- The advantages of acupuncture anesthesia in clinical practice
In clinical practice, acupuncture anesthesia presents a multitude of advantages, pivotal among these being Body System Protection. This technique supports the body's natural defenses, reducing the physiological stress often associated with surgical procedures. By modulating the body's response to pain, acupuncture anesthesia allows for a lower Dosage of Medication, significantly reducing the potential for drug-related side effects. Furthermore, this approach plays a crucial role in Emotion Regulation, helping patients maintain a calm and stable emotional state, which is essential for a positive surgical outcome. The impact of acupuncture on the nervous system not only aids in Pain Relief but also promotes Enhanced Recovery After Surgery. Patients tend to experience faster recuperation times, attributed to the holistic nature of this method. Additionally, acupuncture anesthesia is associated with a Lower Incidence of Side Effects compared to conventional anesthetics. Its ability to modulate and balance the body's responses makes it an invaluable tool in the realm of modern medicine, offering a safer, more patient-centered approach to pain management and recovery.
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Body System Protection
- Brain Protection
- Acupuncture anesthesia plays a vital role in brain surgeries, ensuring precise and safe anesthesia, reducing the risk of neurological complications, and supporting optimal cognitive function.
- Lung Protection
- Acupuncture anesthesia reduces post-operative lung complications, aiding in rapid lung function recovery, particularly beneficial for lung surgeries.
- Neuroprotection
- Acupuncture anesthesia is crucial for safeguarding the nervous system, reducing nerve injuries, and preventing the progression of neurological disorders.
- Kidney
- Acupuncture anesthesia alleviates stress on the kidneys, reducing the risk of kidney injury, particularly valuable in kidney surgeries.
- Gastrointestinal Tract
- Acupuncture anesthesia supports gastrointestinal health, reducing the risk of post-operative digestive issues, and ensuring a smoother recovery.
- Cardiovascular
- Acupuncture anesthesia eases the cardiovascular system's burden, reducing the risk of cardiovascular complications, especially in cardiac surgeries.
- Myocardium
- Acupuncture anesthesia aids in protecting the myocardium, minimizing adverse effects on heart muscle, ensuring cardiac health.
- Cognitive Function
- Through emotional stability and neuroprotection, acupuncture anesthesia helps preserve cognitive function, reducing the risk of post-operative cognitive impairment.
- Motor Function
- Acupuncture anesthesia improves motor function, aiding in post-operative mobility, and enhancing overall quality of life.
- Language Function
- Acupuncture anesthesia supports language function rehabilitation, assisting patients in regaining their communication skills.
- Learning and Memory Ability
- Acupuncture anesthesia, by reducing post-operative pain and emotional instability, enhances learning and memory ability, promoting a speedy recovery.
Acupuncture anesthesia for Body System Protection-Cardiovascular
| PMID | Evidence | Source | Keyword | Type |
|---|---|---|---|---|
| 10579242 | By affecting the appropriate acupuncture points by the generation of high frequency microwaves (52-78 GHz), remarkable clinical results are being achieved in surgery, orthopedic and traumatology, cardiovascular disorders, urology, gynecology, dermatology, gastroenterology, pulmology, upper respiratory tract, cardiology, neurology, and oncology during the last decade--the MRT being contraindicated only in the cases of acute pain in the abdomen demanding an operation, pregnancy, and menstruation cycle. | Acupunct Electrother Res. 1999;24(2):105-25. doi: 10.3727/036012999816356390. | Cardiovascular | Review |
| 24684116 | Authors of the present paper review recent progress of researches on acupuncture therapy in resisting MI from 1) improving cardiovascular function and promoting angiogenesis, and 2) protecting myocardial cells from further injury and reducing cellular apoptosis at different pathological stages of MI. | Zhen Ci Yan Jiu. 2014 Feb;39(1):73-8. | Cardiovascular | Review |
| 1581649 | Acupuncture for cardiovascular disorders. | Probl Vet Med. 1992 Mar;4(1):125-31. | Cardiovascular | Review |
| 1581649 | Experimental studies in animals and clinical studies in humans have demonstrated that acupuncture can exert significant effects on the cardiovascular system and provide effective therapy for a variety of cardiovascular ailments. | Probl Vet Med. 1992 Mar;4(1):125-31. | Cardiovascular | Review |
| 18630550 | This paper reviewed advances of the studies on the mechanisms of acupuncture treatment, and acupuncture treating pain, nausea and vomiting, neurodegenerative diseases, cerebrovascular and cardiovascular diseases and so on in recent years abroad. | Zhongguo Zhen Jiu. 2008 Jun;28(6):463-7. | Cardiovascular Nausea and Vomiting | Review |
| 18992625 | Acupuncture has been used for thousands of years in Eastern medicine to treat multiple medical conditions and has been documented to improve many aspects of cardiovascular functioning. | Heart Lung. 2008 Nov-Dec;37(6):425-31. doi: 10.1016/j.hrtlng.2007.11.002. Epub 2008 Sep 11. | Cardiovascular | Review |
| 19127488 | This review highlights the pharmacological mechanisms underlying the neurological (sensory), cardiovascular and gastrointestinal effects of electroacupuncture. | Curr Opin Investig Drugs. 2009 Jan;10(1):62-9. | Cardiovascular | Review |
| 20209980 | Clinical studies have shown that acupuncture therapy is effective for certain cardiovascular diseases, especially cardiac arrhythmia resulting from neural dysfunction. | Zhen Ci Yan Jiu. 2009 Dec;34(6):413-20. | Cardiovascular | Review |
| 20209980 | Therefore, the acupuncture effects on cardiovascular disorders are dependent on an integrated mechanism mediated by multiple factors at central and peripheral levels. | Zhen Ci Yan Jiu. 2009 Dec;34(6):413-20. | Cardiovascular | Review |
| 20626152 | In the present paper, the authors review progresses of researches on the protective effect of acupuncture in resisting acute myocardial ischemia-reperfusion injury in patients and animals from (1) resisting injury of oxygen-derived free radicals, (2) reducing intracellular Ca2+ overload, (3) relieving dysfunction of vascular endothelial cells of the myocardium, (4) regulating immune functional activity and reducing inflammatory injury, (5) reducing cardiocyte apoptosis, (6) upregulating the expression of heat shock protein (HSP 70) in the myocardium, and (7) regulating activities of multiple cardiovascular protection factors and intracellular signaling pathways. | Zhen Ci Yan Jiu. 2010 Apr;35(2):156-60. | Immunity Cardiovascular Myocardium | Review |
| 20626152 | For this reason, the authors hold that the coming researches on acupuncture therapy for cardiovascular disorders should pay more attention to its clinical application, for example, controlled blood-pressure decline induced lower perfusion of the coronary artery, cardiac surgery (percutaneous tranluminal coronary angioplasty, intracardiac operation underdirect vision) etc. | Zhen Ci Yan Jiu. 2010 Apr;35(2):156-60. | Cardiovascular Blood Pressure | Review |
| 2205777 | We review evidence that supports the concept that many of the cardiovascular, analgesic, and behavioral effects of exercise are mediated by this mechanism and that the same or similar mechanisms are responsible for the central and peripheral effects of acupuncture. | Med Sci Sports Exerc. 1990 Aug;22(4):417-28. | Cardiovascular | Review |
| 24215923 | Acupuncture has been in practice in China for more than 3000 years and used to treat a wide variety of conditions including cardiovascular and psychiatric diseases, acute, and chronic pain. | Int Rev Neurobiol. 2013;111:181-95. doi: 10.1016/B978-0-12-411545-3.00009-2. | Cardiovascular | Review |
| 24215927 | Although mechanisms underlying acupuncture regulation of pain have been studied by a number of laboratories in many countries, much less is known about its ability to modulate cardiovascular function. | Int Rev Neurobiol. 2013;111:257-71. doi: 10.1016/B978-0-12-411545-3.00013-4. | Cardiovascular | Review |
| 24215927 | First, point-specific effects of acupuncture underlie its cardiovascular actions. | Int Rev Neurobiol. 2013;111:257-71. doi: 10.1016/B978-0-12-411545-3.00013-4. | Cardiovascular | Review |
| 24215927 | Third, repetitive acupuncture through a molecular mechanism can cause prolonged cardiovascular effects that far outlast acupuncture stimulation. | Int Rev Neurobiol. 2013;111:257-71. doi: 10.1016/B978-0-12-411545-3.00013-4. | Cardiovascular | Review |
| 24215927 | Fourth, there is a range of cardiovascular responsiveness to acupuncture that depends, at least in part, on interactions between neural modulators that synaptically regulate autonomic function in the brain stem. | Int Rev Neurobiol. 2013;111:257-71. doi: 10.1016/B978-0-12-411545-3.00013-4. | Cardiovascular | Review |
| 24215927 | Thus, acupuncture has the capability of profoundly regulating cardiovascular function in patients with disease, for example, hypertension, and the experimental laboratory is directing best approaches to study its actions in humans. | Int Rev Neurobiol. 2013;111:257-71. doi: 10.1016/B978-0-12-411545-3.00013-4. | Cardiovascular | Review |
| 24684116 | Authors of the present paper review recent progress of researches on acupuncture therapy in resisting MI from 1) improving cardiovascular function and promoting angiogenesis, and 2) protecting myocardial cells from further injury and reducing cellular apoptosis at different pathological stages of MI. | Zhen Ci Yan Jiu. 2014 Feb;39(1):73-8. | Cardiovascular | Review |
| 24684118 | Acupuncture therapy has been confirmed to be effective in treating cardiovascular diseases in clinical practice. | Zhen Ci Yan Jiu. 2014 Feb;39(1):83-6. | Cardiovascular | Review |
| 24684118 | In the present paper, the authors review progress of studies on acupuncture treatment of cardiovascular diseases from 1) regulating cardiac sympathetic-beta-adrenergic receptor activity and myocardial intracellular GTP-binding protein (Gs)-adenylylcyclase (AC)-cyclic adenosine monophosphate (cAMP)-protein kinase (PKA) signaling, and 2) balancing cardiac sympathetic and vagal nerve activities. | Zhen Ci Yan Jiu. 2014 Feb;39(1):83-6. | Cardiovascular | Review |
| 24684118 | Due to limited experimental conditions, in-depth studies about the mechanisms of acupuncture intervention underlying improvement of cardiovascular functions are relatively fewer up to now. | Zhen Ci Yan Jiu. 2014 Feb;39(1):83-6. | Cardiovascular | Review |
| 24929454 | Acupuncture may trigger a somatic autonomic reflex, thereby affecting the gastric and cardiovascular functions. | J Acupunct Meridian Stud. 2014 Jun;7(3):105-14. doi: 10.1016/j.jams.2013.07.008. Epub 2013 Aug 17. | Cardiovascular | Review |
| 25543450 | Literature regarding the basic research of acupuncture-moxibustion serum for last more than 10 years is reviewed, and the effects of acupuncture-moxibustion serum on respiratory system, digestive system, cardiovascular system, nervous system, immune system, anti-aging, bone metabolism and anti-cancer are summarized, hoping to provide references for clinical treatment and evidence-based medicine. | Zhongguo Zhen Jiu. 2014 Oct;34(10):1042-6. | Immunity Gastrointestinal Tract Cardiovascular | Review |
| 26054160 | The results of Meta-analysis indicate that based on regular western medicine, additional use of acupuncture could further improve symptoms of angina, increase efficacy of electrocardiogram (ECG) and reduce the dosage of nitroglycerin, in the meanwhile the hemorheology could be ameliorated, and the contents of C reactive protein (CRP), malondialdehyde (MDA), lipid peroxide (LPO), endothelin (ET) could be reduced, while the contents of superoxide dismutase (SOD) and nitric oxide (NO) could be increased; besides, the occurrence rate of cardiovascular event could be reduced without causing obvious adverse events. | Zhongguo Zhen Jiu. 2015 Apr;35(4):407-11. | Cardiovascular | Review |
| 26237841 | Meanwhile, acupuncture has been used for the treatment of cardiovascular diseases, such as hypertension, coronary artery disease, and stroke, but its mechanisms of actions remain poorly understood. | J Tradit Chin Med. 2015 Jun;35(3):343-8. doi: 10.1016/s0254-6272(15)30108-4. | Cardiovascular | Review |
| 27526331 | Finally, some of the evidence in association with mechanisms of action of acupuncture in insomnia, in particular its impact on cardiovascular variables associated with insomnia, is presented, along with findings of systematic reviews. | J Altern Complement Med. 2016 Sep;22(9):684-94. doi: 10.1089/acm.2016.0044. Epub 2016 Aug 15. | Cardiovascular Insomnia | Review |
| 29393105 | We find that, in these hypertensive animals, acupuncture could mainly influence factors related to the nervous system, oxidative stress, the endocrine system, cardiovascular function, and hemorheology, which are closely associated with the stroke outcome. | Complement Med Res. 2018;25(1):45-51. doi: 10.1159/000475930. Epub 2018 Jan 23. | Cardiovascular Endocrinology | Review |
| 29419562 | Acupuncture and Cardiovascular Disease: Focus on Heart Failure. | Cardiol Rev. 2018 Mar/Apr;26(2):93-98. doi: 10.1097/CRD.0000000000000179. | Cardiovascular | Review |
| 29419562 | Acupuncture is a standardized treatment of Traditional Chinese Medicine that has been shown to have beneficial effects on the cardiovascular system via a neurohumoral pathway known as the long-loop pathway. | Cardiol Rev. 2018 Mar/Apr;26(2):93-98. doi: 10.1097/CRD.0000000000000179. | Cardiovascular | Review |
| 30059774 | Acupuncture for the Treatment of Cardiovascular Diseases: A Systematic Review. | J Acupunct Meridian Stud. 2019 Apr;12(2):43-51. doi: 10.1016/j.jams.2018.07.005. Epub 2018 Jul 27. | Cardiovascular | Review |
| 30059774 | Acupuncture, for the westerns countries, is an innovative and low-cost therapy for treatment and prevention of cardiovascular diseases (CVDs). | J Acupunct Meridian Stud. 2019 Apr;12(2):43-51. doi: 10.1016/j.jams.2018.07.005. Epub 2018 Jul 27. | Cardiovascular | Review |
| 30059774 | We conclude that although several studies indicated an improvement in the response of the cardiovascular system in CVDs by acupuncture, electroacupuncture, or electrostimulation treatment, the heterogeneity of the studies does not allow a standardization of its application for each specific disease, making further studies necessary for its use to become a reality. | J Acupunct Meridian Stud. 2019 Apr;12(2):43-51. doi: 10.1016/j.jams.2018.07.005. Epub 2018 Jul 27. | Cardiovascular | Review |
| 32310001 | Acupuncture and related techniques for obesity and cardiovascular risk factors: a systematic review and meta-regression analysis. | Acupunct Med. 2020 Aug;38(4):227-234. doi: 10.1136/acupmed-2018-011646. Epub 2020 Apr 20. | Cardiovascular | Review |
| 32310001 | OBJECTIVE: To assess how acupuncture and related techniques affect weight-related indicators and cardiovascular risk factors compared with non-acupuncture interventions in overweight and obese patients. | Acupunct Med. 2020 Aug;38(4):227-234. doi: 10.1136/acupmed-2018-011646. Epub 2020 Apr 20. | Cardiovascular | Review |
| 33636511 | Roles of central orexinergic system on cardiovascular function and acupuncture on intervention of cardiovascular risk: Orexinergic system mediate the role of acupuncture? | Neuropeptides. 2021 Jun;87:102132. doi: 10.1016/j.npep.2021.102132. Epub 2021 Feb 19. | Cardiovascular | Review |
| 33636511 | We review the improvement of acupuncture on hypertension and psychological stress induced cardiovascular reactivity. | Neuropeptides. 2021 Jun;87:102132. doi: 10.1016/j.npep.2021.102132. Epub 2021 Feb 19. | Cardiovascular | Review |
| 33636511 | We think that acupuncture intervenes hypertension and psychological stress induced cardiovascular reactivity to prevent cardiovascular disease and cardiovascular death. | Neuropeptides. 2021 Jun;87:102132. doi: 10.1016/j.npep.2021.102132. Epub 2021 Feb 19. | Cardiovascular | Review |
| 33636511 | We propose a hypothesis that acupuncture improve hypertension and psychological stress induced cardiovascular reactivity through regulating central orexinergic system. | Neuropeptides. 2021 Jun;87:102132. doi: 10.1016/j.npep.2021.102132. Epub 2021 Feb 19. | Cardiovascular | Review |
| 38081432 | CONCLUSIONS: Research related to acupuncture regulation on the ANS mainly focused on anti-inflammation, and regulating gastrointestinal and cardiovascular function over the past decade. | Complement Ther Med. 2023 Dec 9;80:103009. doi: 10.1016/j.ctim.2023.103009. | Cardiovascular | Review |
| 6303648 | Endogenous opiates controlling cardiovascular and respiratory reflexes are likely to activate mu-receptors, while high-frequency acupuncture may alleviate the symptoms of opiate withdrawal by allowing an increase in Met-enkephalin to activate delta-receptors. | Clin Endocrinol Metab. 1983 Mar;12(1):31-56. doi: 10.1016/s0300-595x(83)80028-0. | Cardiovascular | Review |
| 793374 | Modification of cardiovascular function in dogs by acupuncture: a review. | Am J Chin Med (Gard City N Y). 1976 WINTER;4(4):333-46. doi: 10.1142/s0192415x76000433. | Cardiovascular | Review |
| 793374 | Acupuncture at Jen Chung (Go-26) in dogs under halothane anesthesia produces sympathomimetic-like effects on the cardiovascular system. | Am J Chin Med (Gard City N Y). 1976 WINTER;4(4):333-46. doi: 10.1142/s0192415x76000433. | Cardiovascular | Review |
| 793374 | Acupuncture at Tsu San Li (St-36) results in a parasympathomimetic-like effect on the cardiovascular system which can be inhibited by atropine. | Am J Chin Med (Gard City N Y). 1976 WINTER;4(4):333-46. doi: 10.1142/s0192415x76000433. | Cardiovascular | Review |
| 8791906 | All 177 cardiovascular risk factors are classified into the following 10 major categories, with the 11th category listing those factors now considered to be questionable: 1) Nutrition-Related Cardiovascular Risk Factors (33 risk factors) 2) Internal Cardiovascular Risk Factors Identifiable by Laboratory Tests: Abnormal Blood & Tissue Chemistry Findings Related to Cardiovascular Diseases (35 risk factors) 3) Drug, Chemical, Hormonal, and Nutritional Supplement Intake (Including Drug-Drug Interaction and Drug-Food Interaction) As Cardiovascular Risk Factors (34 risk factors) 4) Signs and Symptoms Associated With a High Incidence of Cardiovascular Diseases (33 risk factors) 5) Non-Invasively Detectable Abnormal Laboratory Findings Associated With Cardiovascular Diseases (13 risk factors) 6) Hereditary Cardiovascular Risk Factors (5 risk factors) 7) Environmental Cardiovascular Risk Factors, Including Air Pollution, Electromagnetic Fields, Materials that Contact the Body Surface, Poisonous Venoms, and Insertion of Needle into Infected Body Tissue by Acupuncture of Injection (14 risk factors) 8) Socioeconomic and Demographic Cardiovascular Risk Factors (7 risk factors) 9) Cardiovascular Risk Factors Related to Medical Care (2 risk factors) 10) Co-existence of Multiple Cardiovascular Risk Factors (1 risk factor) 11) Factors Previously Regarded As Cardiovascular Risk Factors, But Now in Question (7 risk factors) While a few factors, like hereditary characteristics, age, and sex, generally cannot be changed, most of the cardiovascular risk factors can be controlled by changing one's lifestyle, maintaining proper dietary intake, and correcting any existing abnormalities once each individual's unique constellation of cardiovascular risk factors is recognized. | Acupunct Electrother Res. 1996 Jan-Mar;21(1):21-76. doi: 10.3727/036012996816356942. | Cardiovascular | Review |
| 9494036 | For decades, acupuncture and electroneedling treatments have been used, predominately in the Eastern countries, in the management of patients with compromised cardiovascular and digestive functions. | Disabil Rehabil. 1998 Feb;20(2):41-8. doi: 10.3109/09638289809166052. | Gastrointestinal Tract Cardiovascular | Review |
| 22378585 | Experimental studies have shown that the hypothalamic rostral ventrolateral medulla, arcuate nucleus and ventrolateral periaqueductal gray are involved in acupuncture attenuation of sympathoexcitatory cardiovascular reflex responses. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | This long-loop pathway also appears to contribute to the long-lasting, acupuncture-mediated attenuation of sympathetic premotor outflow and excitatory cardiovascular reflex responses. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | Acupuncture of PC6 modulates the activity in the cardiovascular system, an effect that may be attributed to attenuation of sympathoexcitatory cardiovascular reflex responses. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | Modern studies have extensively evaluated the beneficial effect of acupuncture on the cardiovascular system, and it is increasingly clear that acupuncture is effective in treating cardiovascular disorders. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | Acupuncture is used to treat chronic ailments including cardiovascular disease and its symptoms, arrhythmias, palpitations, dyspnoea, vertigo, syncope, hypertension, hypotension and angina. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | The long-loop pathway of the hypothalamic rostral ventrolateral medulla (RVLM), arcuate nucleus (ARC), ventrolateral periaqueductal gray (VLPAG) and medullary raphe are involved in the acupuncture-mediated attenuation of sympathoexcitatory cardiovascular reflex responses. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | It is noteworthy that this long-loop pathway also appears to contribute to the long-lasting, acupuncture-mediated attenuation of sympathetic premotor outflow and excitatory cardiovascular reflex responses. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | The targeting of a well-recognised set of acupoints, located along the pericardial meridian and positioned directly over the median nerve near the wrist by acupuncture stimulation with low current and low frequency in animals decreases the extent of myocardial ischaemia by means of the reduction of myocardial oxygen demand, and it reduces sympathoexcitatory cardiovascular reflex responses, partly through an effect on the RVLM. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | Cardiac MRI data provide an accurate and reproducible measurement of stroke volume, ejection fraction, cardiac output, ventricular volumes and ventricular function, thereby providing a reliable method to monitor the effects of acupuncture on the cardiovascular system and to visualise the heart non-invasively with high spatial and temporal resolution. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | This pathway appears to contribute to the long-lasting, acupuncture-mediated attenuation of sympathetic premotor outflow and excitatory cardiovascular reflex responses. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | To determine the underlying mechanisms of the effect of acupuncture on the nervous system, the roles of several neurotransmitters in cardiovascular-related regions of the medulla have been examined. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | During and after acupuncture stimulation, neurotransmitters and neuromodulators such as nociceptin, GABA and opioids, including endorphins and enkephalins acting through μ and δ-opioid receptors in the RVLM, inhibit sympathetic outflow and the resulting cardiovascular sympathoexcitatory response. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | In addition, acetylcholine, endocannabinoids and glutamate appear to contribute to the effect of acupuncture on cardiovascular function in various regions of the hypothalamus, midbrain and medulla. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | Acupuncture thus probably modulates sympathoexcitatory responses by releasing neurotransmitters that inhibit the activity of bulbospinal presympathetic neurons, and it controls the peripheral sympathetic tone and cardiovascular activities. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | Opioid release from the central nervous system and cardiovascular reflex changes are assumed to have physiological roles in eliciting the effects of acupuncture at PC6. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | The beneficial effect of acupuncture at PC6 on hypertension, cardiac ischaemia and arrhythmias is achieved by reduced sympathetic outflow mediated by the excitation of nucleus raphe obscurus neurons, which inhibit cardiovascular neurons in the RVLM that, in turn, activate opioid, GABA and 5-hydroxytryptamine (5-HT) receptors. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | It is therefore likely that the medullary raphe nuclei, particularly the nucleus raphe pallidus, process somatic signals during acupuncture and participate in acupuncture-mediated modulation effects on cardiovascular function by an opioid or serotonergic mechanism. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 22378585 | Acupuncture at PC6 can stimulate the long-loop pathway to activate the ARC, VLPAG and nucleus raphe pallidus, which inhibit the RVLM to reduce the cardiovascular sympathoexcitatory reflex response through the upregulation of GABA, opioids, 5-HT, NO and NOS. | Acupunct Med. 2012 Mar;30(1):47-50. doi: 10.1136/acupmed-2011-010060. | Cardiovascular | Review |
| 23260431 | Cardiovascular responses elicited by acupuncture have been reported to be mediated by direct and indirect projections of the Arc to the RVLM. | Auton Neurosci. 2013 Apr;175(1-2):38-50. doi: 10.1016/j.autneu.2012.10.016. Epub 2012 Dec 19. | Cardiovascular | Review |
| 23260431 | Finally, the role of Arc in mediating the cardiovascular effects of acupuncture is discussed. | Auton Neurosci. 2013 Apr;175(1-2):38-50. doi: 10.1016/j.autneu.2012.10.016. Epub 2012 Dec 19. | Cardiovascular | Review |
| 23260431 | Role of the Arc in cardiovascular effects of acupuncture | Auton Neurosci. 2013 Apr;175(1-2):38-50. doi: 10.1016/j.autneu.2012.10.016. Epub 2012 Dec 19. | Cardiovascular | Review |
| 23260431 | Manual or electroacupuncture (EA) is being increasingly accepted as an alternative and/or adjunctive therapy for the treatment of cardiovascular diseases such as hypertension (Review:). | Auton Neurosci. 2013 Apr;175(1-2):38-50. doi: 10.1016/j.autneu.2012.10.016. Epub 2012 Dec 19. | Cardiovascular | Review |
| 24523823 | It is believed that acupuncture may regulate the cardiovascular system through a complicated brain network from the cortical level, the hypothalamus, and the brainstem. | Evid Based Complement Alternat Med. 2014;2014:568429. doi: 10.1155/2014/568429. Epub 2014 Jan 2. | Cardiovascular | Review |
| 24723957 | Acupuncture has been theorized to lower reflex-induced hypertension by modulating the activity of cardiovascular presympathetic neurons in the rostral ventrolateral medulla. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Cardiovascular | Review |
| 24723957 | 's study proved that short-term (one month) acupuncture did not decrease BP significantly and acupuncture may regulate the cardiovascular system through a complicated brain network from the cortical level, the hypothalamus, and the brainstem. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Cardiovascular Blood Pressure | Review |
| 28664077 | Acupuncture needling can affect multiple systems in the body including the nervous system, immune system, and cardiovascular system, so more than one research method is necessary. | Integr Med Res. 2014 Jun;3(2):41-48. doi: 10.1016/j.imr.2014.03.003. Epub 2014 Apr 1. | Immunity Cardiovascular | Review |
| 29063107 | This observation led us to conclude that acupuncture might lower sympathetic outflow and hence decrease the magnitude of the cardiovascular reflex sympathetically mediated vasoconstriction. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Cardiovascular | Review |
| 29063107 | These point specific cardiovascular actions of acupuncture define locations on peripheral nerves that exert the largest blood pressure lowering responses as well as control points that have little or no effect on cardiovascular function. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Cardiovascular Blood Pressure | Review |
| 29063107 | Low intensity, low frequency electroacupuncture was applied once weekly for eight weeks to active points with demonstrated cardiovascular actions and compared either longitudinally or in a cross-over design to points that had little or no cardiovascular action in experimental studies. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Cardiovascular | Review |
| 29063107 | This study was designed to be translatable to clinical practice, incorporating once weekly application of low frequency, low intensity 30 min electroacupuncture for eight weeks and stimulating a set of points that influence cardiovascular function. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Cardiovascular | Review |
| 29063107 | Acupuncture influences neurons that regulate cardiovascular function in the paraventricular nucleus (PVN), arcuate nucleus (ARC), ventrolateral periaqueductal gray (vlPAG), nucleus raphe-pallidus (NR-P), rostral ventrolateral medullar (rVLM), and neurotransmitters beta-endorphin (β-End), acetylcholine (ACh), L-glutamate (L-Glu), gamma-butyric acid (GABA), enkephalin (Enk), serotonin 1A receptor (5-HT1A) that participate in the central neural processing during EA. | Sheng Li Xue Bao. 2017 Oct 25;69(5):587-597. | Cardiovascular | Review |
| 29844696 | Here, we review a broad range of experimental studies demonstrating anti-inflammatory effects of electroacupuncture in pathologic animal models of cardiovascular and visceral organs and also ischemic brains. | J Inflamm Res. 2018 May 17;11:227-237. doi: 10.2147/JIR.S141198. eCollection 2018. | Cardiovascular | Review |
| 29844696 | Evidence demonstrating the involvement of autonomic nerve activity in acupuncture action largely comes from physiological studies analyzing cardiovascular responses and gastrointestinal (GI) motility in experimental animals and humans. | J Inflamm Res. 2018 May 17;11:227-237. doi: 10.2147/JIR.S141198. eCollection 2018. | Cardiovascular | Review |
| 29844696 | Longhurst and Tjen-A-Looi reported that acupuncture stimulation regulated cardiovascular function (blood pressure), whereby neurotransmitter release and neuromodulation in the hypothalamus and several cardiovascular nuclei in the brain stem mediated acupuncture effects. | J Inflamm Res. 2018 May 17;11:227-237. doi: 10.2147/JIR.S141198. eCollection 2018. | Cardiovascular Blood Pressure | Review |
| 30809158 | Serious and potentially life-threatening acupuncture-related complications, including transmission of infections, pneumothorax, cardiovascular lesions, and hemorrhage or hematomas in the central nervous system (CNS), are very rarely reported. | Front Psychiatry. 2019 Feb 12;10:14. doi: 10.3389/fpsyt.2019.00014. eCollection 2019. | Cardiovascular Bleeding | Review |
| 30855351 | Finally, recent researches showed that the endocannabinoid system has been involved in many of the various therapeutic effects induced by acupuncture, the biological effects including analgesia, neuroprotection and cardiovascular regulation shared by both acupuncture and the endocannabinoid system. | Chin Med J (Engl). 2019 Mar 20;132(6):707-715. doi: 10.1097/CM9.0000000000000123. | Neuroprotection Cardiovascular | Review |
| 30984420 | The research found that acupuncture can inhibit rVLM premotor sympathetic cardiovascular neurons and can attenuate visceral sympathoexcitatory reflexes through opioid-mediated inhibition of aspartic acid (Asp) and glutamic acid (Glu) action in the rVLM. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Cardiovascular | Review |
| 30984420 | Acupuncture can affect the sympathetic outflow and cardiovascular function through the enkephalin mechanism. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Cardiovascular | Review |
| 30984420 | Therefore, acupuncture can regulate the cortical level, the hypothalamus, and the brain stem, along with other complex brain networks, so as to reduce the autonomic nervous response and regulating the cardiovascular system, thus resulting in an antihypertensive effect. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Cardiovascular | Review |
| 31118954 | In animal models of various diseases, such as neurological disease, cardiovascular disease, myopathy, and pain, a number of miRNAs were altered after administration of electroacupuncture or manual acupuncture. | Evid Based Complement Alternat Med. 2019 Apr 16;2019:3051472. doi: 10.1155/2019/3051472. eCollection 2019. | Cardiovascular | Review |
| 31118954 | The changes of miRNA by acupuncture in the cardiovascular-related diseases are summarized in Table 1. | Evid Based Complement Alternat Med. 2019 Apr 16;2019:3051472. doi: 10.1155/2019/3051472. eCollection 2019. | Cardiovascular | Review |
| 31118954 | By analyzing literatures, it was suggested that miR-145, which was increased by acupuncture in hypertension rat model, plays a significant role in different cardiovascular diseases. | Evid Based Complement Alternat Med. 2019 Apr 16;2019:3051472. doi: 10.1155/2019/3051472. eCollection 2019. | Cardiovascular | Review |
| 31379957 | The signal transduction pathway of acupuncture has been mentioned with respect to many diseases, including neurological, cardiovascular, metabolic, and gynecological diseases. | Evid Based Complement Alternat Med. 2019 Jul 11;2019:2909632. doi: 10.1155/2019/2909632. eCollection 2019. | Cardiovascular | Review |
| 31467579 | At present, the correlation between electroacupuncture regulation and MAPK-related signaling pathways is mainly focused on the anti-inflammatory and analgesic effects, protection against injury, regulation of gastrointestinal functions, and prevention and treatment of cardiovascular and cerebrovascular diseases, skin diseases, and knee joint diseases. | Evid Based Complement Alternat Med. 2019 Jul 31;2019:8138017. doi: 10.1155/2019/8138017. eCollection 2019. | Analgesic Effect Cardiovascular | Review |
| 31467579 | Effects of Electroacupuncture on Cardiovascular and Cerebrovascular Diseases | Evid Based Complement Alternat Med. 2019 Jul 31;2019:8138017. doi: 10.1155/2019/8138017. eCollection 2019. | Cardiovascular | Review |
| 31467579 | It is presumed that this may be an important molecular mechanism for acupuncture and moxibustion to regulate blood pressure and improve cardiovascular remodeling. | Evid Based Complement Alternat Med. 2019 Jul 31;2019:8138017. doi: 10.1155/2019/8138017. eCollection 2019. | Cardiovascular Blood Pressure | Review |
| 31467579 | (4) In the treatment of cardiovascular and cerebrovascular diseases, as for the intervention of electroacupuncture on ischemia-reperfusion injury, the three pathways involved in the MAPK cascade transduction pathway, namely, ERK, JNK, and p38, are mainly involved. | Evid Based Complement Alternat Med. 2019 Jul 31;2019:8138017. doi: 10.1155/2019/8138017. eCollection 2019. | Cardiovascular | Review |
| 32523527 | Although many mechanisms underlying the effects of acupuncture on cardiovascular function have been identified, further investigation is warranted. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Cardiovascular | Review |
| 32523527 | Clinical trials and animal experiments have been conducted to investigate cardiovascular vagal regulation by acupuncture (Hsu et al.,; La Marca et al.,; Gao et al.,). | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Cardiovascular | Review |
| 32684734 | When it comes to the effects of acupuncture on modulating the cardiovascular system, stimulations of the limbs, chest, and abdomen all produce a similar effect in terms of heart rate and blood pressure, yet whether the effect is excited or suppressed depends on the intensity of the stimulus (or what type of fiber is activated) and the tissue structure (skin or muscle). | World J Gastroenterol. 2020 Jun 21;26(23):3182-3200. doi: 10.3748/wjg.v26.i23.3182. | Heart Rate Cardiovascular Blood Pressure | Review |
| 34489268 | Medical competence is particularly required for the indication of acupuncture in patients at high risk of AEs or those in which AEs could lead to particular aversive outcomes, such as pregnant women, elderly and patients with cardiovascular comorbidities. | BMJ Open. 2021 Sep 6;11(9):e045961. doi: 10.1136/bmjopen-2020-045961. | Cardiovascular | Review |
| 34675729 | Given its non-pharmacological basis, acupuncture also obviates the concerns with respect to toxicity and AEs that commonly occur when using hypnotics/sedatives, such as hangover, tolerance, increased alertness, and even endocrinological, hematological or cardiovascular events, and concerns regarding common side effects of contemporary antidepressive agents, such as dry mouth, cardiovascular/gastrointestinal side effects, seizure, bleeding, sexual dysfunction, weight gain, and even suicidality. | Nat Sci Sleep. 2021 Oct 12;13:1823-1863. doi: 10.2147/NSS.S332474. eCollection 2021. | Cardiovascular Endocrinology Toxic Side Effects Side Effects Bleeding | Review |
| 35281899 | Accumulating evidences indicate that acupuncture is safe and has great clinical efficacy in the treatment of various diseases, including gastrointestinal diseases, neurodegenerative diseases, cardiovascular diseases, chronic pain, insomnia and CKD. | Front Pharmacol. 2022 Feb 25;13:816025. doi: 10.3389/fphar.2022.816025. eCollection 2022. | Cardiovascular Insomnia | Review |
| 35449821 | It has already been utilized as a method of providing insight into research in contemporary medicine and traditional Chinese medicine-related topics, such as yoga, acupuncture, Chinese medicinals, cancers, and cardiovascular diseases. | Evid Based Complement Alternat Med. 2022 Apr 11;2022:7705256. doi: 10.1155/2022/7705256. eCollection 2022. | Cardiovascular | Review |
| 35725779 | Animal models showed that that electroacupuncture leads to the inhibition of the neuronal network that affect the cardiovascular sympathetic neurons, reducing blood pressure. | Blood Rev. 2022 Nov;56:100985. doi: 10.1016/j.blre.2022.100985. Epub 2022 Jun 13. | Cardiovascular Blood Pressure | Review |
| 36107536 | The decline in mortality of cardiovascular diseases in western countries is closely related to the effective control of risk factors, which indicates a new feasible approach for the prevention of stroke.. More than thousands of years, acupuncture in China has been used as a traditional medical resource to ameliorate various diseases including stroke and other nervous system diseases. | Medicine (Baltimore). 2022 Sep 2;101(35):e30086. doi: 10.1097/MD.0000000000030086. | Cardiovascular | Review |
| 36148057 | In the past, for a long time, acupuncture was used to treat neurological diseases (including hemiplegic paralysis, facial paralysis, insomnia, and cephalalgia), orthopedic diseases (such as protrusion of the lumbar intervertebral disc, cervical spondylosis, and knee osteoarthritis), and gastrointestinal diseases (such as constipation, diarrhea, and hiccup singulation); cardiovascular diseases were not included in the spectrum of common ailments treated by acupuncture. | Front Cardiovasc Med. 2022 Sep 6;9:920491. doi: 10.3389/fcvm.2022.920491. eCollection 2022. | Cardiovascular Insomnia | Review |
| 36148057 | Due to the characteristics of acute onset, severe condition, and high mortality of cardiovascular diseases, as a complementary and alternative therapy, the therapeutic effect of acupuncture in cardiovascular diseases has been neglected in the past. | Front Cardiovasc Med. 2022 Sep 6;9:920491. doi: 10.3389/fcvm.2022.920491. eCollection 2022. | Cardiovascular | Review |
| 36148057 | In recent years, with the development of the mechanism of acupuncture in analgesia, anti-inflammatory and nerve regulation, and effects in withdrawal syndrome, weight loss, and blood pressure regulation, acupuncture has become a potential therapeutic method for reducing cardiovascular disease risk factors, reducing the number of acute attacks, improving the results of electrocardiography, and alleviating anxiety and depression. | Front Cardiovasc Med. 2022 Sep 6;9:920491. doi: 10.3389/fcvm.2022.920491. eCollection 2022. | Cardiovascular Anxiety Blood Pressure Depression | Review |
| 36340786 | Because of the difficulty in overcoming side effects, including hypersensitivity reactions, cardiovascular disease, and cerebrovascular disease, more clinical studies are required to make acupuncture an alternative strategy to target CGRP. | Front Neurosci. 2022 Oct 20;16:1022455. doi: 10.3389/fnins.2022.1022455. eCollection 2022. | Cardiovascular Side Effects | Review |
| 36532179 | Acupuncture in treating cardiovascular disease complicated with depression: A systematic review and meta-analysis | Front Psychiatry. 2022 Dec 1;13:1051324. doi: 10.3389/fpsyt.2022.1051324. eCollection 2022. | Cardiovascular Depression | Review |
| 36532179 | Many clinical studies have shown that acupuncture is good at relieving depression and improving cardiovascular symptoms, but it is unclear whether acupuncture can affect psycho-cardiology disease. | Front Psychiatry. 2022 Dec 1;13:1051324. doi: 10.3389/fpsyt.2022.1051324. eCollection 2022. | Cardiovascular Depression | Review |
| 36570846 | Using a non-invasive cardiovascular autonomic function test, it was found that electroacupuncture at ashi points in the lower back resulted in analgesia, restored reduced vagal tone, and increased sympathetic activity in patients with CLBP. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Cardiovascular | Review |
| 36570846 | Responses of cardiovascular barosensitive VLM neurons evoked by splanchnic nerve stimulation were reduced by electroacupuncture and subsequently restored by opioid receptor blockade in the PVN. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Cardiovascular | Review |
| 36570846 | In summary, the present review concentrated mainly on the influence of the midbrain and brain stem in acupuncture-mediated effects on the cardiovascular system, as shown in Figure 2. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Cardiovascular | Review |
| 36570846 | Acupuncture activates the PVN hypothalamic nuclei and the PAG midbrain nuclei, thereby inhibiting the medulla oblongata VLM nucleus before activating sympathetic neurons and their subsequent reduction of cardiovascular excitation. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Cardiovascular | Review |
| 36570846 | Moreover, acupuncture stimulates centers associated with the vagus nerves, including the hypothalamic and midbrain nuclei, thereby regulating cardiovascular function. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Cardiovascular | Review |
| 36570846 | Hypothetical diagram of the central nervous circuits in which autonomic nerves contribute to regulating cardiovascular function by acupuncture. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Cardiovascular | Review |
| 36570846 | Based on the underlying functional pathways and physiological roles of the ANS, we speculate that the ANS plays a significant role in the central nervous circuit activated by acupuncture, leading to the modulation of cardiovascular and gastrointestinal functions, as well as anti-inflammatory and analgesic functions. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Cardiovascular | Review |
| 36570846 | However, further investigation is needed into whether acupuncture can regulate the cardiovascular and gastrointestinal systems by regulating the prosencephalon autonomic nuclei. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Cardiovascular | Review |
| 36570846 | For instance, acupuncture treats cardiovascular disease by activating the hypothalamic PVN nuclei and the PAG midbrain nuclei, together with inhibition of medulla oblongata VLM nucleus, and finally, inhibition of cardiac sympathetic nerve excitability. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Cardiovascular | Review |
| 36570846 | Furthermore, acupuncture activates the vagus center and efferent vagus nerve to regulate cardiovascular function. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Cardiovascular | Review |
| 36570846 | Current knowledge indicates that the central autonomic nuclei are implicated in acupuncture modulation of the gastrointestinal and cardiovascular systems. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Cardiovascular | Review |
| 36570846 | For example, electroacupuncture at ST36 and PC6 can improve gastrointestinal motility in rats with gastric dilatation by stimulating vagus nerves; and electroacupuncture at PC5 and PC6 can reduce cardiovascular excitatory response and regulate blood pressure by the stimulating the vagus nerve and inhibiting sympathetic nerves. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Cardiovascular Blood Pressure | Review |
| 36607887 | However, AA, which is developed from the traditional Chinese acupuncture analgesia, has an optimal analgesic effect by affecting the production and release of neurotransmitters, significantly controlling the increase in blood pressure and heart rate during surgery and reduces the cardiovascular response after cervical plexus block. | Medicine (Baltimore). 2023 Jan 6;102(1):e32582. doi: 10.1097/MD.0000000000032582. | Analgesic Effect Heart Rate Cardiovascular Blood Pressure | Review |
| 36864974 | Moreover, he was a specialist in cardiovascular responses focused on acupuncture treatment of hypertension. | Cardiovasc Diagn Ther. 2023 Feb 28;13(1):67-82. doi: 10.21037/cdt-22-480. Epub 2022 Dec 15. | Cardiovascular | Review |
| 37260441 | Acupuncture has clinical efficacy in the treatment of cardiovascular diseases, epilepsy, anxiety, circadian rhythm disorders, PCOS, low reproductive capacity, and autonomic nervous system diseases. | Front Endocrinol (Lausanne). 2023 May 16;14:956772. doi: 10.3389/fendo.2023.956772. eCollection 2023. | Cardiovascular Anxiety | Review |
| 37727325 | One of the strengths of our work is that it has summarized the effects on cardiovascular factors of a broad range of AS, including traditional ways such as ear-acupuncture and modern ways such as electrical tVNS. | Front Neurosci. 2023 Sep 1;17:1227858. doi: 10.3389/fnins.2023.1227858. eCollection 2023. | Cardiovascular | Review |
| 37810368 | Using Cytoscape 3.6.0 software for the visual display, a complex network analysis was performed of acupuncture points and symptoms related to the respiratory, digestive, nervous, and cardiovascular systems and psycho-psychological disorders of patients with COVID-19. | Acupunct Herb Med. 2023 Jun;3(2):83-95. doi: 10.1097/HM9.0000000000000062. Epub 2023 Mar 13. | Gastrointestinal Tract Cardiovascular | Review |
| 37810368 | Acupuncture for the treatment of COVID-19 combined with cardiovascular and other underlying diseases | Acupunct Herb Med. 2023 Jun;3(2):83-95. doi: 10.1097/HM9.0000000000000062. Epub 2023 Mar 13. | Cardiovascular | Review |
| 37810368 | The mechanism of acupuncture in treating cardiovascular diseases is complex. | Acupunct Herb Med. 2023 Jun;3(2):83-95. doi: 10.1097/HM9.0000000000000062. Epub 2023 Mar 13. | Cardiovascular | Review |
| 37810368 | Second, owing to the lack of case reports on acupuncture treatment for COVID-19 combined with the cardiovascular system and other basic diseases, the principles of acupoint selection for acupuncture treatment of cardiovascular system-related symptoms have not been summarized, and there is no agreement on the treatment course of acupuncture for COVID-19-related symptoms. | Acupunct Herb Med. 2023 Jun;3(2):83-95. doi: 10.1097/HM9.0000000000000062. Epub 2023 Mar 13. | Cardiovascular | Review |
| 38162142 | Acupuncture has been used for centuries as an important component of Chinese medicine for the treatment of elevated blood pressure in China and has been widely used internationally for the treatment of cardiovascular and cerebrovascular diseases. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Cardiovascular Blood Pressure | Review |
| 38162142 | Theoretically, acupuncture reduces reflex hypertension by regulating the activity of precardiovascular sympathetic neurons on the ventrolateral (RVLM) end of the medulla oblongata. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Cardiovascular | Review |
| 38162142 | Generally speaking, serving as a non-pharmacological intervention, acupuncture has been used by clinicians to improve and treat a variety of cardiovascular diseases and also has the advantage of reducing treatment costs, adverse effects, and complications. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Cardiovascular Adverse Reactions | Review |
| 38162142 | Therefore, to confirm the evaluation of the efficacy of acupuncture in elderly patients with hypertension, more attention should be paid to endpoint events, such as distant-related cardiovascular events and target organ damage, in addition to the observation of blood pressure values. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Cardiovascular Blood Pressure | Review |
| 22073889 | CONCLUSION: Acupuncture-assisted anesthesia can decrease the dosage of general anesthetics, and effectively restrain cardiovascular stress reaction during trachea extubation in pulmonery lobectomy patients. | Zhen Ci Yan Jiu. 2011 Oct;36(5):361-5. | Cardiovascular Stress Response | Clinic |
| 22073889 | CONCLUSION: Acupuncture-assisted anesthesia can decrease the dosage of general anesthetics, and effectively restrain cardiovascular stress reaction during trachea extubation in pulmonery lobectomy patients. | Zhen Ci Yan Jiu. 2011 Oct;36(5):361-5. | Cardiovascular Stress Response | Clinic |
| 22330010 | Cardiovascular parameters were stable in all three groups, and no complications were recorded. | Colorectal Dis. 2012 Aug;14(8):e486-91. doi: 10.1111/j.1463-1318.2012.02984.x. | Cardiovascular | Clinic |
| 22611431 | In contrast, electoacupuncture at 2xe2x80x934xe2x80x89Hz suppresses cardiovascular sympathetic reactions. | Evid Based Complement Alternat Med. 2012;2012:727121. doi: 10.1155/2012/727121. Epub 2012 Jan 31. | Cardiovascular | Clinic |
| 27688791 | The Global Burden of Disease study estimates 62% of stroke, 49% of ischemic heart disease, and 14% of other cardiovascular disease can be attributable to mean systolic blood pressure levels >115xe2x80x89mmHg worldwide. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Cardiovascular Blood Pressure | Clinic |
| 27688791 | Acupuncture, one of the oldest and most commonly used forms of alternative medicine, has existed for 2500 years, which has been reported to have potential for treating cardiovascular diseases, including EH. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Cardiovascular | Clinic |
| 27688791 | But the cardiovascular center is mainly located in the medulla oblongata and hypothalamus, and these areas are not in the DMN. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Cardiovascular | Clinic |
| 27688791 | Many studies had shown that the hypothalamus may be the key role in the central nervous system (CNS) in cardiovascular regulation, especially the supraoptic (SO) nucleus and paraventricular (Pa) nucleus of the hypothalamus, which can produce the vasopressin. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Cardiovascular | Clinic |
| 27688791 | As SO and Pa may be the key role in the CNS in cardiovascular regulation, we selected them as the seed point regions to explore modulated brain network changes underlying acupuncture hypertension treatment. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Cardiovascular | Clinic |
| 27688791 | The role of supraoptic (SO) nucleus and paraventricular (Pa) nucleus of the hypothalamus was secreting vasopressin (AVP), which could interact with neurons of cardiovascular activity, affecting cardiovascular activity, as well as influencing the body's baroreflex sensitivity. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Cardiovascular | Clinic |
| 27688791 | Study demonstrated that the limbic system had an important role in cardiovascular center. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Cardiovascular | Clinic |
| 27688791 | Although the role of cerebellum in cardiovascular center was unclear, there was an animal experiment that showed that the cerebellum had a relationship with nitric oxide synthase activity, indirectly related to blood pressure regulation. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Cardiovascular Blood Pressure | Clinic |
| 27688791 | (3) The MRI we used did not involve the brain stem, which is one of the cardiovascular control centers. | Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4. | Cardiovascular | Clinic |
| 30425466 | Intraoperative circulatory system was maintained by adjusting the anesthesia depth (controlling BIS, 40xe2x80x9360) and administering transfusions or cardiovascular agents as necessary. | Clin Interv Aging. 2018 Oct 24;13:2127-2134. doi: 10.2147/CIA.S183698. eCollection 2018. | Cardiovascular Circulation | Clinic |
| 32062864 | The exclusion criteria for randomization were as follows: American Society of Anesthesiologists status III, IV, or V; recent use of TEAS or acupuncture; severe comorbidities including prexe2x80x90existing coagulopathy, hypertension (systolic pressurexe2x80x89xe2x89xa5xe2x80x89180xe2x80x89mmHg and/or diastolic pressurexe2x80x89xe2x89xa5xe2x80x89110xe2x80x89mmHg), cardiovascular disease, and diabetes; history of chronic pain; and history of opioid or alcohol abuse. | Thorac Cancer. 2020 Apr;11(4):928-934. doi: 10.1111/1759-7714.13343. Epub 2020 Feb 16. | Cardiovascular | Clinic |
| 36749304 | The excluded criteria included (1) a history of neurological and psychiatric disorders, or head trauma with loss of consciousness; (2) serious renal, cardiovascular, respiratory or other organic diseases; (3) any contraindications to rsxe2x80x90fMRI scanning (such as defibrillator, cardiac pacemaker, metal stents or electronic implant, intraocular mental foreign body, claustrophobia, and hyperpyrexia); (4) unwillingness to sign the consent form; (5) having received acupuncture/EA in the past three months. | Brain Behav. 2023 Mar;13(3):e2913. doi: 10.1002/brb3.2913. Epub 2023 Feb 7. | Cardiovascular Kidney | Clinic |
| 29773696 | The exclusion criteria were as follows: serious disease that could cause LBP (eg, cancer, vertebral fracture, spinal infection, inflammatory spondylitis, cauda equina compression); chronic disease that could influence the effects or results of treatment (eg, severe cardiovascular disease, diabetic neuropathy, dementia or epilepsy); progressive neurological deficit or severe neurological symptoms; conditions inappropriate or unsafe for EA (eg, due to haemorrhagic disease, clotting disorder, history of having received anticoagulant therapy within the preceding 3 weeks, severe diabetes with risk of infection or severe cardiovascular disease); pain not caused by spinal or soft tissue disease, such as ankylosing spondylitis, fibromyalgia, rheumatoid arthritis or gout; pregnancy or planning to become pregnant; psychiatric disease; participation in another clinical trial; inability to provide written informed consent and ineligibility for inclusion in the study in the opinion of the investigators. | BMJ Open. 2018 May 17;8(5):e018464. doi: 10.1136/bmjopen-2017-018464. | Cardiovascular | Clinic |
| 16173479 | OBJECTIVE: To compare the effects of acupuncture (AP), electroacupuncture (EA), and transcutaneous cranial electrical stimulation (TCES) with high-frequency intermittent currents on the minimum alveolar concentration (MAC) of isoflurane and associated cardiovascular variables in dogs. | Am J Vet Res. 2005 Aug;66(8):1364-70. doi: 10.2460/ajvr.2005.66.1364. | Cardiovascular | Mechanism |
| 21749999 | Cardiovascular and respiratory parameters were recorded for both groups during operation. | Br J Anaesth. 2011 Oct;107(4):612-8. doi: 10.1093/bja/aer199. Epub 2011 Jul 12. | Cardiovascular | Mechanism |
| 11405917 | Cardiovascular beneficial effects of electroacupuncture at Neiguan (PC-6) acupoint in anesthetized open-chest dog. | Jpn J Physiol. 2001 Apr;51(2):231-8. doi: 10.2170/jjphysiol.51.231. | Cardiovascular | Mechanism |
| 11405917 | Neiguan electroacupuncture (EA) has been believed to affect cardiovascular function and used in traditional Chinese medicine to improve or treat a wide range of health conditions and diseases, including angina pectoris, myocardial infarction, hypertension, and hypotension. | Jpn J Physiol. 2001 Apr;51(2):231-8. doi: 10.2170/jjphysiol.51.231. | Cardiovascular | Mechanism |
| 11405917 | However, few physiological studies have assessed the beneficial effects of Neiguan EA on the cardiovascular function. | Jpn J Physiol. 2001 Apr;51(2):231-8. doi: 10.2170/jjphysiol.51.231. | Cardiovascular | Mechanism |
| 11405917 | In the present study, we investigated its effects on the cardiovascular function in normal open-chest dogs under pentobarbital and fentanyl anesthesia. | Jpn J Physiol. 2001 Apr;51(2):231-8. doi: 10.2170/jjphysiol.51.231. | Cardiovascular | Mechanism |
| 11405917 | Neiguan EA at 40 Hz, however, increased these cardiovascular variables by 10 to 15%, especially end-systolic elastance (Ees) by 40% (p<0.05) over 15 to 60 min. | Jpn J Physiol. 2001 Apr;51(2):231-8. doi: 10.2170/jjphysiol.51.231. | Cardiovascular | Mechanism |
| 11405917 | After Neiguan EA was stopped at 1 h, these facilitated cardiovascular variables decreased below the pre-EA level. | Jpn J Physiol. 2001 Apr;51(2):231-8. doi: 10.2170/jjphysiol.51.231. | Cardiovascular | Mechanism |
| 7248823 | Reversal by acupuncture of cardiovascular depression induced with morphine during halothane anaesthesia in dogs. | Can Anaesth Soc J. 1981 Mar;28(2):129-35. doi: 10.1007/BF03007256. | Cardiovascular Depression | Mechanism |
| 7248823 | The cardiovascular effects of morphine sulphate and/or acupuncture by means of electrocautery at Jen Chung (Go-26) were studied in 35 dogs. | Can Anaesth Soc J. 1981 Mar;28(2):129-35. doi: 10.1007/BF03007256. | Cardiovascular | Mechanism |
| 7248823 | Stimulation of this acupuncture locus could be helpful in resuscitating patients whose cardiovascular system is depressed by morphine and/or halothane anaesthesia. | Can Anaesth Soc J. 1981 Mar;28(2):129-35. doi: 10.1007/BF03007256. | Cardiovascular | Mechanism |
| 15777754 | We conclude that EA ST 36 induces nNOS expression in the gracile nucleus and mNTS, and enhanced nNOS-NO in the nuclei may modify central cardiovascular regulation, which contribute to hypotensive effects of acupuncture. | Brain Res. 2005 Mar 10;1037(1-2):70-7. doi: 10.1016/j.brainres.2004.12.029. | Cardiovascular | Mechanism |
| 34892981 | BACKGROUND: Polycystic ovary syndrome (PCOS) affects 8%-15% of reproductive-age women and is associated with reproductive disorders, abdominal obesity, hyperinsulinemia, insulin resistance, type 2 diabetes, and cardiovascular diseases. | Acupunct Med. 2022 Aug;40(4):347-359. doi: 10.1177/09645284211056663. Epub 2021 Dec 10. | Cardiovascular | Mechanism |
| 34892981 | Acupuncture, as a traditional physical therapy method, could affect various metabolic disorders such as obesity, hyperplasia, gout, and cardiovascular and cerebrovascular diseases in clinical practice. | Acupunct Med. 2022 Aug;40(4):347-359. doi: 10.1177/09645284211056663. Epub 2021 Dec 10. | Cardiovascular | Mechanism |
| 20398952 | Non-alcoholic fatty liver disease (NAFLD) has gained extensive research attention, and the relationship with cardiovascular disease is of great clinical interest. | Arch Gerontol Geriatr. 2011 Mar-Apr;52(2):164-6. doi: 10.1016/j.archger.2010.03.009. Epub 2010 Apr 15. | Cardiovascular | Mechanism |
| 26566622 | OBJECTIVES: To investigate the effect of electroacupuncture (EA) at LR3 on blood pressure (BP) and cardiovascular remodelling and hypertrophy in male spontaneously hypertensive rats (SHRs). | Acupunct Med. 2016 Jun;34(3):201-8. doi: 10.1136/acupmed-2015-010782. Epub 2015 Nov 13. | Cardiovascular Blood Pressure | Mechanism |
| 26566622 | Thus, EA is a potentially promising intervention to treat cardiovascular remodelling secondary to hypertension. | Acupunct Med. 2016 Jun;34(3):201-8. doi: 10.1136/acupmed-2015-010782. Epub 2015 Nov 13. | Cardiovascular | Mechanism |
| 22984478 | Functional studies have demonstrated the involvement of PVN in the control of fluid electrolyte homeostasis, feeding behavior, cardiovascular regulation, and stress adaptation. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Cardiovascular | Mechanism |
| 22984478 | A number of epidemiological and clinical data suggests that antioxidant-rich diets or natural antioxidants reduce blood pressure and cardiovascular risk, and animal studies have also shown the antihypertensive activity of antioxidants. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Cardiovascular Blood Pressure | Mechanism |
| 25695055 | In the past 40 years, the mechanistic studies of acupuncture mainly focus on (1) the neural pathways involved in inflammation, pain, and cardiovascular effects; (2) the involvement of the connective tissues and their association with neural regulation; and (3) other molecular pathways that are involved in neural response to acupuncture. | Biomed Res Int. 2015;2015:249013. doi: 10.1155/2015/249013. Epub 2015 Jan 28. | Cardiovascular | Mechanism |
| 35482778 | Accumulating evidence indicated that insomnia was associated with a wide range of negative health consequences, such as mental disorder, cardiovascular dysfunction, type 2 diabetes, and obesity. | PLoS One. 2022 Apr 28;17(4):e0267843. doi: 10.1371/journal.pone.0267843. eCollection 2022. | Cardiovascular Insomnia | Mechanism |
| 26386034 | Classically PC6 is used for cardiovascular disease, while CV12 is used for gastrointestinal disease, although both points are classically indicated for nausea and vomiting. | Acupunct Med. 2016 Apr;34(2):120-6. doi: 10.1136/acupmed-2015-010833. Epub 2015 Sep 17. | Cardiovascular Nausea and Vomiting | Mechanism |
| 29123119 | The acupoints are prescribed most frequently for cardiac disorders or have been shown to be effective in cardiovascular disorders. | Sci Rep. 2017 Nov 9;7(1):15214. doi: 10.1038/s41598-017-14359-z. | Cardiovascular | Mechanism |
| 29123119 | In support of these findings, multiple studies have shown that acupuncture stimulation at PC6 can improve or treat cardiovascular disorders, including hypertension, myocardial infarction or hypotension, in humans or experimental animals. | Sci Rep. 2017 Nov 9;7(1):15214. doi: 10.1038/s41598-017-14359-z. | Cardiovascular | Mechanism |
| 29123119 | Similarly, a previous study revealed that traditional or electrical acupuncture applied to the PC5-6 acupoints activate small fibres to evoke cardiovascular effects. | Sci Rep. 2017 Nov 9;7(1):15214. doi: 10.1038/s41598-017-14359-z. | Cardiovascular | Mechanism |
| 26991319 | In addition, AS at the abdomen acupoint ST25 has been shown to induce c-Fos signals in neurons at the rostroventrolateral medulla (RVLM), a brain center that sends out axons to the spinal cord for sympathetic regulation of cardiovascular functions. | PLoS One. 2016 Mar 18;11(3):e0151882. doi: 10.1371/journal.pone.0151882. eCollection 2016. | Cardiovascular | Mechanism |
| 15046638 | For example, women with PCOS develop cardiovascular abnormalities such as hypertension. | Reprod Biol Endocrinol. 2004 Mar 26;2:16. doi: 10.1186/1477-7827-2-16. | Cardiovascular | Mechanism |
| 15046638 | Women with PCOS are known to be candidates for increased cardiovascular risk, and it has recently been shown that they have diastolic dysfunction, an early indicator of hypertension. | Reprod Biol Endocrinol. 2004 Mar 26;2:16. doi: 10.1186/1477-7827-2-16. | Cardiovascular | Mechanism |
| 24980520 | It has emerged as a promising new drug target for treatment metabolic disorders, including obesity, type 2 diabetes and cardiovascular disease. | BMC Complement Altern Med. 2014 Jun 30;14:211. doi: 10.1186/1472-6882-14-211. | Cardiovascular | Mechanism |
| 32956833 | Finally, to determine whether acupuncture at Neuro-Sps excites rVLM neurons, known as an important site for cardiovascular regulation, and if acupuncture effects on rVLM neurons might be inhibited by subcutaneous injection of an SP receptor antagonist in Neuro-Sps prior to acupuncture, we performed in vivo extracellular recording of rVLM neurons and tested the effects of Neuro-Sp injection of CP-99994 on rVLM excitability. | Brain Behav Immun. 2021 Jan;91:683-694. doi: 10.1016/j.bbi.2020.08.016. Epub 2020 Sep 18. | Cardiovascular | Mechanism |
| 32956833 | Consistent with our previous study, the present study showed that cutaneous neurogenic inflammation manifested in acupoints, such as PC6 on the wrist in IMH rats, a common treatment site for cardiac disorders or others that have been shown to be effective for cardiovascular disorders. | Brain Behav Immun. 2021 Jan;91:683-694. doi: 10.1016/j.bbi.2020.08.016. Epub 2020 Sep 18. | Cardiovascular | Mechanism |
| 32956833 | The rVLM plays an important role in regulating sympathetic activity associated with cardiovascular function and stimulation of the PC6 acupoint significantly attenuates visceral sympathoexcitatory reflex responses through activation of opioid receptors in the rVLM. | Brain Behav Immun. 2021 Jan;91:683-694. doi: 10.1016/j.bbi.2020.08.016. Epub 2020 Sep 18. | Cardiovascular | Mechanism |
| 29034548 | For example, tricyclic antidepressants result in sedation and various cardiovascular issues. | Eur J Pain. 2018 Apr;22(4):679-690. doi: 10.1002/ejp.1132. Epub 2017 Oct 16. | Cardiovascular Sedation | Mechanism |
| 31600836 | We have established that manual acupuncture (MA) at the Neiguan (P6) acupoint inhibits excitatory cardiovascular reflex responses through modulation of the autonomic nervous system in the brainstem. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular | Mechanism |
| 31600836 | We have established that manual acupuncture (MA) at the Neiguan (P6) acupoint modulates cardiovascular responses through influence on the autonomic nervous system in the brainstem. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular | Mechanism |
| 31600836 | The World Health Organization lists over 40 conditions for which acupuncture may be useful, including, among others, pain and cardiovascular diseases. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular | Mechanism |
| 31600836 | For instance, the P6 acupoint overlying median nerve is used to treat cardiovascular diseases and nausea. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular Nausea and Vomiting | Mechanism |
| 31600836 | In rodents, we have found that acupuncture applied at the Neiguan acupoint (P6) overlying the median nerve specifically modulates cardiovascular responses through influence on regions in the brainstem, including nucleus tractus solitarius, caudal and rostral ventrolateral medulla, raphe nuclei, as well as arcuate nucleus and paraventricular nucleus in the hypothalamus. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular | Mechanism |
| 31600836 | MA (~2 Hz) applied at this acupoint evokes median nerve discharge and attenuates reflex cardiovascular responses. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular | Mechanism |
| 31600836 | In previous studies, we have demonstrated that acupuncture at P6 has the specific action in modulating cardiovascular responses, compared to the insertion of acupuncture needle without stimulation as well as to acupuncture applied to other acupoints or non-acupoints in the forelimb. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular | Mechanism |
| 31600836 | Besides treating cardiovascular diseases, acupuncture at P6 is also used to manage other clinical disorders, like nausea. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular Nausea and Vomiting | Mechanism |
| 31600836 | Given the fact of involvement of the cortex in regulation of a variety of activities, including autonomic functions, the activation of these cortical areas by MA is suggestive of their participations in central processing of the action of MA at P6, particularly a potential modulation of the sympathetic outflows associated with cardiovascular system. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular | Mechanism |
| 31600836 | Notably, it contributes to cardiovascular regulation through its input and output connections to other central autonomic control regions, including the cortex, hypothalamus, and brainstem. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular | Mechanism |
| 31600836 | Previous studies have shown that its central division (Ce) is involved in modulation of cardiovascular function, likely through the mediation of the parasympathetic outflow, and its basolateral division (BL) is mainly activated in response to psychological stressors. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular | Mechanism |
| 31600836 | This nucleus is involved in central autonomic regulation, particularly, amygdala-mediated cardiovascular reactions. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular | Mechanism |
| 31600836 | Besides involvement in the metabolic regulation, the Arc has cardiovascular implications. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular | Mechanism |
| 31600836 | Our previous studies have shown that both PVN and Arc are involved in modulation of sympathoexcitaory cardiovascular reflexes by EA applied at the Jianshi (P5) and P6 acupoints. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular | Mechanism |
| 31600836 | The activated regions likely are involved directly or indirectly in the regulation of autonomic function, including cardiovascular responses. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular | Mechanism |
| 31600836 | Thus, the data from the present study provide further evidence to elucidate central neural mechanisms by which MA at P6 modulates cardiovascular responses, as we have demonstrated previously. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular | Mechanism |
| 31600836 | Our new findings advance our knowledge about neuronal activation induced by MA at P6 in the forebrain, which contributes to the organization of central neural circuits particularly involved in cardiovascular control. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular | Mechanism |
| 31600836 | Besides, future studies also will be required to confirm and validate genetic capture of acupuncture-activated specific neurons by testing its influence on the activity of neurons that control physiological function, for instance, cardiovascular function. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Cardiovascular | Mechanism |
| 30906419 | Hypertension is a substantial public health problem, affecting over 1 billion people worldwide, and results in cardiovascular diseases and chronic kidney disease. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Cardiovascular Kidney | Mechanism |
| 30906419 | To verify the microarray profiling results, four significantly expressed genes that concern cardiovascular disease, Cox5b and Sirt6 in profile 2, Nf1 and Gabbr1 in profile 7, were evaluated by qRT-PCR after gene cluster analysis. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Cardiovascular | Mechanism |
| 30906419 | The neurofibromatosis type 1 patients have an increased incidence of cardiovascular diseases, including obstructive vascular disorders and hypertension. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Cardiovascular | Mechanism |
| 30906419 | Furthermore, In vitro experiment identified a feedback loop, in which IL-33, in addition to its anti-inflammatory and protective effects in cardiovascular system, stimulates the expanding of tumorigenicity 2 (ST2)-expressing Treg during interactions with CD4+. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Cardiovascular | Mechanism |
| 34472492 | Cigarette smoking introduces nicotine into the human body and causes notable changes in physiology, leading to respiratory problems, cardiovascular disease, and chronic pain conditions. | Neural Regen Res. 2022 Apr;17(4):905-910. doi: 10.4103/1673-5374.322477. | Cardiovascular | Mechanism |
| 36636219 | People with insomnia are five times more likely to suffer from depression and anxiety than the general population, have a multiplied risk of cardiovascular disease, and have a significantly higher risk of death. | Heliyon. 2022 Dec 22;8(12):e12574. doi: 10.1016/j.heliyon.2022.e12574. eCollection 2022 Dec. | Cardiovascular Insomnia Anxiety Depression | Mechanism |
| 30872987 | Acupuncture stimulation at acupoints in the wrist, PC5-6, increased Aδ- and C-fiber activity to evoke cardiovascular effects (Zhou et al.,). | Front Neurosci. 2019 Feb 20;13:110. doi: 10.3389/fnins.2019.00110. eCollection 2019. | Cardiovascular | Mechanism |
| 30872987 | Manual and electroacupuncture at PC6-7 acupoints activate Aδ and C fibers to evoke a cardiovascular effect (Zhou et al.,), which is eliminated by neonatal capsaicin to block C-fiber afferents (Tjen-a-Looi et al.,). | Front Neurosci. 2019 Feb 20;13:110. doi: 10.3389/fnins.2019.00110. eCollection 2019. | Cardiovascular | Mechanism |
| 28806763 | It is considered as one of the highest risk factors for type 2 diabetes, cardiovascular disease, hypertension, cancer, and increased morbidity and mortality rates. | PLoS One. 2017 Aug 14;12(8):e0181948. doi: 10.1371/journal.pone.0181948. eCollection 2017. | Cardiovascular | Mechanism |
| 28806763 | However, most of the current anti-obesity drugs and therapies have failed to achieve adequate weight control in patients, due to side effects such as mood changes, suicidal thoughts, and gastrointestinal and cardiovascular complications. | PLoS One. 2017 Aug 14;12(8):e0181948. doi: 10.1371/journal.pone.0181948. eCollection 2017. | Cardiovascular Side Effects Mood | Mechanism |
| 28299842 | The pathways in which were involved the genes differentially expressed between EA-MSC and BM-MSC were analyzed using IPA®, and included cellular growth and proliferation, hepatic pathways and embryonic stem cell pluripotency, DNA damage response, axonal guidance signaling, cardiovascular system development, mitotic roles of polo-like kinase, as well as cell cycle: G2/M DNA damage checkpoint regulation, cell cycle control of chromosomal replication, GADD45 signaling and ATM signaling (Supplementary Table S5). | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Cardiovascular | Mechanism |
| 29853959 | A fMRI study found that acupuncture regulated the cardiovascular system through a neural network involving the hypothalamus, cortex, and brainstem. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Cardiovascular | Mechanism |
| 29853959 | Acupuncture stimulation of specific acupoints such as LR3 affects the cardiovascular system and accordingly may have effects on specific brain regions receiving input from somatic afferent stimulation to affect BP. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Cardiovascular Blood Pressure | Mechanism |
| 29853959 | Clinical acupuncture often involves repeated acupuncture treatments; indeed, repetitive acupuncture produces molecular changes and long-term cardiovascular effects that far outweigh the effects of one-time acupuncture stimulation. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Cardiovascular | Mechanism |
| 29853959 | Previous studies have described two possible mechanisms for the long-term cardiovascular effects of acupuncture. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Cardiovascular | Mechanism |
| 29853959 | Additionally, several medulla neurotransmitters are involved in cardiovascular regulation. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Cardiovascular | Mechanism |
| 29853959 | Furthermore, studies have shown that Ang II and oxidative stress increase neuronal activity in the paraventricular nucleus and rVLM as a mechanism maintaining sympathetic activation of the cardiovascular system in patients with renovascular hypertension. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Cardiovascular | Mechanism |
| 25206545 | Eph receptor tyrosine kinases and their membrane-bound ligands, ephrins, are involved in a variety of biological processes, such as tissue patterning, angiogenesis, and cardiovascular and skeletal development. | Neural Regen Res. 2013 Sep 5;8(25):2350-9. doi: 10.3969/j.issn.1673-5374.2013.25.006. | Cardiovascular | Mechanism |
| 25206515 | Ma et al also reported that the P2X2 and P2X4 receptors were expressed on neurons and fibers extensively distributed in the rat medulla, suggesting a binding site for the regulatory effects of adenosine triphosphate on cardiovascular activity, respiratory activity and sensation of pain. | Neural Regen Res. 2013 Aug 5;8(22):2069-77. doi: 10.3969/j.issn.1673-5374.2013.22.006. | Cardiovascular | Mechanism |
| 33062027 | According to formal research, obesity is associated with many health concerns, such as type 2 diabetes mellitus (T2DM), cardiovascular disease, and cancer. | Evid Based Complement Alternat Med. 2020 Sep 24;2020:8764507. doi: 10.1155/2020/8764507. eCollection 2020. | Cardiovascular | Mechanism |
| 33062027 | The incidence of cardiovascular events in patients with excessive waist circumference is 2.1 times that in patients with normal waist circumference. | Evid Based Complement Alternat Med. 2020 Sep 24;2020:8764507. doi: 10.1155/2020/8764507. eCollection 2020. | Cardiovascular | Mechanism |
| 33062027 | According to a report by the Organization for Economic Cooperation and Development (OECD), 70% of diabetes treatment costs, 23% of cardiovascular disease treatment costs, and 9% of cancer treatment costs are caused by obesity. | Evid Based Complement Alternat Med. 2020 Sep 24;2020:8764507. doi: 10.1155/2020/8764507. eCollection 2020. | Cardiovascular | Mechanism |
| 25206727 | Neurons in the brainstem and hypothalamus control autonomic nerve function, including cardiovascular, gastrointestinal tract, respiratory tract, urogenital and muscle-skeletal activities. | Neural Regen Res. 2013 Mar 25;8(9):802-8. doi: 10.3969/j.issn.1673-5374.2013.09.004. | Gastrointestinal Tract Cardiovascular | Mechanism |
| 37383281 | Long-term sleep disorders can easily induce immunity and memory loss, increase the risk of cardiovascular and cerebrovascular diseases, and threaten the life and health of patients. | World J Psychiatry. 2023 Jun 19;13(6):340-350. doi: 10.5498/wjp.v13.i6.340. eCollection 2023 Jun 19. | Immunity Cardiovascular | Mechanism |
| 26998388 | Trials indicate hypoglycemic, cardiovascular, antiviral, psychomotor enhancement, blood pressure normalization and asthma control properties. | J Pharmacopuncture. 2015 Dec;18(4):38-44. doi: 10.3831/KPI.2015.18.036. | Cardiovascular Blood Pressure | Mechanism |
| 27411565 | Despite their universal administration for pain relief in osteoarthritis patients, the long term use of NSAIDs is controversial due to the gastrointestinal disorders and cardiovascular events related to their safety profile. | BMC Complement Altern Med. 2016 Jul 13;16:212. doi: 10.1186/s12906-016-1204-z. | Cardiovascular Pain Relief | Mechanism |
| 34646336 | Obesity is a global epidemic disease that increases the incidence of serious diseases such as type 2 diabetes, cancer, hypertension, nonalcoholic fatty liver disease, cardiovascular diseases, and dementia. | Comput Math Methods Med. 2021 Oct 4;2021:6730274. doi: 10.1155/2021/6730274. eCollection 2021. | Cardiovascular | Mechanism |
| 34646336 | Elevated LDL is a treatable and heritable risk factor for cardiovascular disease. | Comput Math Methods Med. 2021 Oct 4;2021:6730274. doi: 10.1155/2021/6730274. eCollection 2021. | Cardiovascular | Mechanism |
| 34646336 | It is mainly manifested as a decrease in HDL, which plays an indispensable role in the development of cardiovascular diseases. | Comput Math Methods Med. 2021 Oct 4;2021:6730274. doi: 10.1155/2021/6730274. eCollection 2021. | Cardiovascular | Mechanism |
| 21799685 | Cyclooxygenase-2 inhibitors can reduce the gastrointestinal side effects, but these carry an elevated risk for cardiovascular disease, and some have now been withdrawn from the market. | Evid Based Complement Alternat Med. 2011;2011:619650. doi: 10.1093/ecam/neq016. Epub 2011 Jan 9. | Cardiovascular Side Effects | Mechanism |
| 21799685 | Another study demonstrates that EA may activate serotonin neurons in the nucleus raphe pallidus to modulate cardiovascular function. | Evid Based Complement Alternat Med. 2011;2011:619650. doi: 10.1093/ecam/neq016. Epub 2011 Jan 9. | Cardiovascular | Mechanism |
| 37179843 | Moreover, depression contributes to devastating mental trauma, brings pathophysiological disorders, and enhances susceptibility to some systematic diseases, such as cerebrovascular and cardiovascular diseases. | Neural Plast. 2023 May 2;2023:1474841. doi: 10.1155/2023/1474841. eCollection 2023. | Cardiovascular Depression | Mechanism |
| 27073385 | A distinguishing aspect of acupuncture is its ability to trigger significant modulation in different areas of the brain, in addition to changes in blood pressure and cardiovascular excitatory reflex responses (Li et al., 2010, 2012). | Neural Regen Res. 2016 Feb;11(2):305-11. doi: 10.4103/1673-5374.177740. | Cardiovascular Blood Pressure | Mechanism |
| 32547407 | PCOS is frequently associated with metabolic disorders, including obesity, abdominal adiposity, insulin resistance, alongside cardiovascular risk factors. | Front Physiol. 2020 May 29;11:474. doi: 10.3389/fphys.2020.00474. eCollection 2020. | Cardiovascular | Mechanism |
| 37384285 | Several studies have demonstrated that the stimulation of Nei-guan (PC-6), an acupoint over the wrist, is most effective in lowering blood pressure and improving cardiovascular diseases. | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Cardiovascular Blood Pressure | Mechanism |
| 37384285 | Thermal stimulation of acupoints by warm needle acupuncture has been used in the treatment of cardiovascular diseases, but the peripheral mechanism underlying the effect of warm needle acupuncture on cardiovascular diseases has not been identified. | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Cardiovascular | Mechanism |
| 37384285 | Previous studies have shown that EA stimulation increases TRPV1 activity and modulates sympathetic excitatory cardiovascular reflexes through central regulation of autonomic function. | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Cardiovascular | Mechanism |
| 37384285 | While electrical stimulation of the PC-6 acupoint can activate both A- and C-fibers of the median nerve, it has been suggested that the effects of (EA) and transcutaneous electrical nerve stimulation (TENS) on cardiovascular diseases are mediated by C-fiber activation. | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Cardiovascular | Mechanism |
| 37635258 | Seven systems: Urogenital system, Central nervous system, Respiratory system, Immune system, Cardiovascular system, Skeletal system, and Muscular system. | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Immunity Cardiovascular | Mechanism |
| 32039692 | These acupoints are prescribed most frequently for cardiac disorders or proved to be effective in cardiovascular disorders. | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Cardiovascular | Mechanism |
| 32039692 | There are several studies suggesting that the cardiovascular effects of acupuncture are due to activation of C-fibers. | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Cardiovascular | Mechanism |
| 32039692 | Furthermore, our in vivo extracellular recordings showing that stimulation at Neuro-Sps activated rVLM neurons in IMH rats, which were prevented by naloxone, suggest the involvement of endogenous opioids in neurogenic stimulation-induced changes of sympathoexcitatory cardiovascular reflexes in the rVLM. | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Cardiovascular | Mechanism |
| 32039692 | The rVLM plays an important role in regulating sympathetic outflow in the cardiovascular system. | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Cardiovascular | Mechanism |
| 32039692 | Premotor sympathetic cardiovascular neurons in the rVLM received convergent input from acupoints. | J Physiol Sci. 2020 Feb 6;70(1):14. doi: 10.1186/s12576-020-00735-4. | Cardiovascular | Mechanism |
| 35484628 | Acupuncture at Neiguan (PC6) has long been used for treating cardiovascular diseases, but its antiarrhythmic effect and the underlying mechanisms have not yet been well investigated, especially regarding premature ventricular complexes (PVCs) that occur post-myocardial infarction (MI). | Chin Med. 2022 Apr 28;17(1):52. doi: 10.1186/s13020-022-00606-7. | Cardiovascular | Mechanism |
| 35484628 | Neiguan (PC6), one of the most commonly used acupoints in cardiovascular diseases, is located in the pericardial meridian and has been confirmed to attenuate symptoms of cardiovascular disease. | Chin Med. 2022 Apr 28;17(1):52. doi: 10.1186/s13020-022-00606-7. | Cardiovascular | Mechanism |
| 29849693 | Accumulating evidence indicates that acupuncture is safe and has clinical efficacy in various disorders including cardiovascular diseases, chronic pain, functional constipation, and other pathological contexts. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Cardiovascular | Mechanism |
| 30028333 | The cardiovascular complications and the change in hemorheology after SCI are evidence of the relationship between SCI and stasis in the Governor Vessel (Berlly et al., 2007; Furlan et al., 2008). | Neural Regen Res. 2018 Jul;13(7):1241-1246. doi: 10.4103/1673-5374.235062. | Cardiovascular | Mechanism |
| 30028333 | The disturbance of the microcirculation after SCI is an important link between neurological injury, cardiovascular complications, and the change in hemodynamics after SCI (Sezer et al., 2015), which are consistent with stasis of the Governor Vessels in traditional Chinese medicine. | Neural Regen Res. 2018 Jul;13(7):1241-1246. doi: 10.4103/1673-5374.235062. | Microcirculation Cardiovascular Hemodynamics | Mechanism |
| 31275411 | Compared with general obesity, abdominal obesity is considered to be more closely associated with the risks of metabolic disease, nonalcoholic fatty liver disease, and cardiovascular diseases, which ranks as an independent risk factor of all-cause mortality. | Evid Based Complement Alternat Med. 2019 Jun 2;2019:4958294. doi: 10.1155/2019/4958294. eCollection 2019. | Cardiovascular | Mechanism |
| 25530777 | They take part in regulating many functions, like stress and cardiovascular activity. | Evid Based Complement Alternat Med. 2014;2014:179796. doi: 10.1155/2014/179796. Epub 2014 Oct 30. | Cardiovascular | Mechanism |