Gene symbol: GDF2

Organism: Oryctolagus cuniculus

NCBI gene ID: 100351972 Ensembl:ENSOCUG00000013623


GO Annotation


Category Term ID Term description
Process GO:0001503 Ossification
Process GO:0001525 Angiogenesis
Process GO:0001558 Regulation of cell growth
Process GO:0001568 Blood vessel development
Process GO:0001569 Branching involved in blood vessel morphogenesis
Process GO:0001570 Vasculogenesis
Process GO:0001649 Osteoblast differentiation
Process GO:0001763 Morphogenesis of a branching structure
Process GO:0001817 Regulation of cytokine production
Process GO:0001819 Positive regulation of cytokine production
Process GO:0001932 Regulation of protein phosphorylation
Process GO:0001934 Positive regulation of protein phosphorylation
Process GO:0001936 Regulation of endothelial cell proliferation
Process GO:0001937 Negative regulation of endothelial cell proliferation
Process GO:0001938 Positive regulation of endothelial cell proliferation
Process GO:0001944 Vasculature development
Process GO:0002009 Morphogenesis of an epithelium
Process GO:0006139 Nucleobase-containing compound metabolic process
Process GO:0006351 Transcription, DNA-templated
Process GO:0006355 Regulation of transcription, DNA-templated
Process GO:0006357 Regulation of transcription by RNA polymerase II
Process GO:0006366 Transcription by RNA polymerase II
Process GO:0006468 Protein phosphorylation
Process GO:0006725 Cellular aromatic compound metabolic process
Process GO:0006793 Phosphorus metabolic process
Process GO:0006796 Phosphate-containing compound metabolic process
Process GO:0006807 Nitrogen compound metabolic process
Process GO:0006873 Cellular ion homeostasis
Process GO:0006875 Cellular metal ion homeostasis
Process GO:0006879 Cellular iron ion homeostasis
Process GO:0007154 Cell communication
Process GO:0007165 Signal transduction
Process GO:0007166 Cell surface receptor signaling pathway
Process GO:0007167 Enzyme-linked receptor protein signaling pathway
Process GO:0007178 Transmembrane receptor protein serine/threonine kinase signaling pathway
Process GO:0007275 Multicellular organism development
Process GO:0008152 Metabolic process
Process GO:0008284 Positive regulation of cell population proliferation
Process GO:0008285 Negative regulation of cell population proliferation
Process GO:0009058 Biosynthetic process
Process GO:0009059 Macromolecule biosynthetic process
Process GO:0009653 Anatomical structure morphogenesis
Process GO:0009719 Response to endogenous stimulus
Process GO:0009888 Tissue development
Process GO:0009889 Regulation of biosynthetic process
Process GO:0009890 Negative regulation of biosynthetic process
Process GO:0009891 Positive regulation of biosynthetic process
Process GO:0009892 Negative regulation of metabolic process
Process GO:0009893 Positive regulation of metabolic process
Process GO:0009966 Regulation of signal transduction
Process GO:0009967 Positive regulation of signal transduction
Process GO:0009987 Cellular process
Process GO:0010033 Response to organic substance
Process GO:0010467 Gene expression
Process GO:0010468 Regulation of gene expression
Process GO:0010556 Regulation of macromolecule biosynthetic process
Process GO:0010557 Positive regulation of macromolecule biosynthetic process
Process GO:0010558 Negative regulation of macromolecule biosynthetic process
Process GO:0010562 Positive regulation of phosphorus metabolic process
Process GO:0010594 Regulation of endothelial cell migration
Process GO:0010596 Negative regulation of endothelial cell migration
Process GO:0010604 Positive regulation of macromolecule metabolic process
Process GO:0010605 Negative regulation of macromolecule metabolic process
Process GO:0010628 Positive regulation of gene expression
Process GO:0010632 Regulation of epithelial cell migration
Process GO:0010633 Negative regulation of epithelial cell migration
Process GO:0010646 Regulation of cell communication
Process GO:0010647 Positive regulation of cell communication
Process GO:0010862 Positive regulation of pathway-restricted SMAD protein phosphorylation
Process GO:0016070 RNA metabolic process
Process GO:0016310 Phosphorylation
Process GO:0018130 Heterocycle biosynthetic process
Process GO:0019219 Regulation of nucleobase-containing compound metabolic process
Process GO:0019220 Regulation of phosphate metabolic process
Process GO:0019222 Regulation of metabolic process
Process GO:0019438 Aromatic compound biosynthetic process
Process GO:0019538 Protein metabolic process
Process GO:0019725 Cellular homeostasis
Process GO:0022603 Regulation of anatomical structure morphogenesis
Process GO:0023051 Regulation of signaling
Process GO:0023052 Signaling
Process GO:0023056 Positive regulation of signaling
Process GO:0030003 Cellular cation homeostasis
Process GO:0030154 Cell differentiation
Process GO:0030308 Negative regulation of cell growth
Process GO:0030334 Regulation of cell migration
Process GO:0030336 Negative regulation of cell migration
Process GO:0030509 BMP signaling pathway
Process GO:0030510 Regulation of BMP signaling pathway
Process GO:0030513 Positive regulation of BMP signaling pathway
Process GO:0030856 Regulation of epithelial cell differentiation
Process GO:0030858 Positive regulation of epithelial cell differentiation
Process GO:0031323 Regulation of cellular metabolic process
Process GO:0031324 Negative regulation of cellular metabolic process
Process GO:0031325 Positive regulation of cellular metabolic process
Process GO:0031326 Regulation of cellular biosynthetic process
Process GO:0031327 Negative regulation of cellular biosynthetic process
Process GO:0031328 Positive regulation of cellular biosynthetic process
Process GO:0031399 Regulation of protein modification process
Process GO:0031401 Positive regulation of protein modification process
Process GO:0032501 Multicellular organismal process
Process GO:0032502 Developmental process
Process GO:0032677 Regulation of interleukin-8 production
Process GO:0032757 Positive regulation of interleukin-8 production
Process GO:0032774 RNA biosynthetic process
Process GO:0032924 Activin receptor signaling pathway
Process GO:0034641 Cellular nitrogen compound metabolic process
Process GO:0034654 Nucleobase-containing compound biosynthetic process
Process GO:0035239 Tube morphogenesis
Process GO:0035295 Tube development
Process GO:0036211 Protein modification process
Process GO:0040008 Regulation of growth
Process GO:0040012 Regulation of locomotion
Process GO:0040013 Negative regulation of locomotion
Process GO:0042127 Regulation of cell population proliferation
Process GO:0042221 Response to chemical
Process GO:0042325 Regulation of phosphorylation
Process GO:0042327 Positive regulation of phosphorylation
Process GO:0042592 Homeostatic process
Process GO:0043170 Macromolecule metabolic process
Process GO:0043412 Macromolecule modification
Process GO:0044237 Cellular metabolic process
Process GO:0044238 Primary metabolic process
Process GO:0044249 Cellular biosynthetic process
Process GO:0044271 Cellular nitrogen compound biosynthetic process
Process GO:0045595 Regulation of cell differentiation
Process GO:0045597 Positive regulation of cell differentiation
Process GO:0045601 Regulation of endothelial cell differentiation
Process GO:0045603 Positive regulation of endothelial cell differentiation
Process GO:0045765 Regulation of angiogenesis
Process GO:0045766 Positive regulation of angiogenesis
Process GO:0045893 Positive regulation of transcription, DNA-templated
Process GO:0045926 Negative regulation of growth
Process GO:0045934 Negative regulation of nucleobase-containing compound metabolic process
Process GO:0045935 Positive regulation of nucleobase-containing compound metabolic process
Process GO:0045937 Positive regulation of phosphate metabolic process
Process GO:0045944 Positive regulation of transcription by RNA polymerase II
Process GO:0046483 Heterocycle metabolic process
Process GO:0046916 Cellular transition metal ion homeostasis
Process GO:0048514 Blood vessel morphogenesis
Process GO:0048518 Positive regulation of biological process
Process GO:0048519 Negative regulation of biological process
Process GO:0048522 Positive regulation of cellular process
Process GO:0048523 Negative regulation of cellular process
Process GO:0048583 Regulation of response to stimulus
Process GO:0048584 Positive regulation of response to stimulus
Process GO:0048646 Anatomical structure formation involved in morphogenesis
Process GO:0048729 Tissue morphogenesis
Process GO:0048731 System development
Process GO:0048754 Branching morphogenesis of an epithelial tube
Process GO:0048856 Anatomical structure development
Process GO:0048869 Cellular developmental process
Process GO:0048878 Chemical homeostasis
Process GO:0050678 Regulation of epithelial cell proliferation
Process GO:0050679 Positive regulation of epithelial cell proliferation
Process GO:0050680 Negative regulation of epithelial cell proliferation
Process GO:0050789 Regulation of biological process
Process GO:0050793 Regulation of developmental process
Process GO:0050794 Regulation of cellular process
Process GO:0050801 Ion homeostasis
Process GO:0050896 Response to stimulus
Process GO:0051052 Regulation of DNA metabolic process
Process GO:0051053 Negative regulation of DNA metabolic process
Process GO:0051094 Positive regulation of developmental process
Process GO:0051128 Regulation of cellular component organization
Process GO:0051171 Regulation of nitrogen compound metabolic process
Process GO:0051172 Negative regulation of nitrogen compound metabolic process
Process GO:0051173 Positive regulation of nitrogen compound metabolic process
Process GO:0051174 Regulation of phosphorus metabolic process
Process GO:0051239 Regulation of multicellular organismal process
Process GO:0051240 Positive regulation of multicellular organismal process
Process GO:0051241 Negative regulation of multicellular organismal process
Process GO:0051246 Regulation of protein metabolic process
Process GO:0051247 Positive regulation of protein metabolic process
Process GO:0051252 Regulation of RNA metabolic process
Process GO:0051254 Positive regulation of RNA metabolic process
Process GO:0051716 Cellular response to stimulus
Process GO:0055065 Metal ion homeostasis
Process GO:0055072 Iron ion homeostasis
Process GO:0055076 Transition metal ion homeostasis
Process GO:0055080 Cation homeostasis
Process GO:0055082 Cellular chemical homeostasis
Process GO:0060255 Regulation of macromolecule metabolic process
Process GO:0060389 Pathway-restricted SMAD protein phosphorylation
Process GO:0060393 Regulation of pathway-restricted SMAD protein phosphorylation
Process GO:0060395 SMAD protein signal transduction
Process GO:0060429 Epithelium development
Process GO:0060562 Epithelial tube morphogenesis
Process GO:0061035 Regulation of cartilage development
Process GO:0061036 Positive regulation of cartilage development
Process GO:0061138 Morphogenesis of a branching epithelium
Process GO:0065007 Biological regulation
Process GO:0065008 Regulation of biological quality
Process GO:0070848 Response to growth factor
Process GO:0070887 Cellular response to chemical stimulus
Process GO:0071310 Cellular response to organic substance
Process GO:0071363 Cellular response to growth factor stimulus
Process GO:0071495 Cellular response to endogenous stimulus
Process GO:0071704 Organic substance metabolic process
Process GO:0071772 Response to BMP
Process GO:0071773 Cellular response to BMP stimulus
Process GO:0072359 Circulatory system development
Process GO:0080090 Regulation of primary metabolic process
Process GO:0090092 Regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
Process GO:0090100 Positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
Process GO:0090287 Regulation of cellular response to growth factor stimulus
Process GO:0090304 Nucleic acid metabolic process
Process GO:0097659 Nucleic acid-templated transcription
Process GO:0098771 Inorganic ion homeostasis
Process GO:1901342 Regulation of vasculature development
Process GO:1901360 Organic cyclic compound metabolic process
Process GO:1901362 Organic cyclic compound biosynthetic process
Process GO:1901564 Organonitrogen compound metabolic process
Process GO:1901576 Organic substance biosynthetic process
Process GO:1902680 Positive regulation of RNA biosynthetic process
Process GO:1903506 Regulation of nucleic acid-templated transcription
Process GO:1903508 Positive regulation of nucleic acid-templated transcription
Process GO:1904018 Positive regulation of vasculature development
Process GO:2000026 Regulation of multicellular organismal development
Process GO:2000145 Regulation of cell motility
Process GO:2000146 Negative regulation of cell motility
Process GO:2000278 Regulation of DNA biosynthetic process
Process GO:2000279 Negative regulation of DNA biosynthetic process
Process GO:2001141 Regulation of RNA biosynthetic process
Component GO:0005576 Extracellular region
Component GO:0005615 Extracellular space
Component GO:0110165 Cellular anatomical entity
Function GO:0005102 Signaling receptor binding
Function GO:0005125 Cytokine activity
Function GO:0005488 Binding
Function GO:0005515 Protein binding
Function GO:0008083 Growth factor activity
Function GO:0030545 Signaling receptor regulator activity
Function GO:0030546 Signaling receptor activator activity
Function GO:0048018 Receptor ligand activity
Function GO:0098772 Molecular function regulator activity

Pathway annotation


Category Term ID Term description
RCTM MAP-162582 Signal Transduction
RCTM MAP-201451 Signaling by BMP
RCTM MAP-9006936 Signaling by TGFB family members