Gene symbol: PIK3CA

Organism: Oryctolagus cuniculus

NCBI gene ID: 100337822 Ensembl:ENSOCUG00000010631


GO Annotation


Category Term ID Term description
Process GO:0001101 Response to acid chemical
Process GO:0001525 Angiogenesis
Process GO:0001568 Blood vessel development
Process GO:0001678 Cellular glucose homeostasis
Process GO:0001889 Liver development
Process GO:0001932 Regulation of protein phosphorylation
Process GO:0001934 Positive regulation of protein phosphorylation
Process GO:0001944 Vasculature development
Process GO:0003008 System process
Process GO:0003012 Muscle system process
Process GO:0003013 Circulatory system process
Process GO:0003015 Heart process
Process GO:0005975 Carbohydrate metabolic process
Process GO:0005996 Monosaccharide metabolic process
Process GO:0006006 Glucose metabolic process
Process GO:0006629 Lipid metabolic process
Process GO:0006644 Phospholipid metabolic process
Process GO:0006650 Glycerophospholipid metabolic process
Process GO:0006661 Phosphatidylinositol biosynthetic process
Process GO:0006793 Phosphorus metabolic process
Process GO:0006796 Phosphate-containing compound metabolic process
Process GO:0006810 Transport
Process GO:0006909 Phagocytosis
Process GO:0006936 Muscle contraction
Process GO:0006941 Striated muscle contraction
Process GO:0006950 Response to stress
Process GO:0006996 Organelle organization
Process GO:0007010 Cytoskeleton organization
Process GO:0007154 Cell communication
Process GO:0007165 Signal transduction
Process GO:0007166 Cell surface receptor signaling pathway
Process GO:0007167 Enzyme-linked receptor protein signaling pathway
Process GO:0007169 Transmembrane receptor protein tyrosine kinase signaling pathway
Process GO:0007275 Multicellular organism development
Process GO:0008015 Blood circulation
Process GO:0008064 Regulation of actin polymerization or depolymerization
Process GO:0008152 Metabolic process
Process GO:0008284 Positive regulation of cell population proliferation
Process GO:0008610 Lipid biosynthetic process
Process GO:0008654 Phospholipid biosynthetic process
Process GO:0009058 Biosynthetic process
Process GO:0009415 Response to water
Process GO:0009605 Response to external stimulus
Process GO:0009612 Response to mechanical stimulus
Process GO:0009628 Response to abiotic stimulus
Process GO:0009653 Anatomical structure morphogenesis
Process GO:0009719 Response to endogenous stimulus
Process GO:0009725 Response to hormone
Process GO:0009743 Response to carbohydrate
Process GO:0009746 Response to hexose
Process GO:0009749 Response to glucose
Process GO:0009888 Tissue development
Process GO:0009892 Negative regulation of metabolic process
Process GO:0009893 Positive regulation of metabolic process
Process GO:0009966 Regulation of signal transduction
Process GO:0009967 Positive regulation of signal transduction
Process GO:0009987 Cellular process
Process GO:0010033 Response to organic substance
Process GO:0010035 Response to inorganic substance
Process GO:0010243 Response to organonitrogen compound
Process GO:0010468 Regulation of gene expression
Process GO:0010562 Positive regulation of phosphorus metabolic process
Process GO:0010604 Positive regulation of macromolecule metabolic process
Process GO:0010605 Negative regulation of macromolecule metabolic process
Process GO:0010629 Negative regulation of gene expression
Process GO:0010639 Negative regulation of organelle organization
Process GO:0010646 Regulation of cell communication
Process GO:0010647 Positive regulation of cell communication
Process GO:0010847 Regulation of chromatin assembly
Process GO:0010941 Regulation of cell death
Process GO:0014065 Phosphatidylinositol 3-kinase signaling
Process GO:0014070 Response to organic cyclic compound
Process GO:0014823 Response to activity
Process GO:0014854 Response to inactivity
Process GO:0014870 Response to muscle inactivity
Process GO:0016043 Cellular component organization
Process GO:0016192 Vesicle-mediated transport
Process GO:0016310 Phosphorylation
Process GO:0016477 Cell migration
Process GO:0019219 Regulation of nucleobase-containing compound metabolic process
Process GO:0019220 Regulation of phosphate metabolic process
Process GO:0019222 Regulation of metabolic process
Process GO:0019318 Hexose metabolic process
Process GO:0019637 Organophosphate metabolic process
Process GO:0019725 Cellular homeostasis
Process GO:0023051 Regulation of signaling
Process GO:0023052 Signaling
Process GO:0023056 Positive regulation of signaling
Process GO:0030029 Actin filament-based process
Process GO:0030036 Actin cytoskeleton organization
Process GO:0030048 Actin filament-based movement
Process GO:0030832 Regulation of actin filament length
Process GO:0030834 Regulation of actin filament depolymerization
Process GO:0030835 Negative regulation of actin filament depolymerization
Process GO:0031323 Regulation of cellular metabolic process
Process GO:0031325 Positive regulation of cellular metabolic process
Process GO:0031399 Regulation of protein modification process
Process GO:0031401 Positive regulation of protein modification process
Process GO:0031445 Regulation of heterochromatin assembly
Process GO:0031960 Response to corticosteroid
Process GO:0032147 Activation of protein kinase activity
Process GO:0032501 Multicellular organismal process
Process GO:0032502 Developmental process
Process GO:0032535 Regulation of cellular component size
Process GO:0032956 Regulation of actin cytoskeleton organization
Process GO:0032970 Regulation of actin filament-based process
Process GO:0033043 Regulation of organelle organization
Process GO:0033135 Regulation of peptidyl-serine phosphorylation
Process GO:0033138 Positive regulation of peptidyl-serine phosphorylation
Process GO:0033500 Carbohydrate homeostasis
Process GO:0033554 Cellular response to stress
Process GO:0033674 Positive regulation of kinase activity
Process GO:0033993 Response to lipid
Process GO:0034284 Response to monosaccharide
Process GO:0035239 Tube morphogenesis
Process GO:0035295 Tube development
Process GO:0035556 Intracellular signal transduction
Process GO:0035924 Cellular response to vascular endothelial growth factor stimulus
Process GO:0035994 Response to muscle stretch
Process GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process
Process GO:0038084 Vascular endothelial growth factor signaling pathway
Process GO:0040008 Regulation of growth
Process GO:0040014 Regulation of multicellular organism growth
Process GO:0042127 Regulation of cell population proliferation
Process GO:0042221 Response to chemical
Process GO:0042325 Regulation of phosphorylation
Process GO:0042327 Positive regulation of phosphorylation
Process GO:0042592 Homeostatic process
Process GO:0042593 Glucose homeostasis
Process GO:0042981 Regulation of apoptotic process
Process GO:0043066 Negative regulation of apoptotic process
Process GO:0043067 Regulation of programmed cell death
Process GO:0043069 Negative regulation of programmed cell death
Process GO:0043085 Positive regulation of catalytic activity
Process GO:0043200 Response to amino acid
Process GO:0043201 Response to leucine
Process GO:0043242 Negative regulation of protein-containing complex disassembly
Process GO:0043244 Regulation of protein-containing complex disassembly
Process GO:0043457 Regulation of cellular respiration
Process GO:0043467 Regulation of generation of precursor metabolites and energy
Process GO:0043491 Protein kinase B signaling
Process GO:0043523 Regulation of neuron apoptotic process
Process GO:0043524 Negative regulation of neuron apoptotic process
Process GO:0043549 Regulation of kinase activity
Process GO:0044028 DNA hypomethylation
Process GO:0044029 Hypomethylation of CpG island
Process GO:0044030 Regulation of DNA methylation
Process GO:0044087 Regulation of cellular component biogenesis
Process GO:0044093 Positive regulation of molecular function
Process GO:0044237 Cellular metabolic process
Process GO:0044238 Primary metabolic process
Process GO:0044249 Cellular biosynthetic process
Process GO:0044255 Cellular lipid metabolic process
Process GO:0044281 Small molecule metabolic process
Process GO:0045017 Glycerolipid biosynthetic process
Process GO:0045859 Regulation of protein kinase activity
Process GO:0045860 Positive regulation of protein kinase activity
Process GO:0045937 Positive regulation of phosphate metabolic process
Process GO:0046474 Glycerophospholipid biosynthetic process
Process GO:0046486 Glycerolipid metabolic process
Process GO:0046488 Phosphatidylinositol metabolic process
Process GO:0046854 Phosphatidylinositol phosphate biosynthetic process
Process GO:0048015 Phosphatidylinositol-mediated signaling
Process GO:0048017 Inositol lipid-mediated signaling
Process GO:0048513 Animal organ development
Process GO:0048514 Blood vessel morphogenesis
Process GO:0048518 Positive regulation of biological process
Process GO:0048519 Negative regulation of biological process
Process GO:0048522 Positive regulation of cellular process
Process GO:0048523 Negative regulation of cellular process
Process GO:0048545 Response to steroid hormone
Process GO:0048583 Regulation of response to stimulus
Process GO:0048584 Positive regulation of response to stimulus
Process GO:0048638 Regulation of developmental growth
Process GO:0048646 Anatomical structure formation involved in morphogenesis
Process GO:0048660 Regulation of smooth muscle cell proliferation
Process GO:0048661 Positive regulation of smooth muscle cell proliferation
Process GO:0048731 System development
Process GO:0048732 Gland development
Process GO:0048856 Anatomical structure development
Process GO:0048870 Cell motility
Process GO:0048871 Multicellular organismal homeostasis
Process GO:0048878 Chemical homeostasis
Process GO:0050789 Regulation of biological process
Process GO:0050790 Regulation of catalytic activity
Process GO:0050793 Regulation of developmental process
Process GO:0050794 Regulation of cellular process
Process GO:0050896 Response to stimulus
Process GO:0051052 Regulation of DNA metabolic process
Process GO:0051128 Regulation of cellular component organization
Process GO:0051129 Negative regulation of cellular component organization
Process GO:0051171 Regulation of nitrogen compound metabolic process
Process GO:0051173 Positive regulation of nitrogen compound metabolic process
Process GO:0051174 Regulation of phosphorus metabolic process
Process GO:0051179 Localization
Process GO:0051234 Establishment of localization
Process GO:0051239 Regulation of multicellular organismal process
Process GO:0051246 Regulation of protein metabolic process
Process GO:0051247 Positive regulation of protein metabolic process
Process GO:0051338 Regulation of transferase activity
Process GO:0051347 Positive regulation of transferase activity
Process GO:0051384 Response to glucocorticoid
Process GO:0051493 Regulation of cytoskeleton organization
Process GO:0051494 Negative regulation of cytoskeleton organization
Process GO:0051599 Response to hydrostatic pressure
Process GO:0051716 Cellular response to stimulus
Process GO:0051896 Regulation of protein kinase B signaling
Process GO:0051897 Positive regulation of protein kinase B signaling
Process GO:0055082 Cellular chemical homeostasis
Process GO:0055119 Relaxation of cardiac muscle
Process GO:0060047 Heart contraction
Process GO:0060048 Cardiac muscle contraction
Process GO:0060255 Regulation of macromolecule metabolic process
Process GO:0060548 Negative regulation of cell death
Process GO:0060612 Adipose tissue development
Process GO:0061008 Hepaticobiliary system development
Process GO:0061448 Connective tissue development
Process GO:0062197 Cellular response to chemical stress
Process GO:0065007 Biological regulation
Process GO:0065008 Regulation of biological quality
Process GO:0065009 Regulation of molecular function
Process GO:0070252 Actin-mediated cell contraction
Process GO:0070542 Response to fatty acid
Process GO:0070848 Response to growth factor
Process GO:0070887 Cellular response to chemical stimulus
Process GO:0071214 Cellular response to abiotic stimulus
Process GO:0071229 Cellular response to acid chemical
Process GO:0071310 Cellular response to organic substance
Process GO:0071322 Cellular response to carbohydrate stimulus
Process GO:0071326 Cellular response to monosaccharide stimulus
Process GO:0071331 Cellular response to hexose stimulus
Process GO:0071333 Cellular response to glucose stimulus
Process GO:0071363 Cellular response to growth factor stimulus
Process GO:0071462 Cellular response to water stimulus
Process GO:0071464 Cellular response to hydrostatic pressure
Process GO:0071548 Response to dexamethasone
Process GO:0071704 Organic substance metabolic process
Process GO:0071840 Cellular component organization or biogenesis
Process GO:0072359 Circulatory system development
Process GO:0080090 Regulation of primary metabolic process
Process GO:0086003 Cardiac muscle cell contraction
Process GO:0090066 Regulation of anatomical structure size
Process GO:0090075 Relaxation of muscle
Process GO:0090407 Organophosphate biosynthetic process
Process GO:0097009 Energy homeostasis
Process GO:0104004 Cellular response to environmental stimulus
Process GO:0110053 Regulation of actin filament organization
Process GO:0120261 Regulation of heterochromatin organization
Process GO:1901214 Regulation of neuron death
Process GO:1901215 Negative regulation of neuron death
Process GO:1901576 Organic substance biosynthetic process
Process GO:1901654 Response to ketone
Process GO:1901698 Response to nitrogen compound
Process GO:1901700 Response to oxygen-containing compound
Process GO:1901701 Cellular response to oxygen-containing compound
Process GO:1901879 Regulation of protein depolymerization
Process GO:1901880 Negative regulation of protein depolymerization
Process GO:1902275 Regulation of chromatin organization
Process GO:1902531 Regulation of intracellular signal transduction
Process GO:1902533 Positive regulation of intracellular signal transduction
Process GO:1902903 Regulation of supramolecular fiber organization
Process GO:1902904 Negative regulation of supramolecular fiber organization
Process GO:1903544 Response to butyrate
Process GO:2000209 Regulation of anoikis
Process GO:2000269 Regulation of fibroblast apoptotic process
Process GO:2000270 Negative regulation of fibroblast apoptotic process
Process GO:2000653 Regulation of genetic imprinting
Process GO:2000811 Negative regulation of anoikis
Component GO:0005622 Intracellular anatomical structure
Component GO:0005737 Cytoplasm
Component GO:0005829 Cytosol
Component GO:0005886 Plasma membrane
Component GO:0005911 Cell-cell junction
Component GO:0005942 Phosphatidylinositol 3-kinase complex
Component GO:0005943 Phosphatidylinositol 3-kinase complex, class IA
Component GO:0005944 Phosphatidylinositol 3-kinase complex, class IB
Component GO:0014704 Intercalated disc
Component GO:0016020 Membrane
Component GO:0019898 Extrinsic component of membrane
Component GO:0030027 Lamellipodium
Component GO:0030054 Cell junction
Component GO:0031252 Cell leading edge
Component GO:0032991 Protein-containing complex
Component GO:0042995 Cell projection
Component GO:0044291 Cell-cell contact zone
Component GO:0061695 Transferase complex, transferring phosphorus-containing groups
Component GO:0070161 Anchoring junction
Component GO:0071944 Cell periphery
Component GO:0097651 Phosphatidylinositol 3-kinase complex, class I
Component GO:0098796 Membrane protein complex
Component GO:0110165 Cellular anatomical entity
Component GO:0120025 Plasma membrane bounded cell projection
Component GO:1902494 Catalytic complex
Component GO:1990234 Transferase complex
Function GO:0000166 Nucleotide binding
Function GO:0003824 Catalytic activity
Function GO:0004672 Protein kinase activity
Function GO:0004674 Protein serine/threonine kinase activity
Function GO:0005488 Binding
Function GO:0005515 Protein binding
Function GO:0005524 ATP binding
Function GO:0008047 Enzyme activator activity
Function GO:0016301 Kinase activity
Function GO:0016303 1-phosphatidylinositol-3-kinase activity
Function GO:0016307 Phosphatidylinositol phosphate kinase activity
Function GO:0016740 Transferase activity
Function GO:0016772 Transferase activity, transferring phosphorus-containing groups
Function GO:0016773 Phosphotransferase activity, alcohol group as acceptor
Function GO:0017076 Purine nucleotide binding
Function GO:0019207 Kinase regulator activity
Function GO:0019209 Kinase activator activity
Function GO:0019887 Protein kinase regulator activity
Function GO:0030234 Enzyme regulator activity
Function GO:0030295 Protein kinase activator activity
Function GO:0030554 Adenyl nucleotide binding
Function GO:0032553 Ribonucleotide binding
Function GO:0032555 Purine ribonucleotide binding
Function GO:0032559 Adenyl ribonucleotide binding
Function GO:0035004 Phosphatidylinositol 3-kinase activity
Function GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity
Function GO:0035639 Purine ribonucleoside triphosphate binding
Function GO:0036094 Small molecule binding
Function GO:0043167 Ion binding
Function GO:0043168 Anion binding
Function GO:0043560 Insulin receptor substrate binding
Function GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
Function GO:0052742 Phosphatidylinositol kinase activity
Function GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity
Function GO:0052813 Phosphatidylinositol bisphosphate kinase activity
Function GO:0097159 Organic cyclic compound binding
Function GO:0097367 Carbohydrate derivative binding
Function GO:0098772 Molecular function regulator activity
Function GO:0106310 Protein serine kinase activity
Function GO:0140096 Catalytic activity, acting on a protein
Function GO:1901265 Nucleoside phosphate binding
Function GO:1901363 Heterocyclic compound binding
Process GO:0001101 Response to acid chemical
Process GO:0001525 Angiogenesis
Process GO:0001568 Blood vessel development
Process GO:0001678 Cellular glucose homeostasis
Process GO:0001889 Liver development
Process GO:0001932 Regulation of protein phosphorylation
Process GO:0001934 Positive regulation of protein phosphorylation
Process GO:0001944 Vasculature development
Process GO:0003008 System process
Process GO:0003012 Muscle system process
Process GO:0003013 Circulatory system process
Process GO:0003015 Heart process
Process GO:0005975 Carbohydrate metabolic process
Process GO:0005996 Monosaccharide metabolic process
Process GO:0006006 Glucose metabolic process
Process GO:0006629 Lipid metabolic process
Process GO:0006644 Phospholipid metabolic process
Process GO:0006650 Glycerophospholipid metabolic process
Process GO:0006661 Phosphatidylinositol biosynthetic process
Process GO:0006793 Phosphorus metabolic process
Process GO:0006796 Phosphate-containing compound metabolic process
Process GO:0006810 Transport
Process GO:0006909 Phagocytosis
Process GO:0006936 Muscle contraction
Process GO:0006941 Striated muscle contraction
Process GO:0006950 Response to stress
Process GO:0006996 Organelle organization
Process GO:0007010 Cytoskeleton organization
Process GO:0007154 Cell communication
Process GO:0007165 Signal transduction
Process GO:0007166 Cell surface receptor signaling pathway
Process GO:0007167 Enzyme-linked receptor protein signaling pathway
Process GO:0007169 Transmembrane receptor protein tyrosine kinase signaling pathway
Process GO:0007275 Multicellular organism development
Process GO:0008015 Blood circulation
Process GO:0008064 Regulation of actin polymerization or depolymerization
Process GO:0008152 Metabolic process
Process GO:0008284 Positive regulation of cell population proliferation
Process GO:0008610 Lipid biosynthetic process
Process GO:0008654 Phospholipid biosynthetic process
Process GO:0009058 Biosynthetic process
Process GO:0009415 Response to water
Process GO:0009605 Response to external stimulus
Process GO:0009612 Response to mechanical stimulus
Process GO:0009628 Response to abiotic stimulus
Process GO:0009653 Anatomical structure morphogenesis
Process GO:0009719 Response to endogenous stimulus
Process GO:0009725 Response to hormone
Process GO:0009743 Response to carbohydrate
Process GO:0009746 Response to hexose
Process GO:0009749 Response to glucose
Process GO:0009888 Tissue development
Process GO:0009892 Negative regulation of metabolic process
Process GO:0009893 Positive regulation of metabolic process
Process GO:0009966 Regulation of signal transduction
Process GO:0009967 Positive regulation of signal transduction
Process GO:0009987 Cellular process
Process GO:0010033 Response to organic substance
Process GO:0010035 Response to inorganic substance
Process GO:0010243 Response to organonitrogen compound
Process GO:0010468 Regulation of gene expression
Process GO:0010562 Positive regulation of phosphorus metabolic process
Process GO:0010604 Positive regulation of macromolecule metabolic process
Process GO:0010605 Negative regulation of macromolecule metabolic process
Process GO:0010629 Negative regulation of gene expression
Process GO:0010639 Negative regulation of organelle organization
Process GO:0010646 Regulation of cell communication
Process GO:0010647 Positive regulation of cell communication
Process GO:0010847 Regulation of chromatin assembly
Process GO:0010941 Regulation of cell death
Process GO:0014065 Phosphatidylinositol 3-kinase signaling
Process GO:0014070 Response to organic cyclic compound
Process GO:0014823 Response to activity
Process GO:0014854 Response to inactivity
Process GO:0014870 Response to muscle inactivity
Process GO:0016043 Cellular component organization
Process GO:0016192 Vesicle-mediated transport
Process GO:0016310 Phosphorylation
Process GO:0016477 Cell migration
Process GO:0019219 Regulation of nucleobase-containing compound metabolic process
Process GO:0019220 Regulation of phosphate metabolic process
Process GO:0019222 Regulation of metabolic process
Process GO:0019318 Hexose metabolic process
Process GO:0019637 Organophosphate metabolic process
Process GO:0019725 Cellular homeostasis
Process GO:0023051 Regulation of signaling
Process GO:0023052 Signaling
Process GO:0023056 Positive regulation of signaling
Process GO:0030029 Actin filament-based process
Process GO:0030036 Actin cytoskeleton organization
Process GO:0030048 Actin filament-based movement
Process GO:0030832 Regulation of actin filament length
Process GO:0030834 Regulation of actin filament depolymerization
Process GO:0030835 Negative regulation of actin filament depolymerization
Process GO:0031323 Regulation of cellular metabolic process
Process GO:0031325 Positive regulation of cellular metabolic process
Process GO:0031399 Regulation of protein modification process
Process GO:0031401 Positive regulation of protein modification process
Process GO:0031445 Regulation of heterochromatin assembly
Process GO:0031960 Response to corticosteroid
Process GO:0032147 Activation of protein kinase activity
Process GO:0032501 Multicellular organismal process
Process GO:0032502 Developmental process
Process GO:0032535 Regulation of cellular component size
Process GO:0032956 Regulation of actin cytoskeleton organization
Process GO:0032970 Regulation of actin filament-based process
Process GO:0033043 Regulation of organelle organization
Process GO:0033135 Regulation of peptidyl-serine phosphorylation
Process GO:0033138 Positive regulation of peptidyl-serine phosphorylation
Process GO:0033500 Carbohydrate homeostasis
Process GO:0033554 Cellular response to stress
Process GO:0033674 Positive regulation of kinase activity
Process GO:0033993 Response to lipid
Process GO:0034284 Response to monosaccharide
Process GO:0035239 Tube morphogenesis
Process GO:0035295 Tube development
Process GO:0035556 Intracellular signal transduction
Process GO:0035924 Cellular response to vascular endothelial growth factor stimulus
Process GO:0035994 Response to muscle stretch
Process GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process
Process GO:0038084 Vascular endothelial growth factor signaling pathway
Process GO:0040008 Regulation of growth
Process GO:0040014 Regulation of multicellular organism growth
Process GO:0042127 Regulation of cell population proliferation
Process GO:0042221 Response to chemical
Process GO:0042325 Regulation of phosphorylation
Process GO:0042327 Positive regulation of phosphorylation
Process GO:0042592 Homeostatic process
Process GO:0042593 Glucose homeostasis
Process GO:0042981 Regulation of apoptotic process
Process GO:0043066 Negative regulation of apoptotic process
Process GO:0043067 Regulation of programmed cell death
Process GO:0043069 Negative regulation of programmed cell death
Process GO:0043085 Positive regulation of catalytic activity
Process GO:0043200 Response to amino acid
Process GO:0043201 Response to leucine
Process GO:0043242 Negative regulation of protein-containing complex disassembly
Process GO:0043244 Regulation of protein-containing complex disassembly
Process GO:0043457 Regulation of cellular respiration
Process GO:0043467 Regulation of generation of precursor metabolites and energy
Process GO:0043491 Protein kinase B signaling
Process GO:0043523 Regulation of neuron apoptotic process
Process GO:0043524 Negative regulation of neuron apoptotic process
Process GO:0043549 Regulation of kinase activity
Process GO:0044028 DNA hypomethylation
Process GO:0044029 Hypomethylation of CpG island
Process GO:0044030 Regulation of DNA methylation
Process GO:0044087 Regulation of cellular component biogenesis
Process GO:0044093 Positive regulation of molecular function
Process GO:0044237 Cellular metabolic process
Process GO:0044238 Primary metabolic process
Process GO:0044249 Cellular biosynthetic process
Process GO:0044255 Cellular lipid metabolic process
Process GO:0044281 Small molecule metabolic process
Process GO:0045017 Glycerolipid biosynthetic process
Process GO:0045859 Regulation of protein kinase activity
Process GO:0045860 Positive regulation of protein kinase activity
Process GO:0045937 Positive regulation of phosphate metabolic process
Process GO:0046474 Glycerophospholipid biosynthetic process
Process GO:0046486 Glycerolipid metabolic process
Process GO:0046488 Phosphatidylinositol metabolic process
Process GO:0046854 Phosphatidylinositol phosphate biosynthetic process
Process GO:0048015 Phosphatidylinositol-mediated signaling
Process GO:0048017 Inositol lipid-mediated signaling
Process GO:0048513 Animal organ development
Process GO:0048514 Blood vessel morphogenesis
Process GO:0048518 Positive regulation of biological process
Process GO:0048519 Negative regulation of biological process
Process GO:0048522 Positive regulation of cellular process
Process GO:0048523 Negative regulation of cellular process
Process GO:0048545 Response to steroid hormone
Process GO:0048583 Regulation of response to stimulus
Process GO:0048584 Positive regulation of response to stimulus
Process GO:0048638 Regulation of developmental growth
Process GO:0048646 Anatomical structure formation involved in morphogenesis
Process GO:0048660 Regulation of smooth muscle cell proliferation
Process GO:0048661 Positive regulation of smooth muscle cell proliferation
Process GO:0048731 System development
Process GO:0048732 Gland development
Process GO:0048856 Anatomical structure development
Process GO:0048870 Cell motility
Process GO:0048871 Multicellular organismal homeostasis
Process GO:0048878 Chemical homeostasis
Process GO:0050789 Regulation of biological process
Process GO:0050790 Regulation of catalytic activity
Process GO:0050793 Regulation of developmental process
Process GO:0050794 Regulation of cellular process
Process GO:0050896 Response to stimulus
Process GO:0051052 Regulation of DNA metabolic process
Process GO:0051128 Regulation of cellular component organization
Process GO:0051129 Negative regulation of cellular component organization
Process GO:0051171 Regulation of nitrogen compound metabolic process
Process GO:0051173 Positive regulation of nitrogen compound metabolic process
Process GO:0051174 Regulation of phosphorus metabolic process
Process GO:0051179 Localization
Process GO:0051234 Establishment of localization
Process GO:0051239 Regulation of multicellular organismal process
Process GO:0051246 Regulation of protein metabolic process
Process GO:0051247 Positive regulation of protein metabolic process
Process GO:0051338 Regulation of transferase activity
Process GO:0051347 Positive regulation of transferase activity
Process GO:0051384 Response to glucocorticoid
Process GO:0051493 Regulation of cytoskeleton organization
Process GO:0051494 Negative regulation of cytoskeleton organization
Process GO:0051599 Response to hydrostatic pressure
Process GO:0051716 Cellular response to stimulus
Process GO:0051896 Regulation of protein kinase B signaling
Process GO:0051897 Positive regulation of protein kinase B signaling
Process GO:0055082 Cellular chemical homeostasis
Process GO:0055119 Relaxation of cardiac muscle
Process GO:0060047 Heart contraction
Process GO:0060048 Cardiac muscle contraction
Process GO:0060255 Regulation of macromolecule metabolic process
Process GO:0060548 Negative regulation of cell death
Process GO:0060612 Adipose tissue development
Process GO:0061008 Hepaticobiliary system development
Process GO:0061448 Connective tissue development
Process GO:0062197 Cellular response to chemical stress
Process GO:0065007 Biological regulation
Process GO:0065008 Regulation of biological quality
Process GO:0065009 Regulation of molecular function
Process GO:0070252 Actin-mediated cell contraction
Process GO:0070542 Response to fatty acid
Process GO:0070848 Response to growth factor
Process GO:0070887 Cellular response to chemical stimulus
Process GO:0071214 Cellular response to abiotic stimulus
Process GO:0071229 Cellular response to acid chemical
Process GO:0071310 Cellular response to organic substance
Process GO:0071322 Cellular response to carbohydrate stimulus
Process GO:0071326 Cellular response to monosaccharide stimulus
Process GO:0071331 Cellular response to hexose stimulus
Process GO:0071333 Cellular response to glucose stimulus
Process GO:0071363 Cellular response to growth factor stimulus
Process GO:0071462 Cellular response to water stimulus
Process GO:0071464 Cellular response to hydrostatic pressure
Process GO:0071548 Response to dexamethasone
Process GO:0071704 Organic substance metabolic process
Process GO:0071840 Cellular component organization or biogenesis
Process GO:0072359 Circulatory system development
Process GO:0080090 Regulation of primary metabolic process
Process GO:0086003 Cardiac muscle cell contraction
Process GO:0090066 Regulation of anatomical structure size
Process GO:0090075 Relaxation of muscle
Process GO:0090407 Organophosphate biosynthetic process
Process GO:0097009 Energy homeostasis
Process GO:0104004 Cellular response to environmental stimulus
Process GO:0110053 Regulation of actin filament organization
Process GO:0120261 Regulation of heterochromatin organization
Process GO:1901214 Regulation of neuron death
Process GO:1901215 Negative regulation of neuron death
Process GO:1901576 Organic substance biosynthetic process
Process GO:1901654 Response to ketone
Process GO:1901698 Response to nitrogen compound
Process GO:1901700 Response to oxygen-containing compound
Process GO:1901701 Cellular response to oxygen-containing compound
Process GO:1901879 Regulation of protein depolymerization
Process GO:1901880 Negative regulation of protein depolymerization
Process GO:1902275 Regulation of chromatin organization
Process GO:1902531 Regulation of intracellular signal transduction
Process GO:1902533 Positive regulation of intracellular signal transduction
Process GO:1902903 Regulation of supramolecular fiber organization
Process GO:1902904 Negative regulation of supramolecular fiber organization
Process GO:1903544 Response to butyrate
Process GO:2000209 Regulation of anoikis
Process GO:2000269 Regulation of fibroblast apoptotic process
Process GO:2000270 Negative regulation of fibroblast apoptotic process
Process GO:2000653 Regulation of genetic imprinting
Process GO:2000811 Negative regulation of anoikis
Component GO:0005622 Intracellular anatomical structure
Component GO:0005737 Cytoplasm
Component GO:0005829 Cytosol
Component GO:0005886 Plasma membrane
Component GO:0005911 Cell-cell junction
Component GO:0005942 Phosphatidylinositol 3-kinase complex
Component GO:0005943 Phosphatidylinositol 3-kinase complex, class IA
Component GO:0005944 Phosphatidylinositol 3-kinase complex, class IB
Component GO:0014704 Intercalated disc
Component GO:0016020 Membrane
Component GO:0019898 Extrinsic component of membrane
Component GO:0030027 Lamellipodium
Component GO:0030054 Cell junction
Component GO:0031252 Cell leading edge
Component GO:0032991 Protein-containing complex
Component GO:0042995 Cell projection
Component GO:0044291 Cell-cell contact zone
Component GO:0061695 Transferase complex, transferring phosphorus-containing groups
Component GO:0070161 Anchoring junction
Component GO:0071944 Cell periphery
Component GO:0097651 Phosphatidylinositol 3-kinase complex, class I
Component GO:0098796 Membrane protein complex
Component GO:0110165 Cellular anatomical entity
Component GO:0120025 Plasma membrane bounded cell projection
Component GO:1902494 Catalytic complex
Component GO:1990234 Transferase complex
Function GO:0000166 Nucleotide binding
Function GO:0003824 Catalytic activity
Function GO:0004672 Protein kinase activity
Function GO:0004674 Protein serine/threonine kinase activity
Function GO:0005488 Binding
Function GO:0005515 Protein binding
Function GO:0005524 ATP binding
Function GO:0008047 Enzyme activator activity
Function GO:0016301 Kinase activity
Function GO:0016303 1-phosphatidylinositol-3-kinase activity
Function GO:0016307 Phosphatidylinositol phosphate kinase activity
Function GO:0016740 Transferase activity
Function GO:0016772 Transferase activity, transferring phosphorus-containing groups
Function GO:0016773 Phosphotransferase activity, alcohol group as acceptor
Function GO:0017076 Purine nucleotide binding
Function GO:0019207 Kinase regulator activity
Function GO:0019209 Kinase activator activity
Function GO:0019887 Protein kinase regulator activity
Function GO:0030234 Enzyme regulator activity
Function GO:0030295 Protein kinase activator activity
Function GO:0030554 Adenyl nucleotide binding
Function GO:0032553 Ribonucleotide binding
Function GO:0032555 Purine ribonucleotide binding
Function GO:0032559 Adenyl ribonucleotide binding
Function GO:0035004 Phosphatidylinositol 3-kinase activity
Function GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity
Function GO:0035639 Purine ribonucleoside triphosphate binding
Function GO:0036094 Small molecule binding
Function GO:0043167 Ion binding
Function GO:0043168 Anion binding
Function GO:0043560 Insulin receptor substrate binding
Function GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
Function GO:0052742 Phosphatidylinositol kinase activity
Function GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity
Function GO:0052813 Phosphatidylinositol bisphosphate kinase activity
Function GO:0097159 Organic cyclic compound binding
Function GO:0097367 Carbohydrate derivative binding
Function GO:0098772 Molecular function regulator activity
Function GO:0106310 Protein serine kinase activity
Function GO:0140096 Catalytic activity, acting on a protein
Function GO:1901265 Nucleoside phosphate binding
Function GO:1901363 Heterocyclic compound binding

Pathway annotation


Category Term ID Term description
RCTM RNO-109582 Hemostasis
RCTM RNO-109704 PI3K Cascade
RCTM RNO-112399 IRS-mediated signalling
RCTM RNO-114604 GPVI-mediated activation cascade
RCTM RNO-1227986 Signaling by ERBB2
RCTM RNO-1236394 Signaling by ERBB4
RCTM RNO-1250342 PI3K events in ERBB4 signaling
RCTM RNO-1257604 PIP3 activates AKT signaling
RCTM RNO-1266738 Developmental Biology
RCTM RNO-1280215 Cytokine Signaling in Immune system
RCTM RNO-1280218 Adaptive Immune System
RCTM RNO-1430728 Metabolism
RCTM RNO-1433557 Signaling by SCF-KIT
RCTM RNO-1483255 PI Metabolism
RCTM RNO-1483257 Phospholipid metabolism
RCTM RNO-162582 Signal Transduction
RCTM RNO-1660499 Synthesis of PIPs at the plasma membrane
RCTM RNO-166520 Signaling by NTRKs
RCTM RNO-168249 Innate Immune System
RCTM RNO-168256 Immune System
RCTM RNO-177929 Signaling by EGFR
RCTM RNO-180292 GAB1 signalosome
RCTM RNO-186763 Downstream signal transduction
RCTM RNO-186797 Signaling by PDGF
RCTM RNO-187037 Signaling by NTRK1 (TRKA)
RCTM RNO-190236 Signaling by FGFR
RCTM RNO-194138 Signaling by VEGF
RCTM RNO-194315 Signaling by Rho GTPases
RCTM RNO-1963642 PI3K events in ERBB2 signaling
RCTM RNO-198203 PI3K/AKT activation
RCTM RNO-199418 Negative regulation of the PI3K/AKT network
RCTM RNO-201556 Signaling by ALK
RCTM RNO-202403 TCR signaling
RCTM RNO-202424 Downstream TCR signaling
RCTM RNO-202733 Cell surface interactions at the vascular wall
RCTM RNO-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
RCTM RNO-2029485 Role of phospholipids in phagocytosis
RCTM RNO-210993 Tie2 Signaling
RCTM RNO-2172127 DAP12 interactions
RCTM RNO-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
RCTM RNO-2424491 DAP12 signaling
RCTM RNO-2428924 IGF1R signaling cascade
RCTM RNO-2428928 IRS-related events triggered by IGF1R
RCTM RNO-2454202 Fc epsilon receptor (FCERI) signaling
RCTM RNO-2730905 Role of LAT2/NTAL/LAB on calcium mobilization
RCTM RNO-372790 Signaling by GPCR
RCTM RNO-388396 GPCR downstream signalling
RCTM RNO-388841 Costimulation by the CD28 family
RCTM RNO-389356 CD28 co-stimulation
RCTM RNO-389357 CD28 dependent PI3K/Akt signaling
RCTM RNO-416476 G alpha (q) signalling events
RCTM RNO-422475 Axon guidance
RCTM RNO-4420097 VEGFA-VEGFR2 Pathway
RCTM RNO-449147 Signaling by Interleukins
RCTM RNO-451927 Interleukin-2 family signaling
RCTM RNO-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling
RCTM RNO-556833 Metabolism of lipids
RCTM RNO-5654687 Downstream signaling of activated FGFR1
RCTM RNO-5654689 PI-3K cascade:FGFR1
RCTM RNO-5654695 PI-3K cascade:FGFR2
RCTM RNO-5654696 Downstream signaling of activated FGFR2
RCTM RNO-5654708 Downstream signaling of activated FGFR3
RCTM RNO-5654710 PI-3K cascade:FGFR3
RCTM RNO-5654716 Downstream signaling of activated FGFR4
RCTM RNO-5654720 PI-3K cascade:FGFR4
RCTM RNO-5654736 Signaling by FGFR1
RCTM RNO-5654738 Signaling by FGFR2
RCTM RNO-5654741 Signaling by FGFR3
RCTM RNO-5654743 Signaling by FGFR4
RCTM RNO-5673001 RAF/MAP kinase cascade
RCTM RNO-5683057 MAPK family signaling cascades
RCTM RNO-5684996 MAPK1/MAPK3 signaling
RCTM RNO-6806834 Signaling by MET
RCTM RNO-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
RCTM RNO-74751 Insulin receptor signalling cascade
RCTM RNO-74752 Signaling by Insulin receptor
RCTM RNO-76002 Platelet activation, signaling and aggregation
RCTM RNO-8851907 MET activates PI3K/AKT signaling
RCTM RNO-8853659 RET signaling
RCTM RNO-8939211 ESR-mediated signaling
RCTM RNO-9006335 Signaling by Erythropoietin
RCTM RNO-9006925 Intracellular signaling by second messengers
RCTM RNO-9006931 Signaling by Nuclear Receptors
RCTM RNO-9006934 Signaling by Receptor Tyrosine Kinases
RCTM RNO-9009391 Extra-nuclear estrogen signaling
RCTM RNO-9012999 RHO GTPase cycle
RCTM RNO-9013149 RAC1 GTPase cycle
RCTM RNO-9013404 RAC2 GTPase cycle
RCTM RNO-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
RCTM RNO-912526 Interleukin receptor SHC signaling
RCTM RNO-912631 Regulation of signaling by CBL
RCTM RNO-9607240 FLT3 Signaling
RCTM RNO-9675108 Nervous system development
RCTM RNO-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3
WikiPathways WP1309 Toll-like receptor signaling pathway
WikiPathways WP188 Focal adhesion
WikiPathways WP1968 Genetic alterations of lung cancer
WikiPathways WP2376 Nuclear factor, erythroid-derived 2, like 2 signaling pathway
WikiPathways WP319 IL-3 signaling pathway
WikiPathways WP351 Regulation of actin cytoskeleton
WikiPathways WP376 Renin-angiotensin system
WikiPathways WP569 IL-2 signaling pathway
WikiPathways WP94 Hepatocyte growth factor receptor signaling
RCTM MAP-109582 Hemostasis
RCTM MAP-109704 PI3K Cascade
RCTM MAP-112399 IRS-mediated signalling
RCTM MAP-114604 GPVI-mediated activation cascade
RCTM MAP-1227986 Signaling by ERBB2
RCTM MAP-1236394 Signaling by ERBB4
RCTM MAP-1250342 PI3K events in ERBB4 signaling
RCTM MAP-1257604 PIP3 activates AKT signaling
RCTM MAP-1266738 Developmental Biology
RCTM MAP-1280215 Cytokine Signaling in Immune system
RCTM MAP-1280218 Adaptive Immune System
RCTM MAP-1430728 Metabolism
RCTM MAP-1433557 Signaling by SCF-KIT
RCTM MAP-1483255 PI Metabolism
RCTM MAP-1483257 Phospholipid metabolism
RCTM MAP-162582 Signal Transduction
RCTM MAP-1660499 Synthesis of PIPs at the plasma membrane
RCTM MAP-166520 Signaling by NTRKs
RCTM MAP-168249 Innate Immune System
RCTM MAP-168256 Immune System
RCTM MAP-177929 Signaling by EGFR
RCTM MAP-180292 GAB1 signalosome
RCTM MAP-186763 Downstream signal transduction
RCTM MAP-186797 Signaling by PDGF
RCTM MAP-187037 Signaling by NTRK1 (TRKA)
RCTM MAP-190236 Signaling by FGFR
RCTM MAP-194138 Signaling by VEGF
RCTM MAP-194315 Signaling by Rho GTPases
RCTM MAP-1963642 PI3K events in ERBB2 signaling
RCTM MAP-198203 PI3K/AKT activation
RCTM MAP-199418 Negative regulation of the PI3K/AKT network
RCTM MAP-201556 Signaling by ALK
RCTM MAP-202403 TCR signaling
RCTM MAP-202424 Downstream TCR signaling
RCTM MAP-202733 Cell surface interactions at the vascular wall
RCTM MAP-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
RCTM MAP-2029485 Role of phospholipids in phagocytosis
RCTM MAP-210993 Tie2 Signaling
RCTM MAP-2172127 DAP12 interactions
RCTM MAP-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
RCTM MAP-2424491 DAP12 signaling
RCTM MAP-2428924 IGF1R signaling cascade
RCTM MAP-2428928 IRS-related events triggered by IGF1R
RCTM MAP-2454202 Fc epsilon receptor (FCERI) signaling
RCTM MAP-2730905 Role of LAT2/NTAL/LAB on calcium mobilization
RCTM MAP-372790 Signaling by GPCR
RCTM MAP-388396 GPCR downstream signalling
RCTM MAP-388841 Costimulation by the CD28 family
RCTM MAP-389356 CD28 co-stimulation
RCTM MAP-389357 CD28 dependent PI3K/Akt signaling
RCTM MAP-416476 G alpha (q) signalling events
RCTM MAP-422475 Axon guidance
RCTM MAP-4420097 VEGFA-VEGFR2 Pathway
RCTM MAP-449147 Signaling by Interleukins
RCTM MAP-451927 Interleukin-2 family signaling
RCTM MAP-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling
RCTM MAP-556833 Metabolism of lipids
RCTM MAP-5654687 Downstream signaling of activated FGFR1
RCTM MAP-5654689 PI-3K cascade:FGFR1
RCTM MAP-5654695 PI-3K cascade:FGFR2
RCTM MAP-5654696 Downstream signaling of activated FGFR2
RCTM MAP-5654708 Downstream signaling of activated FGFR3
RCTM MAP-5654710 PI-3K cascade:FGFR3
RCTM MAP-5654716 Downstream signaling of activated FGFR4
RCTM MAP-5654720 PI-3K cascade:FGFR4
RCTM MAP-5654736 Signaling by FGFR1
RCTM MAP-5654738 Signaling by FGFR2
RCTM MAP-5654741 Signaling by FGFR3
RCTM MAP-5654743 Signaling by FGFR4
RCTM MAP-5673001 RAF/MAP kinase cascade
RCTM MAP-5683057 MAPK family signaling cascades
RCTM MAP-5684996 MAPK1/MAPK3 signaling
RCTM MAP-6806834 Signaling by MET
RCTM MAP-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
RCTM MAP-74751 Insulin receptor signalling cascade
RCTM MAP-74752 Signaling by Insulin receptor
RCTM MAP-76002 Platelet activation, signaling and aggregation
RCTM MAP-8851907 MET activates PI3K/AKT signaling
RCTM MAP-8853659 RET signaling
RCTM MAP-8939211 ESR-mediated signaling
RCTM MAP-9006335 Signaling by Erythropoietin
RCTM MAP-9006925 Intracellular signaling by second messengers
RCTM MAP-9006931 Signaling by Nuclear Receptors
RCTM MAP-9006934 Signaling by Receptor Tyrosine Kinases
RCTM MAP-9009391 Extra-nuclear estrogen signaling
RCTM MAP-9012999 RHO GTPase cycle
RCTM MAP-9013149 RAC1 GTPase cycle
RCTM MAP-9013404 RAC2 GTPase cycle
RCTM MAP-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
RCTM MAP-912526 Interleukin receptor SHC signaling
RCTM MAP-912631 Regulation of signaling by CBL
RCTM MAP-9607240 FLT3 Signaling
RCTM MAP-9675108 Nervous system development
RCTM MAP-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3