetrahydrobiopterin binding
Function GO:0034618 Arginine binding
Function GO:0036094 Small molecule binding
Function GO:0043167 Ion binding
Function GO:0043168 Anion binding
Function GO:0043169 Cation binding
Function GO:0043177 Organic acid binding
Function GO:0046872 Metal ion binding
Function GO:0046906 Tetrapyrrole binding
Function GO:0050660 Flavin adenine dinucleotide binding
Function GO:0050661 NADP binding
Function GO:0097110 Scaffold protein binding
Function GO:0097159 Organic cyclic compound binding
Function GO:0097367 Carbohydrate derivative binding
Function GO:1901265 Nucleoside phosphate binding
Function GO:1901363 Heterocyclic compound binding

Pathway annotation


Category Term ID Term description
RCTM RNO-109582 Hemostasis
RCTM RNO-1222556 ROS and RNS production in phagocytes
RCTM RNO-1430728 Metabolism
RCTM RNO-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
RCTM RNO-162582 Signal Transduction
RCTM RNO-168249 Innate Immune System
RCTM RNO-168256 Immune System
RCTM RNO-194138 Signaling by VEGF
RCTM RNO-196854 Metabolism of vitamins and cofactors
RCTM RNO-202131 Metabolism of nitric oxide: NOS3 activation and regulation
RCTM RNO-203615 eNOS activation
RCTM RNO-203641 NOSTRIN mediated eNOS trafficking
RCTM RNO-203754 NOSIP mediated eNOS trafficking
RCTM RNO-392154 Nitric oxide stimulates guanylate cyclase
RCTM RNO-418346 Platelet homeostasis
RCTM RNO-4420097 VEGFA-VEGFR2 Pathway
RCTM RNO-5218920 VEGFR2 mediated vascular permeability
RCTM RNO-8939211 ESR-mediated signaling
RCTM RNO-8978934 Metabolism of cofactors
RCTM RNO-9006931 Signaling by Nuclear Receptors
RCTM RNO-9006934 Signaling by Receptor Tyrosine Kinases
RCTM RNO-9009391 Extra-nuclear estrogen signaling
WikiPathways WP140 Myometrial relaxation and contraction pathways
WikiPathways WP1964 VEGFR-3 signaling
WikiPathways WP1965 VEGF-receptor signal transduction
WikiPathways WP3887 Angiotensin II signaling (acute) in thick ascending limbs
WikiPathways WP557 ACE inhibitor pathway
RCTM MAP-109582 Hemostasis
RCTM MAP-1222556 ROS and RNS production in phagocytes
RCTM MAP-1430728 Metabolism
RCTM MAP-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
RCTM MAP-162582 Signal Transduction
RCTM MAP-168249 Innate Immune System
RCTM MAP-168256 Immune System
RCTM MAP-194138 Signaling by VEGF
RCTM MAP-196854 Metabolism of vitamins and cofactors
RCTM MAP-202131 Metabolism of nitric oxide: NOS3 activation and regulation
RCTM MAP-203615 eNOS activation
RCTM MAP-203641 NOSTRIN mediated eNOS trafficking
RCTM MAP-203754 NOSIP mediated eNOS trafficking
RCTM MAP-392154 Nitric oxide stimulates guanylate cyclase
RCTM MAP-418346 Platelet homeostasis
RCTM MAP-4420097 VEGFA-VEGFR2 Pathway
RCTM MAP-5218920 VEGFR2 mediated vascular permeability
RCTM MAP-8939211 ESR-mediated signaling
RCTM MAP-8978934 Metabolism of cofactors
RCTM MAP-9006931 Signaling by Nuclear Receptors
RCTM MAP-9006934 Signaling by Receptor Tyrosine Kinases
RCTM MAP-9009391 Extra-nuclear estrogen signaling
KEGG ocu00220 Arginine biosynthesis
KEGG ocu00330 Arginine and proline metabolism
KEGG ocu01100 Metabolic pathways
KEGG ocu04020 Calcium signaling pathway
KEGG ocu04022 cGMP-PKG signaling pathway
KEGG ocu04066 HIF-1 signaling pathway
KEGG ocu04071 Sphingolipid signaling pathway
KEGG ocu04151 PI3K-Akt signaling pathway
KEGG ocu04370 VEGF signaling pathway
KEGG ocu04371 Apelin signaling pathway
KEGG ocu04611 Platelet activation
KEGG ocu04915 Estrogen signaling pathway
KEGG ocu04921 Oxytocin signaling pathway
KEGG ocu04926 Relaxin signaling pathway
KEGG ocu04931 Insulin resistance
KEGG ocu04933 AGE-RAGE signaling pathway in diabetic complications
KEGG ocu05415 Diabetic cardiomyopathy
KEGG ocu05417 Lipid and atherosclerosis
KEGG ocu05418 Fluid shear stress and atherosclerosis
KEGG rno00220 Arginine biosynthesis
KEGG rno00330 Arginine and proline metabolism
KEGG rno01100 Metabolic pathways
KEGG rno04020 Calcium signaling pathway
KEGG rno04022 cGMP-PKG signaling pathway
KEGG rno04066 HIF-1 signaling pathway
KEGG rno04071 Sphingolipid signaling pathway
KEGG rno04151 PI3K-Akt signaling pathway
KEGG rno04370 VEGF signaling pathway
KEGG rno04371 Apelin signaling pathway
KEGG rno04611 Platelet activation
KEGG rno04915 Estrogen signaling pathway
KEGG rno04921 Oxytocin signaling pathway
KEGG rno04926 Relaxin signaling pathway
KEGG rno04931 Insulin resistance
KEGG rno04933 AGE-RAGE signaling pathway in diabetic complications
KEGG rno05415 Diabetic cardiomyopathy
KEGG rno05417 Lipid and atherosclerosis
KEGG rno05418 Fluid shear stress and atherosclerosis