Gene symbol: SMAD3

Organism: Oryctolagus cuniculus

NCBI gene ID: 100346303


GO Annotation


Category Term ID Term description
Process GO:0000122 Negative regulation of transcription by RNA polymerase II
Process GO:0000165 MAPK cascade
Process GO:0001501 Skeletal system development
Process GO:0001503 Ossification
Process GO:0001558 Regulation of cell growth
Process GO:0001649 Osteoblast differentiation
Process GO:0001654 Eye development
Process GO:0001655 Urogenital system development
Process GO:0001657 Ureteric bud development
Process GO:0001666 Response to hypoxia
Process GO:0001701 In utero embryonic development
Process GO:0001704 Formation of primary germ layer
Process GO:0001707 Mesoderm formation
Process GO:0001756 Somitogenesis
Process GO:0001775 Cell activation
Process GO:0001817 Regulation of cytokine production
Process GO:0001819 Positive regulation of cytokine production
Process GO:0001822 Kidney development
Process GO:0001823 Mesonephros development
Process GO:0001889 Liver development
Process GO:0001947 Heart looping
Process GO:0001952 Regulation of cell-matrix adhesion
Process GO:0001954 Positive regulation of cell-matrix adhesion
Process GO:0002009 Morphogenesis of an epithelium
Process GO:0002076 Osteoblast development
Process GO:0002088 Lens development in camera-type eye
Process GO:0002376 Immune system process
Process GO:0002520 Immune system development
Process GO:0002682 Regulation of immune system process
Process GO:0003002 Regionalization
Process GO:0003007 Heart morphogenesis
Process GO:0003008 System process
Process GO:0003013 Circulatory system process
Process GO:0003143 Embryonic heart tube morphogenesis
Process GO:0006355 Regulation of transcription, DNA-templated
Process GO:0006357 Regulation of transcription by RNA polymerase II
Process GO:0006915 Apoptotic process
Process GO:0006919 Activation of cysteine-type endopeptidase activity involved in apoptotic process
Process GO:0006950 Response to stress
Process GO:0006955 Immune response
Process GO:0007154 Cell communication
Process GO:0007165 Signal transduction
Process GO:0007166 Cell surface receptor signaling pathway
Process GO:0007167 Enzyme-linked receptor protein signaling pathway
Process GO:0007178 Transmembrane receptor protein serine/threonine kinase signaling pathway
Process GO:0007179 Transforming growth factor beta receptor signaling pathway
Process GO:0007183 SMAD protein complex assembly
Process GO:0007254 JNK cascade
Process GO:0007275 Multicellular organism development
Process GO:0007368 Determination of left/right symmetry
Process GO:0007369 Gastrulation
Process GO:0007389 Pattern specification process
Process GO:0007423 Sensory organ development
Process GO:0007440 Foregut morphogenesis
Process GO:0007492 Endoderm development
Process GO:0007498 Mesoderm development
Process GO:0007507 Heart development
Process GO:0008015 Blood circulation
Process GO:0008217 Regulation of blood pressure
Process GO:0008219 Cell death
Process GO:0008285 Negative regulation of cell population proliferation
Process GO:0009605 Response to external stimulus
Process GO:0009607 Response to biotic stimulus
Process GO:0009615 Response to virus
Process GO:0009628 Response to abiotic stimulus
Process GO:0009653 Anatomical structure morphogenesis
Process GO:0009719 Response to endogenous stimulus
Process GO:0009790 Embryo development
Process GO:0009792 Embryo development ending in birth or egg hatching
Process GO:0009799 Specification of symmetry
Process GO:0009855 Determination of bilateral symmetry
Process GO:0009880 Embryonic pattern specification
Process GO:0009887 Animal organ morphogenesis
Process GO:0009888 Tissue development
Process GO:0009889 Regulation of biosynthetic process
Process GO:0009890 Negative regulation of biosynthetic process
Process GO:0009891 Positive regulation of biosynthetic process
Process GO:0009892 Negative regulation of metabolic process
Process GO:0009893 Positive regulation of metabolic process
Process GO:0009894 Regulation of catabolic process
Process GO:0009895 Negative regulation of catabolic process
Process GO:0009952 Anterior/posterior pattern specification
Process GO:0009966 Regulation of signal transduction
Process GO:0009967 Positive regulation of signal transduction
Process GO:0009987 Cellular process
Process GO:0010033 Response to organic substance
Process GO:0010468 Regulation of gene expression
Process GO:0010556 Regulation of macromolecule biosynthetic process
Process GO:0010557 Positive regulation of macromolecule biosynthetic process
Process GO:0010558 Negative regulation of macromolecule biosynthetic process
Process GO:0010562 Positive regulation of phosphorus metabolic process
Process GO:0010604 Positive regulation of macromolecule metabolic process
Process GO:0010605 Negative regulation of macromolecule metabolic process
Process GO:0010611 Regulation of cardiac muscle hypertrophy
Process GO:0010612 Regulation of cardiac muscle adaptation
Process GO:0010614 Negative regulation of cardiac muscle hypertrophy
Process GO:0010616 Negative regulation of cardiac muscle adaptation
Process GO:0010628 Positive regulation of gene expression
Process GO:0010638 Positive regulation of organelle organization
Process GO:0010646 Regulation of cell communication
Process GO:0010647 Positive regulation of cell communication
Process GO:0010692 Regulation of alkaline phosphatase activity
Process GO:0010694 Positive regulation of alkaline phosphatase activity
Process GO:0010717 Regulation of epithelial to mesenchymal transition
Process GO:0010718 Positive regulation of epithelial to mesenchymal transition
Process GO:0010810 Regulation of cell-substrate adhesion
Process GO:0010811 Positive regulation of cell-substrate adhesion
Process GO:0010921 Regulation of phosphatase activity
Process GO:0010922 Positive regulation of phosphatase activity
Process GO:0010941 Regulation of cell death
Process GO:0010950 Positive regulation of endopeptidase activity
Process GO:0010952 Positive regulation of peptidase activity
Process GO:0012501 Programmed cell death
Process GO:0014741 Negative regulation of muscle hypertrophy
Process GO:0014743 Regulation of muscle hypertrophy
Process GO:0014745 Negative regulation of muscle adaptation
Process GO:0014916 Regulation of lung blood pressure
Process GO:0016043 Cellular component organization
Process GO:0016202 Regulation of striated muscle tissue development
Process GO:0017015 Regulation of transforming growth factor beta receptor signaling pathway
Process GO:0019219 Regulation of nucleobase-containing compound metabolic process
Process GO:0019220 Regulation of phosphate metabolic process
Process GO:0019222 Regulation of metabolic process
Process GO:0022607 Cellular component assembly
Process GO:0023019 Signal transduction involved in regulation of gene expression
Process GO:0023051 Regulation of signaling
Process GO:0023052 Signaling
Process GO:0023056 Positive regulation of signaling
Process GO:0030111 Regulation of Wnt signaling pathway
Process GO:0030154 Cell differentiation
Process GO:0030155 Regulation of cell adhesion
Process GO:0030162 Regulation of proteolysis
Process GO:0030177 Positive regulation of Wnt signaling pathway
Process GO:0030278 Regulation of ossification
Process GO:0030308 Negative regulation of cell growth
Process GO:0030325 Adrenal gland development
Process GO:0030334 Regulation of cell migration
Process GO:0030335 Positive regulation of cell migration
Process GO:0030500 Regulation of bone mineralization
Process GO:0030501 Positive regulation of bone mineralization
Process GO:0030509 BMP signaling pathway
Process GO:0030855 Epithelial cell differentiation
Process GO:0030878 Thyroid gland development
Process GO:0031098 Stress-activated protein kinase signaling cascade
Process GO:0031323 Regulation of cellular metabolic process
Process GO:0031324 Negative regulation of cellular metabolic process
Process GO:0031325 Positive regulation of cellular metabolic process
Process GO:0031326 Regulation of cellular biosynthetic process
Process GO:0031327 Negative regulation of cellular biosynthetic process
Process GO:0031328 Positive regulation of cellular biosynthetic process
Process GO:0031347 Regulation of defense response
Process GO:0031348 Negative regulation of defense response
Process GO:0031647 Regulation of protein stability
Process GO:0032101 Regulation of response to external stimulus
Process GO:0032102 Negative regulation of response to external stimulus
Process GO:0032103 Positive regulation of response to external stimulus
Process GO:0032231 Regulation of actin filament bundle assembly
Process GO:0032233 Positive regulation of actin filament bundle assembly
Process GO:0032330 Regulation of chondrocyte differentiation
Process GO:0032332 Positive regulation of chondrocyte differentiation
Process GO:0032501 Multicellular organismal process
Process GO:0032502 Developmental process
Process GO:0032651 Regulation of interleukin-1 beta production
Process GO:0032652 Regulation of interleukin-1 production
Process GO:0032731 Positive regulation of interleukin-1 beta production
Process GO:0032732 Positive regulation of interleukin-1 production
Process GO:0032909 Regulation of transforming growth factor beta2 production
Process GO:0032910 Regulation of transforming growth factor beta3 production
Process GO:0032924 Activin receptor signaling pathway
Process GO:0032956 Regulation of actin cytoskeleton organization
Process GO:0032970 Regulation of actin filament-based process
Process GO:0033043 Regulation of organelle organization
Process GO:0033554 Cellular response to stress
Process GO:0033688 Regulation of osteoblast proliferation
Process GO:0033689 Negative regulation of osteoblast proliferation
Process GO:0034330 Cell junction organization
Process GO:0035050 Embryonic heart tube development
Process GO:0035239 Tube morphogenesis
Process GO:0035270 Endocrine system development
Process GO:0035282 Segmentation
Process GO:0035295 Tube development
Process GO:0035303 Regulation of dephosphorylation
Process GO:0035306 Positive regulation of dephosphorylation
Process GO:0035556 Intracellular signal transduction
Process GO:0036293 Response to decreased oxygen levels
Process GO:0038092 Nodal signaling pathway
Process GO:0040007 Growth
Process GO:0040008 Regulation of growth
Process GO:0040012 Regulation of locomotion
Process GO:0040017 Positive regulation of locomotion
Process GO:0042110 T cell activation
Process GO:0042127 Regulation of cell population proliferation
Process GO:0042176 Regulation of protein catabolic process
Process GO:0042177 Negative regulation of protein catabolic process
Process GO:0042221 Response to chemical
Process GO:0042981 Regulation of apoptotic process
Process GO:0043009 Chordate embryonic development
Process GO:0043010 Camera-type eye development
Process GO:0043066 Negative regulation of apoptotic process
Process GO:0043067 Regulation of programmed cell death
Process GO:0043069 Negative regulation of programmed cell death
Process GO:0043085 Positive regulation of catalytic activity
Process GO:0043207 Response to external biotic stimulus
Process GO:0043280 Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
Process GO:0043281 Regulation of cysteine-type endopeptidase activity involved in apoptotic process
Process GO:0043502 Regulation of muscle adaptation
Process GO:0043933 Protein-containing complex organization
Process GO:0044057 Regulation of system process
Process GO:0044085 Cellular component biogenesis
Process GO:0044087 Regulation of cellular component biogenesis
Process GO:0044089 Positive regulation of cellular component biogenesis
Process GO:0044093 Positive regulation of molecular function
Process GO:0044419 Biological process involved in interspecies interaction between organisms
Process GO:0045216 Cell-cell junction organization
Process GO:0045321 Leukocyte activation
Process GO:0045428 Regulation of nitric oxide biosynthetic process
Process GO:0045429 Positive regulation of nitric oxide biosynthetic process
Process GO:0045595 Regulation of cell differentiation
Process GO:0045596 Negative regulation of cell differentiation
Process GO:0045597 Positive regulation of cell differentiation
Process GO:0045598 Regulation of fat cell differentiation
Process GO:0045599 Negative regulation of fat cell differentiation
Process GO:0045667 Regulation of osteoblast differentiation
Process GO:0045668 Negative regulation of osteoblast differentiation
Process GO:0045778 Positive regulation of ossification
Process GO:0045785 Positive regulation of cell adhesion
Process GO:0045862 Positive regulation of proteolysis
Process GO:0045892 Negative regulation of transcription, DNA-templated
Process GO:0045893 Positive regulation of transcription, DNA-templated
Process GO:0045926 Negative regulation of growth
Process GO:0045934 Negative regulation of nucleobase-containing compound metabolic process
Process GO:0045935 Positive regulation of nucleobase-containing compound metabolic process
Process GO:0045937 Positive regulation of phosphate metabolic process
Process GO:0045944 Positive regulation of transcription by RNA polymerase II
Process GO:0046649 Lymphocyte activation
Process GO:0048332 Mesoderm morphogenesis
Process GO:0048339 Paraxial mesoderm development
Process GO:0048340 Paraxial mesoderm morphogenesis
Process GO:0048468 Cell development
Process GO:0048513 Animal organ development
Process GO:0048518 Positive regulation of biological process
Process GO:0048519 Negative regulation of biological process
Process GO:0048522 Positive regulation of cellular process
Process GO:0048523 Negative regulation of cellular process
Process GO:0048546 Digestive tract morphogenesis
Process GO:0048562 Embryonic organ morphogenesis
Process GO:0048565 Digestive tract development
Process GO:0048568 Embryonic organ development
Process GO:0048583 Regulation of response to stimulus
Process GO:0048584 Positive regulation of response to stimulus
Process GO:0048585 Negative regulation of response to stimulus
Process GO:0048589 Developmental growth
Process GO:0048598 Embryonic morphogenesis
Process GO:0048617 Embryonic foregut morphogenesis
Process GO:0048634 Regulation of muscle organ development
Process GO:0048646 Anatomical structure formation involved in morphogenesis
Process GO:0048701 Embryonic cranial skeleton morphogenesis
Process GO:0048704 Embryonic skeletal system morphogenesis
Process GO:0048705 Skeletal system morphogenesis
Process GO:0048706 Embryonic skeletal system development
Process GO:0048729 Tissue morphogenesis
Process GO:0048731 System development
Process GO:0048732 Gland development
Process GO:0048856 Anatomical structure development
Process GO:0048869 Cellular developmental process
Process GO:0048880 Sensory system development
Process GO:0050678 Regulation of epithelial cell proliferation
Process GO:0050727 Regulation of inflammatory response
Process GO:0050728 Negative regulation of inflammatory response
Process GO:0050776 Regulation of immune response
Process GO:0050789 Regulation of biological process
Process GO:0050790 Regulation of catalytic activity
Process GO:0050793 Regulation of developmental process
Process GO:0050794 Regulation of cellular process
Process GO:0050821 Protein stabilization
Process GO:0050896 Response to stimulus
Process GO:0050920 Regulation of chemotaxis
Process GO:0050921 Positive regulation of chemotaxis
Process GO:0050926 Regulation of positive chemotaxis
Process GO:0050927 Positive regulation of positive chemotaxis
Process GO:0051093 Negative regulation of developmental process
Process GO:0051094 Positive regulation of developmental process
Process GO:0051098 Regulation of binding
Process GO:0051128 Regulation of cellular component organization
Process GO:0051130 Positive regulation of cellular component organization
Process GO:0051171 Regulation of nitrogen compound metabolic process
Process GO:0051172 Negative regulation of nitrogen compound metabolic process
Process GO:0051173 Positive regulation of nitrogen compound metabolic process
Process GO:0051174 Regulation of phosphorus metabolic process
Process GO:0051239 Regulation of multicellular organismal process
Process GO:0051240 Positive regulation of multicellular organismal process
Process GO:0051241 Negative regulation of multicellular organismal process
Process GO:0051246 Regulation of protein metabolic process
Process GO:0051247 Positive regulation of protein metabolic process
Process GO:0051248 Negative regulation of protein metabolic process
Process GO:0051252 Regulation of RNA metabolic process
Process GO:0051253 Negative regulation of RNA metabolic process
Process GO:0051254 Positive regulation of RNA metabolic process
Process GO:0051336 Regulation of hydrolase activity
Process GO:0051345 Positive regulation of hydrolase activity
Process GO:0051403 Stress-activated MAPK cascade
Process GO:0051481 Negative regulation of cytosolic calcium ion concentration
Process GO:0051492 Regulation of stress fiber assembly
Process GO:0051493 Regulation of cytoskeleton organization
Process GO:0051495 Positive regulation of cytoskeleton organization
Process GO:0051496 Positive regulation of stress fiber assembly
Process GO:0051707 Response to other organism
Process GO:0051716 Cellular response to stimulus
Process GO:0051893 Regulation of focal adhesion assembly
Process GO:0051894 Positive regulation of focal adhesion assembly
Process GO:0052547 Regulation of peptidase activity
Process GO:0052548 Regulation of endopeptidase activity
Process GO:0055123 Digestive system development
Process GO:0060039 Pericardium development
Process GO:0060255 Regulation of macromolecule metabolic process
Process GO:0060290 Transdifferentiation
Process GO:0060395 SMAD protein signal transduction
Process GO:0060429 Epithelium development
Process GO:0060485 Mesenchyme development
Process GO:0060548 Negative regulation of cell death
Process GO:0060562 Epithelial tube morphogenesis
Process GO:0060828 Regulation of canonical Wnt signaling pathway
Process GO:0061008 Hepaticobiliary system development
Process GO:0061035 Regulation of cartilage development
Process GO:0061036 Positive regulation of cartilage development
Process GO:0061041 Regulation of wound healing
Process GO:0061045 Negative regulation of wound healing
Process GO:0061053 Somite development
Process GO:0061371 Determination of heart left/right asymmetry
Process GO:0065003 Protein-containing complex assembly
Process GO:0065007 Biological regulation
Process GO:0065008 Regulation of biological quality
Process GO:0065009 Regulation of molecular function
Process GO:0070167 Regulation of biomineral tissue development
Process GO:0070169 Positive regulation of biomineral tissue development
Process GO:0070306 Lens fiber cell differentiation
Process GO:0070482 Response to oxygen levels
Process GO:0070848 Response to growth factor
Process GO:0070887 Cellular response to chemical stimulus
Process GO:0071310 Cellular response to organic substance
Process GO:0071363 Cellular response to growth factor stimulus
Process GO:0071495 Cellular response to endogenous stimulus
Process GO:0071559 Response to transforming growth factor beta
Process GO:0071560 Cellular response to transforming growth factor beta stimulus
Process GO:0071634 Regulation of transforming growth factor beta production
Process GO:0071636 Positive regulation of transforming growth factor beta production
Process GO:0071772 Response to BMP
Process GO:0071773 Cellular response to BMP stimulus
Process GO:0071840 Cellular component organization or biogenesis
Process GO:0072001 Renal system development
Process GO:0072073 Kidney epithelium development
Process GO:0072132 Mesenchyme morphogenesis
Process GO:0072163 Mesonephric epithelium development
Process GO:0072164 Mesonephric tubule development
Process GO:0072359 Circulatory system development
Process GO:0080090 Regulation of primary metabolic process
Process GO:0080134 Regulation of response to stress
Process GO:0080164 Regulation of nitric oxide metabolic process
Process GO:0090092 Regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
Process GO:0090109 Regulation of cell-substrate junction assembly
Process GO:0090257 Regulation of muscle system process
Process GO:0090263 Positive regulation of canonical Wnt signaling pathway
Process GO:0090287 Regulation of cellular response to growth factor stimulus
Process GO:0097190 Apoptotic signaling pathway
Process GO:0097191 Extrinsic apoptotic signaling pathway
Process GO:0097296 Activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Process GO:0098586 Cellular response to virus
Process GO:0110020 Regulation of actomyosin structure organization
Process GO:0110053 Regulation of actin filament organization
Process GO:0110149 Regulation of biomineralization
Process GO:0110151 Positive regulation of biomineralization
Process GO:0150063 Visual system development
Process GO:0150116 Regulation of cell-substrate junction organization
Process GO:0150117 Positive regulation of cell-substrate junction organization
Process GO:1901201 Regulation of extracellular matrix assembly
Process GO:1901203 Positive regulation of extracellular matrix assembly
Process GO:1901861 Regulation of muscle tissue development
Process GO:1901888 Regulation of cell junction assembly
Process GO:1901890 Positive regulation of cell junction assembly
Process GO:1902679 Negative regulation of RNA biosynthetic process
Process GO:1902680 Positive regulation of RNA biosynthetic process
Process GO:1902893 Regulation of miRNA transcription
Process GO:1902895 Positive regulation of miRNA transcription
Process GO:1902903 Regulation of supramolecular fiber organization
Process GO:1902905 Positive regulation of supramolecular fiber organization
Process GO:1903034 Regulation of response to wounding
Process GO:1903035 Negative regulation of response to wounding
Process GO:1903053 Regulation of extracellular matrix organization
Process GO:1903055 Positive regulation of extracellular matrix organization
Process GO:1903242 Regulation of cardiac muscle hypertrophy in response to stress
Process GO:1903243 Negative regulation of cardiac muscle hypertrophy in response to stress
Process GO:1903506 Regulation of nucleic acid-templated transcription
Process GO:1903507 Negative regulation of nucleic acid-templated transcription
Process GO:1903508 Positive regulation of nucleic acid-templated transcription
Process GO:1903844 Regulation of cellular response to transforming growth factor beta stimulus
Process GO:1904407 Positive regulation of nitric oxide metabolic process
Process GO:1904888 Cranial skeletal system development
Process GO:2000026 Regulation of multicellular organismal development
Process GO:2000116 Regulation of cysteine-type endopeptidase activity
Process GO:2000145 Regulation of cell motility
Process GO:2000147 Positive regulation of cell motility
Process GO:2000628 Regulation of miRNA metabolic process
Process GO:2000630 Positive regulation of miRNA metabolic process
Process GO:2001056 Positive regulation of cysteine-type endopeptidase activity
Process GO:2001141 Regulation of RNA biosynthetic process
Process GO:2001267 Regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Process GO:2001269 Positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Process GO:0032916 Positive regulation of transforming growth factor beta3 production
Process GO:0061767 Negative regulation of lung blood pressure
Component GO:0000785 Chromatin
Component GO:0005622 Intracellular anatomical structure
Component GO:0005634 Nucleus
Component GO:0005635 Nuclear envelope
Component GO:0005637 Nuclear inner membrane
Component GO:0005654 Nucleoplasm
Component GO:0005667 Transcription regulator complex
Component GO:0005694 Chromosome
Component GO:0005737 Cytoplasm
Component GO:0005829 Cytosol
Component GO:0005886 Plasma membrane
Component GO:0012505 Endomembrane system
Component GO:0016020 Membrane
Component GO:0019866 Organelle inner membrane
Component GO:0031090 Organelle membrane
Component GO:0031965 Nuclear membrane
Component GO:0031967 Organelle envelope
Component GO:0031974 Membrane-enclosed lumen
Component GO:0031975 Envelope
Component GO:0031981 Nuclear lumen
Component GO:0032991 Protein-containing complex
Component GO:0043226 Organelle
Component GO:0043227 Membrane-bounded organelle
Component GO:0043228 Non-membrane-bounded organelle
Component GO:0043229 Intracellular organelle
Component GO:0043231 Intracellular membrane-bounded organelle
Component GO:0043232 Intracellular non-membrane-bounded organelle
Component GO:0043233 Organelle lumen
Component GO:0043235 Receptor complex
Component GO:0070013 Intracellular organelle lumen
Component GO:0071141 SMAD protein complex
Component GO:0071144 Heteromeric SMAD protein complex
Component GO:0071944 Cell periphery
Component GO:0090575 RNA polymerase II transcription regulator complex
Component GO:0110165 Cellular anatomical entity
Component GO:0140513 Nuclear protein-containing complex
Function GO:0000976 Transcription cis-regulatory region binding
Function GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
Function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
Function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
Function GO:0000987 Cis-regulatory region sequence-specific DNA binding
Function GO:0001067 Transcription regulatory region nucleic acid binding
Function GO:0001216 DNA-binding transcription activator activity
Function GO:0001217 DNA-binding transcription repressor activity
Function GO:0001221 Transcription coregulator binding
Function GO:0001223 Transcription coactivator binding
Function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
Function GO:0003676 Nucleic acid binding
Function GO:0003677 DNA binding
Function GO:0003682 Chromatin binding
Function GO:0003690 Double-stranded DNA binding
Function GO:0003700 DNA-binding transcription factor activity
Function GO:0005102 Signaling receptor binding
Function GO:0005126 Cytokine receptor binding
Function GO:0005160 Transforming growth factor beta receptor binding
Function GO:0005488 Binding
Function GO:0005515 Protein binding
Function GO:0005518 Collagen binding
Function GO:0008013 Beta-catenin binding
Function GO:0008134 Transcription factor binding
Function GO:0008270 Zinc ion binding
Function GO:0016922 Nuclear receptor binding
Function GO:0017151 DEAD/H-box RNA helicase binding
Function GO:0019899 Enzyme binding
Function GO:0019900 Kinase binding
Function GO:0019901 Protein kinase binding
Function GO:0019902 Phosphatase binding
Function GO:0031490 Chromatin DNA binding
Function GO:0031625 Ubiquitin protein ligase binding
Function GO:0032182 Ubiquitin-like protein binding
Function GO:0032810 Sterol response element binding
Function GO:0035259 Nuclear glucocorticoid receptor binding
Function GO:0042802 Identical protein binding
Function GO:0042803 Protein homodimerization activity
Function GO:0043130 Ubiquitin binding
Function GO:0043167 Ion binding
Function GO:0043169 Cation binding
Function GO:0043425 bHLH transcription factor binding
Function GO:0043565 Sequence-specific DNA binding
Function GO:0044389 Ubiquitin-like protein ligase binding
Function GO:0044877 Protein-containing complex binding
Function GO:0046332 SMAD binding
Function GO:0046872 Metal ion binding
Function GO:0046914 Transition metal ion binding
Function GO:0046983 Protein dimerization activity
Function GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding
Function GO:0070410 co-SMAD binding
Function GO:0070411 I-SMAD binding
Function GO:0070412 R-SMAD binding
Function GO:0097159 Organic cyclic compound binding
Function GO:0140110 Transcription regulator activity
Function GO:0140297 DNA-binding transcription factor binding
Function GO:1901363 Heterocyclic compound binding
Function GO:1990837 Sequence-specific double-stranded DNA binding
Function GO:1990841 Promoter-specific chromatin binding
Function GO:0031962 Nuclear mineralocorticoid receptor binding

Pathway annotation


Category Term ID Term description
RCTM MAP-1181150 Signaling by NODAL
RCTM MAP-1266738 Developmental Biology
RCTM MAP-1502540 Signaling by Activin
RCTM MAP-162582 Signal Transduction
RCTM MAP-170834 Signaling by TGF-beta Receptor Complex
RCTM MAP-212436 Generic Transcription Pathway
RCTM MAP-2173788 Downregulation of TGF-beta receptor signaling
RCTM MAP-2173789 TGF-beta receptor signaling activates SMADs
RCTM MAP-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
RCTM MAP-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity
RCTM MAP-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
RCTM MAP-392499 Metabolism of proteins
RCTM MAP-5688426 Deubiquitination
RCTM MAP-5689880 Ub-specific processing proteases
RCTM MAP-597592 Post-translational protein modification
RCTM MAP-73857 RNA Polymerase II Transcription
RCTM MAP-74160 Gene expression (Transcription)
RCTM MAP-8878159 Transcriptional regulation by RUNX3
RCTM MAP-8941855 RUNX3 regulates CDKN1A transcription
RCTM MAP-9006936 Signaling by TGFB family members
RCTM MAP-9614085 FOXO-mediated transcription
RCTM MAP-9617828 FOXO-mediated transcription of cell cycle genes
KEGG ocu04068 FoxO signaling pathway
KEGG ocu04110 Cell cycle
KEGG ocu04144 Endocytosis
KEGG ocu04218 Cellular senescence
KEGG ocu04310 Wnt signaling pathway
KEGG ocu04350 TGF-beta signaling pathway
KEGG ocu04371 Apelin signaling pathway
KEGG ocu04390 Hippo signaling pathway
KEGG ocu04520 Adherens junction
KEGG ocu04550 Signaling pathways regulating pluripotency of stem cells
KEGG ocu04659 Th17 cell differentiation
KEGG ocu04933 AGE-RAGE signaling pathway in diabetic complications
KEGG ocu05161 Hepatitis B
KEGG ocu05166 Human T-cell leukemia virus 1 infection
KEGG ocu05200 Pathways in cancer
KEGG ocu05210 Colorectal cancer
KEGG ocu05212 Pancreatic cancer
KEGG ocu05220 Chronic myeloid leukemia
KEGG ocu05225 Hepatocellular carcinoma
KEGG ocu05226 Gastric cancer
KEGG ocu05321 Inflammatory bowel disease
KEGG ocu05415 Diabetic cardiomyopathy