- The advantages of acupuncture anesthesia in clinical practice
In clinical practice, acupuncture anesthesia presents a multitude of advantages, pivotal among these being Body System Protection. This technique supports the body's natural defenses, reducing the physiological stress often associated with surgical procedures. By modulating the body's response to pain, acupuncture anesthesia allows for a lower Dosage of Medication, significantly reducing the potential for drug-related side effects. Furthermore, this approach plays a crucial role in Emotion Regulation, helping patients maintain a calm and stable emotional state, which is essential for a positive surgical outcome. The impact of acupuncture on the nervous system not only aids in Pain Relief but also promotes Enhanced Recovery After Surgery. Patients tend to experience faster recuperation times, attributed to the holistic nature of this method. Additionally, acupuncture anesthesia is associated with a Lower Incidence of Side Effects compared to conventional anesthetics. Its ability to modulate and balance the body's responses makes it an invaluable tool in the realm of modern medicine, offering a safer, more patient-centered approach to pain management and recovery.
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Modulation
- Immunity
- Acupuncture anesthesia may enhance the body's immune response, reducing the risk of postoperative infections.
- Blood Flow
- Acupuncture anesthesia can optimize blood flow to tissues, aiding in wound healing and tissue recovery.
- Endocrinology
- Acupuncture anesthesia can influence endocrine function, helping maintain hormonal balance during surgery.
- Circulation
- Acupuncture anesthesia supports overall circulatory health, ensuring adequate oxygen and nutrient delivery to tissues.
- Microcirculation
- Acupuncture anesthesia positively affects microcirculation, benefiting tissue perfusion and healing.
- Blood Pressure
- Acupuncture anesthesia can help stabilize blood pressure, reducing perioperative hypertension risks.
- Heart Rate
- Acupuncture anesthesia can regulate heart rate, promoting cardiovascular stability during surgery.
- Hemodynamics
- Acupuncture anesthesia optimizes hemodynamic parameters, contributing to surgical safety.
- Bleeding
- Acupuncture anesthesia may reduce intraoperative bleeding, enhancing surgical outcomes.
- Skin Temperature
- Acupuncture anesthesia can help maintain stable skin temperature during surgery, preventing hypothermia.
Acupuncture anesthesia for Modulation-Blood Pressure
| PMID | Evidence | Source | Keyword | Type |
|---|---|---|---|---|
| 17663116 | Survey of studies on mechanisms of acupuncture and moxibustion in decreasing blood pressure. | Zhongguo Zhen Jiu. 2007 Jun;27(6):467-70. | Blood Pressure | Review |
| 17663116 | The present paper reviews the studies on nervous regulation, humoral regulation and regulation of peripheral vessel resistance and other pathways and their relationships in recent ten years, and indicates further perfecting these studies from the following aspects: studies on the mechanism of section and combination of blood pressure-decreasing points, relationship of time-effect and dose-effect of acupuncture and moxibustion, and studies on mechanisms of functions of nerve-endocrine-immune system. | Zhongguo Zhen Jiu. 2007 Jun;27(6):467-70. | Immunity Endocrinology Blood Pressure | Review |
| 18807728 | Progress in the research of neuroendocrine-immunological mechanism of acupuncture in regulating blood pressure and protecting target organs in hypertension. | Zhen Ci Yan Jiu. 2008 Jun;33(3):208-12. | Immunity Blood Pressure | Review |
| 18807728 | By ways of favorable bi-directionally-regulative effect of acupoint stimulation and close correlation between acupoints and Zangfu-organs, acupuncture therapy can effectively regulate both blood pressure and functional activities of the corresponding viscera. | Zhen Ci Yan Jiu. 2008 Jun;33(3):208-12. | Blood Pressure | Review |
| 19008863 | Acupuncture for lowering blood pressure: systematic review and meta-analysis. | Am J Hypertens. 2009 Jan;22(1):122-8. doi: 10.1038/ajh.2008.311. Epub 2008 Nov 13. | Blood Pressure | Review |
| 19008863 | BACKGROUND: We conducted a systematic review to estimate the effect of acupuncture on blood pressure (BP) in hypertensive patients. | Am J Hypertens. 2009 Jan;22(1):122-8. doi: 10.1038/ajh.2008.311. Epub 2008 Nov 13. | Blood Pressure | Review |
| 19008863 | Three sham-controlled trials out of 11 studies were statistically pooled: systolic BP (SBP) change was not statistically significant (mean difference -5 mm Hg, 95% CI (-12, 1), P = 0.12) and acupuncture only marginally reduced diastolic BP (DBP) by 3 mm Hg (95% CI (-6, 0), P = 0.05), but substantial heterogeneity was observed (I(2) = 92% for SBP, I(2) = 79% for DBP). | Am J Hypertens. 2009 Jan;22(1):122-8. doi: 10.1038/ajh.2008.311. Epub 2008 Nov 13. | Blood Pressure | Review |
| 19008863 | Four studies that investigated acupuncture against antihypertensive medication indicated noninferiority of acupuncture in lowering BP, albeit the quality of them was poor, and their sample sizes were not satisfactory as an equivalence study. | Am J Hypertens. 2009 Jan;22(1):122-8. doi: 10.1038/ajh.2008.311. Epub 2008 Nov 13. | Blood Pressure | Review |
| 19008863 | CONCLUSIONS: Considering the limitation of the four positive noninferiority studies and the results of the meta-analysis of the three sham-controlled studies, the notion that acupuncture may lower high BP is inconclusive. | Am J Hypertens. 2009 Jan;22(1):122-8. doi: 10.1038/ajh.2008.311. Epub 2008 Nov 13. | Blood Pressure | Review |
| 20232615 | Acupuncture arms achieved significant effect modification on blood pressure compared with control arms (19 comparisons: systolic blood pressure [SBP]: mean difference -4.23 mmHg, 95% confidence intervals -6.47 to -1.99; diastolic blood pressure [DBP]: -2.53, -3.99 to -1.08), with significant heterogeneity. | Altern Ther Health Med. 2010 Mar-Apr;16(2):18-29. | Blood Pressure | Review |
| 20232615 | In high-quality trials, blood pressure was significantly lower in treatments of acupuncture plus antihypertensive drug arms than in sham-acupuncture plus hypertensive drug arms (two comparisons: SBP: -5.72 mmHg, -8.77 to -2.68; DBP: -2.80, -5.07 to -0.54), with no significant heterogeneity. | Altern Ther Health Med. 2010 Mar-Apr;16(2):18-29. | Blood Pressure | Review |
| 20232615 | As for trials using prescription adhering to the principles of syndrome differentiation, we found a significant blood pressure reduction with acupuncture arms in comparison with control arms (11 comparisons: SBP: -6.46 mmHg, -8.04 to -4.87; DBP: -3.07, -4.17 to -1.96) with no significant heterogeneity. | Altern Ther Health Med. 2010 Mar-Apr;16(2):18-29. | Blood Pressure | Review |
| 20232615 | In contrast, in trials not using prescription adhering to the principles of syndrome differentiation, we found no significant reduction in blood pressure with acupuncture arms in comparison with control arms (eight comparisons: SBP: -1.55 mmHg, -5.39 to 2.29; DBP: -2.12, -4.97 to 0.73) with significant heterogeneity. | Altern Ther Health Med. 2010 Mar-Apr;16(2):18-29. | Blood Pressure | Review |
| 20399151 | In addition to the analgesic effect of acupuncture, an increasing number of studies have demonstrated that acupuncture treatment can control autonomic nerve system functions such as blood pressure regulation, sphincter Oddi relaxation, and immune modulation. | Auton Neurosci. 2010 Oct 28;157(1-2):38-41. doi: 10.1016/j.autneu.2010.03.010. Epub 2010 Apr 15. | Analgesic Effect Immunity Blood Pressure | Review |
| 20626152 | For this reason, the authors hold that the coming researches on acupuncture therapy for cardiovascular disorders should pay more attention to its clinical application, for example, controlled blood-pressure decline induced lower perfusion of the coronary artery, cardiac surgery (percutaneous tranluminal coronary angioplasty, intracardiac operation underdirect vision) etc. | Zhen Ci Yan Jiu. 2010 Apr;35(2):156-60. | Cardiovascular Blood Pressure | Review |
| 22967279 | One of these trials noted that electroacupuncture stimulation of either PC 5 and PC 6 or LU 7 and LI4 significantly increased peak power output, blood pressure, and rate pressure product (RPP) versus control. | J Altern Complement Med. 2013 Jan;19(1):9-16. doi: 10.1089/acm.2011.0727. Epub 2012 Sep 11. | Blood Pressure | Review |
| 24215927 | Acupuncture regulation of blood pressure: two decades of research. | Int Rev Neurobiol. 2013;111:257-71. doi: 10.1016/B978-0-12-411545-3.00013-4. | Blood Pressure | Review |
| 24215927 | In the last two decades, our laboratory has systematically investigated the peripheral and central neural mechanisms underlying acupuncture regulation of blood pressure. | Int Rev Neurobiol. 2013;111:257-71. doi: 10.1016/B978-0-12-411545-3.00013-4. | Blood Pressure | Review |
| 24215927 | Second, variable regions in the supraspinal and spinal central nervous system that receive input from somatic afferent stimulation account for acupuncture's ability to modulate blood pressure. | Int Rev Neurobiol. 2013;111:257-71. doi: 10.1016/B978-0-12-411545-3.00013-4. | Blood Pressure | Review |
| 24215927 | Thus, depending on the underlying situation, for example, high or low blood pressure, acupuncture modifies autonomic outflow by reducing activity in brain stem nuclei that participate in the primary response. | Int Rev Neurobiol. 2013;111:257-71. doi: 10.1016/B978-0-12-411545-3.00013-4. | Blood Pressure | Review |
| 25219132 | In the present paper, the authors introduce 1) progress of researches on the pathogenesis of hypertension from cellular immune and body fluid immune (multiple immuno-humoral factors); 2) effects of acupuncture intervention on natural killer cell activity, exercise-induced immunosuppression, circulating inflammatory factor levels and balance of cytokines; 3) blood-pressure reduction effect of acupuncture intervention by lowering circulating TNF-alpha, IL-6, matrix metalloproteinases-9, angiotensin convertase and endothelin levels, and up-regulating serum opioid peptide content, etc. | Zhen Ci Yan Jiu. 2014 Aug;39(4):333-6. | Immunity Blood Pressure Circulation | Review |
| 2568074 | Beneficial effects of external Qi Gong treatment given by a Qi Gong practitioner 1 to 3 times for 10-20 seconds each (although most Qi Gong masters take 3-20 minutes per treatment) often resulted in improvement of circulation and lowering of high blood pressure, as well as relaxation of spastic muscles, relief of pain, and enhanced general well-being, all of which resemble acupuncture effects. | Acupunct Electrother Res. 1989;14(1):61-89. doi: 10.3727/036012989816358506. | Pain Relief Blood Pressure Circulation | Review |
| 27924797 | Acupuncture for Blood Pressure Control in Stroke Patients: Case Reports. | Forsch Komplementmed. 2016;23(6):351-355. doi: 10.1159/000452984. Epub 2016 Dec 8. | Blood Pressure | Review |
| 27924797 | The blood pressure-lowering effect of acupuncture alone is controversial but worthy of exploration, considering the side effects of and the problems of low adherence to drugs. | Forsch Komplementmed. 2016;23(6):351-355. doi: 10.1159/000452984. Epub 2016 Dec 8. | Side Effects Blood Pressure | Review |
| 27924797 | Our acupuncture treatment of 40 sessions alone regulated his blood pressure to about 110/70-130/80 mm Hg, with disappearance of the dizziness after 3 sessions. | Forsch Komplementmed. 2016;23(6):351-355. doi: 10.1159/000452984. Epub 2016 Dec 8. | Blood Pressure | Review |
| 27924797 | The second male patient with a suboptimal blood pressure during treatment with 50 mg/day of irbesartan received sole acupuncture treatment of 41 sessions, which decreased his blood pressure to about 120/70-130/80 mm Hg after 6 sessions. | Forsch Komplementmed. 2016;23(6):351-355. doi: 10.1159/000452984. Epub 2016 Dec 8. | Blood Pressure | Review |
| 27924797 | The third patient, who refused to take antihypertensive drugs because of their side effects, received acupuncture treatment of 46 sessions over 2 months, which reduced his blood pressure from 150/90 to 120/80 mm Hg. | Forsch Komplementmed. 2016;23(6):351-355. doi: 10.1159/000452984. Epub 2016 Dec 8. | Side Effects Blood Pressure | Review |
| 27924797 | CONCLUSION: Our cases suggest the potential of acupuncture alone to favorably control high blood pressure or regulate low blood pressure in stroke individuals, as a means of secondary prevention of stroke. | Forsch Komplementmed. 2016;23(6):351-355. doi: 10.1159/000452984. Epub 2016 Dec 8. | Blood Pressure | Review |
| 29393105 | Still, the potential of acupuncture in regulating the blood pressure for secondary stroke prevention deserves our focus. | Complement Med Res. 2018;25(1):45-51. doi: 10.1159/000475930. Epub 2018 Jan 23. | Blood Pressure | Review |
| 3049394 | The blood pressure and heart rate stability that have been observed with acupuncture analgesia have not been sufficiently explained and warrant further investigation, as does the possibility that acupuncture may be helpful in shock states characterized by increased stress hormone concentrations. | Int Anesthesiol Clin. 1988 Fall;26(3):213-7. doi: 10.1097/00004311-198802630-00007. | Heart Rate Blood Pressure | Review |
| 30670261 | Should acupuncture, biofeedback, massage, Qi gong, relaxation therapy, device-guided breathing, yoga and tai chi be used to reduce blood pressure?: Recommendations based on high-quality systematic reviews. | Complement Ther Med. 2019 Feb;42:322-331. doi: 10.1016/j.ctim.2018.10.017. Epub 2018 Oct 26. | Blood Pressure | Review |
| 30670261 | Based on the analyzed evidence, massage and acupuncture plus antihypertensive drug could benefit people who want to lower their BP and do not have contraindications for massage and acupuncture plus antihypertensive drug. | Complement Ther Med. 2019 Feb;42:322-331. doi: 10.1016/j.ctim.2018.10.017. Epub 2018 Oct 26. | Blood Pressure | Review |
| 30712726 | Acupuncture combined with Western medicine (WM) was superior to WM in systolic blood pressure (SBP) and diastolic blood pressure (DBP), efficacy rate, and traditional Chinese medicine (TCM) syndrome. | Complement Ther Clin Pract. 2019 Feb;34:185-194. doi: 10.1016/j.ctcp.2018.12.003. Epub 2018 Dec 7. | Blood Pressure | Review |
| 31383426 | Our results also show acupuncture can improve blood lipids and blood pressure control, and reduce weight. | Complement Ther Clin Pract. 2019 Aug;36:100-112. doi: 10.1016/j.ctcp.2019.04.004. Epub 2019 Jul 2. | Blood Pressure | Review |
| 32744860 | Acupuncture for Regulating Blood Pressure of Stroke Patients: A Systematic Review and Meta-Analysis. | J Altern Complement Med. 2020 Dec;26(12):1105-1116. doi: 10.1089/acm.2019.0454. Epub 2020 Jul 31. | Blood Pressure | Review |
| 32744860 | Previous studies have reported that acupuncture may be effective in lowering BP in patients with hypertension. | J Altern Complement Med. 2020 Dec;26(12):1105-1116. doi: 10.1089/acm.2019.0454. Epub 2020 Jul 31. | Blood Pressure | Review |
| 32744860 | Objectives: This study was aimed at evaluating the efficacy of acupuncture in regulating BP in stroke patients, including both cerebral infarction and hemorrhage. | J Altern Complement Med. 2020 Dec;26(12):1105-1116. doi: 10.1089/acm.2019.0454. Epub 2020 Jul 31. | Bleeding Blood Pressure | Review |
| 32744860 | Only randomized controlled trials that evaluated the efficacy of acupuncture for stroke patients were included and meta-analyzed, and BP data and risk of bias were extracted by scanning the full texts. | J Altern Complement Med. 2020 Dec;26(12):1105-1116. doi: 10.1089/acm.2019.0454. Epub 2020 Jul 31. | Blood Pressure | Review |
| 32744860 | Two trials reported that BP was lowered more in the group who had received acupuncture treatment than the group who were treated with conventional medication. | J Altern Complement Med. 2020 Dec;26(12):1105-1116. doi: 10.1089/acm.2019.0454. Epub 2020 Jul 31. | Blood Pressure | Review |
| 32744860 | Two trials reported that BP was lowered after auricular acupuncture treatment more than those observed in the group receiving conventional medical treatment. | J Altern Complement Med. 2020 Dec;26(12):1105-1116. doi: 10.1089/acm.2019.0454. Epub 2020 Jul 31. | Blood Pressure | Review |
| 32744860 | Conclusions: It was concluded that acupuncture may be a suitable treatment option for regulating BP after stroke. | J Altern Complement Med. 2020 Dec;26(12):1105-1116. doi: 10.1089/acm.2019.0454. Epub 2020 Jul 31. | Blood Pressure | Review |
| 3301357 | Recent studies suggest that physical activity, as well as electric nerve stimulation and acupuncture, sends specific afferent nerve signals to the central nervous system resulting afterwards in increased pain threshold, and lower activity in the central sympathetic nervous system, resulting in lower heart rate and blood pressure. | Eur Heart J. 1987 May;8 Suppl B:71-6. doi: 10.1093/eurheartj/8.suppl_b.71. | Heart Rate Blood Pressure | Review |
| 33706064 | TCM managements for EH-SF52 includes Chinese herbal medication, acupuncture, qigong, taichi, massage, food therapy, as well as lifestyle changes, which targets symptomatic alleviation and blood pressure reduction in a multi-mechanistic manner. | Complement Ther Clin Pract. 2021 May;43:101354. doi: 10.1016/j.ctcp.2021.101354. Epub 2021 Mar 6. | Blood Pressure | Review |
| 35963138 | BACKGROUND: Acupuncture is a traditional therapy that can be potentially effective for treating high blood pressure. | Complement Ther Clin Pract. 2022 Nov;49:101649. doi: 10.1016/j.ctcp.2022.101649. Epub 2022 Aug 7. | Blood Pressure | Review |
| 35963138 | The primary outcomes were changes in blood pressure after acupuncture and efficacy of acupuncture. | Complement Ther Clin Pract. 2022 Nov;49:101649. doi: 10.1016/j.ctcp.2022.101649. Epub 2022 Aug 7. | Blood Pressure | Review |
| 35963138 | Our meta-analysis demonstrated that in terms of changes in systolic blood pressure (MD 3.62 mmHg; 95% CI, 1.34 to 5.90; I(2) = 56%), diastolic blood pressure (MD 3.12 mmHg; 95% CI, 1.03 to 5.20; I(2) = 77%), and treatment efficacy (RR 2.12; 95% CI, 1.38 to 3.26; I(2) = 93%), acupuncture is more effective in treating grade 1 hypertension than a placebo, no treatment at all, or interventions that improve lifestyle alone, with a low incidence of adverse effects. | Complement Ther Clin Pract. 2022 Nov;49:101649. doi: 10.1016/j.ctcp.2022.101649. Epub 2022 Aug 7. | Adverse Reactions Blood Pressure | Review |
| 16824230 | In addition, studies have shown that acupuncture may alter brain chemistry by changing the release of neurotransmitters and neurohormones and, thus, affecting the parts of the central nervous system related to sensation and involuntary body functions, such as immune reactions and processes that regulate a person's blood pressure, blood flow, and body temperature"". | BMC Complement Altern Med. 2006 Jul 7;6:25. doi: 10.1186/1472-6882-6-25. | Immunity Blood Pressure Blood Flow | Review |
| 16824230 | This rationale was also used to explain the effects of acupuncture on nausea/vomiting, obesity, Parkinson's, irritable bowel, immune function, lower esophageal sphincter relaxations, blood pressure, post-menopausal vasomotor symptoms, colitis and sleep quality. | BMC Complement Altern Med. 2006 Jul 7;6:25. doi: 10.1186/1472-6882-6-25. | Immunity Nausea and Vomiting Blood Pressure Sleep Quality | Review |
| 16824230 | However, there were positive findings in 17 of 18 studies (94%) whose outcome of interest measured specific physiologic changes (brain blood flow using fMRI imaging, muscle blood flow, morphologic changes in sperm structure, association of acupuncture response to genotype, effect on leukocyte circulation, heart rate or heart rate variability, blood pressure, sweat rate, tissue impedance, sensations of skin piercing, post-menopausal vasomotor symptoms or ultrasound imaging of tissue morphology.) | BMC Complement Altern Med. 2006 Jul 7;6:25. doi: 10.1186/1472-6882-6-25. | Heart Rate Blood Pressure Circulation Blood Flow | Review |
| 20602794 | For example, moxibustion given at the acupuncture point of GV26 during halothane anesthesia in non-hypertensive dogs resulted in an increase in arterial BP with a decrease in peripheral resistance. | BMC Cardiovasc Disord. 2010 Jul 5;10:33. doi: 10.1186/1471-2261-10-33. | Blood Pressure | Review |
| 22378585 | An investigation of the blood pressure and associated changes in human heart rate variability by manual stimulation of the PC6 indicated that the autonomic innervations of the heart are modified by acupuncture. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Heart Rate Blood Pressure | Review |
| 24073009 | The involvement of endogenous opioids within the central nervous system has been suggested to mediate the effect of acupuncture-induced analgesia and lowering of blood pressure. | Evid Based Complement Alternat Med. 2013;2013:762615. doi: 10.1155/2013/762615. Epub 2013 Sep 2. | Blood Pressure | Review |
| 24073009 | Further implications of acupuncture involving modulation of autonomic function are the reducing effect on MSNA and blood pressure. | Evid Based Complement Alternat Med. 2013;2013:762615. doi: 10.1155/2013/762615. Epub 2013 Sep 2. | Blood Pressure | Review |
| 24073009 | The pain reliving effect of acupuncture was further blocked by low doses of naloxone, an opioid receptor antagonist, and the blood pressure suppression by high doses of naloxone. | Evid Based Complement Alternat Med. 2013;2013:762615. doi: 10.1155/2013/762615. Epub 2013 Sep 2. | Blood Pressure | Review |
| 24523823 | found that although short-term acupuncture did not significantly decrease blood pressure, it appeared to decrease body pain and improve vitality. | Evid Based Complement Alternat Med. 2014;2014:568429. doi: 10.1155/2014/568429. Epub 2014 Jan 2. | Blood Pressure | Review |
| 24723957 | Our results are consistent with acupuncture significantly lowers blood pressure in patients taking antihypertensive medications. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Blood Pressure | Review |
| 24723957 | We did not find that acupuncture without antihypertensive medications significantly improves blood pressure in those hypertensive patients. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Blood Pressure | Review |
| 24723957 | The efficacy of acupuncture for lowering BP was suggested by many published case reports and uncontrolled trials that have shown significant associated reductions. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Blood Pressure | Review |
| 24723957 | Exclusion criteria included the following: (1) nonrandomized studies; (2) studies involving other forms of acupuncture, such as transcutaneous electrical nerve stimulation or laser acupuncture; (3) duplicate reporting with same results; (4) a lack of follow-up outcome data about BP; (5) if controls were given complementary or alternative therapies of which the efficacy is not yet established (e.g., herbal medicine). | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Blood Pressure | Review |
| 24723957 | Following data were extracted independently by two of the authors (D. Li and Y. Zhou): (1) details of participants (e.g., gender, age, hypertension grade, and risk factors); (2) trial design, sample size, blinding, intervention procedures, withdrawals, and dropouts; (3) net changes in SBP and DBP and/or mean BP before and after acupuncture treatment as available. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Blood Pressure | Review |
| 24723957 | All studies used sham acupuncture: 1 trial used superficial acupuncture in the control procedure; 2 used nonpenetrating acupuncture on either nonacupuncture points or real acupuncture points; and 1 used penetrating acupuncture on points irrelevant for lowering BP. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Blood Pressure | Review |
| 24723957 | As early as the 1950s, results from many clinical studies have suggested beneficial effects of acupuncture for lowering BP in patients with essential hypertension. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Blood Pressure | Review |
| 24723957 | Results from many studies in China have suggested that acupuncture was a good adjunctive therapy for treating hypertension, but the drawn conclusions were not credible because these studies were all either observational or case reports with small sample sizes, unrigorous designs, and control group interventions being medications or other BP lowering therapies. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Blood Pressure | Review |
| 24723957 | In recent years, 4 high-quality studies about acupuncture for lowering BP were published, 2 of which suggested that acupuncture lowered mean BP compared to sham acupuncture, while the remaining 2 showed a no significant effect of acupuncture. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Blood Pressure | Review |
| 24723957 | In our meta-analysis, we found that acupuncture was able to lower DBP only and to help antihypertensive medications to lower BP. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Blood Pressure | Review |
| 24723957 | Our study provided evidence that acupuncture helped (lowered) BP in patients taking antihypertensive medications but had no effect for the patients without antihypertensive medications. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Blood Pressure | Review |
| 24723957 | The duration and frequency of acupuncture treatment are not enough so that only acupuncture could not lower blood pressure. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Blood Pressure | Review |
| 24723957 | 's study proved that short-term (one month) acupuncture did not decrease BP significantly and acupuncture may regulate the cardiovascular system through a complicated brain network from the cortical level, the hypothalamus, and the brainstem. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Cardiovascular Blood Pressure | Review |
| 24723957 | Yin and Du found that acupuncture (3 months) can decrease the immediate BP, lower more blood pressure with the time of acupuncture treatment going, and maintain the antihypertensive effect for primary hypertension. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Blood Pressure | Review |
| 24723957 | found that acupuncture (5 times weekly, 12 weeks) had an effect on reducing BP, especially in synergy with medication. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Blood Pressure | Review |
| 24723957 | Results from this meta-analysis of randomized sham-controlled trials provide evidence that acupuncture helped (lowered) BP in patients taking antihypertensive medications. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Blood Pressure | Review |
| 24723957 | Our results did not provide support that acupuncture alone significantly lowers BP in patients with hypertension. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Blood Pressure | Review |
| 25097658 | Emerging evidences indicate that acupuncture could regulate blood pressure in hypertensive patients. | Evid Based Complement Alternat Med. 2014;2014:483294. doi: 10.1155/2014/483294. Epub 2014 Jul 7. | Blood Pressure | Review |
| 25097658 | Acupuncture could decrease blood pressure by increasing antioxidant enzymes, such as glutamate dehydrogenase 1, aldehyde dehydrogenase 2, glutathione S-transferase M5, and SOD in the medulla of the SHRs. | Evid Based Complement Alternat Med. 2014;2014:483294. doi: 10.1155/2014/483294. Epub 2014 Jul 7. | Blood Pressure | Review |
| 25097658 | These views suggest that antihypertensive effects of acupuncture may be mediated by antioxidant enzymes and anti-inflammatory effects, which could modulate the renal sympathetic nerve activity and nitric oxide levels, leading to decreased blood pressure. | Evid Based Complement Alternat Med. 2014;2014:483294. doi: 10.1155/2014/483294. Epub 2014 Jul 7. | Blood Pressure Kidney | Review |
| 26207806 | Compared with sham acupuncture plus medication, a meta-analysis of 2 trials revealed that acupuncture as an adjunct to medication was more effective on systolic (SBP) and diastolic (DBP) blood pressure change magnitude (n=170, SBP: mean difference (MD)= -7.47,95% confidence intervals (CI):-10.43 to -4.51,I2 =0%; DBP: -4.22,-6.26 to -2.18, 0%).A subgroup analysis of 4 trials also showed acupuncture combined with medication was superior to medication on efficacy rate (n=230, odds ratio (OR)=4.19, 95%CI: 1.65 to 10.67, I2 =0%). | PLoS One. 2015 Jul 24;10(7):e0127019. doi: 10.1371/journal.pone.0127019. eCollection 2015. | Blood Pressure | Review |
| 26207806 | Our review provided evidence of acupuncture as an adjunctive therapy to medication for treating hypertension, while the evidence for acupuncture alone lowing BP is insufficient. | PLoS One. 2015 Jul 24;10(7):e0127019. doi: 10.1371/journal.pone.0127019. eCollection 2015. | Blood Pressure | Review |
| 26207806 | But two previous systematic reviews claimed that the evidence of acupuncture for lowering blood pressure (BP) was inconclusive, mainly due to the paucity of rigorous trials. | PLoS One. 2015 Jul 24;10(7):e0127019. doi: 10.1371/journal.pone.0127019. eCollection 2015. | Blood Pressure | Review |
| 26207806 | 5 trial reported SBP and DBP change magnitude(presented as mean ± SD) between baseline and post-intervention as principal outcomes and after excluding one trialfrom meta-analysis because it reported BP value as medians and inter-quatile ranges,2 of them were pooled in the subgroup of acupuncture versus sham acupuncture. | PLoS One. 2015 Jul 24;10(7):e0127019. doi: 10.1371/journal.pone.0127019. eCollection 2015. | Blood Pressure | Review |
| 26207806 | Considering it, some argued that acupuncture did lower blood pressure but the effect weaken or even lost when shoehorning it into a rigorously designed western-type clinical trial. | PLoS One. 2015 Jul 24;10(7):e0127019. doi: 10.1371/journal.pone.0127019. eCollection 2015. | Blood Pressure | Review |
| 26207806 | In summary, our review provided evidence of efficacy of acupuncture as an adjunctive therapy to western medicine for treating hypertension, while the evidence for acupuncture alone lowing BP is insufficient. | PLoS One. 2015 Jul 24;10(7):e0127019. doi: 10.1371/journal.pone.0127019. eCollection 2015. | Blood Pressure | Review |
| 29063107 | Evidence-based blood pressure reducing actions of electroacupuncture: mechanisms and clinical application | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Blood Pressure | Review |
| 29063107 | The downsides from pharmacological therapy have led to consideration of additional treatments, including acupuncture, which evokes endogenous neural-hormonal systems to lower blood pressure. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Blood Pressure | Review |
| 29063107 | Acupuncture did not improve supply (i.e., coronary blood flow) but lessened demand since it blunted the reflex elevation in blood pressure. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Blood Pressure Blood Flow | Review |
| 29063107 | For example, a follow-up study showed that the opioid system played a prominent role in the blood pressure and ischemia reducing effects of acupuncture (Fig. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Blood Pressure | Review |
| 29063107 | Furthermore, selective blockade of the actions or release of neurotransmitters in the hypothalamus, including the paraventricular and arcuate nuclei, midbrain ventrolateral periaqueductal gray and brain stem unclei raphé pallidus and rostral ventrolateral medulla likewise blocks the action of electroacupuncture on reflex elevations in blood pressure. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Blood Pressure | Review |
| 29063107 | Both manual acupuncture and electroacupuncture exert similar reductions in blood pressure transiently elevated during reflex abdominal visceral organ stimulation to evoke sympathoexcitation. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Blood Pressure | Review |
| 29063107 | Low frequency, as opposed to high frequency electroacupuncture is optimal for lowering elevated blood pressure. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Blood Pressure | Review |
| 29063107 | These point specific cardiovascular actions of acupuncture define locations on peripheral nerves that exert the largest blood pressure lowering responses as well as control points that have little or no effect on cardiovascular function. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Cardiovascular Blood Pressure | Review |
| 29063107 | When blood pressure is elevated, stimulation of either the median or deep peroneal nerves innervating deep somatic structures leads to blood pressure decreases because they provide substantial modulatory input to the rostral ventrolateral medulla, a brain stem region containing premotor sympathetic neurons that during acupuncture downregulates sympathetic outflow, compared to more superficial radial and peroneal sensory nerves that ultimately project less to this autonomic nucleus. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Blood Pressure | Review |
| 29063107 | Finally, although acupuncture can lower repeated short-term reflex elevations in blood pressure for one to two hours, recent studies have focused on experimental hypertension, to demonstrate that repeated sequential application every second or third day can produce blood pressure depression lasting for several days. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Blood Pressure Depression | Review |
| 29063107 | These data strongly suggest that if acupuncture is applied in a standardized manner to stimulate sensory pathways shown to be effective experimentally, systolic and, to a lesser extent, diastolic blood pressure are lowered slowly and for a prolonged period and that monthly reapplication may be able to maintain lower blood pressures. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Blood Pressure | Review |
| 29063107 | Reflex increases in arterial blood pressure (AP) and myocardial wall thickening (Wth) are reduced with electroacupuncture (EA) in cats. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Blood Pressure | Review |
| 29063107 | Repetitive electroacupuncture (EA) treatment (twice weekly) reduces blood pressure in cold-induced hypertension (CIH), an environmental model of sustained high blood pressure in rats. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Blood Pressure | Review |
| 29063107 | Systolic (panel A, SBP), diastolic (panel B, DBP) and mean (panel C, MBP) blood pressures averaged over 24 h were reduced in 33 hypertensive patients treated with electroacupuncture (EA) bilaterally at PC5-6 + ST36-37 active acupoints for eight weeks. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Blood Pressure | Review |
| 29063107 | Following a course of eight weeks of weekly acupuncture therapy, continued monthly EA treatment maintained a low systolic blood pressure relative to pre-EA control (Significant decrease in SBP is indicated with *). | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Blood Pressure | Review |
| 29735972 | Pooled results demonstrate that acupuncture plus anti-hypertensive drugs is better than anti-hypertensive drugs alone at reducing systolic and diastolic blood pressure (SBP and DBP). | Med Sci Monit. 2018 May 8;24:2946-2969. doi: 10.12659/MSM.909995. | Blood Pressure | Review |
| 29735972 | However, studies reveal that using acupuncture alone or anti-hypertensive drugs alone do not differ in the effect on lowering blood pressure. | Med Sci Monit. 2018 May 8;24:2946-2969. doi: 10.12659/MSM.909995. | Blood Pressure | Review |
| 29735972 | Search strategy terms were (acupuncture OR electroacupuncture OR acupoint) AND (high blood pressure OR hypertension OR blood pressure) AND (randomized controlled trial OR controlled clinical trial OR randomized OR clinical trials). | Med Sci Monit. 2018 May 8;24:2946-2969. doi: 10.12659/MSM.909995. | Blood Pressure | Review |
| 29735972 | Two studies with 170 patients compared the treatments of acupuncture plus anti-hypertensive drugs and sham acupuncture plus anti-hypertensive drugs treatments on blood pressure. | Med Sci Monit. 2018 May 8;24:2946-2969. doi: 10.12659/MSM.909995. | Blood Pressure | Review |
| 29735972 | Our findings also show that lowering of blood pressure is similar in treatments with acupuncture alone and with anti-hypertensive drugs alone. | Med Sci Monit. 2018 May 8;24:2946-2969. doi: 10.12659/MSM.909995. | Blood Pressure | Review |
| 29735972 | Blood pressure changes are similar for sham acupuncture and acupuncture treatments. | Med Sci Monit. 2018 May 8;24:2946-2969. doi: 10.12659/MSM.909995. | Blood Pressure | Review |
| 29735972 | Moreover, pooled data from 3 studies showed that blood pressure changes are similar for treatments with electro-acupuncture and anti-hypertensive drugs alone. | Med Sci Monit. 2018 May 8;24:2946-2969. doi: 10.12659/MSM.909995. | Blood Pressure | Review |
| 29844696 | Longhurst and Tjen-A-Looi reported that acupuncture stimulation regulated cardiovascular function (blood pressure), whereby neurotransmitter release and neuromodulation in the hypothalamus and several cardiovascular nuclei in the brain stem mediated acupuncture effects. | J Inflamm Res. 2018 May 17;11:227-237. doi: 10.2147/JIR.S141198. eCollection 2018. | Cardiovascular Blood Pressure | Review |
| 29861766 | In the remaining one study, one patient from the neostigmine group suffered from full-body tremor 5 minutes after the intramuscular injection of neostigmine, which was spontaneously resolved 10 minutes later; no other abnormality was found except for slightly higher blood pressure and heart rate; in contrast, no adverse event was found in the acupuncture group. | Evid Based Complement Alternat Med. 2018 May 14;2018:2072091. doi: 10.1155/2018/2072091. eCollection 2018. | Heart Rate Blood Pressure | Review |
| 30365567 | No evidence from meta-analysis has been found regarding post-intervention or long-term effect on blood pressure control for acupuncture compared to sham intervention. | PLoS One. 2018 Oct 26;13(10):e0206288. doi: 10.1371/journal.pone.0206288. eCollection 2018. | Blood Pressure | Review |
| 30365567 | No analysis can be conducted on RCTs focusing on alcohol-dependence and no evidence of the effect of acupuncture treatments on high blood pressure was shown based on meta-analysis. | PLoS One. 2018 Oct 26;13(10):e0206288. doi: 10.1371/journal.pone.0206288. eCollection 2018. | Blood Pressure | Review |
| 30854010 | Moreover, acupuncture induced the feeling of satiety after meal blood-pressure-harmonic-variability responses, including decreases in food intake and increases in energy consumption on the obesity-affected side, while no significant changes were found on the contralateral side. | Evid Based Complement Alternat Med. 2019 Feb 3;2019:5796381. doi: 10.1155/2019/5796381. eCollection 2019. | Blood Pressure | Review |
| 30855351 | Secondly, acupuncture could optimize the patient's preoperative condition that improves the function and reserve of vital organs, stabilizes the blood pressure and blood sugar, and reduces the risk of intraoperative anesthesia, which is the prerequisite for successful operation, and in turn, could reduce the postoperative complications and accelerate patient rehabilitation. | Chin Med J (Engl). 2019 Mar 20;132(6):707-715. doi: 10.1097/CM9.0000000000000123. | Postoperative Complications Blood Pressure | Review |
| 30855351 | Furthermore, acupuncture reduced blood pressure by inhibiting sympathetic excitability, as well as norepinephrine, renin, and aldosterone concentration controls. | Chin Med J (Engl). 2019 Mar 20;132(6):707-715. doi: 10.1097/CM9.0000000000000123. | Blood Pressure | Review |
| 30855351 | In contrast, a study reported acupuncture treatment in essential hypertension, the changes of systolic blood pressure and diastolic blood pressure were similar between both acupuncture and sham acupuncture treatments. | Chin Med J (Engl). 2019 Mar 20;132(6):707-715. doi: 10.1097/CM9.0000000000000123. | Blood Pressure | Review |
| 30984420 | Much evidence has demonstrated that acupuncture as an adjunctive therapy can lower blood pressure in patients with hypertension, but the mechanism of its action is unclear. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | We found that the mechanism whereby acupuncture lowers blood pressure is related to the regulation of renin-angiotensin-aldosterone system, vascular endothelium, oxidative stress, neuroendocrine system, and so on. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | Acupuncture is able to lower BP, resulting in medication dosage reduction, medication types reduction, and fewer side effects, which is regarded as an adjunctive therapy for hypertension. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Dosage of Medication Side Effects Blood Pressure | Review |
| 30984420 | According to up-to-date clinical studies, acupuncture treatment exerts a good effect in lowering BP, and so its usage has attracted increased attention. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | The results of our previous clinical study have found that, after acupuncture treatment, there is a decrease in 24-hour systolic and diastolic BP (from 145.10 ± 9.28 mmHg to 140.70 ± 9.59 mmHg [P< 0.0001], and 88.35 ± 7.92 mmHg to 85.86 ± 7.95 mmHg [P = 0.0024], respectively) and an improvement in circadian BP rhythm in patients with mild hypertension. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | Acupuncture lowers BP by decreasing the activity of rennin, demonstrating that the effect of lowering BP is partly due to a decrease in renin secretion. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | A large number of animal experiments have shown that acupuncture can lower BP by decreasing the levels of ACE and Ang II receptors (AT1R, AT2R) and decreasing the plasma content of Ang II. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | Recent studies showed that acupuncture-reduced BP may be due to the inhibition of Nox, enhancing antioxidant capacity and reducing the level of ROS. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | explored the mechanism of acupuncture in reducing BP from the perspective of oxidative/antioxidant enzymes, and their results demonstrated that acupuncture could reduce Nox, increase catalase (CAT), and inhibit oxidative stress after needling Renying (ST9). | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | found that the mechanism whereby acupuncture lowers BP may increase the antioxidant enzymes (SOD, glutamate dehydrogenase 1, aldehyde dehydrogenase 2, glutathione S-transferase M5, Rho GDP dissociation inhibitor 1, and DJ-1 protein) in the medulla and improve oxidative stress, by needling Taichong (LR3) of spontaneously hypertensive rats (SHR). | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | If the dynamic equilibrium of EDRF and EDCF is broken which would lead to disorders of vascular tension and elevation of BP, it has been reported that acupuncture is able to improve endothelial dysfunction and the diastolic function of blood vessels. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | Animal studies have shown that acupuncture can lower BP by reducing endothelin A receptor (ETAR) and ET-1 production. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | To sum up, acupuncture treatment can lower BP by restoring the equilibrium of EDRF and EDCF in vascular endothelial cells. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | All the evidence suggests that acupuncture can reduce inflammatory factors, which may affect the RAAS system and endothelial function, resulting in reduction of BP. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | Also, a study showed that the complex interaction between the autonomic nerve center of brain stem and the antiopiate stimuli and other chemical mediators determines the degree of influence of acupuncture on BP. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | found that acupuncture can lower BP in SHR and, at the same time, improve metabolic disturbances, such as increased urinary metabolites α-ketoglutarate, N-acetylglutamic acid, and betaine. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | Acupuncture simultaneously lowered 24-hour BP and reversed OA and MI abnormalities. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | Studies have reported that acupuncture can improve cerebral blood flow and increase microvascular openings in the hippocampus CA1 area by increasing the proportion of Bcl-2/Bax and inhibiting apoptosis, in order to lower BP and prevent target organ damage. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Microcirculation Blood Pressure Blood Flow | Review |
| 30984420 | Acupuncture can not only lower BP but can also protect the target organ. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | The animal study and clinical trial has demonstrated that sham acupuncture treatment (acupuncture on the nonacupoints) could not lower BP.When irrelevant acupoints (e.g., LI6, LI7, GB37, GB38, and GB39) were selected, the antihypertensive effect is not achieved too. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 30984420 | Acupuncture can protect target organs in addition to reducing BP. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Blood Pressure | Review |
| 31467579 | It is presumed that this may be an important molecular mechanism for acupuncture and moxibustion to regulate blood pressure and improve cardiovascular remodeling. | Evid Based Complement Alternat Med. 2019 Jul 31;2019:8138017. doi: 10.1155/2019/8138017. eCollection 2019. | Cardiovascular Blood Pressure | Review |
| 31772597 | However, the study also noted that a single acupuncture cannot reduce the resting sympathetic nerve activity of patients with HF, and the regulation of HR and blood pressure is not obvious. | Evid Based Complement Alternat Med. 2019 Oct 20;2019:6074967. doi: 10.1155/2019/6074967. eCollection 2019. | Heart Rate Blood Pressure | Review |
| 32523527 | As a component of traditional Chinese medicine (TCM), acupuncture has the potential to lower blood pressure (BP) in patients with hypertension. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | Emerging evidence indicates that the acupuncture-induced inhibition of high BP occurs through the activation of the pathway in the afferent, central, and efferent pathways. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | This review focuses on the clinical and mechanistic studies of acupuncture in modulating BP, which might provide a neurobiological foundation for the effects of acupuncture. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | In recent years, several randomized controlled trials have shown that acupuncture alleviates blood pressure (BP) in patients (Wang et al.,; Zheng et al.,). | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | Animal experiments (Yang et al.,) have also shown that acupuncture has a significant effect on the BP of spontaneously hypertensive rats (SHRs). | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | Experts have shown that acupuncture plays a role in lowering BP through effects on the nervous system [including the afferent pathway, central nervous system (CNS), and efferent pathways] and neurotransmitters. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | Most studies have shown that acupuncture can decrease BP in hypertensive patients. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | reported that compared with participants who received sham acupuncture and those on a waiting-list group, individuals who received active acupuncture (three sessions per week, 6-week treatment) showed better improvements in systolic blood pressure (SBP) and diastolic blood pressure (DBP) at weeks 6, 9 and 12. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | These data indicate that acupuncture is effective at reducing BP in patients with hypertension. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | However, trials estimating the BP-lowering effects of acupuncture have shown diverse results. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | There was no significant difference in BP reduction, which between the acupuncture group and the sham acupuncture group from its baseline to 10 weeks. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | Although these experimental results are controversial, however, most of the other experiments indicate that acupuncture plays a role in reducing BP. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | Hypertensive patients without medication received electroacupuncture (EA) at P5-6+ST36-37 (Neiguan-Jianshi+Zusanli-Shangjuxu, Figure 1) and then were assessed with 24 h by ambulatory BP monitoring. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | Hence, we need to explain why acupuncture lowers BP from the perspective of each of these components. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | Studies show that manual acupuncture-like stimulation of a hindleg in rats modifies BP, heart rate, and the secretion rate of adrenal medullary catecholamine hormones (adrenaline and noradrenaline; Uchida et al.,). | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Heart Rate Blood Pressure | Review |
| 32523527 | These findings reveal that afferent fibers are involved in the ability of acupuncture to lower BP. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | Acupuncture influences BP mainly through these two types of efferent nerves. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | These data suggest that acupuncture lowers BP through sympathetic nerves. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | Hsu) study, acupuncture at TF4 (shenmen acupoint, Figure 1) and EX-HN1 (Sishencong acupoint, Figure 1) reduced BP, slowed the heart rate and activated the vagal nerves. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Heart Rate Blood Pressure | Review |
| 32523527 | Acupuncture is effective at improving BP because it affects the CNS (Hua and Jie,). | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | Thus, this EA action in the IML shows that acupuncture also modulates sympathetic outflow from the spinal cord (Tjen-A-Looi et al.,; Zhou et al.,), suggesting that sympathetic nerves in the spinal cord play a role in BP regulation. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | Neuronal pathways and mechanisms underlying the effect of acupuncture for different brain nuclei in blood pressure (BP) regulation. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | Neurotransmitters Responsible for Acupuncture-Mediated BP Regulation | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | Neurotransmitters are involved in the action of acupuncture on modulating BP (Flachskampf et al.,). | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | Although acupuncture plays a significant role in decreasing BP and heart rate in pentobarbital-anesthetized rats, these responses are related to the activation of GABAergic neurons instead of opioid neurons (Uchida et al.,). | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Heart Rate Blood Pressure | Review |
| 32523527 | An increasing amount of evidence shows that the effect of acupuncture on reducing BP occurs through various pathways, including acupoints, afferent nerves, the CNS, efferent nerves, and neurotransmitters. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32523527 | Rigorous clinical studies and mechanistic studies are required to design future protocols for using acupuncture to lower BP. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Blood Pressure | Review |
| 32684734 | When it comes to the effects of acupuncture on modulating the cardiovascular system, stimulations of the limbs, chest, and abdomen all produce a similar effect in terms of heart rate and blood pressure, yet whether the effect is excited or suppressed depends on the intensity of the stimulus (or what type of fiber is activated) and the tissue structure (skin or muscle). | World J Gastroenterol. 2020 Jun 21;26(23):3182-3200. doi: 10.3748/wjg.v26.i23.3182. | Heart Rate Cardiovascular Blood Pressure | Review |
| 33738923 | Because of mixed results in trials and numerous limitations, the American Heart Association does not recommend yoga or acupuncture to lower BP. Biofeedback techniques have been proven effective and may be used in clinical practice to lower BP. | J Clin Hypertens (Greenwich). 2021 Jul;23(7):1275-1283. doi: 10.1111/jch.14236. Epub 2021 Mar 18. | Blood Pressure | Review |
| 33738923 | Acupuncture, may also be helpful in lowering BP in prehypertension and stage I hypertension patients. | J Clin Hypertens (Greenwich). 2021 Jul;23(7):1275-1283. doi: 10.1111/jch.14236. Epub 2021 Mar 18. | Blood Pressure | Review |
| 34122180 | AEs associated with acupuncture treatment were hematoma (16/146), feeling pain when inserting needle (4/154), dizziness (8/147), palpitation (4/83), dry mouth (1/41), nausea and/or vomiting (6/85), changes of character of stool (4/50), and sweating (5/44); AEs associated with standard (antidepressant or antidepressant combined with HRT) included fatigue (17/30), palpitation (25/206), headache (3/62), dizziness (40/472), sleep disturbance (25/250), sweating (10/30), dry mouth and/or halitosis (41/229), indigestion (1/32), loss of appetite (5/60), stomachache (18/105), nausea and/or vomiting (18/303), constipation (14/76), diarrhea (4/92), changes of character of stool (6/29), dysphoria (14/96), for excitation and agitation (2/30), akathisia (1/30), spasmus (1/60), breast distending pain (16/156), leukorrhagia (2/60), skin symptom (1/30), and elevated blood pressure (2/50). | Front Psychiatry. 2021 May 28;12:666988. doi: 10.3389/fpsyt.2021.666988. eCollection 2021. | Insomnia Nausea and Vomiting Blood Pressure | Review |
| 34335848 | Clinical practice and some experiments have proven that acupuncture is effective for BP. | Evid Based Complement Alternat Med. 2021 Jul 13;2021:9953986. doi: 10.1155/2021/9953986. eCollection 2021. | Blood Pressure | Review |
| 34335848 | Not only is acupuncture effective for complications related to HD, such as uremic symptoms, insomnia, and fatigue, but also it is able to improve renal function, proteinuria, BP, anemia, and pain in CKD patients. | Evid Based Complement Alternat Med. 2021 Jul 13;2021:9953986. doi: 10.1155/2021/9953986. eCollection 2021. | Insomnia Blood Pressure Kidney | Review |
| 34437474 | In addition, many other bidirectional regulation features of acupuncture embody similar therapeutic effects of promoting sweating and inhibiting sweating, raising and lowering blood pressure and treating urinary retention and incontinence. | Vet Sci. 2021 Jul 30;8(8):149. doi: 10.3390/vetsci8080149. | Blood Pressure Urinary Retention | Review |
| 34671411 | Following terms combined were used for searching: acupuncture OR acupoint, hypertension OR blood pressure, animal OR pre-clinical study OR mechanism study. | Evid Based Complement Alternat Med. 2021 Oct 11;2021:8171636. doi: 10.1155/2021/8171636. eCollection 2021. | Blood Pressure | Review |
| 34671411 | Studies were excluded if any of the following standards was met: the HBP was induced by stress or adrenaline administration and was not lasting; studies were conducted to compare the effects of different acupuncture methods on hypertension, with no treatment or sham-acupuncture treatment as control; studies did not use BP values as outcomes; and duplicate publications. | Evid Based Complement Alternat Med. 2021 Oct 11;2021:8171636. doi: 10.1155/2021/8171636. eCollection 2021. | Blood Pressure | Review |
| 34671411 | To explore the impact of factors potentially influencing the BP outcome, subgroup analyses were conducted for the following factors: acupuncture methods used, age of acupuncture initiation, age of BP measurement, duration of each acupuncture session, total acupuncture sessions, and acupuncture treatment frequency. | Evid Based Complement Alternat Med. 2021 Oct 11;2021:8171636. doi: 10.1155/2021/8171636. eCollection 2021. | Blood Pressure | Review |
| 34671411 | Although the effectiveness of acupuncture's antihypertension in most studies was demonstrated by the value of BP, the ultimate goal of hypertension treatment is to prevent target organ damage and decrease mortality. | Evid Based Complement Alternat Med. 2021 Oct 11;2021:8171636. doi: 10.1155/2021/8171636. eCollection 2021. | Blood Pressure | Review |
| 35725779 | Animal models showed that that electroacupuncture leads to the inhibition of the neuronal network that affect the cardiovascular sympathetic neurons, reducing blood pressure. | Blood Rev. 2022 Nov;56:100985. doi: 10.1016/j.blre.2022.100985. Epub 2022 Jun 13. | Cardiovascular Blood Pressure | Review |
| 36107536 | The acupuncture is beneficial to improve the systolic blood pressure of patients, and the effect of acupuncture on diastolic blood pressure is better than that of sham acupuncture. | Medicine (Baltimore). 2022 Sep 2;101(35):e30086. doi: 10.1097/MD.0000000000030086. | Blood Pressure | Review |
| 36107536 | This review summarizes the available evidence and underpins findings of the acupuncture exhibited the therapeutic role in eliminating metabolic risk factors for stroke, including systolic blood pressure, weight loss, glycemic index and cholesterol. | Medicine (Baltimore). 2022 Sep 2;101(35):e30086. doi: 10.1097/MD.0000000000030086. | Blood Pressure | Review |
| 36107536 | The Chinese search MeSH terms included acupuncture, body acupuncture, electroacupuncture, hypertension, regulating blood pressure, diabetes, blood sugar, insulin resistance, hyperlipidemia, lipid metabolism, obesity, overweight, systematic evaluation, meta-analysis, and meta-evaluation. | Medicine (Baltimore). 2022 Sep 2;101(35):e30086. doi: 10.1097/MD.0000000000030086. | Blood Pressure | Review |
| 36107536 | A total of ten articles evaluated the effects of acupuncture on blood pressure improvement. | Medicine (Baltimore). 2022 Sep 2;101(35):e30086. doi: 10.1097/MD.0000000000030086. | Blood Pressure | Review |
| 36107536 | Sixteen articles evaluated the reduction of systolic blood pressure due to acupuncture, western medicine, electroacupuncture, and acupuncture + lifestyle, and 3 articles showed that acupuncture + western medicine improved systolic blood pressure better than sham acupuncture + western medicine. | Medicine (Baltimore). 2022 Sep 2;101(35):e30086. doi: 10.1097/MD.0000000000030086. | Blood Pressure | Review |
| 36107536 | Four articles showed that acupuncture was better than sham acupuncture in improving systolic blood pressure. | Medicine (Baltimore). 2022 Sep 2;101(35):e30086. doi: 10.1097/MD.0000000000030086. | Blood Pressure | Review |
| 36107536 | Seven articles showed that acupuncture + western medicine improved systolic blood pressure better than western medicine. | Medicine (Baltimore). 2022 Sep 2;101(35):e30086. doi: 10.1097/MD.0000000000030086. | Blood Pressure | Review |
| 36107536 | Seven articles showed that acupuncture improved systolic blood pressure better than western medicine.. Sixteen articles demonstrated that the effect of acupuncture on diastolic blood pressure was better than that of sham acupunctur. | Medicine (Baltimore). 2022 Sep 2;101(35):e30086. doi: 10.1097/MD.0000000000030086. | Blood Pressure | Review |
| 36107536 | Acupuncture improved diastolic blood pressure better than western medicine. | Medicine (Baltimore). 2022 Sep 2;101(35):e30086. doi: 10.1097/MD.0000000000030086. | Blood Pressure | Review |
| 36107536 | Acupuncture + western medicine improved diastolic blood pressure better than western medicine. | Medicine (Baltimore). 2022 Sep 2;101(35):e30086. doi: 10.1097/MD.0000000000030086. | Blood Pressure | Review |
| 36107536 | Related studies have shown that acupuncture is beneficial to improve the systolic blood pressure of patients, and the effect of acupuncture on diastolic blood pressure is better than that of sham acupuncture. | Medicine (Baltimore). 2022 Sep 2;101(35):e30086. doi: 10.1097/MD.0000000000030086. | Blood Pressure | Review |
| 36107536 | This review summarizes the available evidence and underpins findings of the acupuncture exhibited the therapeutic role in eliminating metabolic risk factors for stroke, including systolic blood pressure, weight loss, glycemic index and cholesterol. | Medicine (Baltimore). 2022 Sep 2;101(35):e30086. doi: 10.1097/MD.0000000000030086. | Blood Pressure | Review |
| 36148057 | Based on co-occurrences and cluster analysis of 257 keywords, three research frontiers and hotspots were identified: acupuncture for blood pressure regulation, acupuncture for coronary heart disease, and acupuncture for regulation of heart rate. | Front Cardiovasc Med. 2022 Sep 6;9:920491. doi: 10.3389/fcvm.2022.920491. eCollection 2022. | Heart Rate Blood Pressure | Review |
| 36148057 | In recent years, with the development of the mechanism of acupuncture in analgesia, anti-inflammatory and nerve regulation, and effects in withdrawal syndrome, weight loss, and blood pressure regulation, acupuncture has become a potential therapeutic method for reducing cardiovascular disease risk factors, reducing the number of acute attacks, improving the results of electrocardiography, and alleviating anxiety and depression. | Front Cardiovasc Med. 2022 Sep 6;9:920491. doi: 10.3389/fcvm.2022.920491. eCollection 2022. | Cardiovascular Anxiety Blood Pressure Depression | Review |
| 36148057 | With the deepening of research on acupuncture and neuroendocrine network theory, acupuncture gradually became a new star in the regulation strategy of blood pressure. | Front Cardiovasc Med. 2022 Sep 6;9:920491. doi: 10.3389/fcvm.2022.920491. eCollection 2022. | Blood Pressure | Review |
| 36148057 | However, more than 5 meta-analyses suggested that, subject to a high risk of bias, undesirable sham acupuncture control and insufficient treatment and follow-up period, there was no evidence for the sustained blood pressure lowering effect of acupuncture, which is required for the long-term management of chronic hypertension. | Front Cardiovasc Med. 2022 Sep 6;9:920491. doi: 10.3389/fcvm.2022.920491. eCollection 2022. | Blood Pressure | Review |
| 36148057 | Acupuncture can increase neuronal nitric oxide synthase (nNOS) expression in the arcuate nucleus (ARC) and ventrolateral periaqueductal grey (vlPAG) to inhibit the sympathetic nervous system, thereby lowering blood pressure. | Front Cardiovasc Med. 2022 Sep 6;9:920491. doi: 10.3389/fcvm.2022.920491. eCollection 2022. | Blood Pressure | Review |
| 36148057 | In neuroimaging studies, acupuncture stimulation was related to several brain regions in which the RVLM is responsible for the regulation of blood pressure and sympathetic output. | Front Cardiovasc Med. 2022 Sep 6;9:920491. doi: 10.3389/fcvm.2022.920491. eCollection 2022. | Blood Pressure | Review |
| 36148057 | The three most striking frontiers are acupuncture for blood pressure regulation and hypertensive heart disease, acupuncture for coronary heart disease, and acupuncture for regulation of heart rate. | Front Cardiovasc Med. 2022 Sep 6;9:920491. doi: 10.3389/fcvm.2022.920491. eCollection 2022. | Heart Rate Blood Pressure | Review |
| 36570846 | An increasing number of studies have also demonstrated that acupuncture can regulate blood pressure, pupil size, skin conductance, skin temperature, heart rate (HR) and/or pulse rate, and heart rate variability (HRV) mediated by the ANS. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Heart Rate Blood Pressure Skin Temperature | Review |
| 36570846 | Thus, the PVN and its projections to the VLM are essential in processing acupuncture treatment of elevated blood pressure through a PVN-opioid mechanism. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Blood Pressure | Review |
| 36570846 | By stimulating the hippocampus-NTS-vagus nerve pathway, electroacupuncture at HT7-HT5 can decrease HR, increase mean arterial pressure (MAP), and increase the HR-blood pressure product (RPP) in myocardial ischemia-susceptible rats. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Heart Rate Blood Pressure | Review |
| 36570846 | For example, electroacupuncture at ST36 and PC6 can improve gastrointestinal motility in rats with gastric dilatation by stimulating vagus nerves; and electroacupuncture at PC5 and PC6 can reduce cardiovascular excitatory response and regulate blood pressure by the stimulating the vagus nerve and inhibiting sympathetic nerves. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Cardiovascular Blood Pressure | Review |
| 36607887 | Combined acupuncture-medicine anesthesia significantly increases the anesthesia significance rate, reduces the intraoperative heart rate, and blood pressure, and reduces the incidence of postoperative adverse reactions. | Medicine (Baltimore). 2023 Jan 6;102(1):e32582. doi: 10.1097/MD.0000000000032582. | Heart Rate Adverse Reactions Blood Pressure | Review |
| 36607887 | However, AA, which is developed from the traditional Chinese acupuncture analgesia, has an optimal analgesic effect by affecting the production and release of neurotransmitters, significantly controlling the increase in blood pressure and heart rate during surgery and reduces the cardiovascular response after cervical plexus block. | Medicine (Baltimore). 2023 Jan 6;102(1):e32582. doi: 10.1097/MD.0000000000032582. | Analgesic Effect Heart Rate Cardiovascular Blood Pressure | Review |
| 36607887 | Meta-analysis of the RCTs comparing blood pressure between acupuncture group and control group. | Medicine (Baltimore). 2023 Jan 6;102(1):e32582. doi: 10.1097/MD.0000000000032582. | Blood Pressure | Review |
| 36711409 | A, acupuncture; B, aerobic exercise; C, combination exercise; D, DASH; E, high Potassium; F, isometric exercise; G, lifestyle; H, meditation; I, normal exercise; J, reduced alcohol; K, resistance exercise; L, salt restriction; M, weight loss; N, yoga; O, usual care; CI, confidence interval; SBP, systolic blood pressure; DBP, diastolic blood pressure. | Front Public Health. 2023 Jan 13;10:1051581. doi: 10.3389/fpubh.2022.1051581. eCollection 2022. | Blood Pressure | Review |
| 36711409 | For DBP, acupuncture (â6.48 mmHg, â11.39 to â1.42; moderate certainty), aerobic exercise (â3.12 mmHg, â5.51 to â0.73; moderate certainty), combination exercise (â4.67 mmHg, â8.56 to â0.79; moderate certainty), isometric exercise (â3.88 mmHg, â6.74 to â0.95; low certainty), lifestyle (â2.56 mmHg, â4.56 to â0.58; moderate certainty), meditation (â5.81 mmHg, â9.41 to â2.19; moderate certainty), normal exercise (â3.32 mmHg, â6.05 to â0.59; low certainty), weight loss (â3.16 mmHg, â6.14 to â0.29; moderate certainty) and yoga (â3.73 mmHg, â6.81 to â0.59; moderate certainty) significantly lowered BP compared with usual care. | Front Public Health. 2023 Jan 13;10:1051581. doi: 10.3389/fpubh.2022.1051581. eCollection 2022. | Blood Pressure | Review |
| 36711409 | We evaluated the effects using a network meta-analysis with BP reduction as the outcome indicator and found that combination exercise, isometric exercise, aerobic exercise, yoga, and normal exercise were the top five in SBP reduction, and acupuncture, meditation, combination exercise, isometric exercise and yoga for DBP reduction. | Front Public Health. 2023 Jan 13;10:1051581. doi: 10.3389/fpubh.2022.1051581. eCollection 2022. | Blood Pressure | Review |
| 36864974 | Acupuncture has already been extensively utilized to treat high blood pressure (hypertension) in several nations. | Cardiovasc Diagn Ther. 2023 Feb 28;13(1):67-82. doi: 10.21037/cdt-22-480. Epub 2022 Dec 15. | Blood Pressure | Review |
| 36864974 | In the treatment of hypertension, electroacupuncture has a beneficial effect on reducing blood pressure. | Cardiovasc Diagn Ther. 2023 Feb 28;13(1):67-82. doi: 10.21037/cdt-22-480. Epub 2022 Dec 15. | Blood Pressure | Review |
| 36864974 | Through a randomized clinical experiment, FA Flachskampf, a professor at Univ Klinikum Erlangen rated second in the frequency of citations, discovered that acupuncture therapy could significantly reduce an average of 24-hour ambulatory blood pressure after six weeks of treatment. | Cardiovasc Diagn Ther. 2023 Feb 28;13(1):67-82. doi: 10.21037/cdt-22-480. Epub 2022 Dec 15. | Blood Pressure | Review |
| 36864974 | Furthermore, DD Kim revealed that one of the mechanisms by which ST-36 electroacupuncture reduces blood pressure is an activation of endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS), and that stomach 36-point (ST-36) electroacupuncture-induced blood pressure reduction operates through the stomach meridian. | Cardiovasc Diagn Ther. 2023 Feb 28;13(1):67-82. doi: 10.21037/cdt-22-480. Epub 2022 Dec 15. | Blood Pressure | Review |
| 36864974 | investigated the mechanism of acupuncture in lowering blood pressure from the viewpoint of oxidative enzymes. | Cardiovasc Diagn Ther. 2023 Feb 28;13(1):67-82. doi: 10.21037/cdt-22-480. Epub 2022 Dec 15. | Blood Pressure | Review |
| 36864974 | Numerous animal studies also demonstrated that acupuncture successfully lowered blood pressure by reducing plasma levels of angiotensin II (Ang II) and angiotensin-converting enzyme and angiotensin II receptors (AT1R, AT2R). | Cardiovasc Diagn Ther. 2023 Feb 28;13(1):67-82. doi: 10.21037/cdt-22-480. Epub 2022 Dec 15. | Blood Pressure | Review |
| 36864974 | In the treatment of hypertension, electroacupuncture has a beneficial effect on the reduction of blood pressure. | Cardiovasc Diagn Ther. 2023 Feb 28;13(1):67-82. doi: 10.21037/cdt-22-480. Epub 2022 Dec 15. | Blood Pressure | Review |
| 36864974 | Electroacupuncture frequency and intensity both have a significant impact on how blood pressure is regulated. | Cardiovasc Diagn Ther. 2023 Feb 28;13(1):67-82. doi: 10.21037/cdt-22-480. Epub 2022 Dec 15. | Blood Pressure | Review |
| 36864974 | According to universal consensus, higher intensity electroacupuncture alters excitability, which raises blood pressure; on the contrary, lower intensity electroacupuncture has an inhibitory impact, which might also reduce blood pressure. | Cardiovasc Diagn Ther. 2023 Feb 28;13(1):67-82. doi: 10.21037/cdt-22-480. Epub 2022 Dec 15. | Blood Pressure | Review |
| 36864974 | Nonetheless, the effect of electroacupuncture intensity on blood pressure remains unknown. | Cardiovasc Diagn Ther. 2023 Feb 28;13(1):67-82. doi: 10.21037/cdt-22-480. Epub 2022 Dec 15. | Blood Pressure | Review |
| 36864974 | Low-frequency electroacupuncture (2 Hz) may cause a decrease in sympathetic tone, dilatation of the systemic arteriole, and a blood pressure-lowering effect. | Cardiovasc Diagn Ther. 2023 Feb 28;13(1):67-82. doi: 10.21037/cdt-22-480. Epub 2022 Dec 15. | Blood Pressure | Review |
| 36864974 | In addition to decreasing blood pressure, acupuncture may shield the target organ. | Cardiovasc Diagn Ther. 2023 Feb 28;13(1):67-82. doi: 10.21037/cdt-22-480. Epub 2022 Dec 15. | Blood Pressure | Review |
| 36864974 | In the treatment of hypertension, electroacupuncture has a beneficial effect on the reduction of blood pressure. | Cardiovasc Diagn Ther. 2023 Feb 28;13(1):67-82. doi: 10.21037/cdt-22-480. Epub 2022 Dec 15. | Blood Pressure | Review |
| 36960418 | In acupuncture and sham acupuncture groups, specific skin symptoms including mild subcutaneous bleeding and pain were reported, while in the western medicine groups, gastrointestinal symptoms including nausea, abdominal pain, dizziness, and low blood pressure were recorded. | Pain Res Manag. 2023 Mar 14;2023:7754876. doi: 10.1155/2023/7754876. eCollection 2023. | Bleeding Nausea and Vomiting Blood Pressure | Review |
| 37168651 | Furthermore, growing evidence has been provided for bio-electric techniques in the treatment of hypertension, with results seen in the fields of renal sympathetic denervation (RDN), carotid baroreflex activation therapy (CBAT) and Chinese medicine electroacupuncture for the lowering of BP. | Biomed Rep. 2023 Apr 18;18(6):38. doi: 10.3892/br.2023.1621. eCollection 2023 Jun. | Blood Pressure Kidney | Review |
| 37168651 | Tjen-A-Looi et al indicated that acupuncture may cause a decrease in sympathetic excitability in the RVLM region by modulating the projections from the paraventricular nucleus to the RVLM and the expression of opioid receptors and γ-aminobutyric acid receptors, which in turn causes a decrease in BP, and a significant decrease in renal vascular resistance was found by Doppler ultrasound measurement of renal artery vascular resistance after at least three sessions of moxibustion treatment at bilateral dorsal acupoints. | Biomed Rep. 2023 Apr 18;18(6):38. doi: 10.3892/br.2023.1621. eCollection 2023 Jun. | Blood Pressure Kidney | Review |
| 37168651 | The efficacy of acupuncture in the treatment of hypertension has been initially recognized, and a randomized controlled clinical trial has indicated that acupuncture may reduce the BP by 3-5 mmHg in patients with hypertension. | Biomed Rep. 2023 Apr 18;18(6):38. doi: 10.3892/br.2023.1621. eCollection 2023 Jun. | Blood Pressure | Review |
| 37168651 | A systematic review compared several sham acupuncture-controlled trials of acupuncture to lower the BP, revealing that the acupuncture group was effective in lowering both SBP and DBP. | Biomed Rep. 2023 Apr 18;18(6):38. doi: 10.3892/br.2023.1621. eCollection 2023 Jun. | Blood Pressure | Review |
| 37168651 | A systematic review comparing acupuncture-controlled trials of RAAS inhibitors suggested that acupuncture was more beneficial than RAAS inhibitors for lowering BP. | Biomed Rep. 2023 Apr 18;18(6):38. doi: 10.3892/br.2023.1621. eCollection 2023 Jun. | Blood Pressure | Review |
| 37168651 | Electroacupuncture also has good antihypertensive efficacy, but superiority over non-current acupuncture for lowering BP has not been demonstrated. | Biomed Rep. 2023 Apr 18;18(6):38. doi: 10.3892/br.2023.1621. eCollection 2023 Jun. | Blood Pressure | Review |
| 37200784 | In a study, acupuncture improved PTSD symptoms by increasing p-mTOR, as well as the upstream protein p-Akt, the downstream protein p-70S6K, p-4E-BP-1, and p-CREB through the mTOR pathway (Oh et al.,) (Figure 4). | Front Behav Neurosci. 2023 May 2;17:1163718. doi: 10.3389/fnbeh.2023.1163718. eCollection 2023. | Blood Pressure | Review |
| 37200784 | (C) In the mTOR pathway, acupuncture improved PTSD symptoms by increasing p-mTOR, as well as the upstream protein, p-Akt, the downstream proteins, p-70S6K and p-4E-BP-1. | Front Behav Neurosci. 2023 May 2;17:1163718. doi: 10.3389/fnbeh.2023.1163718. eCollection 2023. | Blood Pressure | Review |
| 37332744 | Forest plot comparing the (A) heart rate; (B) systolic blood pressure and (C) diastolic blood pressure during extracorporeal shock wave lithotripsy (ESWL) between acupuncture and control groups. | Front Med (Lausanne). 2023 Jun 2;10:1114485. doi: 10.3389/fmed.2023.1114485. eCollection 2023. | Heart Rate Blood Pressure | Review |
| 37675019 | Acupuncture reduces blood pressure by lowering the ET-1 level. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Blood Pressure | Review |
| 37675019 | Moreover, acupuncture reduced local renal sympathetic nerve activity by inhibiting the extracellular regulated protein kinase ½-MAPK pathway to lower blood pressure. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Blood Pressure Kidney | Review |
| 38162142 | Acupuncture, a core technique in the non-pharmacological treatment of Chinese medicine, plays an important role in the treatment of elevated blood pressure. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Blood Pressure | Review |
| 38162142 | This study aimed to systematically evaluate the effect of acupuncture alone or in combination with antihypertensive drugs on the efficiency of reducing blood pressure and controlling blood pressure in elderly patients with hypertension. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Blood Pressure | Review |
| 38162142 | Acupuncture has been used for centuries as an important component of Chinese medicine for the treatment of elevated blood pressure in China and has been widely used internationally for the treatment of cardiovascular and cerebrovascular diseases. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Cardiovascular Blood Pressure | Review |
| 38162142 | Exclusion criteria: (1) Duplicate literature in the library; (2) Case studies, animal experiments, and ethical explorations; (3) Studies with only a summary but no specific data; (4) Non-RCT trials, semi-randomized controlled trials, and self-controlled trials; (5) Involving other forms of acupuncture, such as transcutaneous electrical nerve stimulation, laser acupuncture; (6) Unable to convert blood pressure data units to mmHg. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Blood Pressure | Review |
| 38162142 | Data included: first author, date of publication, number of patients, mean age of patients, acupuncture treatment method, acupuncture points, frequency of acupuncture, acupuncture treatment duration, type of control group, mean blood pressure before treatment, mean blood pressure after treatment, mean blood pressure change, treatment efficiency, and adverse events. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Blood Pressure | Review |
| 38162142 | In order to compare the efficacy of acupuncture and drugs in lowing blood pressure in the elderly population, four RCTs including 420 subjects were analyzed to assess the efficiency. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Blood Pressure | Review |
| 38162142 | First, acupuncture alone or combined with drugs outperforms drugs-only treatment, as evidenced by an improvement in blood pressure values after the interventions. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Blood Pressure | Review |
| 38162142 | A randomized controlled trial found a reduction in both systolic blood pressure (SBP) and diastolic blood pressure (DBP) after 6 weeks of biweekly acupuncture treatment compared to the sham acupuncture group. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Blood Pressure | Review |
| 38162142 | Previous studies have shown that acupuncture plays a role in lowering blood pressure through its effects on the nervous system (including afferent pathways, central nervous system, and efferent pathways) and neurotransmitters. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Blood Pressure | Review |
| 38162142 | Yang M compared the levels of 47 compounds that have been reported in the literature in plasma before and after patients received acupuncture by a metabolomic approach to screen for compounds that may be relevant to the lowering of blood pressure by acupuncture. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Blood Pressure | Review |
| 38162142 | Finally, they found that there were significant differences in the levels of oleic acid and inositol before and after acupuncture and that acupuncture reduced the plasma levels of these two compounds in hypertensive patients, and inferred that they may be related to the mechanism of blood pressure lowering by acupuncture. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Blood Pressure | Review |
| 38162142 | Acupuncture regulates inositol (an insulin-like characteristic protein with insulin-sensitizing properties) levels probably by improving vascular smooth muscle diastolic capacity and affecting blood pressure. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Blood Pressure | Review |
| 38162142 | Therefore, as a safe and effective adjuvant therapy for hypertension, acupuncture has been widely used in clinics, and has a significant effect on reducing blood pressure. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Blood Pressure | Review |
| 38162142 | Meanwhile, when acupuncture treatments are performed, low-frequency, long-term treatment will have a more pronounced effect on lowering blood pressure. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Blood Pressure | Review |
| 38162142 | Therefore, to confirm the evaluation of the efficacy of acupuncture in elderly patients with hypertension, more attention should be paid to endpoint events, such as distant-related cardiovascular events and target organ damage, in addition to the observation of blood pressure values. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Cardiovascular Blood Pressure | Review |
| 38162142 | Besides, when acupuncture treatments are performed, low-frequency, long-term treatment will have a more pronounced effect on lowering blood pressure, which can improve remission rates as well as reduce the number of elderly people using antihypertensive drugs. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Blood Pressure | Review |
| 2125872 | The fluctuation of blood pressure was lower than that of the control group. | Zhen Ci Yan Jiu. 1990;15(3):170-2. | Blood Pressure | Clinic |
| 2487311 | In acupuncture anesthesia, blood pressure, pulse rate and respiration were stable during operation, and blood loss was less than in epidural or local anesthesia. | Fukushima J Med Sci. 1989 Dec;35(2):45-52. | Heart Rate Bleeding Blood Pressure | Clinic |
| 19055289 | The dosage of the narcotic, changes of both blood pressure and heart rate during operation, before and after extubation and the pain degree, etc. | Zhongguo Zhen Jiu. 2008 Nov;28(11):826-8. | Heart Rate Blood Pressure | Clinic |
| 19055289 | (2) Both blood pressure and heart rate during operation, before and after extubation in the observation group were lower than those before operation (P < 0.01), and both the blood pressure and heart rate during operation in the control group were lower than those before operation (P < 0.01). | Zhongguo Zhen Jiu. 2008 Nov;28(11):826-8. | Heart Rate Blood Pressure | Clinic |
| 19055289 | The blood pressure after extubation in the observation group was significantly lower than that of the control group (P < 0.01), and the heart rate before and after extubation in the observation group was significantly lower than that of the control group (P < 0.01). | Zhongguo Zhen Jiu. 2008 Nov;28(11):826-8. | Heart Rate Blood Pressure | Clinic |
| 21290841 | Visual Analogue Score (VAS) was used to evaluate the pain extent after biopsy and blood pressure and heart rate were monitored before, during and after operation, separately. | Zhongguo Zhen Jiu. 2010 Dec;30(12):1015-7. | Heart Rate Blood Pressure | Clinic |
| 21290841 | Additionally, in group B, blood pressure and heart rate during and after operation were higher remarkably than those before operation (all P < 0.05). | Zhongguo Zhen Jiu. 2010 Dec;30(12):1015-7. | Heart Rate Blood Pressure | Clinic |
| 21290841 | Moreover, in group B, blood pressure during operation and heart rate during and after operation were all higher apparently than those in group A (all P < 0.05). | Zhongguo Zhen Jiu. 2010 Dec;30(12):1015-7. | Heart Rate Blood Pressure | Clinic |
| 21290841 | CONCLUSION: Acupuncture-assisted anesthesia alleviates apparently pain and discomforts during transrectal ultrasound guided prostate biopsy via the perineum in patients and ensures the stability of blood pressure and heart rate. | Zhongguo Zhen Jiu. 2010 Dec;30(12):1015-7. | Heart Rate Blood Pressure | Clinic |
| 21739700 | In the observation group, the pain grades on the left side were lower than that on the right side (P<0.05), and the systolic blood pressure and the heart rate were lower than that in the control group when undergoing the 2nd radiofrequency ablation on the right side and on the left side, respectively (both P<0.05). | Zhongguo Zhen Jiu. 2011 Jun;31(6):543-6. | Heart Rate Blood Pressure | Clinic |
| 22073889 | The dosages of the anesthetics, heart rate (HR), systolic blood pressure (SBP), and bispectral index (BIS) of electroencephalogam during general anesthesia were recorded. | Zhen Ci Yan Jiu. 2011 Oct;36(5):361-5. | Heart Rate Blood Pressure | Clinic |
| 22295830 | The change of ETsev value was recorded, the heart rate (HR) and blood pressure (BP) were observed, and the time from the end of operation to extubation, awake time were recorded adverse events such as restlessness, shivering, postoperative pain, nausea and vomiting, cases of respiratory depression, the analepsia quality, the time of first anus exhaust, the awaking of patient in operation and satisfactory of patients after surgery were recorded so as to evaluate the effect of acupuncture anesthesia. | Zhongguo Zhen Jiu. 2012 Jan;32(1):59-64. | Heart Rate Nausea and Vomiting Blood Pressure Depression | Clinic |
| 22295830 | BP and HR had more stability in group II and group III, the best in group II. | Zhongguo Zhen Jiu. 2012 Jan;32(1):59-64. | Heart Rate Blood Pressure | Clinic |
| 22295830 | It can decrease the dosage of anaesthetic, has a stable effect on HR and BP during the surgery and has a better quality of analepsia. | Zhongguo Zhen Jiu. 2012 Jan;32(1):59-64. | Heart Rate Blood Pressure | Clinic |
| 23163146 | [Contrast study of acupuncture anesthesia and local anesthesia: their effects on the blood pressure and the heart rate in chronic rhinitis patients accompanied inferior turbinate hypertrophy in low temperature radiofrequency ablation]. | Zhongguo Zhong Xi Yi Jie He Za Zhi. 2012 Oct;32(10):1358-60. | Heart Rate Hypothermia Blood Pressure | Clinic |
| 23163146 | OBJECTIVE: To compare the effects of acupuncture anesthesia (AA) and local anesthesia (LA) on the blood pressure (BP) and the heart rate (HR) in chronic rhinitis patients accompanied inferior turbinate hypertrophy in low temperature radiofrequency ablation (RFA). | Zhongguo Zhong Xi Yi Jie He Za Zhi. 2012 Oct;32(10):1358-60. | Heart Rate Hypothermia Blood Pressure | Clinic |
| 23163146 | CONCLUSION: Patients undergoing AA had less fluctuation of the BP and the HR, indicating AA had better analgesic effects. | Zhongguo Zhong Xi Yi Jie He Za Zhi. 2012 Oct;32(10):1358-60. | Analgesic Effect Heart Rate Blood Pressure | Clinic |
| 30369370 | The additional propofol, fentanyl dosage, and changes in heart rate and systolic blood pressure 5 min before and during extubation were compared between the two groups. | J Coll Physicians Surg Pak. 2018 Nov;28(11):817-820. doi: 10.29271/jcpsp.2018.11.817. | Heart Rate Blood Pressure | Clinic |
| 30369370 | There is no statistical difference in heart rate and systolic blood pressure between group A and group B at 5 minutes before and during extubation (p=0.151, 0.660 and 0.734, 0.528, respectively). | J Coll Physicians Surg Pak. 2018 Nov;28(11):817-820. doi: 10.29271/jcpsp.2018.11.817. | Heart Rate Blood Pressure | Clinic |
| 30369370 | CONCLUSION: Combined 2 Hz, 2 Hz/100 Hz acupuncture anesthesia need few anesthetic dosages of propofol and fentanyl to stabilise the patient's blood pressure and heart rate when intubated under general anesthesia; but combined 2 Hz acupuncture anesthesia can reduce IL-4 and IL-10 levels during surgery stress to a greater extent than the latter, and can effectively lower patients' serum IL-4, IL-10 expression after surgery. | J Coll Physicians Surg Pak. 2018 Nov;28(11):817-820. doi: 10.29271/jcpsp.2018.11.817. | Heart Rate Blood Pressure | Clinic |
| 36858243 | The patients' vital signs, including heart rate, blood pressure, and pulse oxygen saturation, were recorded before, during, and after gastroscopy. | Complement Ther Med. 2023 May;73:102936. doi: 10.1016/j.ctim.2023.102936. Epub 2023 Feb 28. | Heart Rate Blood Pressure | Clinic |
| 36858243 | Patients in the EA group had a slower heart rate and lower blood pressure than those in the SA group. | Complement Ther Med. 2023 May;73:102936. doi: 10.1016/j.ctim.2023.102936. Epub 2023 Feb 28. | Heart Rate Blood Pressure | Clinic |
| 22073889 | The dosages of the anesthetics, heart rate (HR), systolic blood pressure (SBP), and bispectral index (BIS) of electroencephalogam during general anesthesia were recorded. | Zhen Ci Yan Jiu. 2011 Oct;36(5):361-5. | Heart Rate Blood Pressure | Clinic |
| 17959591 | RESULTS: The median (range) of the lowest recorded systolic blood pressure was significantly higher in the acupoint group compared with the other groups and that of the non-acupoint group was higher than that of the control group [control, 70 (68-82) mm Hg; acupoint, 94 (84-109) mm Hg; non-acupoint, 81 (70-92) mm Hg: P<0.001]. | Br J Anaesth. 2008 Jan;100(1):78-81. doi: 10.1093/bja/aem306. Epub 2007 Oct 24. | Blood Pressure | Clinic |
| 17959591 | More ephedrine was required to maintain arterial blood pressure in the control and non-acupoint groups. | Br J Anaesth. 2008 Jan;100(1):78-81. doi: 10.1093/bja/aem306. Epub 2007 Oct 24. | Blood Pressure | Clinic |
| 15804591 | RESULTS: When acupuncture analgesia was used, the pulse rate and blood pressure during surgery generally remained stable. | J Craniomaxillofac Surg. 2005 Apr;33(2):118-22. doi: 10.1016/j.jcms.2004.10.003. | Heart Rate Blood Pressure | Clinic |
| 11159266 | Press-acupuncture needles were inserted at the respective auricular areas for 48 h. State anxiety, blood pressure, heart rate, and electrodermal activity were assessed at 30 min, 24 h, and 48 h after insertion. | Anesth Analg. 2001 Feb;92(2):548-53. doi: 10.1097/00000539-200102000-00049. | Heart Rate Anxiety Blood Pressure | Clinic |
| 11159266 | Repeated-measures analysis of variance performed for electrodermal activity, blood pressure, and heart rate demonstrated no group differences (P = ns). | Anesth Analg. 2001 Feb;92(2):548-53. doi: 10.1097/00000539-200102000-00049. | Heart Rate Blood Pressure | Clinic |
| 21346689 | The anesthesiologists were asked to titrate fentanyl to keep the heart rate and blood pressure within 20% of baseline values. | Clin J Pain. 2011 Mar-Apr;27(3):262-7. doi: 10.1097/AJP.0b013e3181fd516c. | Heart Rate Blood Pressure | Clinic |
| 12216602 | The Bispectral Index monitor was used intraoperatively to monitor the hypnotic effect of anaesthetic drugs, and alfentanil was titrated to maintain the blood pressure and pulse rate within +/- 15% of basal values. | Acupunct Med. 2002 Aug;20(2-3):56-65. doi: 10.1136/aim.20.2-3.56. | Heart Rate Blood Pressure | Clinic |
| 26365445 | Acupuncture lowers blood pressure in mild hypertension patients: a randomized, controlled, assessor-blinded pilot trial. | Complement Ther Med. 2015 Oct;23(5):658-65. doi: 10.1016/j.ctim.2015.06.014. Epub 2015 Jul 15. | Blood Pressure | Clinic |
| 26365445 | INTERVENTIONS: Participants were patients with systolic blood pressure (SBP) of 120-159mmHg or diastolic blood pressure (DBP) of 80-99mmHg.Thirty participants were allocated to acupuncture group or untreated control group at a 1:1 ratio. | Complement Ther Med. 2015 Oct;23(5):658-65. doi: 10.1016/j.ctim.2015.06.014. Epub 2015 Jul 15. | Blood Pressure | Clinic |
| 26365445 | CONCLUSION: The results of this study show that acupuncture might lower blood pressure in prehypertension and stage I hypertension, and further RCT need 97 participants in each group. | Complement Ther Med. 2015 Oct;23(5):658-65. doi: 10.1016/j.ctim.2015.06.014. Epub 2015 Jul 15. | Blood Pressure | Clinic |
| 24621826 | In the operating room, standard monitoring (electrocardiogram, BIS, invasive blood pressure, SpO2 using a Datex S/5 Anesthesia Monitor [GE Healthcare, Helsinki, Finland]) was applied, and an intravenous infusion was begun in a peripheral vein and 200 ml colloid solution was infused prior to induction to compensate for overnight fluid loss. | Med Sci Monit. 2014 Mar 12;20:406-12. doi: 10.12659/MSM.890111. | Blood Pressure | Clinic |
| 25047046 | â Vital signs (heart rate and blood pressure) at baseline | Trials. 2014 Jul 21;15:292. doi: 10.1186/1745-6215-15-292. | Heart Rate Blood Pressure | Clinic |
| 25047046 | â Vital signs (heart rate and blood pressure) | Trials. 2014 Jul 21;15:292. doi: 10.1186/1745-6215-15-292. | Heart Rate Blood Pressure | Clinic |
| 25152761 | The following information was recorded during operation: (1) patients' requests for analgesia indicated by raising their hand during the operation as the time of first raising the hand, the number of times the hand was raised for analgesia, the pain visual analogue scale (VAS) values indicated by the patients, and the dosage opium derivative analgesic given; (2) the vital signs such as blood pressure, heart rate, and arterial oxygen partial pressure; and (3) any relevant side effects induced by sedatives and opium derivative analgesic such as nausea, vomit, dizziness, and itching. | Evid Based Complement Alternat Med. 2014;2014:592319. doi: 10.1155/2014/592319. Epub 2014 Jul 23. | Heart Rate Side Effects Nausea and Vomiting Blood Pressure | Clinic |
| 29391879 | NMPN H32020166) were injected intramuscularly 30 min before the anesthesia, and arterial blood gas and blood pressure were monitored. | Oncol Lett. 2018 Jan;15(1):189-194. doi: 10.3892/ol.2017.7262. Epub 2017 Oct 24. | Blood Pressure | Clinic |
| 29391879 | In the perioperative period for subtotal gastrectomy, both the surgery and anesthesia can cause stress leading to increased HR, elevated blood pressure and other changes. | Oncol Lett. 2018 Jan;15(1):189-194. doi: 10.3892/ol.2017.7262. Epub 2017 Oct 24. | Heart Rate Blood Pressure | Clinic |
| 29391879 | However, MAP after anesthesia was lower in experimental group, suggesting that adding acupuncture reduced hypertension responses during surgery and regulate the blood pressure in the recovery period, instead of causing abnormal changes in hemodynamics. | Oncol Lett. 2018 Jan;15(1):189-194. doi: 10.3892/ol.2017.7262. Epub 2017 Oct 24. | Hemodynamics Blood Pressure | Clinic |
| 35647012 | There were no significant abnormalities in vital signs such as operation center rate and blood pressure in all patients. | Front Surg. 2022 May 12;9:901638. doi: 10.3389/fsurg.2022.901638. eCollection 2022. | Blood Pressure | Clinic |
| 36034956 | These indicated that multimodal analgesia combined with auricular application therapy could decrease the degree of physical and mental stress through reducing the preoperative pain, showing that the blood pressure, HR, and anxiety depression were decreased. | Evid Based Complement Alternat Med. 2022 Aug 17;2022:3130956. doi: 10.1155/2022/3130956. eCollection 2022. | Heart Rate Anxiety Blood Pressure Depression | Clinic |
| 22611431 | We defined hypotension as a decrease in systolic blood pressure (SBP) 30% below baseline values or to less than 90xe2x80x89mmHg in the present study. | Evid Based Complement Alternat Med. 2012;2012:727121. doi: 10.1155/2012/727121. Epub 2012 Jan 31. | Blood Pressure | Clinic |
| 22611431 | Baseline systolic blood pressures (SBPs) were similar among these groups (Table 2). | Evid Based Complement Alternat Med. 2012;2012:727121. doi: 10.1155/2012/727121. Epub 2012 Jan 31. | Blood Pressure | Clinic |
| 22611431 | Less ephedrine was required to maintain arterial blood pressure in the 40xe2x80x89Hz group (the control, 8 (0xe2x80x9316) mg; the 2xe2x80x89Hz, 0 (0xe2x80x9320) mg; the 10xe2x80x89Hz, 0 (0xe2x80x938) mg; the 20xe2x80x89Hz, 0 (0xe2x80x9312) mg; the 40xe2x80x89Hz, 0 (0xe2x80x938) mg, P = 0.013). | Evid Based Complement Alternat Med. 2012;2012:727121. doi: 10.1155/2012/727121. Epub 2012 Jan 31. | Blood Pressure | Clinic |
| 22611431 | While administering the same level of electrical stimulation, however, TENS at the specific frequency, 40xe2x80x89Hz, significantly sustained blood pressure. | Evid Based Complement Alternat Med. 2012;2012:727121. doi: 10.1155/2012/727121. Epub 2012 Jan 31. | Blood Pressure | Clinic |
| 23342207 | In addition, pain also stimulates the sympathetic nervous system, which causes an increase in heart rate, blood pressure, sweat production, endocrine hyper-function, and delays in the patient's recovery from surgery. | Korean J Pain. 2013 Jan;26(1):46-50. doi: 10.3344/kjp.2013.26.1.46. Epub 2013 Jan 4. | Heart Rate Endocrinology Blood Pressure | Clinic |
| 23342207 | In the recovery room, the data collected dealt with first time requests of analgesics, the vital signs (such as blood pressure, heart rates, and blood oxygen level), and the VAS score. | Korean J Pain. 2013 Jan;26(1):46-50. doi: 10.3344/kjp.2013.26.1.46. Epub 2013 Jan 4. | Heart Rate Blood Pressure | Clinic |
| 15937559 | The incidence of analgesia-related side effects, time to discharge from the anesthesia recovery room, heart rate and blood pressure were also recorded. | Evid Based Complement Alternat Med. 2005 Jun;2(2):185-189. doi: 10.1093/ecam/neh097. Epub 2005 May 11. | Heart Rate Side Effects Blood Pressure | Clinic |
| 15937559 | Heart rate and blood pressure were taken before and after the AA procedure, 30 min after tracheal intubation, 30 min after tracheal extubation and just before discharge. | Evid Based Complement Alternat Med. 2005 Jun;2(2):185-189. doi: 10.1093/ecam/neh097. Epub 2005 May 11. | Heart Rate Blood Pressure | Clinic |
| 15937559 | Normally distributed continuous data (patient characteristics, pain intensity on VAS-100, duration of general anesthesia and night's sleep, time to discharge, heart rate and blood pressure) were compared using the unpaired Student's t-test. | Evid Based Complement Alternat Med. 2005 Jun;2(2):185-189. doi: 10.1093/ecam/neh097. Epub 2005 May 11. | Heart Rate Blood Pressure | Clinic |
| 15937559 | Heart rate and blood pressure were similar in both groups during the course of monitoring (data not shown). | Evid Based Complement Alternat Med. 2005 Jun;2(2):185-189. doi: 10.1093/ecam/neh097. Epub 2005 May 11. | Heart Rate Blood Pressure | Clinic |
| 24137250 | Once in surgery, the peripheral intravenous infusion was initiated, and noninvasive blood pressure (NIBP), heart rate (HR), oxygen pulse saturation (SpO2) and bispectral index (BIS) were monitored. | Exp Ther Med. 2013 Sep;6(3):699-702. doi: 10.3892/etm.2013.1225. Epub 2013 Jul 16. | Heart Rate Blood Pressure | Clinic |
| 24137250 | Patient characteristics and surgical data are provided in Table I. There were no differences in the arterial blood pressure or HR among the groups prior to, during or after EAS. | Exp Ther Med. 2013 Sep;6(3):699-702. doi: 10.3892/etm.2013.1225. Epub 2013 Jul 16. | Heart Rate Blood Pressure | Clinic |
| 26170873 | Standard monitoring, including electrocardiogram, noninvasive blood pressure, pulse oximetry, and temperature, was used in all patients for the duration of surgery. | Evid Based Complement Alternat Med. 2015;2015:324360. doi: 10.1155/2015/324360. Epub 2015 Jun 11. | Heart Rate Blood Pressure | Clinic |
| 27688791 | Acupuncture Decreases Blood Pressure Related to Hypothalamus Functional Connectivity with Frontal Lobe, Cerebellum, and Insula: A Study of Instantaneous and Short-Term Acupuncture Treatment in Essential Hypertension | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure | Clinic |
| 27688791 | The therapeutic effects of acupuncture in decreasing blood pressure are ambiguous and underlying acupuncture in hypertension treatment has not been investigated. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure | Clinic |
| 27688791 | We found three kinds of results: (1) There was statistical difference in systolic blood pressure in LR3 group after the short-term treatment and before acupuncture. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure | Clinic |
| 27688791 | The Global Burden of Disease study estimates 62% of stroke, 49% of ischemic heart disease, and 14% of other cardiovascular disease can be attributable to mean systolic blood pressure levels >115xe2x80x89mmHg worldwide. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Cardiovascular Blood Pressure | Clinic |
| 27688791 | Blood pressure can be lowered by several classes of drugs and by such lifestyle changes as weight loss, salt intake restriction, and exercises. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure | Clinic |
| 27688791 | However, these therapeutic effects of acupuncture in lowering BP are ambiguous. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure | Clinic |
| 27688791 | Meanwhile, these studies have only observed the efficacy of it; the mechanism underlying acupuncture in high BP treatment has not been investigated. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure | Clinic |
| 27688791 | The blood pressure (BP) of the participants was measured before and after MRI scan. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure | Clinic |
| 27688791 | The BP measurements are performed with mercurial sphygmomanometer (Jiangsu Yuyue Medical Equipment & Supply Co., Ltd.). | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure | Clinic |
| 27688791 | Considering that BP can be easily affected by psychological factors, participants filled out questionnaires for assessments of anxiety (State Trait Anxiety Inventory, STAI). | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Anxiety Blood Pressure | Clinic |
| 27688791 | In the SF-36 survey for QoL, participants in the LR3 group reported the scores before acupuncture of physical functioning (PF, 85.71 xc2xb1 12.69), role physical (RP, 75.00 xc2xb1 36.69), bodily pain (BP, 79.07 xc2xb1 14.85), general health (GH, 50.64 xc2xb1 14.05), vitality (VI, 68.21 xc2xb1 18.57), social functioning (SF, 82.54 xc2xb1 15.54), role emotional (RE, 73.81 xc2xb1 35.03), and mental health (MH, 68.86 xc2xb1 14.98) and the scores after treatment of PF (84.29 xc2xb1 11.74), RP (76.78 xc2xb1 34.62), BP (80.14 xc2xb1 9.46), GH (52.50 xc2xb1 14.29), VI (67.86 xc2xb1 11.56), SF (89.68 xc2xb1 12.68), RE (76.19 xc2xb1 42.22), and MH (66.29 xc2xb1 15.51). | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure Mood | Clinic |
| 27688791 | Participants in the sham group reported the scores before acupuncture of PF (91.79 xc2xb1 5.04), RP (96.43 xc2xb1 9.08), BP (87.14 xc2xb1 9.14), GH (66.21 xc2xb1 11.73), VI (66.79 xc2xb1 10.12), SF (87.30 xc2xb1 16.22), RE (90.48 xc2xb1 27.51), and MH (75.43 xc2xb1 14.19) and the scores after treatment of PF (91.43 xc2xb1 9.89), RP (76.78 xc2xb1 34.62), BP (80.14 xc2xb1 9.46), GH (52.50 xc2xb1 14.29), VI (67.86 xc2xb1 11.56), SF (89.68 xc2xb1 12.68), RE (76.19 xc2xb1 42.22), and MH (66.29 xc2xb1 15.51). | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure | Clinic |
| 27688791 | Participants in the sham group reported the scores before acupuncture of PF (91.79 xc2xb1 5.04), RP (91.07 xc2xb1 25.21), BP (84.68 xc2xb1 12.63), GH (69.00 xc2xb1 18.43), VI (72.86 xc2xb1 14.37), SF (89.68 xc2xb1 15.38), RE (92.86 xc2xb1 26.73), and MH (72.29 xc2xb1 17.08). | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure | Clinic |
| 27688791 | Thus we selected SO and Pa as our seed points to explore functional connectivity changes in brain areas and demonstrate the mechanism of regulation in blood pressure. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure | Clinic |
| 27688791 | The acupuncture effect could modulate the blood pressure, while the functional connectivity map could reflect the modulation in the brain network. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure | Clinic |
| 27688791 | Frontal lobe closely associated with emotions and emotions had relationship with blood pressure. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure Mood | Clinic |
| 27688791 | So we guess frontal lobes could connect with the function of the hypothalamus and indirectly influence the regulation of blood pressure by acupuncture at LR3. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure | Clinic |
| 27688791 | Although the role of cerebellum in cardiovascular center was unclear, there was an animal experiment that showed that the cerebellum had a relationship with nitric oxide synthase activity, indirectly related to blood pressure regulation. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Cardiovascular Blood Pressure | Clinic |
| 27688791 | A case reported resection cerebellar vermis and right cerebellum hemisphere in a cerebellum hemorrhage patient could cause transient orthostatic hypotension, indicating that the cerebellum was involved in blood pressure regulation. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Bleeding Blood Pressure | Clinic |
| 27688791 | In our study, the connectivity between the cerebellum and seed points may reveal that the cerebellum has a role in blood pressure regulation. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure | Clinic |
| 27688791 | (2) We did not use 24-hour ambulatory blood pressure monitoring to monitor the blood pressure. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Blood Pressure | Clinic |
| 28658163 | After entering the operating room, electrocardiogram (ECG), pulse oxygen saturation (SpO2), respiratory rate (R), PetCO2, bispectral index (BIS), and invasive blood pressure of patients were recorded. | Medicine (Baltimore). 2017 Jun;96(26):e7375. doi: 10.1097/MD.0000000000007375. | Heart Rate Blood Pressure | Clinic |
| 28658163 | The entire course of anesthesia was maintained using propofol 4 to 6xe2x80x8amg/(kgh) and remifentanil 0.1 to 0.3xe2x80x8axcexbcg/(kgmin), which sustained the changing of BP and HR within 20% of the initial levels and the BIS value range from 40 to 60. | Medicine (Baltimore). 2017 Jun;96(26):e7375. doi: 10.1097/MD.0000000000007375. | Heart Rate Blood Pressure | Clinic |
| 30425466 | After entering the operating room, electrocardiogram, pulse oxygen saturation, respiratory rate, end-tidal carbon dioxide, bispectral index (BIS), and invasive blood pressure were continuously recorded in the both groups during the peri-operative period. | Clin Interv Aging. 2018 Oct 24;13:2127-2134. doi: 10.2147/CIA.S183698. eCollection 2018. | Heart Rate Blood Pressure | Clinic |
| 30425466 | Blood pressure fluctuation amplitude did not exceed 20% of the base value. | Clin Interv Aging. 2018 Oct 24;13:2127-2134. doi: 10.2147/CIA.S183698. eCollection 2018. | Blood Pressure | Clinic |
| 30425466 | After the surgery, tracheal intubation was removed when patients regained consciousness, tidal volume was 8 mL/kg, and all hemodynamic parameters such as heart rate and blood pressure returned to the normal level. | Clin Interv Aging. 2018 Oct 24;13:2127-2134. doi: 10.2147/CIA.S183698. eCollection 2018. | Heart Rate Blood Pressure | Clinic |
| 33488793 | Upon arrival in the operating room, all patients were continuously monitored with electrocardiography, and the following parameters: Blood pressure, pulse oximetry, pressure of end-tidal carbon dioxide (PETCO2) and bispectral index (BIS) (cat. | Exp Ther Med. 2021 Mar;21(3):184. doi: 10.3892/etm.2021.9615. Epub 2021 Jan 7. | Heart Rate Blood Pressure | Clinic |
| 36098938 | Once the patient entered the operating room, vitals such as electrocardiograph (ECG), arterial blood pressure (ABP), pulse oxygen saturation (SpO2), and bispectral index (BIS) were recorded and monitored. | Pain Ther. 2022 Dec;11(4):1327-1339. doi: 10.1007/s40122-022-00429-2. Epub 2022 Sep 13. | Heart Rate Blood Pressure | Clinic |
| 36098938 | a MAP (mmHg); b HR (beats per minute); MAP mean arterial blood pressure; HR heart rate; T1 before the onset of TEAS, T2 at the establishment of the pneumoperitoneum, T3 1xc2xa0h after the beginning of the operation, T4 the end of the operation, T5 immediately after extubation. | Pain Ther. 2022 Dec;11(4):1327-1339. doi: 10.1007/s40122-022-00429-2. Epub 2022 Sep 13. | Heart Rate Blood Pressure | Clinic |
| 30381011 | Puncture and catheterization of the radial artery were performed after local anesthesia to monitor continuous arterial blood pressure. | Technol Cancer Res Treat. 2018 Jan 1;17:1533033818806477. doi: 10.1177/1533033818806477. | Blood Pressure | Clinic |
| 16173479 | Heart rate, mean arterial blood pressure (MAP), arterial blood oxygen saturation (Spo2) measured by use of pulse oximetry, esophageal body temperature, inspired and expired end-tidal isoflurane concentrations, end-tidal carbon dioxide concentration, and bispectral index (BIS) were monitored. | Am J Vet Res. 2005 Aug;66(8):1364-70. doi: 10.2460/ajvr.2005.66.1364. | Heart Rate Blood Pressure | Mechanism |
| 15633814 | We have previously shown that electroacupuncture (EA) at Shaohai and Neiguan (HT3-PC6) points significantly attenuated stress-induced peripheral responses, including increases in blood pressure, heart rate and plasma catecholamines. | Am J Chin Med. 2004;32(5):795-806. doi: 10.1142/S0192415X04002405. | Heart Rate Blood Pressure | Mechanism |
| 22549008 | Neither herbs nor EA altered heart rate or blood pressure. | J Cardiovasc Pharmacol Ther. 2012 Dec;17(4):403-11. doi: 10.1177/1074248412443310. Epub 2012 May 1. | Heart Rate Blood Pressure | Mechanism |
| 6122716 | This stimulation procedure has previously been shown to evoke naloxone reversible pain threshold elevation and a longlasting blood pressure reduction rats, with maximum reached about 1.5 h after stimulation. | J Neural Transm. 1982;53(2-3):91-100. doi: 10.1007/BF01243400. | Blood Pressure | Mechanism |
| 19553161 | Inhibitory regulation of blood pressure by manual acupuncture in the anesthetized rat. | Auton Neurosci. 2009 Dec 3;151(2):178-82. doi: 10.1016/j.autneu.2009.05.254. Epub 2009 Jun 24. | Blood Pressure | Mechanism |
| 19553161 | Effect of manual acupuncture (twisting; lifting and thrusting; combination of them) at acupoints Nei-guan (PL-6) in the fore limb and Zu-san-li (ST-36) in the hind limb on mean arterial blood pressure was investigated in anesthetized rats. | Auton Neurosci. 2009 Dec 3;151(2):178-82. doi: 10.1016/j.autneu.2009.05.254. Epub 2009 Jun 24. | Blood Pressure | Mechanism |
| 19553161 | During acupuncture treatment mean arterial blood pressure was decreased but fluctuated in intact rats, intensively decreased after vagotomy and completely abolished after spinalization. | Auton Neurosci. 2009 Dec 3;151(2):178-82. doi: 10.1016/j.autneu.2009.05.254. Epub 2009 Jun 24. | Blood Pressure | Mechanism |
| 19553161 | Results suggest that manual acupuncture at either PL-6 or ST-36 can reduce blood pressure in anesthetized rats, and its modulatory site might be supraspinal. | Auton Neurosci. 2009 Dec 3;151(2):178-82. doi: 10.1016/j.autneu.2009.05.254. Epub 2009 Jun 24. | Blood Pressure | Mechanism |
| 26237832 | CONCLUTION: EA could significantly lower blood pressure of stress-induced pre-hypertension rats and affect its gene expression profile in heart. | J Tradit Chin Med. 2015 Jun;35(3):285-94. doi: 10.1016/s0254-6272(15)30099-6. | Blood Pressure | Mechanism |
| 23751198 | Studies have revealed that apelin is a novel multifunctional peptide implicated both in blood pressure (BP) regulation and cardiac function control. | Brain Res Bull. 2013 Aug;97:53-62. doi: 10.1016/j.brainresbull.2013.05.013. Epub 2013 Jun 7. | Blood Pressure | Mechanism |
| 23751198 | Evidence shows that apelin and its receptor (APJ) in the rostral ventrolateral medulla (RVLM) may play an important role in central BP regulation; however, its role is controversial and very few reports have shown the relationship between acupuncture and apelin. | Brain Res Bull. 2013 Aug;97:53-62. doi: 10.1016/j.brainresbull.2013.05.013. Epub 2013 Jun 7. | Blood Pressure | Mechanism |
| 15750372 | Experiment 4: To determine the effects of EA treatment versus immobilization on such stress indicators as heart rate and blood pressure. | J Altern Complement Med. 2005 Feb;11(1):135-42. doi: 10.1089/acm.2005.11.135. | Heart Rate Blood Pressure | Mechanism |
| 35028961 | The purpose of this study was to understand the impact of electroacupuncture on the blood pressure of SHRs and the impact on metabolites in the renal cortex, looking for potential differential metabolites and then proceeding to the next step of exploratory research. | Biomed Chromatogr. 2022 May;36(5):e5338. doi: 10.1002/bmc.5338. Epub 2022 Mar 21. | Blood Pressure Kidney | Mechanism |
| 35028961 | The results showed that electroacupuncture can significantly reduce the blood pressure of SHRs. | Biomed Chromatogr. 2022 May;36(5):e5338. doi: 10.1002/bmc.5338. Epub 2022 Mar 21. | Blood Pressure | Mechanism |
| 26566622 | OBJECTIVES: To investigate the effect of electroacupuncture (EA) at LR3 on blood pressure (BP) and cardiovascular remodelling and hypertrophy in male spontaneously hypertensive rats (SHRs). | Acupunct Med. 2016 Jun;34(3):201-8. doi: 10.1136/acupmed-2015-010782. Epub 2015 Nov 13. | Cardiovascular Blood Pressure | Mechanism |
| 26566622 | BP was measured on day 3 and day 19. | Acupunct Med. 2016 Jun;34(3):201-8. doi: 10.1136/acupmed-2015-010782. Epub 2015 Nov 13. | Blood Pressure | Mechanism |
| 26566622 | RESULTS: By day 3, the systolic BP, mean BP, and diastolic BP in the untreated SHRs increased from 169.5+/-14, 131.6+/-14, and 112.2+/-15 mm Hg (at baseline) to 179.6+/-1, 137.6+/-4, and 118.7+/-5 mm Hg, respectively (p<0.001 vs control group). | Acupunct Med. 2016 Jun;34(3):201-8. doi: 10.1136/acupmed-2015-010782. Epub 2015 Nov 13. | Blood Pressure | Mechanism |
| 26566622 | BP in the SHR+LR3 rats was approximately 15 mm Hg lower than the SHR and SHR+sham groups (p<0.05). | Acupunct Med. 2016 Jun;34(3):201-8. doi: 10.1136/acupmed-2015-010782. Epub 2015 Nov 13. | Blood Pressure | Mechanism |
| 26566622 | CONCLUSIONS: EA at LR3 reduced BP and had positive effects on markers of cardiac apoptosis and hypertrophy in a rat model of hypertension. | Acupunct Med. 2016 Jun;34(3):201-8. doi: 10.1136/acupmed-2015-010782. Epub 2015 Nov 13. | Blood Pressure | Mechanism |
| 28793984 | We aimed to explore the effects of manual acupuncture (MA) with manual stimulation on blood pressure (BP) and urine metabolites in the spontaneously hypertensive rat (SHR) model of hypertension. | Acupunct Med. 2017;35(5):374-382. doi: 10.1136/acupmed-2016-011170. Epub 2017 Aug 9. | Blood Pressure | Mechanism |
| 28793984 | METHODS: After adaptive feeding (with a standard laboratory diet and distilled water) for 1 week, five normotensive Wistar Kyoto (WKY) rats with normal BP formed the control group. | Acupunct Med. 2017;35(5):374-382. doi: 10.1136/acupmed-2016-011170. Epub 2017 Aug 9. | Blood Pressure | Mechanism |
| 28793984 | BP was measured pre- and post-acupuncture in all groups and urinary metabolic profiles were investigated using metabonomics methods based on (1)H nuclear magnetic resonance (NMR) spectroscopy coupled with principal component analysis, partial least squares discriminant analysis, and orthogonal to partial least squares discriminant analysis. | Acupunct Med. 2017;35(5):374-382. doi: 10.1136/acupmed-2016-011170. Epub 2017 Aug 9. | Blood Pressure | Mechanism |
| 28793984 | Furthermore, systolic and diastolic BP, mean arterial pressure and heart rate were significantly reduced after acupuncture. | Acupunct Med. 2017;35(5):374-382. doi: 10.1136/acupmed-2016-011170. Epub 2017 Aug 9. | Heart Rate Blood Pressure | Mechanism |
| 28793984 | CONCLUSIONS: Acupuncture may decrease BP in SHRs by improving the metabolic disorder associated with hypertension. | Acupunct Med. 2017;35(5):374-382. doi: 10.1136/acupmed-2016-011170. Epub 2017 Aug 9. | Blood Pressure | Mechanism |
| 34981123 | DEPs was classified according to GO annotation into three categories: Biological process (BP), cellular component (CC), and molecular function (MF). | Biosci Rep. 2022 Jan 28;42(1):BSR20212248. doi: 10.1042/BSR20212248. | Blood Pressure | Mechanism |
| 34981123 | Cluster analysis was carried out to compare the functional correlation of DEPs in the MCG and ATG groups, the GO enrichment analysis demonstrated that DEPs were associated with the single organism processes and cellular process in the BP (Figure 4B); organelle and cell in CC (Figure 4C); protein binding and catalytic activity in MF (Figure 4D). | Biosci Rep. 2022 Jan 28;42(1):BSR20212248. doi: 10.1042/BSR20212248. | Blood Pressure | Mechanism |
| 34981123 | Pathway analysis is the most direct and basic method to understand the BP of disease-causing cells and to define potential mechanisms of intervention systematically and comprehensively. | Biosci Rep. 2022 Jan 28;42(1):BSR20212248. doi: 10.1042/BSR20212248. | Blood Pressure | Mechanism |
| 22984478 | Blood pressure was monitored over 7 days. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | Hypertension is a multifactorial condition characterized by systolic blood pressure (SBP) of â¥140 mmHg or diastolic blood pressure (DBP) of â¥90 mmHg. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | Despite the recent increase in public awareness of hypertension, only 78% of hypertensive patients were aware of their condition; 68% were using antihypertensive drugs; and 64% of those treated had their blood pressure controlled. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | Although there is some discrepancy between the reports, the majority of them indicate that acupuncture of traditional acupoints causes a significant decrease in blood pressure, while acupuncture at sham points does not. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | However, the long-term effect and elucidation of the mechanisms through which acupuncture lowers blood pressure has not been reported. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | Additionally, as hypertension is a multifactorial condition and acupuncture results in a multitude of in vivo changes, we believe that acupuncture will lower blood pressure through modulation of multiple biochemical and molecular pathways. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | The animals were given food and water ad libitum for 3 days, and were acclimatized to handling by the researchers and BP-measuring conditions for 1 week prior to acupuncture treatments. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | Measurement of Blood Pressure | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | Blood pressure measurements were performed by two experienced technicians directly after acupuncture. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | SBP was measured non-invasively by the tailcuff method after at least a 5-min resting period using the BP-6A blood pressure measuring system from Chengdu TME Technology Co. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | The ventral portion of each rat was placed on the heat pad, while the BP measurement cuffs were put in place. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | Two BP-6A measuring systems were used so that blood pressure measurements could be done concurrently with acupuncture. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | The results of between-day comparison in each group are as follows: compared with the 1st day, the SBP of Taichong group decreased significantly on the 2nd day (P<0.01); but on the 3rd and 4th day, the SBP was increased again (P>0.05), and then began to decrease at the 5th day (P<0.01), until the 6th and 7th day, at which point the level of SBP remained stable (P<0.01, Figure 2), suggesting that acupuncture at Taichong point begin to stabilize the blood pressure level since the 5th day. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | Although there has been some discordance as to the efficacy of acupuncture in hypertension, our results indicate that acupuncture at the Taichong (LR3) acupoint does alleviate high blood pressure due to essential hypertension, though this treatment alone is not able to bring blood pressure down to normal levels. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | Our study, like most others, reports the short-term effect of acupuncture (directly following treatment) on blood pressure. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | Due to the proteomic nature of our study and the necessary euthanasia of the rats, the long-term effect of acupuncture on blood pressure regrettably could not be studied. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | To avoid the interfering effect of female sex hormones on blood pressure, we have chosen male animals in this study. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | Studies have revealed sex hormones play a role in the regulation of blood pressure and development of hypertension. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | As stabilization of blood pressure in the Taichong group takes 5 days, the lag time between acupuncture treatment and stabilization of blood pressure suggests activation of specific metabolic pathways, causing changes at the protein expression level that contribute to the alteration at the cellular level. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | Changes at the cellular level eventually induce reduction in blood pressure at the systemic level. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | An up-regulation of oxidative stress enzymes and a decrease of oxidative stress may have multiple effects through which blood pressure is modulated. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | In addition, paraventricular nucleus (PVN) of the hypothalamus plays a major role in autonomic and neuroendocrine regulation of blood pressure and body fluid homeostasis. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | Since multiple regions/nuclei of the medulla are involved in blood pressure regulation, we collected the whole medulla for our study. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | To examine whether the proteins located in specific nuclei of the medulla are related to blood pressure modification by acupuncture, we have conducted a preliminary immunohistochemical study and shown altered MBP and synapsin I expression in some specific regions (e.g. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Immunity Blood Pressure | Mechanism |
| 22984478 | Although acupuncture does not directly lower blood pressure to normal level in SHRs, the resulting up-regulation of ALDH2 suggests that it could be used as a complementary treatment to modern medicine to increase the efficacy of certain nitric oxide based drugs. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | Studies have shown that double knockout (synapsin-1 and synapsin-2) mice have a lower basal blood pressure than normal mice, and additional studies from the same group showed that the same double knockout mice did not respond with progressive hypertension to treatment with cyclosporine A as is normally seen in mice, indicating that the synapsins play an integral role in control of blood pressure. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 22984478 | A number of epidemiological and clinical data suggests that antioxidant-rich diets or natural antioxidants reduce blood pressure and cardiovascular risk, and animal studies have also shown the antihypertensive activity of antioxidants. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Cardiovascular Blood Pressure | Mechanism |
| 22984478 | In conclusion, this study is the first to report the complete protein expression profile of acupuncture on SHRs, and has shown the potential involvement of oxidative stress as a partial mechanism in reduction of blood pressure by acupuncture therapy. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Blood Pressure | Mechanism |
| 25282142 | The Directed Acyclic Graph (DAG) of the enriched Gene Ontology (GO) biological process (BP) categories and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of differentially expressed proteins were performed using the bioinformatics tool WebGestalt (WEB-based GEne SeT AnaLysis Toolkit, http://bioinfo.vanderbilt.edu/webgestalt/) to highlight potential biological processes affected by acupuncture. | BMC Complement Altern Med. 2014 Oct 5;14:375. doi: 10.1186/1472-6882-14-375. | Blood Pressure | Mechanism |
| 25282142 | Acupuncture regulates autonomic nerve system functions (e.g., modulates blood pressure, heart rate, and sphincter intensity), immune system and inflammatory pathways, and endocrine system functions, such as the release of endorphins and NO, under different pathological conditions. | BMC Complement Altern Med. 2014 Oct 5;14:375. doi: 10.1186/1472-6882-14-375. | Immunity Heart Rate Endocrinology Blood Pressure | Mechanism |
| 32796318 | Briefly, fragmentation of 200 ng of gDNA was performed using the Covaris LE220 focused-ultrasonicator (Covaris, Woburn, MA) to a target peak size of 400 to 700 bp. | Pain. 2021 Feb 1;162(2):514-530. doi: 10.1097/j.pain.0000000000002031. | Blood Pressure | Mechanism |
| 32796318 | Paired-end sequencing reads (151 bp) generated from WGBS were verified of their sequence quality with Fast QC (version 0.11.7). | Pain. 2021 Feb 1;162(2):514-530. doi: 10.1097/j.pain.0000000000002031. | Blood Pressure | Mechanism |
| 29123119 | A previous study showed that acupoint stimulation activates opioid receptors in the RVLM, a central site for the regulation of blood pressure, and suppresses visceral reflex stimulation-induced hypertension. | Sci Rep. 2017 Nov 9;7(1):15214. doi: 10.1038/s41598-017-14359-z. | Blood Pressure | Mechanism |
| 29123119 | Immobilization-induced hypertension and measurement of blood pressure | Sci Rep. 2017 Nov 9;7(1):15214. doi: 10.1038/s41598-017-14359-z. | Blood Pressure | Mechanism |
| 29123119 | Systolic blood pressure was measured non-invasively with a tail cuff blood pressure monitor (Model 47, IITC). | Sci Rep. 2017 Nov 9;7(1):15214. doi: 10.1038/s41598-017-14359-z. | Blood Pressure | Mechanism |
| 29123119 | The mean of two readings was taken at each blood pressure measurement. | Sci Rep. 2017 Nov 9;7(1):15214. doi: 10.1038/s41598-017-14359-z. | Blood Pressure | Mechanism |
| 24722278 | Blood pressure and ECG were monitored throughout the operation. | PLoS One. 2014 Apr 10;9(4):e94604. doi: 10.1371/journal.pone.0094604. eCollection 2014. | Blood Pressure | Mechanism |
| 24722278 | In brief, the protein-chromatin lysate was fragmented to a length between 200 and 1,000 bp by sonication (Diagenode). | PLoS One. 2014 Apr 10;9(4):e94604. doi: 10.1371/journal.pone.0094604. eCollection 2014. | Blood Pressure | Mechanism |
| 24722278 | Primers were designed to amplify the promoter region between 500 bp upstream and 1000 bp downstream of TTS at the VEGF gene. | PLoS One. 2014 Apr 10;9(4):e94604. doi: 10.1371/journal.pone.0094604. eCollection 2014. | Blood Pressure | Mechanism |
| 24722278 | Our results showed that the diastolic and systolic blood pressure were both decreased after ligation (Fig.S1), the ST segment was noticeably elevated in both MI and EA groups in 30 min, and the representative necrotic Q-waves were appeared 1 day after operation, indicating the success of the MI model (Fig.1A). | PLoS One. 2014 Apr 10;9(4):e94604. doi: 10.1371/journal.pone.0094604. eCollection 2014. | Blood Pressure | Mechanism |
| 24722278 | Our results indicated that H3K9ace occupancy at â500 bp to +200 bp region was augmented prominently by EA treatment (P<0.01), suggesting a direct modification of H3K9 acetylation at the VEGF gene. | PLoS One. 2014 Apr 10;9(4):e94604. doi: 10.1371/journal.pone.0094604. eCollection 2014. | Blood Pressure | Mechanism |
| 23173601 | As we focused on laparotomy induced pain, indexes such as blood pressure, heart rate and breath during surgery were not included in the present study. | BMC Complement Altern Med. 2012 Nov 22;12:225. doi: 10.1186/1472-6882-12-225. | Heart Rate Blood Pressure | Mechanism |
| 30089868 | Activation of mTOR contributes to the phosphorylation of two major substrates downstream, ribosomal protein S6 kinase (p70S6K) and translation repressor protein 4E-binding protein 1 (4E-BP-1); activation of these control elements induces protein translation. | Sci Rep. 2018 Aug 8;8(1):11864. doi: 10.1038/s41598-018-30337-5. | Blood Pressure | Mechanism |
| 30089868 | The proteins assessed were p-extracellular signal-regulated kinase (ERK) forms 1 and 2, p-Akt, p-mTOR, p-p70S6K, p-4E-BP-1, and p-CREB. | Sci Rep. 2018 Aug 8;8(1):11864. doi: 10.1038/s41598-018-30337-5. | Blood Pressure | Mechanism |
| 30089868 | Western blot analysis of protein expression levels of (A) ERK, (B) Akt, (C) mTOR, (D) p70S6K, (E) 4E-BP-1 and (F) CREB in the hippocampus. | Sci Rep. 2018 Aug 8;8(1):11864. doi: 10.1038/s41598-018-30337-5. | Blood Pressure | Mechanism |
| 30089868 | Phosphorylation of mTOR also hyperphosphorylates the downstream protein 4E-BP-1, thereby decreasing the interaction with elF4E and promote protein translation. | Sci Rep. 2018 Aug 8;8(1):11864. doi: 10.1038/s41598-018-30337-5. | Blood Pressure | Mechanism |
| 30089868 | As reported for other rodent depression models, we observed that SPS decreased the phosphorylation levels of upstream proteins such as pAkt and pERK as well as mTOR and its downstream p4E-BP-1 and p70S6K in the hippocampus. | Sci Rep. 2018 Aug 8;8(1):11864. doi: 10.1038/s41598-018-30337-5. | Blood Pressure Depression | Mechanism |
| 30089868 | In parallel, mTOR hyperphosphorylates 4E-BP-1, reducing its interaction with eIF4E. | Sci Rep. 2018 Aug 8;8(1):11864. doi: 10.1038/s41598-018-30337-5. | Blood Pressure | Mechanism |
| 30089868 | Together, released of eIF4E from 4E-BP-1 disinhibit protein translation, producing more synaptic proteins such as PSD95, Syn1 and GluR1, as well as BDNF. | Sci Rep. 2018 Aug 8;8(1):11864. doi: 10.1038/s41598-018-30337-5. | Blood Pressure | Mechanism |
| 30089868 | Moreover, we found that acupuncture treatment alleviated the decreased levels of hippocampal mTOR-related signaling proteins, including BDNF and phosphorylated Akt, ERK, p70S6K, and 4E-BP-1. | Sci Rep. 2018 Aug 8;8(1):11864. doi: 10.1038/s41598-018-30337-5. | Blood Pressure | Mechanism |
| 30089868 | The primary antibodies: p-Akt (1:1000, Cell Signaling Technology, #4058), total Akt (1:1000, Cell Signaling Technology, #4691), p-ERK1/2 (1:3000, Cell Signaling Technology, #4370), total ERK1/2 (1:3000, Cell Signaling Technology, #9102), p-mTOR (1:500, Cell Signaling Technology, #2971), total mTOR (1:500, Cell Signaling Technology, #2983), p-CREB (1:500, Cell Signaling Technology, #9198), total CREB (1:500, Cell Signaling Technology, #9197), p-4E-BP-1 (1:500, Cell Signaling Technology, #9456), p-p70S6K (1:500, Cell Signaling Technology, #9204), p-Syn1 (1:500, Cell Signaling Technology, #88246), p-GluR1 (1:500, Cell Signaling Technology, #8084), p-PSD95 (1:500, Cell Signaling Technology, #45737), total PSD95 (1:500, Cell Signaling Technology, #3409), BDNF (1:300, Santa Cruz Biotechnology, sc-546), and β-actin (1:30000, Sigma-Aldrich, A1978). | Sci Rep. 2018 Aug 8;8(1):11864. doi: 10.1038/s41598-018-30337-5. | Blood Pressure | Mechanism |
| 26991319 | Amplified DNA sizes were 497 bp and 409 bp for TNF-α and actin, respectively. | PLoS One. 2016 Mar 18;11(3):e0151882. doi: 10.1371/journal.pone.0151882. eCollection 2016. | Blood Pressure | Mechanism |
| 15046638 | How systemic circulatory changes affect OBF was evaluated by continuous recording of the blood pressure. | Reprod Biol Endocrinol. 2004 Mar 26;2:16. doi: 10.1186/1477-7827-2-16. | Blood Pressure Circulation | Mechanism |
| 15046638 | High-frequency EA at 6 mA significantly decreased OBF and mean arterial blood pressure (MAP) in the Control group compared to baseline. | Reprod Biol Endocrinol. 2004 Mar 26;2:16. doi: 10.1186/1477-7827-2-16. | Blood Pressure | Mechanism |
| 15046638 | In addition, the contribution of systemic circulatory changes to OBF was evaluated by continuous recording of the blood pressure. | Reprod Biol Endocrinol. 2004 Mar 26;2:16. doi: 10.1186/1477-7827-2-16. | Blood Pressure Circulation | Mechanism |
| 15046638 | Mean arterial blood pressure (MAP) was continuously recorded from a catheter in the right femoral artery and was maintained above 90 mm Hg (systolic) by administration of 4% Ficoll 70 (Pharmacia Fine Chemicals, Uppsala, Sweden). | Reprod Biol Endocrinol. 2004 Mar 26;2:16. doi: 10.1186/1477-7827-2-16. | Blood Pressure | Mechanism |
| 15046638 | The depth of anesthesia was continuously monitored by observing movements, blood pressure and heart rate. | Reprod Biol Endocrinol. 2004 Mar 26;2:16. doi: 10.1186/1477-7827-2-16. | Heart Rate Blood Pressure | Mechanism |
| 32956833 | Immobilization stress-induced hypertension (IMH) and the measurement of systolic blood pressure | Brain Behav Immun. 2021 Jan;91:683-694. doi: 10.1016/j.bbi.2020.08.016. Epub 2020 Sep 18. | Blood Pressure | Mechanism |
| 32956833 | Systolic blood pressure was measured non-invasively with a tail cuff blood pressure monitor (Model 47, IITC Inc., USA). | Brain Behav Immun. 2021 Jan;91:683-694. doi: 10.1016/j.bbi.2020.08.016. Epub 2020 Sep 18. | Blood Pressure | Mechanism |
| 32956833 | The mean of two readings was used for each blood pressure measurement. | Brain Behav Immun. 2021 Jan;91:683-694. doi: 10.1016/j.bbi.2020.08.016. Epub 2020 Sep 18. | Blood Pressure | Mechanism |
| 32956833 | After the initiation of restraint, the systolic blood pressure (BP) gradually increased over the next 2 h (two-way repeated ANOVA; group F(1,5) = 116.31, p < 0.001; time F(12,60) = 16.725, p < 0.001; interaction F(12,60) = 15.879, p < 0.001; Fig. | Brain Behav Immun. 2021 Jan;91:683-694. doi: 10.1016/j.bbi.2020.08.016. Epub 2020 Sep 18. | Blood Pressure | Mechanism |
| 32956833 | Acupuncture at Neuro-Sps near the wrist, but not the nearby points SI5, prevented or reduced the elevation of blood pressure following restraint (Fig. | Brain Behav Immun. 2021 Jan;91:683-694. doi: 10.1016/j.bbi.2020.08.016. Epub 2020 Sep 18. | Blood Pressure | Mechanism |
| 32956833 | In restrained rats, systolic blood pressure was significantly elevated, reaching a level consistent with hypertension of over 150 mmHg within 1 h, compared to that in un-restrained control rats (Control). | Brain Behav Immun. 2021 Jan;91:683-694. doi: 10.1016/j.bbi.2020.08.016. Epub 2020 Sep 18. | Blood Pressure | Mechanism |
| 32956833 | Effect of subcutaneous SP at Neuro-Sps on blood pressure in IMH rats. | Brain Behav Immun. 2021 Jan;91:683-694. doi: 10.1016/j.bbi.2020.08.016. Epub 2020 Sep 18. | Blood Pressure | Mechanism |
| 32956833 | Effect of the subcutaneous injection of capsaicin into Neuro-Sps on blood pressure in IMH rats. | Brain Behav Immun. 2021 Jan;91:683-694. doi: 10.1016/j.bbi.2020.08.016. Epub 2020 Sep 18. | Blood Pressure | Mechanism |
| 31600836 | Electrical stimulation of the CPu and Acb causes changes in blood pressure, heart rate, and respiratory rate. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Heart Rate Blood Pressure | Mechanism |
| 36003380 | The validated libraries were used for sequencing on the Illumina HiSeq 2500 platform of BGI America (Cambridge, MA), following the standard pipelines of Illumina and generating 2 Ã 250 bp paired-end reads. | Front Immunol. 2022 Aug 8;13:955581. doi: 10.3389/fimmu.2022.955581. eCollection 2022. | Blood Pressure | Mechanism |
| 30662282 | As shown in Figures 5 and 6, the horizontal axis of the graph represents the three categories (biological process [BP], molecular function [MF], and cellular component [CC] categories), while the vertical axis represents the number of significant proteins. | J Pain Res. 2019 Jan 7;12:283-298. doi: 10.2147/JPR.S185916. eCollection 2019. | Blood Pressure | Mechanism |
| 30662282 | The top three enriched BP categories were system process proteins (51 proteins, richFactor =0.16, CG/MG; 46 proteins, richFactor =0.14, DG/MG), muscle system process proteins (43 proteins, richFactor =0.25, CG/MG; 37 proteins, richFactor =0.22, DG/MG), and muscle contraction proteins (41 proteins, richFactor =0.28, CG/MG; 36 proteins, richFactor =0.24, DG/MG). | J Pain Res. 2019 Jan 7;12:283-298. doi: 10.2147/JPR.S185916. eCollection 2019. | Blood Pressure | Mechanism |
| 30662282 | Notes: In terms of BP, the top three enriched categories were: system process proteins (51 proteins, richFactor =0.16), muscle system process proteins (43 proteins, richFactor =0.25), and muscle contraction proteins (41 proteins, richFactor =0.28). | J Pain Res. 2019 Jan 7;12:283-298. doi: 10.2147/JPR.S185916. eCollection 2019. | Blood Pressure | Mechanism |
| 30662282 | Abbreviations: BP, biological process; CC, cellular component; CG, control group; GO, gene ontology; MF, molecular function; MG, model group. | J Pain Res. 2019 Jan 7;12:283-298. doi: 10.2147/JPR.S185916. eCollection 2019. | Blood Pressure | Mechanism |
| 30662282 | Notes: In terms of BP, the top three enriched categories were system process proteins (46 proteins, richFactor =0.14), muscle system process proteins (37 proteins, richFactor =0.22), and muscle contraction proteins (36 proteins, richFactor =0.24). | J Pain Res. 2019 Jan 7;12:283-298. doi: 10.2147/JPR.S185916. eCollection 2019. | Blood Pressure | Mechanism |
| 30662282 | Abbreviations: BP, biological process; CC, cellular component; DG, dry needling of MTrPs group; GO, gene ontology; MF, molecular function; MG, model group. | J Pain Res. 2019 Jan 7;12:283-298. doi: 10.2147/JPR.S185916. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | It has been reported that acupuncture at Taichong acupoints (LR3) decreases high blood pressure in spontaneously hypertensive rats. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | In this study, rats were treated with 2 weeks of acupuncture followed by regular recording of blood pressure (BP). | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | BP measurements showed that acupuncture significantly decreased systolic blood pressure (SBP), mean arterial pressure (MAP), and heart rate (HR). | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Heart Rate Blood Pressure | Mechanism |
| 30906419 | Among all brain regions, the rostral ventrolateral medulla (RVLM) is a critical node of blood pressure (BP) control. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | Previous studies observed BP changes when RVLM neurons are bulk activated or inhibited with amino acids or GABA-mimetic compounds, while firing RVLM neurons with appropriate optogenetic or pharmacogenetic actuators could also produce the effects of BP fluctuation. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | BP changes resulting primarily from variations in sympathetic nerve activity are presumably mediated by monosynaptic projections from the RVLM to preganglionic sympathetic neurons. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | Previous clinical trials have indicated that acupuncture can effectively lower the systolic blood pressure (SBP) and diastolic blood pressure (DBP) in hypertensive patients. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | Our team has recently demonstrated that high BP and oxidative stress in the RVLM of spontaneously hypertensive rats (SHRs) were decreased by acupuncture. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | BP and Heart Rate Measurements | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Heart Rate Blood Pressure | Mechanism |
| 30906419 | To investigate the effects of acupuncture on BP and sympathetic activity, a floating polyethylene catheter was inserted into the lower abdominal aorta, and the transmitter was implanted into the abdominal cavity. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | For BP and HR analysis, the system measured the mean values of these parameters for 2 hours in each measurement. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Heart Rate Blood Pressure | Mechanism |
| 30906419 | The BP and HR data were analyzed by 2-way ANOVA with repeated measures, and followed by the Scheffe multiple-range test for post hoc assessment of individual means. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Heart Rate Blood Pressure | Mechanism |
| 30906419 | The Effects of Acupuncture on BP and HR in Rats | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Heart Rate Blood Pressure | Mechanism |
| 30906419 | But the normal BP and HR of WKYs were not altered by acupuncture. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Heart Rate Blood Pressure | Mechanism |
| 30906419 | In stress-induced prehypertension model, needling at LR3 and Quchi (LI11) could reduce BP by targeting the gene expression of heart and hypothalamus. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | Consistent with previous studies, we selected LR3 and found that acupuncture significantly decreased the SBP, MBP, and HR in SHRs compared with WKYs, without any impact on normal BP. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Heart Rate Blood Pressure | Mechanism |
| 30906419 | Moreover, some imaging studies showed that the effects of acupuncture on BP might involve altered cerebral or urinary metabolism. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | The BP Regulation of Acupuncture Might Be Involved in Multiple Gene Clusters | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | Cluster analysis was used to find out the transcriptional evidence of acupuncture's effect on BP. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | This congruency suggests that the balance of some genetic subgroups, but not single gene, participates in maintaining blood pressure and could be regulated by acupuncture at LR 3. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | Glutathione is a major intracellular thiol-disulfide redox cofactor for many antioxidant enzymes and is considered to be a key node in combating increased blood pressure, not only for its capacity of free radical scavenging, but also by controlling nitric oxide (NO) bioavailability. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | They increase, prior to the BP rise, and enhance the survival of noradrenergic neurons hyperinnervated by sympathetic nerves. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | A miRNA study profiled that acupuncture could restore high BP through activating neurotrophin signaling pathway. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | For example, as an angiogenic factor, vascular endothelial growth factor-A (VEGFA) regulates BP by promoting vasodilation. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | Ptgs1 is engaged in regulation of BP by encoding cyclooxygenase-1 (COX-1). | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | During the course of pathological changes, acupuncture could attenuate BP by protecting endothelial function from oxidative stress in SHRs. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | First, increased BP is commonly accompanied by risk factors such as insulin resistance or dyslipidemia especially in SHRs and essential hypertension in human. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | Third, NOX4 upregulation would induce the unfolded protein response (UPR), causing endoplasmic reticulum (ER) stress in vascular smooth muscle cells, which was mentioned frequently in the last few years for its role in BP elevation and vascular injury in SHR. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | We are cognizant that the expression of these genes might provide some small pieces of puzzle for mechanism of blood pressure maintaining and for mechanism of acupuncture therapeutic effects too. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Blood Pressure | Mechanism |
| 30906419 | (a) Systolic blood pressure; (b) mean arterial pressure; (c) heart rate. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Heart Rate Blood Pressure | Mechanism |
| 25206407 | ischemic control and M15 groups; bP < 0.05, vs. | Neural Regen Res. 2013 Apr 25;8(12):1132-8. doi: 10.3969/j.issn.1673-5374.2013.12.008. | Blood Pressure | Mechanism |
| 25206407 | ischemic control, M15, M40-non-TTI and M60-non-TTI groups; bP < 0.01, vs. | Neural Regen Res. 2013 Apr 25;8(12):1132-8. doi: 10.3969/j.issn.1673-5374.2013.12.008. | Blood Pressure | Mechanism |
| 30151295 | Scolopendra pharmacopuncture is usually used to treat entrapment neuropathy and inflammatory disease; it also has anti-convulsive, analgesic, anti-inflammatory, and anti-tumor effects and can lower blood pressure. | J Pharmacopuncture. 2017 Dec;20(4):257-264. doi: 10.3831/KPI.2017.20.031. Epub 2017 Sep 25. | Blood Pressure | Mechanism |
| 25206746 | The band size in the marker lane, from top to bottom, is 2,000 bp, 1,000 bp, 750 bp, 500 bp, 250 bp, and 100 bp. | Neural Regen Res. 2014 Jan 1;9(1):76-83. doi: 10.4103/1673-5374.125333. | Blood Pressure | Mechanism |
| 25206697 | A 219-bp fragment of brain-derived neurotrophic factor mRNA and a 242-bp fragment of glial cell line-derived neurotrophic factor mRNA were obtained by PCR amplification (Figure 1). | Neural Regen Res. 2013 Feb 25;8(6):540-9. doi: 10.3969/j.issn.1673-5374.2013.06.007. | Blood Pressure | Mechanism |
| 25206697 | M: Size markers (600, 500, 400, 300, 200, 100 bp from top to bottom); 1, 5, 9: blank group; 2, 6, 10: sham-surgery group; 3, 7, 11: model group; 4, 8, 12: electroacupuncture group. | Neural Regen Res. 2013 Feb 25;8(6):540-9. doi: 10.3969/j.issn.1673-5374.2013.06.007. | Blood Pressure | Mechanism |
| 30872987 | Robotic or manual twisting of acupuncture needles effectively suppressed cocaine-induced hyperactivity, elevated systemic blood pressure or mustard oil-induced visceral pain in rats. | Front Neurosci. 2019 Feb 20;13:110. doi: 10.3389/fnins.2019.00110. eCollection 2019. | Visceral Pain Blood Pressure | Mechanism |
| 30872987 | Immobilization-Induced Hypertension and Measurement of Blood Pressure | Front Neurosci. 2019 Feb 20;13:110. doi: 10.3389/fnins.2019.00110. eCollection 2019. | Blood Pressure | Mechanism |
| 30872987 | Systolic blood pressure was measured noninvasively with a tail cuff blood pressure monitor (Model 47, IITC). | Front Neurosci. 2019 Feb 20;13:110. doi: 10.3389/fnins.2019.00110. eCollection 2019. | Blood Pressure | Mechanism |
| 30872987 | The mean of the two readings was taken at each blood pressure measurement. | Front Neurosci. 2019 Feb 20;13:110. doi: 10.3389/fnins.2019.00110. eCollection 2019. | Blood Pressure | Mechanism |
| 30872987 | Bupivacaine, but not collagenase, inhibited the acupuncture effects of PC6 (D) on elevated systolic blood pressure in rats (E,F) Representative pulse signals measured from tail (E) *p < 0.05 vs. | Front Neurosci. 2019 Feb 20;13:110. doi: 10.3389/fnins.2019.00110. eCollection 2019. | Heart Rate Blood Pressure | Mechanism |
| 30872987 | The acupoint stimulation activates opioid receptors in the rostral ventrolateral medulla, a central site regulating blood pressure (Sved et al.,), and suppresses stimulation-induced hypertension (Tjen-a-Looi et al.,; Kim et al.,). | Front Neurosci. 2019 Feb 20;13:110. doi: 10.3389/fnins.2019.00110. eCollection 2019. | Blood Pressure | Mechanism |
| 29853959 | Blood pressure (BP) measurement and PET were performed after the first needling and the 7-day treatment period. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Blood Pressure | Mechanism |
| 29853959 | Hypertension is characterised by a sustained increase in arterial BP and is usually associated with heart disease, peripheral vascular disease, and stroke. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Blood Pressure | Mechanism |
| 29853959 | Acupuncture is a complementary approach to BP management. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Blood Pressure | Mechanism |
| 29853959 | In recent years, many randomized controlled trials have demonstrated that needling at LR3 regulates essential hypertension in patients, and animal experiments have also indicated that moderate stimulation of LR3 has a significant effect on BP of SHRs. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Blood Pressure | Mechanism |
| 29853959 | Yet, the exact mechanisms underlying effects of acupuncture on BP remain unclear. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Blood Pressure | Mechanism |
| 29853959 | Acupuncture stimulation of specific acupoints such as LR3 affects the cardiovascular system and accordingly may have effects on specific brain regions receiving input from somatic afferent stimulation to affect BP. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Cardiovascular Blood Pressure | Mechanism |
| 29853959 | Therefore, we hypothesised that acupuncture at LR3 would alter cerebral glucose metabolism as measured by PET-CT in a manner associated with lowered BP. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Blood Pressure | Mechanism |
| 29853959 | BP Measurement | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Blood Pressure | Mechanism |
| 29853959 | The Kent Scientific CODA noninvasive BP measurement system was used to screen rats. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Blood Pressure | Mechanism |
| 29853959 | Each measurement had 15 cycles and the average BP value was used. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Blood Pressure | Mechanism |
| 29853959 | BP was measured between 9:30 am and 2:30 pm when it was stable. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Blood Pressure | Mechanism |
| 29853959 | A one-way analysis of variance was used to evaluate between-group differences in BP. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Blood Pressure | Mechanism |
| 29853959 | Therefore, we speculate that acupuncture may reduce BP by inhibiting oxidative stress response, which is regulated by ROS formation and PPP. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Stress Response Blood Pressure | Mechanism |
| 29853959 | Our current research focuses on the effect of acupuncture on BP and the identification of changes of glucose metabolism of target brain regions in SHRs, and the results showed that there was no antihypertensive effect at 72 hours after 7-day acupuncture. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Blood Pressure | Mechanism |
| 29853959 | Indeed, there are many other valuable acupoints to reduce BP, such as KI3, ST36, or acupoint compatibility, which is also one of our future research directions. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Blood Pressure | Mechanism |
| 25206591 | control group; bP < 0.05, vs. | Neural Regen Res. 2013 Jan 25;8(3):218-25. doi: 10.3969/j.issn.1673-5374.2013.03.003. | Blood Pressure | Mechanism |
| 25206591 | control group; bP < 0.05, vs. | Neural Regen Res. 2013 Jan 25;8(3):218-25. doi: 10.3969/j.issn.1673-5374.2013.03.003. | Blood Pressure | Mechanism |
| 25206591 | control group; bP < 0.05, vs. | Neural Regen Res. 2013 Jan 25;8(3):218-25. doi: 10.3969/j.issn.1673-5374.2013.03.003. | Blood Pressure | Mechanism |
| 25206591 | control group; bP < 0.05, vs. | Neural Regen Res. 2013 Jan 25;8(3):218-25. doi: 10.3969/j.issn.1673-5374.2013.03.003. | Blood Pressure | Mechanism |
| 25206545 | control group; bP < 0.01, vs. | Neural Regen Res. 2013 Sep 5;8(25):2350-9. doi: 10.3969/j.issn.1673-5374.2013.25.006. | Blood Pressure | Mechanism |
| 25206545 | aP < 0.05, bP < 0.01, vs. | Neural Regen Res. 2013 Sep 5;8(25):2350-9. doi: 10.3969/j.issn.1673-5374.2013.25.006. | Blood Pressure | Mechanism |
| 25206545 | control group; bP < 0.05, cP < 0.01, vs. | Neural Regen Res. 2013 Sep 5;8(25):2350-9. doi: 10.3969/j.issn.1673-5374.2013.25.006. | Blood Pressure | Mechanism |
| 37096024 | Fourthly, libraries were selected for cDNA target fragments of 300 bp and Phusion DNA polymerase was used for 15 PCR cycles. | Neuropsychiatr Dis Treat. 2023 Apr 18;19:951-972. doi: 10.2147/NDT.S398321. eCollection 2023. | Blood Pressure | Mechanism |
| 25206515 | control group; bP < 0.05, vs. | Neural Regen Res. 2013 Aug 5;8(22):2069-77. doi: 10.3969/j.issn.1673-5374.2013.22.006. | Blood Pressure | Mechanism |
| 25206515 | control group; bP < 0.01, vs. | Neural Regen Res. 2013 Aug 5;8(22):2069-77. doi: 10.3969/j.issn.1673-5374.2013.22.006. | Blood Pressure | Mechanism |
| 25206515 | control group; bP < 0.01, vs. | Neural Regen Res. 2013 Aug 5;8(22):2069-77. doi: 10.3969/j.issn.1673-5374.2013.22.006. | Blood Pressure | Mechanism |
| 25206515 | One end was connected to a 10 mL syringe and the other end was connected to a blood pressure monitor (model XJ11D; Shanghai Medical Instruments Co., Ltd., Shanghai, China). | Neural Regen Res. 2013 Aug 5;8(22):2069-77. doi: 10.3969/j.issn.1673-5374.2013.22.006. | Blood Pressure | Mechanism |
| 25206727 | normal group (NC); bP < 0.05, vs. | Neural Regen Res. 2013 Mar 25;8(9):802-8. doi: 10.3969/j.issn.1673-5374.2013.09.004. | Blood Pressure | Mechanism |
| 25206727 | NC; bP < 0.05, vs. | Neural Regen Res. 2013 Mar 25;8(9):802-8. doi: 10.3969/j.issn.1673-5374.2013.09.004. | Blood Pressure | Mechanism |
| 25206727 | NC; bP < 0.05, vs. | Neural Regen Res. 2013 Mar 25;8(9):802-8. doi: 10.3969/j.issn.1673-5374.2013.09.004. | Blood Pressure | Mechanism |
| 25206727 | One end was connected to a 10-mL syringe and the other end was connected to a blood pressure monitor (Shanghai Medical Instruments Co., Ltd., Shanghai, China). | Neural Regen Res. 2013 Mar 25;8(9):802-8. doi: 10.3969/j.issn.1673-5374.2013.09.004. | Blood Pressure | Mechanism |
| 37383281 | aP < 0.05, compared to the Con group; bP < 0.05, compared to the Model group. | World J Psychiatry. 2023 Jun 19;13(6):340-350. doi: 10.5498/wjp.v13.i6.340. eCollection 2023 Jun 19. | Blood Pressure | Mechanism |
| 37383281 | aP < 0.05, compared to the Con group; bP < 0.05, compared to the Model group. | World J Psychiatry. 2023 Jun 19;13(6):340-350. doi: 10.5498/wjp.v13.i6.340. eCollection 2023 Jun 19. | Blood Pressure | Mechanism |
| 37383281 | aP < 0.05, compared to the Con group; bP < 0.05, compared to the Model group. | World J Psychiatry. 2023 Jun 19;13(6):340-350. doi: 10.5498/wjp.v13.i6.340. eCollection 2023 Jun 19. | Blood Pressure | Mechanism |
| 37383281 | aP < 0.05, compared to the Con group; bP < 0.05, compared to the Model group. | World J Psychiatry. 2023 Jun 19;13(6):340-350. doi: 10.5498/wjp.v13.i6.340. eCollection 2023 Jun 19. | Blood Pressure | Mechanism |
| 37383281 | aP < 0.05, compared to the Con group; bP < 0.05, compared to the Model group. | World J Psychiatry. 2023 Jun 19;13(6):340-350. doi: 10.5498/wjp.v13.i6.340. eCollection 2023 Jun 19. | Blood Pressure | Mechanism |
| 25767501 | sham group; bP < 0.05, vs. | Neural Regen Res. 2012 Jan 25;7(3):207-11. doi: 10.3969/j.issn.1673-5374.2012.03.009. | Blood Pressure | Mechanism |
| 25767501 | sham group; bP < 0.05, vs. | Neural Regen Res. 2012 Jan 25;7(3):207-11. doi: 10.3969/j.issn.1673-5374.2012.03.009. | Blood Pressure | Mechanism |
| 26889195 | RNA yield was approximately 2 µg/mg, and ~740-bp DNA fragments were obtained, consistent with the expected β-actin band (Figure 3B). | Neural Regen Res. 2015 Dec;10(12):2033-9. doi: 10.4103/1673-5374.172323. | Blood Pressure | Mechanism |
| 25767502 | normal control group; bP < 0.05, vs. | Neural Regen Res. 2012 Jan 25;7(3):212-8. doi: 10.3969/j.issn.1673-5374.2012.03.010. | Blood Pressure | Mechanism |
| 25767502 | normal control group; bP < 0.05, vs. | Neural Regen Res. 2012 Jan 25;7(3):212-8. doi: 10.3969/j.issn.1673-5374.2012.03.010. | Blood Pressure | Mechanism |
| 25767502 | the normal control group; bP < 0.05, vs. | Neural Regen Res. 2012 Jan 25;7(3):212-8. doi: 10.3969/j.issn.1673-5374.2012.03.010. | Blood Pressure | Mechanism |
| 25767502 | normal control group; bP < 0.05, vs. | Neural Regen Res. 2012 Jan 25;7(3):212-8. doi: 10.3969/j.issn.1673-5374.2012.03.010. | Blood Pressure | Mechanism |
| 30431067 | aP<0.05, significantly different from the sham-operated (sham) group; bP<0.05, significantly different from the MCAO group; cP<0.05, significantly different from the MCAO + Acupuncture group. | Int J Mol Med. 2019 Jan;43(1):221-232. doi: 10.3892/ijmm.2018.3981. Epub 2018 Nov 6. | Blood Pressure | Mechanism |
| 30431067 | aP<0.05, significantly different from the sham-operated (sham) group; bP<0.05, significantly different from the MCAO group. | Int J Mol Med. 2019 Jan;43(1):221-232. doi: 10.3892/ijmm.2018.3981. Epub 2018 Nov 6. | Blood Pressure | Mechanism |
| 30431067 | aP<0.05, significantly different from the sham-operated (sham) group; bP<0.05, significantly different from the MCAO group. | Int J Mol Med. 2019 Jan;43(1):221-232. doi: 10.3892/ijmm.2018.3981. Epub 2018 Nov 6. | Blood Pressure | Mechanism |
| 30431067 | aP<0.05, significantly different from the sham-operated (sham) group; bP<0.05, significantly different from the MCAO group; cP<0.05, significantly different from the MCAO + Acupuncture group. | Int J Mol Med. 2019 Jan;43(1):221-232. doi: 10.3892/ijmm.2018.3981. Epub 2018 Nov 6. | Blood Pressure | Mechanism |
| 30431067 | aP<0.05, significantly different from the sham-operated (sham) group; bP<0.05, significantly different from the MCAO group; cP<0.05, significantly different from the MCAO + Acupuncture group. | Int J Mol Med. 2019 Jan;43(1):221-232. doi: 10.3892/ijmm.2018.3981. Epub 2018 Nov 6. | Blood Pressure | Mechanism |
| 30431067 | aP<0.05, significantly different from the sham-operated (sham) group; bP<0.05, significantly different from the MCAO group; cP<0.05, significantly different from the MCAO + Acupuncture group. | Int J Mol Med. 2019 Jan;43(1):221-232. doi: 10.3892/ijmm.2018.3981. Epub 2018 Nov 6. | Blood Pressure | Mechanism |
| 30431067 | aP<0.05, significantly different from the sham-operated (sham) group; bP<0.05, significantly different from the MCAO group; cP<0.05, significantly different from the MCAO + Acupuncture group. | Int J Mol Med. 2019 Jan;43(1):221-232. doi: 10.3892/ijmm.2018.3981. Epub 2018 Nov 6. | Blood Pressure | Mechanism |
| 30431067 | aP<0.05, significantly different from the sham-operated (sham) group; bP<0.05, significantly different from the MCAO group; cP<0.05, significantly different from the MCAO + Acupuncture group. | Int J Mol Med. 2019 Jan;43(1):221-232. doi: 10.3892/ijmm.2018.3981. Epub 2018 Nov 6. | Blood Pressure | Mechanism |
| 31322212 | After 21 days, their kidney function, blood pressure and urinary protein levels were measured. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Blood Pressure Kidney | Mechanism |
| 23997794 | The blood perfusion (BP) on the calf around bladder meridian area was measured with a laser Doppler perfusion imager before, during, and after acupuncture. | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | The whole scanning field was divided into seven subareas, and mean BP on each area was calculated. | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | The ratio of mean BP between a subarea and a reference subarea was gotten, and then the change rate was calculated as ratio change rate (RCR). | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | Acupuncture effect was represented partly by blood perfusion (BP) or blood flow (BF) in several experiments. | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure Blood Flow | Mechanism |
| 23997794 | The imaging technique which can measure BP level on skin has been used in evaluating the efficiency of acupuncture. | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | It has great advantages of being objective and having ability of measuring BP level on different parts of body surface. | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | The BP on the skin of calf around bladder meridian area was measured by a PeriScan PIM II laser Doppler perfusion imager (made in Sweden). | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | Measuring of BP before acupuncture was given for one time and then the acupuncture was started. | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | During the needle retention period, the BP was continuously measured for five times, which took totally about 20 minutes. | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | After withdrawal of the needle, the BP was measured again for three times, which took about 10 minutes. | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | Calculation of Mean BP and Statistics | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | After the seven subareas were divided, mean BP level in each area was calculated automatically by LDPIwin2.5 software which was obtained with the instrument. | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | An important data analysis was achieved in our previous study that the BP at a reference area was gotten to represent the whole body change which was influenced by various unknown factors and by nonspecific effect of acupuncture. | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | To enlarge the specific effects and minimize the fluctuation and nonspecific whole body effect of acupuncture, the ratio (BPi/BPrf) between the BP on one area (BPi) except the reference area (area 7) and the BP on reference area (BPrf) was calculated as RBPi (i is 1 to 6), and then the change rate of the ratio by time was calculated as (RBPt â RBPb)/RBPb, (b denotes before acupuncture) again on each area (area 1 to area 6) which was called ratio change rate (RCR) in percentage (t is 2 to 9, representing nine measured times). | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | After the ratio between the BP on one area and the BP on reference area (RBPi) was calculated and ratio change rate (RCRt) at different times was calculated, the mean RCRs of 20 subjects at six subareas are shown in Table 1. | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | The difference in the RCR of BP on control area (area 4) that is similar to the size of meridian area (area 3) was not significant between on meridian group and off meridian group during most periods. | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | measured the blood perfusion at deep tissue using a needle-type detector and found little difference in increase of BP during acupuncture. | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | This result was similar to our observation that the difference in BP level on area 1 Chengshan (BL 57) which is a point-like small area was not significant between needling the two nonacupoints. | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | Ratio change rate (RCR) of BP on bladder meridian (area 3) when needling at nonacupoint on bladder meridian (blue line) and at nonacupoint off bladder meridian (red line). | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | The local effect of ratio change rate (RCR) of BP around the needling points. | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 23997794 | Ratio change rates of BP in on meridian group (blue line) and off meridian group (red line). | Evid Based Complement Alternat Med. 2013;2013:426052. doi: 10.1155/2013/426052. Epub 2013 Aug 12. | Blood Pressure | Mechanism |
| 33229729 | A fragment of ~328 bp in the GSK-3β promoter region was amplified. | Neural Regen Res. 2021 May;16(5):916-923. doi: 10.4103/1673-5374.297090. | Blood Pressure | Mechanism |
| 25657670 | normal control group; bP < 0.05, vs. | Neural Regen Res. 2012 Jun 25;7(18):1378-85. doi: 10.3969/j.issn.1673-5374.2012.18.003. | Blood Pressure | Mechanism |
| 25657670 | normal control group; bP < 0.05, vs. | Neural Regen Res. 2012 Jun 25;7(18):1378-85. doi: 10.3969/j.issn.1673-5374.2012.18.003. | Blood Pressure | Mechanism |
| 25657670 | normal control group; bP < 0.05, vs. | Neural Regen Res. 2012 Jun 25;7(18):1378-85. doi: 10.3969/j.issn.1673-5374.2012.18.003. | Blood Pressure | Mechanism |
| 25657670 | normal control group; bP < 0.05, vs. | Neural Regen Res. 2012 Jun 25;7(18):1378-85. doi: 10.3969/j.issn.1673-5374.2012.18.003. | Blood Pressure | Mechanism |
| 26998388 | Trials indicate hypoglycemic, cardiovascular, antiviral, psychomotor enhancement, blood pressure normalization and asthma control properties. | J Pharmacopuncture. 2015 Dec;18(4):38-44. doi: 10.3831/KPI.2015.18.036. | Cardiovascular Blood Pressure | Mechanism |
| 33505601 | If the mouse could not find the platform within 90 s, the escape latency was recorded as 90 s. aP < 0.05 when compared to senescence-accelerated mouse resistant 1 control group, bP < 0.05 when compared to senescence-accelerated mouse prone 8 (SAMP8) control group, cP < 0.05 when compared to SAMP8 sham operation group, dP < 0.05 when compared to SAMP8 neural stem cells transplantation with non-acupoint group. | World J Stem Cells. 2020 Dec 26;12(12):1576-1590. doi: 10.4252/wjsc.v12.i12.1576. | Blood Pressure | Mechanism |
| 33505601 | aP < 0.05 when compared to senescence-accelerated mouse prone 8 (SAMP8) neural stem cells (NSCs) transplantation group, bP < 0.05 when compared to SAMP8 NSCs transplantation with non-acupoint group. | World J Stem Cells. 2020 Dec 26;12(12):1576-1590. doi: 10.4252/wjsc.v12.i12.1576. | Blood Pressure | Mechanism |
| 33505601 | aP < 0.05 when compared to senescence-accelerated mouse resistant 1 control group, bP < 0.05 when compared to senescence-accelerated mouse prone 8 (SAMP8) control group, cP < 0.05 when compared to SAMP8 sham operation group, dP < 0.05 when compared to SAMP8 neural stem cells transplantation with non-acupoint group. | World J Stem Cells. 2020 Dec 26;12(12):1576-1590. doi: 10.4252/wjsc.v12.i12.1576. | Blood Pressure | Mechanism |
| 18955337 | 2); peripheral oxygen saturation at the tail stump; blood pressure in the left femoral artery (Cardiocap, Datex, Hoevelaken, Netherlands) and regional cerebral oxygen saturation (INVOS 5100, Somanetics, Troy, MI, USA). | Evid Based Complement Alternat Med. 2010 Jun;7(2):151-5. doi: 10.1093/ecam/nen034. Epub 2008 Nov 5. | Blood Pressure | Mechanism |
| 27073385 | A distinguishing aspect of acupuncture is its ability to trigger significant modulation in different areas of the brain, in addition to changes in blood pressure and cardiovascular excitatory reflex responses (Li et al., 2010, 2012). | Neural Regen Res. 2016 Feb;11(2):305-11. doi: 10.4103/1673-5374.177740. | Cardiovascular Blood Pressure | Mechanism |
| 32547407 | Some clinical symptoms of PCOS such as hyperandrogen, high blood pressure, and anxiety are highly related to the sympathetic nerve system or imbalance of sympathetic and the parasympathetic nerve. | Front Physiol. 2020 May 29;11:474. doi: 10.3389/fphys.2020.00474. eCollection 2020. | Anxiety Blood Pressure | Mechanism |
| 37384285 | Several studies have demonstrated that the stimulation of Nei-guan (PC-6), an acupoint over the wrist, is most effective in lowering blood pressure and improving cardiovascular diseases. | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Cardiovascular Blood Pressure | Mechanism |
| 37384285 | Our clinical trials showed that PC-6 electrical stimulation induces a decrease in blood pressure through the activation of the C-fibers of the median nerve. | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Blood Pressure | Mechanism |
| 37384285 | Measurement of blood pressure and immobilization stress-induced hypertension (IMH) | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Blood Pressure | Mechanism |
| 37384285 | Effect of warm needle acupuncture at PC-6 on systolic blood pressure in an IMH rat model | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Blood Pressure | Mechanism |
| 37384285 | To explore the effect of WAI stimulation at two different temperatures, 42 or 52°C, on hypertension, systolic blood pressure following WAI stimulation was measured in the tail of rats with IMH by using a noninvasive blood pressure monitoring system (Figures 2A,B). | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Blood Pressure | Mechanism |
| 37384285 | Effect of warm needle acupuncture at PC-6 on systolic blood pressure (BP) in immobilization stress-induced hypertension (IMH) rats. | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Blood Pressure | Mechanism |
| 37384285 | (A) Schematic showing the experimental procedure for the measurement of systolic BP in the rat model of IMH. | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Blood Pressure | Mechanism |
| 37384285 | (B) A representative example of the measurement of BP in a computer-controlled system. | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Blood Pressure | Mechanism |
| 37384285 | Effect of TRPV1 activation at PC-6 on systolic blood pressure in rats with immobilization stress-induced hypertension (IMH). | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Blood Pressure | Mechanism |
| 37384285 | Our previous study also revealed that PC-6 stimulation by a TRPV1 agonist capsaicin patch reduced blood pressure in hypertensive participants. | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Blood Pressure | Mechanism |
| 37384285 | Additionally, while a previous study reported that somatic pain-associated TRPV1 activation can produce sympathetic reflexes leading to an increase of blood pressure, the present study showed that focal activation of TRPV1 receptors at PC6 generated anti-hypertensive effects. | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Blood Pressure | Mechanism |
| 37384285 | Our previous study also showed that chemical stimulation of TRPV1 at PC6 over the median nerve reduced the systolic BP. | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Blood Pressure | Mechanism |
| 37384285 | The reductions in systolic BP are more profound after localized stimulation of the median nerve than after stimulation of the ulnar nerve site. | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Blood Pressure | Mechanism |
| 37384285 | It may suggest that the specific mediation of median nerve in the nerve stimulation-induced reduction of elevated BP and a critical contribution of TRPV1 receptors over median nerve to PC6-mediated BP reduction. | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Blood Pressure | Mechanism |
| 37384285 | Our previous study found that blocking A-fibers in hypertensive participants did not prevent the TENS-induced blood pressure-lowering effect, but stimulating C-fibers by capsaicin at the PC-6 acupoint produced acupuncture-like effects on hypertension. | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Blood Pressure | Mechanism |
| 34804173 | S-con group, bP < 0.05 vs. | Evid Based Complement Alternat Med. 2021 Nov 12;2021:1418616. doi: 10.1155/2021/1418616. eCollection 2021. | Blood Pressure | Mechanism |
| 34804173 | S-con group, bP < 0.05 vs. | Evid Based Complement Alternat Med. 2021 Nov 12;2021:1418616. doi: 10.1155/2021/1418616. eCollection 2021. | Blood Pressure | Mechanism |
| 34804173 | S-con group, bP < 0.05 vs. | Evid Based Complement Alternat Med. 2021 Nov 12;2021:1418616. doi: 10.1155/2021/1418616. eCollection 2021. | Blood Pressure | Mechanism |
| 34804173 | control group, bP < 0.05 vs. | Evid Based Complement Alternat Med. 2021 Nov 12;2021:1418616. doi: 10.1155/2021/1418616. eCollection 2021. | Blood Pressure | Mechanism |
| 34804173 | S-con group, bP < 0.05 vs. | Evid Based Complement Alternat Med. 2021 Nov 12;2021:1418616. doi: 10.1155/2021/1418616. eCollection 2021. | Blood Pressure | Mechanism |
| 34804173 | S-con group, bP < 0.05 vs. | Evid Based Complement Alternat Med. 2021 Nov 12;2021:1418616. doi: 10.1155/2021/1418616. eCollection 2021. | Blood Pressure | Mechanism |
| 34804173 | S-con group, bP < 0.05 vs. | Evid Based Complement Alternat Med. 2021 Nov 12;2021:1418616. doi: 10.1155/2021/1418616. eCollection 2021. | Blood Pressure | Mechanism |
| 32039692 | We developed a combined mechano-electrical acupuncture device (MEA) and examined the effects of acupuncture at Neuro-Sps on systolic blood pressure (BP) in a rat model of immobilization-induced hypertension (IMH) and the mediation of endogenous opioid systems in its effect. | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Blood Pressure | Mechanism |
| 32039692 | Immobilization-induced hypertension and measurement of blood pressure | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Blood Pressure | Mechanism |
| 32039692 | Systolic blood pressure (BP) was measured non-invasively with a tail cuff blood pressure monitor (Model 47, IITC Inc., CA, USA). | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Blood Pressure | Mechanism |
| 32039692 | The mean of two readings was taken at each BP measurement. | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Blood Pressure | Mechanism |
| 32039692 | After measurement of blood pressure, the brains were taken out, fixed in paraformaldehyde (PFA), cryo-protected, cryo-sectioned 30 μm thick and incubated in blocking solutions containing 0.3% Triton X-100, 5% normal goat serum in 0.1 M PBS at room temperature for 1 h. The sections were incubated with primary antibody for c-Fos (1:200) overnight at 4 °C, followed by an incubation of secondary antibody with donkey anti-rabbit Alexa Fluor 594. | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Blood Pressure | Mechanism |
| 32039692 | Effects of stimulation of neurogenic spots on systolic blood pressure in a rat model of immobilization-induced hypertension | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Blood Pressure | Mechanism |
| 32039692 | Effects of electrical and/or mechanical acupuncture at neurogenic spots on systolic blood pressure in IMH rats. | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Blood Pressure | Mechanism |
| 32039692 | BP blood pressure, EBD Evans blue dye | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Blood Pressure | Mechanism |
| 32039692 | Next, we tested the effect of electrical and/or mechanical stimulation of needles inserted into Neuro-Sps on the development of systemic blood pressure (BP) in IMH rats. | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Blood Pressure | Mechanism |
| 32039692 | Immobilization stress in rats gradually increased systolic BP, reaching approximately 160 mmHg over the next 2 h (Con; Fig. 2c), consistent with our previous study. | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Blood Pressure | Mechanism |
| 32039692 | Role of endogenous opioids in rVLM in the inhibitory effects of neurogenic spot stimulation on elevated blood pressure | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Blood Pressure | Mechanism |
| 32039692 | Although naloxone group slightly decrease blood pressure up to 40Â min after naloxone administration, there are no differences in the blood pressure during the time points between naloxone and saline groups. | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Blood Pressure | Mechanism |
| 32039692 | It suggests that the effects of acupuncture at Neuro-Sps on systolic BP are mediated via the endogenous opioid system of the rVLM in IMH rats. | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Blood Pressure | Mechanism |
| 32039692 | In our previous studies, when Neuro-Sps are stimulated electrically or manually, the increase in BP in the IMH rat or colonic inflammation in colitis rats is alleviated. | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Blood Pressure | Mechanism |
| 32039692 | Furthermore, an experimental median nerve A-fiber block established prior to electrical stimuli at PC6 failed to prevent the BP-lowering effects of TENS. | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Blood Pressure | Mechanism |
| 32039692 | The present study revealed that stimulation of Neuro-Sps near the wrist activated vlPAG and rVLM and injection of naloxone into rVLM reversed acupuncture effects on elevated BP. | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Blood Pressure | Mechanism |
| 29849693 | Hyperglycemia control, blood pressure control, and the use of angiotensin converting enzyme inhibitors or angiotensin receptor antagonists are standard treatment for patients with DN. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Blood Pressure | Mechanism |
| 27880769 | After 4 weeks of treatment, compared with Sham group, aP<0.05; Compared with SNCr group, bP<0.05; Compared with treadmill group, cP<0.05. | PLoS One. 2016 Nov 23;11(11):e0164652. doi: 10.1371/journal.pone.0164652. eCollection 2016. | Blood Pressure | Mechanism |
| 25887143 | Catheters were inserted into the left carotid artery and the jugular vein for blood pressure monitoring and drug injection, respectively. | BMC Complement Altern Med. 2015 Mar 27;15:87. doi: 10.1186/s12906-015-0625-4. | Blood Pressure | Mechanism |
| 25887143 | Heart rate and blood pressure were continuously monitored and body temperature was maintained around 37°C by means of a feedback- controlled homeothermic blanket. | BMC Complement Altern Med. 2015 Mar 27;15:87. doi: 10.1186/s12906-015-0625-4. | Heart Rate Blood Pressure | Mechanism |
| 25624811 | Pre-ischemia electro-acupuncture stimulation is particularly important for specific high-risk groups, such as patients with high blood pressure or other congenital characteristics that predispose them to stroke. | Neural Regen Res. 2012 Aug 25;7(24):1859-65. doi: 10.3969/j.issn.1673-5374.2012.24.003. | Blood Pressure | Mechanism |
| 31275411 | If the average quality value within the window falls lower than 20, truncate the back base from the window and then remove the sequence shorter than 50 bp during the quality control; (2) match barcodes exactly, allow mismatches up to 2 bases for primers, and remove ambiguous bases; (3) stitch the sequences of the two ends according to the overlapping base overlap, with the overlap being greater than 10bp. | Evid Based Complement Alternat Med. 2019 Jun 2;2019:4958294. doi: 10.1155/2019/4958294. eCollection 2019. | Blood Pressure | Mechanism |
| 31275411 | In total of 941,816 high-quality 16S rRNA sequences were generated from 21 fecal samples (length distribution in 420-460 bp) and the average length of the sequence was 439 per each sample obtained (min: 328, max: 461). | Evid Based Complement Alternat Med. 2019 Jun 2;2019:4958294. doi: 10.1155/2019/4958294. eCollection 2019. | Blood Pressure | Mechanism |
| 36116306 | There was no difference in blood pressure, pulse rate, hematological indexes and biochemical indexes of patients before and after using the treatment regimen. | Int J Surg Case Rep. 2022 Oct;99:107600. doi: 10.1016/j.ijscr.2022.107600. Epub 2022 Sep 7. | Heart Rate Blood Pressure | Mechanism |