- The advantages of acupuncture anesthesia in clinical practice
In clinical practice, acupuncture anesthesia presents a multitude of advantages, pivotal among these being Body System Protection. This technique supports the body's natural defenses, reducing the physiological stress often associated with surgical procedures. By modulating the body's response to pain, acupuncture anesthesia allows for a lower Dosage of Medication, significantly reducing the potential for drug-related side effects. Furthermore, this approach plays a crucial role in Emotion Regulation, helping patients maintain a calm and stable emotional state, which is essential for a positive surgical outcome. The impact of acupuncture on the nervous system not only aids in Pain Relief but also promotes Enhanced Recovery After Surgery. Patients tend to experience faster recuperation times, attributed to the holistic nature of this method. Additionally, acupuncture anesthesia is associated with a Lower Incidence of Side Effects compared to conventional anesthetics. Its ability to modulate and balance the body's responses makes it an invaluable tool in the realm of modern medicine, offering a safer, more patient-centered approach to pain management and recovery.
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Modulation
- Immunity
- Acupuncture anesthesia may enhance the body's immune response, reducing the risk of postoperative infections.
- Blood Flow
- Acupuncture anesthesia can optimize blood flow to tissues, aiding in wound healing and tissue recovery.
- Endocrinology
- Acupuncture anesthesia can influence endocrine function, helping maintain hormonal balance during surgery.
- Circulation
- Acupuncture anesthesia supports overall circulatory health, ensuring adequate oxygen and nutrient delivery to tissues.
- Microcirculation
- Acupuncture anesthesia positively affects microcirculation, benefiting tissue perfusion and healing.
- Blood Pressure
- Acupuncture anesthesia can help stabilize blood pressure, reducing perioperative hypertension risks.
- Heart Rate
- Acupuncture anesthesia can regulate heart rate, promoting cardiovascular stability during surgery.
- Hemodynamics
- Acupuncture anesthesia optimizes hemodynamic parameters, contributing to surgical safety.
- Bleeding
- Acupuncture anesthesia may reduce intraoperative bleeding, enhancing surgical outcomes.
- Skin Temperature
- Acupuncture anesthesia can help maintain stable skin temperature during surgery, preventing hypothermia.
Acupuncture anesthesia for Modulation-Endocrinology
| PMID | Evidence | Source | Keyword | Type |
|---|---|---|---|---|
| 15320437 | The first system belongs to the neuro-endocrine system which forms painful reactions, the second one is connected with ""alive matrix""--uniform system of the connective tissue which connects an environment through acupuncture points with intercellular space, and also with intracellular structures of each cell. | Fiziol Zh (1994). 2004;50(3):92-102. | Endocrinology | Review |
| 17264833 | The present paper briefly discusses clinical and experimental data on the effect of acupuncture on uterine and ovarian blood flow, as an analgesic method during ART, and on endocrine and metabolic disturbances such as polycystic ovary syndrome (PCOS). | Acupunct Med. 2006 Dec;24(4):157-63. doi: 10.1136/aim.24.4.157. | Endocrinology Blood Flow | Review |
| 17663116 | The present paper reviews the studies on nervous regulation, humoral regulation and regulation of peripheral vessel resistance and other pathways and their relationships in recent ten years, and indicates further perfecting these studies from the following aspects: studies on the mechanism of section and combination of blood pressure-decreasing points, relationship of time-effect and dose-effect of acupuncture and moxibustion, and studies on mechanisms of functions of nerve-endocrine-immune system. | Zhongguo Zhen Jiu. 2007 Jun;27(6):467-70. | Immunity Endocrinology Blood Pressure | Review |
| 18047551 | Clearly, acupuncture can affect PCOS via modulation of endogenous regulatory systems, including the sympathetic nervous system, the endocrine and the neuroendocrine system. | J Neuroendocrinol. 2008 Mar;20(3):290-8. doi: 10.1111/j.1365-2826.2007.01634.x. Epub 2007 Nov 28. | Endocrinology | Review |
| 18047551 | Experimental observations in rat models of steroid-induced polycystic ovaries and clinical data from studies in women with PCOS suggest that acupuncture exert long-lasting beneficial effects on metabolic and endocrine systems and ovulation. | J Neuroendocrinol. 2008 Mar;20(3):290-8. doi: 10.1111/j.1365-2826.2007.01634.x. Epub 2007 Nov 28. | Endocrinology | Review |
| 18688727 | Current technology suggests that acupuncture modulates neurological processes within the central nervous system, especially the spinal cord gating mechanisms, cerebral subcortical nuclei, and the hypothalamic-endocrine axis. | Curr Treat Options Oncol. 2008 Jun;9(2-3):117-26. doi: 10.1007/s11864-008-0063-3. Epub 2008 Aug 8. | Endocrinology | Review |
| 18807728 | In the present paper, the authors review the progress in acupuncture treatment of hypertension in recent ten years from the studies of clinical treatment and animal experiments; analyze the underlying mechanism of acupuncture in protecting target organs of hypertension from the neuro-endocrine-immune network. | Zhen Ci Yan Jiu. 2008 Jun;33(3):208-12. | Immunity Endocrinology | Review |
| 19063831 | Since the effects of acupuncture change with women's endocrine cycles, it is important and possible to make a breakthrough in ART outcomes if acupuncture is performed at a suitable time point during the cycle of IVF/ET combined with ART. | Zhong Xi Yi Jie He Xue Bao. 2008 Dec;6(12):1211-6. doi: 10.3736/jcim20081201. | Endocrinology | Review |
| 19761120 | The authors of the present paper review researches on the underlying mechanism of joint application of acupuncture therapy and medication in recent decade from (1) neural regulation, (2) endocrine regulation, and (3) immunological regulation. | Zhen Ci Yan Jiu. 2009 Jun;34(3):212-6. | Immunity Endocrinology | Review |
| 20204371 | Furthermore, greatly enhanced life quality of RA patients was obtained using acupuncture and massage to relieve pain, expand joint motion and modulate emotion which mainly correlated with the possible modulation of immune system, nerve system, endocrine system, etc. | Rheumatol Int. 2010 Apr;30(6):713-8. doi: 10.1007/s00296-010-1370-0. Epub 2010 Mar 5. | Immunity Endocrinology Mood | Review |
| 20209980 | There are also several lines of evidence suggesting that the acupuncture effects involve complex mechanisms at multiple levels, including intracellular signal transduction, gene expression, endocrine secretion, humoral and dielectric regulation. | Zhen Ci Yan Jiu. 2009 Dec;34(6):413-20. | Endocrinology | Review |
| 21611904 | Firstly, acupuncture may improve ovulation by modulating the central and peripheral nervous systems, the neuroendocrine and endocrine systems, the ovarian blood flow, and metabolism. | Chin J Integr Med. 2011 May;17(5):386-95. doi: 10.1007/s11655-011-0611-8. Epub 2011 May 25. | Endocrinology Blood Flow | Review |
| 21617789 | Therefore standard painkillers, NSAIDs (COX2 inhibitors), week opioids and other interventions (vitamin D, calcium, bisphosphonates, exercise, acupuncture, complementary and alternative approaches, eventually switch to another endocrine drug) are used for managing this treatment-related side effect, and improve adherence and quality of life among breast cancer survivors. | Magy Onkol. 2011 Mar;55(1):32-9. Epub 2011 Mar 31. | Endocrinology Side Effects | Review |
| 23072106 | And the result shows that the two-way regulatory effect of acupuncture on gastrointestinal motility function which eventually causes the recovery of gastrointestinal function, is a benign regulation reached by relative antagonism and inter-coordination of the neural, endocrine and immunity in all aspects. | Zhongguo Zhen Jiu. 2012 Aug;32(8):765-8. | Immunity Endocrinology | Review |
| 23416841 | Clinical and experimental evidence indicates that acupuncture may be a safe alternative or complement in the treatment of endocrine and reproductive function in women with polycystic ovary syndrome (PCOS). | Mol Cell Endocrinol. 2013 Jul 5;373(1-2):83-90. doi: 10.1016/j.mce.2013.01.006. Epub 2013 Feb 14. | Endocrinology | Review |
| 24106314 | Acupuncture modulates the neuro-endocrine-immune network. | QJM. 2014 May;107(5):341-5. doi: 10.1093/qjmed/hct196. Epub 2013 Oct 8. | Immunity Endocrinology | Review |
| 2678566 | It has been shown that stimulation by acupuncture, mechanically or electrically, stimulates certain endocrine control mechanisms, which cause the release of morphine like substances. | Ther Umsch. 1989 Aug;46(8):518-25. | Endocrinology | Review |
| 2678566 | These endocrine controls are not only stimulated by acupuncture, but also are activated by other pain fighting techniques that utilize peripheral stimulation. | Ther Umsch. 1989 Aug;46(8):518-25. | Endocrinology | Review |
| 28078850 | Acupuncture in endocrine disorders: a critical appraisal. | J Biol Regul Homeost Agents. 2016 Oct-Dec;30(4):1035-1040. | Endocrinology | Review |
| 28078850 | Acupuncture has been tried extensively in the management of various endocrine disorders with inconsistent results. | J Biol Regul Homeost Agents. 2016 Oct-Dec;30(4):1035-1040. | Endocrinology | Review |
| 28078850 | In this review, we highlight the principles of acupuncture and its role in the management of various endocrine disorders. | J Biol Regul Homeost Agents. 2016 Oct-Dec;30(4):1035-1040. | Endocrinology | Review |
| 29393105 | We find that, in these hypertensive animals, acupuncture could mainly influence factors related to the nervous system, oxidative stress, the endocrine system, cardiovascular function, and hemorheology, which are closely associated with the stroke outcome. | Complement Med Res. 2018;25(1):45-51. doi: 10.1159/000475930. Epub 2018 Jan 23. | Cardiovascular Endocrinology | Review |
| 29888561 | From the perspective of the cutaneous and systemic neuro-immuno-endocrine networks, it undoubtedly prompts us to profoundly explore the underlying biological mechanisms of acupuncture. | Zhen Ci Yan Jiu. 2018 May 25;43(5):285-9. doi: 10.13702/j.1000-0607.170911. | Immunity Endocrinology | Review |
| 29940063 | It includes a description of how acupuncture is thought to work and what the intervention entails, data on acupuncture for managing pain caused by cancer or by cancer treatment (radiation, chemotherapy, endocrine therapy), how acupuncture is practiced in the US medical system, discussion of safety issues, and practical tips on how to integrate acupuncture into cancer care. | Oncology (Williston Park). 2018 Jun;32(6):310-6. | Endocrinology | Review |
| 30157368 | The present paper summarizes the literature from domestic and international databases about acupuncture treatment of oligoasthenozoospermia, and offers an overview of the effects of acupuncture on the reproductive endocrine system, testicular blood flow, semen quality, and rate of conception in the treatment of the patient. | Zhonghua Nan Ke Xue. 2018 Janurary;24(1):86-90. | Endocrinology Blood Flow | Review |
| 30707414 | Lines of evidence have pointed out that the regulation of neuro-endocrine-immune networks may be a common switch of acupuncture on different nerve system diseases. | Chin J Integr Med. 2020 Apr;26(4):310-320. doi: 10.1007/s11655-019-3150-3. Epub 2019 Feb 1. | Immunity Endocrinology | Review |
| 31344252 | The mechanism behind acupuncture's effects on the body and brain has not been completely elucidated, but there is evidence that acupuncture has effects on the endocrine, immune, and sympathetic and parasympathetic nervous systems. | Obstet Gynecol Surv. 2019 Apr;74(4):241-251. doi: 10.1097/OGX.0000000000000655. | Immunity Endocrinology | Review |
| 32186125 | Mechanism of electroacupuncture on inflammatory pain: neural-immune-endocrine interactions. | J Tradit Chin Med. 2019 Oct;39(5):740-749. | Immunity Endocrinology Inflammatory Pain | Review |
| 32186125 | Furthermore, the hypothalamic-pituitary-adrenal axis, sympathetic and vagal nervous may serve as an essential pathway involved in the mechanism of acupuncture-mediated analgesia within the interactions of the central, immune and endocrine systems. | J Tradit Chin Med. 2019 Oct;39(5):740-749. | Immunity Endocrinology | Review |
| 33371816 | The number of clinical publications concerning acupuncture-treated neurological diseases, endocrine and metabolic diseases, circulatory diseases, respiratory diseases, etc. | Am J Chin Med. 2021;49(1):1-23. doi: 10.1142/S0192415X21500014. Epub 2020 Dec 26. | Endocrinology Circulation | Review |
| 33992269 | While the theoretical constructs underlying the use of acupuncture and dry needling are unique, both appear to have the ability to elicit biochemical, biomechanical, endocrinological and neurovascular changes associated with reductions in pain and disability. | J Bodyw Mov Ther. 2021 Apr;26:353-363. doi: 10.1016/j.jbmt.2020.12.003. Epub 2020 Dec 3. | Endocrinology | Review |
| 35880284 | Moreover, the evidences of acupuncture may be obtained for its clinical treatment of DOR and other reproductive endocrine diseases. | Zhen Ci Yan Jiu. 2022 Jul 25;47(7):644-8. doi: 10.13702/j.1000-0607.20210330. | Endocrinology | Review |
| 37406378 | The acupuncture regulatory network consists of three main components: the acupoint network, the neuro-endocrine-immune (NEI) network, and the disease network. | Pathol Res Pract. 2023 Aug;248:154652. doi: 10.1016/j.prp.2023.154652. Epub 2023 Jun 26. | Immunity Endocrinology | Review |
| 37598978 | Acupuncture is effective intervention, particularly in nerve, endocrine diseases and immune diseases. | Life Sci. 2023 Oct 15;331:122031. doi: 10.1016/j.lfs.2023.122031. Epub 2023 Aug 19. | Immunity Endocrinology | Review |
| 24073009 | This review addresses acupuncture as a potential treatment option for reproductive and endocrine disturbances in women with PCOS. | Evid Based Complement Alternat Med. 2013;2013:762615. doi: 10.1155/2013/762615. Epub 2013 Sep 2. | Endocrinology | Review |
| 24278807 | Practitioners should consider scalp acupuncture as either the primary approach or a complementary approach when treating disorders of the central nervous system and endocrine system. | Glob Adv Health Med. 2012 Mar;1(1):102-21. doi: 10.7453/gahmj.2012.1.1.017. | Endocrinology | Review |
| 24716183 | In the last half of the 20th century, many studies conducted in animals and humans have demonstrated multiple biological responses related to acupuncture, including (a) neural regulation, (b) endocrine regulation, and (c) immunological regulation. | J Tradit Complement Med. 2013 Oct;3(4):234-9. doi: 10.4103/2225-4110.119733. | Immunity Endocrinology | Review |
| 24723957 | For its part, according to Western medicine, therapeutic mechanisms of acupuncture are unclear, but some evidence suggests that acupuncture can affect the intrarenal renin-angiotensin system and sympathetic nervous and endocrine systems. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Endocrinology | Review |
| 24723957 | Acupuncture may also affect the endocrine system and lead to a decrease in plasma renin, aldosterone, angiotensin II, norepinephrine, and serotonin. | Evid Based Complement Alternat Med. 2014;2014:279478. doi: 10.1155/2014/279478. Epub 2014 Mar 4. | Endocrinology | Review |
| 26823672 | Asamoto and Takeshige (1992) stimulated the rat inner auricular areas that represent the human pylorus, lung, trachea, stomach, esophagus, and endocrine, and heart acupuncture points induced the action potentials in the hypothalamic ventromedial nucleus (HVM), the satiety center. | Evid Based Complement Alternat Med. 2015;2015:495684. doi: 10.1155/2015/495684. Epub 2015 Dec 28. | Endocrinology | Review |
| 27217981 | There is an abundance of evidence that acupuncture modulates a wide range of endocrinological, neurohormonal, immunological, paracrine and autocrine factors. | Curr Obstet Gynecol Rep. 2016;5:110-118. doi: 10.1007/s13669-016-0156-0. Epub 2016 Apr 25. | Immunity Endocrinology | Review |
| 30117343 | Acupuncture can help reduce unpleasant side effects associated with endocrine therapy for breast cancer. | Integr Cancer Ther. 2018 Sep;17(3):602-618. doi: 10.1177/1534735418786801. | Endocrinology Side Effects | Review |
| 30416533 | Also, acupuncture has been proven to be an effective treatment for reducing stress, anxiety, and depression via modulation of brain stress and endocrine systems in preclinical and clinical studies. | Evid Based Complement Alternat Med. 2018 Oct 17;2018:5367864. doi: 10.1155/2018/5367864. eCollection 2018. | Endocrinology Anxiety Depression | Review |
| 30416533 | Acupuncture also has proven to be an effective treatment for reducing stress, anxiety, and depression via modulation of brain stress and endocrine systems in clinical studies. | Evid Based Complement Alternat Med. 2018 Oct 17;2018:5367864. doi: 10.1155/2018/5367864. eCollection 2018. | Endocrinology Anxiety Depression | Review |
| 30854010 | Clinical studies suggested that acupuncture regulates endocrine system, promotes digestion, attenuates oxidative stress, and modulates relevant molecules of metabolism in patients of simple obesity. | Evid Based Complement Alternat Med. 2019 Feb 3;2019:5796381. doi: 10.1155/2019/5796381. eCollection 2019. | Endocrinology | Review |
| 30854010 | Acupuncture Regulated Endocrine System in Patients of Simple Obesity | Evid Based Complement Alternat Med. 2019 Feb 3;2019:5796381. doi: 10.1155/2019/5796381. eCollection 2019. | Endocrinology | Review |
| 30854010 | A study based on 64 obese adult patients illustrated the relationship between the level of plasma nesfatin-1 and the metabolic and anthropometric parameters in obese adults and the features of the regulatory mechanism of acupuncture about endocrine system. | Evid Based Complement Alternat Med. 2019 Feb 3;2019:5796381. doi: 10.1155/2019/5796381. eCollection 2019. | Endocrinology | Review |
| 30854010 | Acupuncture also activated other endocrine-related cytokines such as insulin and epinephrine (Ad) but further studies are needed to confirm its role in the pathophysiology of simple obesity. | Evid Based Complement Alternat Med. 2019 Feb 3;2019:5796381. doi: 10.1155/2019/5796381. eCollection 2019. | Endocrinology | Review |
| 30854010 | It is demonstrated that acupuncture applied at specific acupoints can contribute to the restoration of endocrine and metabolic disorders in subjects with simple obesity. | Evid Based Complement Alternat Med. 2019 Feb 3;2019:5796381. doi: 10.1155/2019/5796381. eCollection 2019. | Endocrinology | Review |
| 30854010 | Based on findings to date, clinical studies about the mechanisms of acupuncture on simple obesity mainly focused on regulating endocrine system, promoting digestion and modulating relevant molecules of metabolism, while evidence from laboratory indicated that acupuncture regulates lipid metabolism, attenuates oxidative stress, modulates inflammatory responses and promotes white adipose tissue browning. | Evid Based Complement Alternat Med. 2019 Feb 3;2019:5796381. doi: 10.1155/2019/5796381. eCollection 2019. | Endocrinology | Review |
| 30915143 | More and more researches have shown that acupuncture is a kind of nociceptive stimulus, which can cause inflammatory reaction in the sites of acupuncture and then further activate the nerve-endocrine-immune systems to cause the cascade amplification of the acupuncture effect. | Evid Based Complement Alternat Med. 2019 Feb 24;2019:2326867. doi: 10.1155/2019/2326867. eCollection 2019. | Immunity Endocrinology | Review |
| 30915143 | The information of acupuncture is amplified by cascade, and the nerve endocrine immune system (NEI) is activated through the large network of meridians (Meridian Network) of the body itself. | Evid Based Complement Alternat Med. 2019 Feb 24;2019:2326867. doi: 10.1155/2019/2326867. eCollection 2019. | Immunity Endocrinology | Review |
| 30915143 | The nerve-endocrine-immune system (NEI) further outputs the effect information to the target organ through multilevel and multisystems and finally acts on the disease network (Disease Network) to produce acupuncture effect. | Evid Based Complement Alternat Med. 2019 Feb 24;2019:2326867. doi: 10.1155/2019/2326867. eCollection 2019. | Immunity Endocrinology | Review |
| 30915143 | The information of acupuncture is amplified by cascade, and the nerve endocrine immune system (NEI) is activated through the large network of meridians (Meridian Network) of the body itself. | Evid Based Complement Alternat Med. 2019 Feb 24;2019:2326867. doi: 10.1155/2019/2326867. eCollection 2019. | Immunity Endocrinology | Review |
| 30915143 | The nerve-endocrine-immune system (NEI) further outputs the effect information to the target organ through multilevel and multisystems and finally acts on the disease network (Disease Network) to produce acupuncture effect. | Evid Based Complement Alternat Med. 2019 Feb 24;2019:2326867. doi: 10.1155/2019/2326867. eCollection 2019. | Immunity Endocrinology | Review |
| 30915143 | It is believed that acupuncture can cause specific response changes in the local microenvironment of acupoints, involving many aspects like divine meridian, endocrine, immunity, and so on. | Evid Based Complement Alternat Med. 2019 Feb 24;2019:2326867. doi: 10.1155/2019/2326867. eCollection 2019. | Immunity Endocrinology | Review |
| 30915143 | Depending on the pituitary, hypothalamic-pituitary-adrenal axis, hypothalamic-pituitary-thyroid axis, and hypothalamic-pituitary-gonadal axis, the relationship is mainly manifested in the release of endocrine hormones after acupuncture. | Evid Based Complement Alternat Med. 2019 Feb 24;2019:2326867. doi: 10.1155/2019/2326867. eCollection 2019. | Endocrinology | Review |
| 30915143 | As one of the initial factors of acupuncture effect, the inflammatory reaction further activates the nerve-endocrine-immune network to cause the cascade amplification of the acupuncture effect. | Evid Based Complement Alternat Med. 2019 Feb 24;2019:2326867. doi: 10.1155/2019/2326867. eCollection 2019. | Immunity Endocrinology | Review |
| 30984420 | Therefore, the mechanism of acupuncture's beneficial effects is related to the sympathetic outflow and regulation of the endocrine system. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Endocrinology | Review |
| 31223326 | Based on the available evidence, NTCT including acupuncture, Qigong, and Tai Chi was found to possibly improve brain metabolites, brain activity, and immune and endocrine systems in patients with major depressive disorder. | Evid Based Complement Alternat Med. 2019 May 15;2019:2183403. doi: 10.1155/2019/2183403. eCollection 2019. | Immunity Endocrinology | Review |
| 31467579 | Although many studies have shown that neuroimmune-endocrine networks, nerve nuclei, neurotransmitters, body fluids, and gastrointestinal hormones are all involved in the beneficial effects of acupuncture in regulating gastrointestinal functions, the mechanism of electroacupuncture regulating the gastrointestinal functions is rarely seen from the perspective of MAPK signal transduction regulation. | Evid Based Complement Alternat Med. 2019 Jul 31;2019:8138017. doi: 10.1155/2019/8138017. eCollection 2019. | Endocrinology | Review |
| 33133214 | Additionally, ear acupuncture was performed at the following points: Sanjiao, Jidian (hunger), Wei (stomach), Shenmen, Neifenmi (endocrine), and Pi (spleen). | Evid Based Complement Alternat Med. 2020 Oct 9;2020:3285363. doi: 10.1155/2020/3285363. eCollection 2020. | Endocrinology | Review |
| 33936242 | Research has shown that acupuncture can regulate the hypothalamic-pituitary-ovarian axis (HPOA) function by activating the dopamine system in the brain, adjusting the function of HPOA so as to restore the dynamic balance of reproductive endocrine system back to normal physiology. | Evid Based Complement Alternat Med. 2021 Apr 15;2021:6677767. doi: 10.1155/2021/6677767. eCollection 2021. | Endocrinology | Review |
| 34055020 | Both abdominal acupuncture and metformin can improve the endocrine and metabolic functions of obese PCOS patients. | Evid Based Complement Alternat Med. 2021 May 17;2021:6678398. doi: 10.1155/2021/6678398. eCollection 2021. | Endocrinology | Review |
| 34055020 | It has been found that acupuncture and moxibustion could regulate the reproductive and endocrine function of PCOS patients by affecting various signal pathways and targets of hypothalamus pituitary gonadal axis. | Evid Based Complement Alternat Med. 2021 May 17;2021:6678398. doi: 10.1155/2021/6678398. eCollection 2021. | Endocrinology | Review |
| 34055020 | Studies have shown that acupuncture can regulate endogenous regulatory systems, including endocrine, sympathetic nervous system, and neuroendocrine system, thereby improving women's endocrine disorders, menstrual frequency, and reducing the level of sex hormones. | Evid Based Complement Alternat Med. 2021 May 17;2021:6678398. doi: 10.1155/2021/6678398. eCollection 2021. | Endocrinology | Review |
| 34055020 | Furthermore, acupuncture has a significant effect on reducing body mass index of PCOS women, and it can also activate the physiological process similar to physical exercise to reduce obesity, so as to improve the physical quality and endocrine environment of PCOS patients and regulate the menstrual cycle. | Evid Based Complement Alternat Med. 2021 May 17;2021:6678398. doi: 10.1155/2021/6678398. eCollection 2021. | Endocrinology | Review |
| 34055020 | In general, regulating the reproductive and endocrine disorders of PCOS from the perspective of vagus nerve, introducing at-VNS into the treatment of PCOS, and improving acupuncture therapy such as ear acupuncture may become the new research directions. | Evid Based Complement Alternat Med. 2021 May 17;2021:6678398. doi: 10.1155/2021/6678398. eCollection 2021. | Endocrinology | Review |
| 34178633 | As a complementary and alternative medicine, the mechanism of action of acupuncture is not clear, but it is thought to be useful in improving complications such as lymphedema and upper extremity impairment caused by modified radical mastectomy, hot flashes and arthralgias related to endocrine therapy, cancer-related fatigue, chemotherapy-related peripheral neuropathy and the QoL, with less adverse effects. | Front Oncol. 2021 Jun 10;11:646315. doi: 10.3389/fonc.2021.646315. eCollection 2021. | Endocrinology Adverse Reactions | Review |
| 34281592 | Evidence has shown that acupuncture has anti-inflammatory actions that affect multiple body systems, including the immune, locomotory, endocrine, nervous, digestive, and respiratory systems, by downregulating pro-inflammatory M1 and upregulating anti-inflammatory M2 macrophages, as well as by modulating associated cytokine secretion. | Chin Med. 2021 Jul 19;16(1):56. doi: 10.1186/s13020-021-00466-7. | Immunity Gastrointestinal Tract Endocrinology | Review |
| 34281592 | Here, we summarize the potential pathways of acupuncture modulation of macrophage polarization via nervous, endocrine and immune regulation. | Chin Med. 2021 Jul 19;16(1):56. doi: 10.1186/s13020-021-00466-7. | Immunity Endocrinology | Review |
| 34281592 | Therefore, we speculate that modulation of the nervous-endocrine-immune system leading to the induction of macrophage polarization is an explanation for the effects of acupuncture. | Chin Med. 2021 Jul 19;16(1):56. doi: 10.1186/s13020-021-00466-7. | Immunity Endocrinology | Review |
| 34281592 | Nevertheless, there are still many unsolved issues, for instance, the relationship between acupuncture, the neural-endocrine-immune network, and the upstream mechanisms of macrophage polarization which are worthy of further study. | Chin Med. 2021 Jul 19;16(1):56. doi: 10.1186/s13020-021-00466-7. | Immunity Endocrinology | Review |
| 34437474 | Research Progress on the Mechanism of the Acupuncture Regulating Neuro-Endocrine-Immune Network System | Vet Sci. 2021 Jul 30;8(8):149. doi: 10.3390/vetsci8080149. | Immunity Endocrinology | Review |
| 34437474 | Since the theory of the neuro-endocrine-immune network was put forward, new insights have been brought into the understanding of the mechanism of acupuncture. | Vet Sci. 2021 Jul 30;8(8):149. doi: 10.3390/vetsci8080149. | Immunity Endocrinology | Review |
| 34437474 | This review summarizes the research progress on the neuro-endocrine-immune network related mechanism of acupuncture and discusses its current challenges and future directions. | Vet Sci. 2021 Jul 30;8(8):149. doi: 10.3390/vetsci8080149. | Immunity Endocrinology | Review |
| 34437474 | Clinical observations and primary research have indicated that the adjustment of Zang-Fu by acupuncture depends on the neuro-endocrine-immune network to a large extent. | Vet Sci. 2021 Jul 30;8(8):149. doi: 10.3390/vetsci8080149. | Immunity Endocrinology | Review |
| 34437474 | Mechanisms of Acupuncture on the Neuro-Endocrine-Immune Network | Vet Sci. 2021 Jul 30;8(8):149. doi: 10.3390/vetsci8080149. | Immunity Endocrinology | Review |
| 34437474 | Effects of Acupuncture on the Endocrine System | Vet Sci. 2021 Jul 30;8(8):149. doi: 10.3390/vetsci8080149. | Endocrinology | Review |
| 34437474 | In this section, the hypothalamic-pituitary-thyroid axis (HPT axis) has been selected as an example, introducing the regulating effect of acupuncture on the endocrine system. | Vet Sci. 2021 Jul 30;8(8):149. doi: 10.3390/vetsci8080149. | Endocrinology | Review |
| 34437474 | Meanwhile, the effects of acupuncture on the interaction between various cells and cytokines under the neuro-endocrine-immune system are also unclear. | Vet Sci. 2021 Jul 30;8(8):149. doi: 10.3390/vetsci8080149. | Immunity Endocrinology | Review |
| 34437474 | Therefore, the combination of the evolving omics technology and the emerging analysis methods of biological information may facilitate the study of acupuncture and enable the mechanism of acupuncture on the neuro-endocrine-immune network to be revealed intensively. | Vet Sci. 2021 Jul 30;8(8):149. doi: 10.3390/vetsci8080149. | Immunity Endocrinology | Review |
| 34616477 | This finding suggests that acupuncture may play a potential role in restoring reproductive endocrine function in PCOS-like animal models. | Evid Based Complement Alternat Med. 2021 Sep 24;2021:5595478. doi: 10.1155/2021/5595478. eCollection 2021. | Endocrinology | Review |
| 34675729 | Given its non-pharmacological basis, acupuncture also obviates the concerns with respect to toxicity and AEs that commonly occur when using hypnotics/sedatives, such as hangover, tolerance, increased alertness, and even endocrinological, hematological or cardiovascular events, and concerns regarding common side effects of contemporary antidepressive agents, such as dry mouth, cardiovascular/gastrointestinal side effects, seizure, bleeding, sexual dysfunction, weight gain, and even suicidality. | Nat Sci Sleep. 2021 Oct 12;13:1823-1863. doi: 10.2147/NSS.S332474. eCollection 2021. | Cardiovascular Endocrinology Toxic Side Effects Side Effects Bleeding | Review |
| 34992414 | This study comprehensively reviews and presents literature from the last five years, showing that acupuncture indeed exerts strong anti-inflammatory effects in multiple biological systems, namely, the immune, digestive, respiratory, nervous, locomotory, circulatory, endocrine, and genitourinary systems. | J Inflamm Res. 2021 Dec 21;14:7191-7224. doi: 10.2147/JIR.S341581. eCollection 2021. | Immunity Gastrointestinal Tract Endocrinology Circulation | Review |
| 34992414 | Taken together, in cases of endocrine diseases such as diabetes, obesity, and diabetic complications, ST36 is the most frequently used acupuncture point. | J Inflamm Res. 2021 Dec 21;14:7191-7224. doi: 10.2147/JIR.S341581. eCollection 2021. | Endocrinology | Review |
| 35360658 | However, the mechanism underpinning the clinical effectiveness of acupuncture in UC patients is still not completely understood, although proposed mechanisms include modulation of gastrointestinal motility, visceral sensitivity, the neuro-endocrine-immune axis, inflammation, and the brain-gut axis. | Evid Based Complement Alternat Med. 2022 Mar 22;2022:8362892. doi: 10.1155/2022/8362892. eCollection 2022. | Immunity Endocrinology | Review |
| 35782337 | In addition, new evidence also suggests that NAFLD is closely related to intestinal flora, and acupuncture has been proved to be involved in the treatment of various diseases, including nervous system diseases, endocrine diseases, and digestive system diseases, by regulating intestinal flora. | Gastroenterol Res Pract. 2022 Jun 22;2022:5259088. doi: 10.1155/2022/5259088. eCollection 2022. | Gastrointestinal Tract Endocrinology | Review |
| 36353235 | The use of acupuncture in the reproductive endocrinology and infertility of PCOS has recently gained increased popularity worldwide. | Front Endocrinol (Lausanne). 2022 Oct 24;13:1035929. doi: 10.3389/fendo.2022.1035929. eCollection 2022. | Endocrinology | Review |
| 36353235 | Evidence has shown that acupuncture elevates the level of β-endorphin not only in the central endocrine system but also in the peripheral circulation, which is associated with both direct and indirect tonic inhibitions of GnRH and subsequent LH release. | Front Endocrinol (Lausanne). 2022 Oct 24;13:1035929. doi: 10.3389/fendo.2022.1035929. eCollection 2022. | Endocrinology Circulation | Review |
| 36698826 | Although the mechanism underlying acupuncture-induced analgesia is not clear, it has been shown to exert its analgesic effects though nervous system modulation, endocrine regulation, and smooth muscle relaxation on visceral pain. | Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. | Analgesic Effect Visceral Pain Endocrinology | Review |
| 36852393 | Available studies have indicated that acupuncture treats PD by regulating endocrine and analgesic substances, modulating immune-inflammatory responses, improving uterine blood flow, and reducing oxidative stress. | Pain Res Manag. 2023 Feb 18;2023:8307249. doi: 10.1155/2023/8307249. eCollection 2023. | Immunity Endocrinology Blood Flow | Review |
| 36968499 | In regard to the period from 2006 to 2010, the primary foci of the research were: (1) barostat testing, nutrient drink test, water load test, stool antigen test, 13C-octanoic acid breath test, gastric emptying scintigraphy, intraluminal electrical impedance, and electrogastrography; (2) H. pylori infection; (3) BMI and smoking; (4) GERD, hiatal hernia, atrophic gastritis, intestinal metaplasia, gastric adenocarcinoma, and duodenal ulcer; (5) duodenogastric reflux; (6) dysrhythmia; (7) gastric fundus tone, antroduodenal motility, impaired gastric accommodation, slow gastric emptying, and gastric acid secretion; (8) visceral hypersensitivity and visceral perception; (9) type 2 diabetes mellitus, insulin resistance, and impaired glucose tolerance; (10) metabolic syndrome; (11) chest pain, nausea, constipation, epigastric pain, heartburn, and gastric distension; (12) psychological factor, abuse history, and stress; (13) triple therapy, metronidazole, PPIs, baclofen, alosetron, atropine, prokinetic agent, serotonin reuptake inhibitor, psychotherapy, and nonsteroidal anti-inflammatory drug; (14) Mentha à piperita L., Glycyrrhiza glabra, Iberis amara, Matricaria recutita, Carum carvi, Chamomilla recutita, Chelidonium majus, caraway oil, Silybum marianum, Angelica archangelica, and STW5; (15) electrical stimulation and acupuncture; (16) diabetic gastroparesis and autonomic neuropathy; (17) stress, anxiety, and depression; (18) endocrine cell; (19) melatonin, leptin, 5-hydroxytryptamine (serotonin), and ghrelin; (20) cholecystokinin A receptor; (21) gut microbiota; (22) dietary fiber, gluten, high fat meal, lipid metabolism, and carbohydrate metabolism; (23) duodenal eosinophilia and oxidative stress; (24) antioxidant, arginine, nitric oxide, and glutathione; and (25) CagA and vacuolating cytotoxin. | Front Neurosci. 2023 Mar 8;17:1109510. doi: 10.3389/fnins.2023.1109510. eCollection 2023. | Endocrinology Nausea and Vomiting Anxiety Depression | Review |
| 37025378 | According to existing studies, acupuncture can treat diseases by conducting information exchange between immune-neuro-endocrine-microbial metabolism through brain-intestinal interaction. | Front Neurosci. 2023 Mar 21;17:1146946. doi: 10.3389/fnins.2023.1146946. eCollection 2023. | Immunity Endocrinology | Review |
| 37051548 | One study found that acupuncture might alleviate fatigue by influencing neuter regulation, endocrine regulation, immune regulation, rhythm regulation, and other aspects of cancer fatigue. | Front Oncol. 2023 Mar 27;13:1071326. doi: 10.3389/fonc.2023.1071326. eCollection 2023. | Immunity Endocrinology | Review |
| 37260441 | This article reviews the efficacy and safety of Chinese herbs and other TCM (such as acupuncture) in the treatment of PCOS and its complications in recent years, as well as the effect and mechanism on cellular endocrine, in order to provide a new clinical idea for the treatment of PCOS. | Front Endocrinol (Lausanne). 2023 May 16;14:956772. doi: 10.3389/fendo.2023.956772. eCollection 2023. | Endocrinology | Review |
| 37260441 | In addition, acupuncture can improve vascular endothelial function, regulate dyslipidemia, correct IR, and improve endocrine disorders. | Front Endocrinol (Lausanne). 2023 May 16;14:956772. doi: 10.3389/fendo.2023.956772. eCollection 2023. | Endocrinology | Review |
| 37260441 | The therapeutic effect is superior to that of Western medicine alone, and there are no adverse reactions, based on the research of Jo J et al.. Acupuncture combined with TCM could improve the endocrine level and IR of phlegm-dampness PCOS and reduce miR-29 expression and TCM symptom score. | Front Endocrinol (Lausanne). 2023 May 16;14:956772. doi: 10.3389/fendo.2023.956772. eCollection 2023. | Endocrinology Adverse Reactions | Review |
| 37405111 | Diverse studies on the use of low frequency electroacupuncture (EA), alone or in combination with Western medicine or with exercise to modulate the sympathetic nervous system, reveal that acupuncture regulates the hypersecretion of androgens improving both reproductive and endocrine metabolic functional states. | J Pharmacopuncture. 2023 Jun 30;26(2):105-123. doi: 10.3831/KPI.2023.26.2.105. | Endocrinology | Review |
| 37405111 | We also included information from the main databases for randomized (RCT) and non-randomized controlled trials (non-RCT) and attested to acupuncture efficacy in resolving the main symptoms of PCOS regarding endocrine, metabolic, and emotional features. | J Pharmacopuncture. 2023 Jun 30;26(2):105-123. doi: 10.3831/KPI.2023.26.2.105. | Endocrinology Mood | Review |
| 37405111 | Laser intervention related to a healthy lifestyle (study 4), manual and electroacupuncture alone (group C of study 3, and study 5) and linked to WM intervention such as clomiphene intake (group A of study 3) were the interventions explored to recognize the impact on the metabolic and endocrine features of the syndrome in these studies. | J Pharmacopuncture. 2023 Jun 30;26(2):105-123. doi: 10.3831/KPI.2023.26.2.105. | Endocrinology | Review |
| 37405111 | According to the reviewed literature, with respect to endocrine outcomes addressing the treatment of ovarian dysfunction present in women with PCOS, we identified that a higher success for acupuncture was related to: 1) a higher number of treatment sessions; 2) a regular gap between sessions throughout the treatment period when balancing TT; 3) a preference for protocols with a higher number of acupoints related to ovarian innervation for balancing LH or LH/FSH, regardless of the number and frequency of treatment sessions; 4) FSH modulation appears more affected by a healthy lifestyle and CC intake than by acupuncture treatment. | J Pharmacopuncture. 2023 Jun 30;26(2):105-123. doi: 10.3831/KPI.2023.26.2.105. | Endocrinology | Review |
| 37417606 | Therefore, it is likely that acupuncture combined with traditional Chinese medicine can regulate the endocrine system to increase the release of sex hormones. | Medicine (Baltimore). 2023 Jul 7;102(27):e34310. doi: 10.1097/MD.0000000000034310. | Endocrinology | Review |
| 37773829 | Several studies have shown that acupuncture promotes cortical endocrine involvement by stimulating endogenous opioids such as b-endorphins, enkephalins, predorphins, and endomorphins, and also exerts anti-inflammatory effects via the autonomic nervous system in animal models. | Medicine (Baltimore). 2023 Sep 29;102(39):e34920. doi: 10.1097/MD.0000000000034920. | Endocrinology | Review |
| 37795371 | Acupuncture as multi-targeted therapy for the multifactorial disease obesity: a complex neuro-endocrine-immune interplay | Front Endocrinol (Lausanne). 2023 Sep 18;14:1236370. doi: 10.3389/fendo.2023.1236370. eCollection 2023. | Immunity Endocrinology | Review |
| 37795371 | The neuro-endocrine-immune regulatory mechanisms of acupuncture are now no longer a complete black box. | Front Endocrinol (Lausanne). 2023 Sep 18;14:1236370. doi: 10.3389/fendo.2023.1236370. eCollection 2023. | Immunity Endocrinology | Review |
| 37795371 | Several reviews have found evidence of the effectiveness of acupuncture for the treatment of obesity as well as evidence for its underlying neuro-endocrine mechanisms. | Front Endocrinol (Lausanne). 2023 Sep 18;14:1236370. doi: 10.3389/fendo.2023.1236370. eCollection 2023. | Endocrinology | Review |
| 37795371 | As previously discussed, acupuncture seems to reduce appetite through its neuro-endocrine regulation and reduces cortisol levels and stress. | Front Endocrinol (Lausanne). 2023 Sep 18;14:1236370. doi: 10.3389/fendo.2023.1236370. eCollection 2023. | Endocrinology | Review |
| 37795371 | So far, the mechanisms for the beneficial effects of acupuncture for obesity management have been revealed by several experimental animal studies including regulation of the neuro-endocrine system, low-grade inflammation and gut microbiota brain axis. | Front Endocrinol (Lausanne). 2023 Sep 18;14:1236370. doi: 10.3389/fendo.2023.1236370. eCollection 2023. | Endocrinology | Review |
| 37990288 | Taken together, based on the studies presented here, we hypothesized that acupuncture and EA would alleviate visceral pain in GI disorders by regulating the peripheral, central, and endocrine systems. | Bioelectron Med. 2023 Nov 22;9(1):27. doi: 10.1186/s42234-023-00130-5. | Visceral Pain Endocrinology | Review |
| 38162142 | Some evidence suggests that acupuncture can affect RAAS as well as the central sympathetic and endocrine systems. | Front Cardiovasc Med. 2023 Dec 14;10:1147135. doi: 10.3389/fcvm.2023.1147135. eCollection 2023. | Endocrinology | Review |
| 35647012 | Stress state can lead to the disorder of endocrine and neurotransmitters in patients, and Cor, ET, NE and DA are the representative indicators. | Front Surg. 2022 May 12;9:901638. doi: 10.3389/fsurg.2022.901638. eCollection 2022. | Endocrinology | Clinic |
| 23342207 | In addition, pain also stimulates the sympathetic nervous system, which causes an increase in heart rate, blood pressure, sweat production, endocrine hyper-function, and delays in the patient's recovery from surgery. | Korean J Pain. 2013 Jan;26(1):46-50. doi: 10.3344/kjp.2013.26.1.46. Epub 2013 Jan 4. | Heart Rate Endocrinology Blood Pressure | Clinic |
| 30425466 | Patients were excluded if they met any of the following criteria: MMSE score of less than 24 or dementia, due to various etiologies, preoperative delirium, history of neurological or mental illness, current use of tranquilizers or antidepressants, history of an endocrine or metabolic disorder, recent use of glucocorticoids or other hormones, suffering from infections or chronic inflammatory conditions, intake of anti-inflammatory drugs, unwillingness to complete the experimental procedures, inability to communicate in the preoperative period (language barrier or severe hearing or visual impairment), and alcohol or drug dependence. | Clin Interv Aging. 2018 Oct 24;13:2127-2134. doi: 10.2147/CIA.S183698. eCollection 2018. | Endocrinology | Clinic |
| 30381011 | According to the basic theory of traditional Chinese medicine, surgical trauma could imbalance the state of the human body and disturb the movement of Qi (vital energy), while acupoint stimulation may restore the balance of Qi and facilitate recovery from bodily injury via exerting effects on the central nervous, autonomic nervous, immune, metabolic, and endocrine systems. | Technol Cancer Res Treat. 2018 Jan 1;17:1533033818806477. doi: 10.1177/1533033818806477. | Immunity Endocrinology | Clinic |
| 18388196 | Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder associated with ovulatory dysfunction, hyperandrogenism, abdominal obesity, and insulin resistance. | Endocrinology. 2008 Jul;149(7):3559-68. doi: 10.1210/en.2008-0053. Epub 2008 Apr 3. | Endocrinology | Mechanism |
| 11058557 | For these reasons, the model was used in the present study to investigate the effects of EA (12 treatments, approximately 25 min each, over 30 days) by analyzing NGF in the central nervous system and the endocrine organs, including the ovaries. | Biol Reprod. 2000 Nov;63(5):1497-503. doi: 10.1095/biolreprod63.5.1497. | Endocrinology | Mechanism |
| 29330044 | Our study aims to evaluate the effects of acupuncture on cardiac autonomic modulation (heart rate variability - HRV), behavioural (reactivity) and endocrine (cortisol levels) responses in dogs exposed to sounds of thunder. | Physiol Behav. 2018 Mar 15;186:37-44. doi: 10.1016/j.physbeh.2018.01.006. Epub 2018 Jan 9. | Heart Rate Endocrinology | Mechanism |
| 30204276 | ABSTRACT: Polycystic ovary syndrome (PCOS) is a common reproductive and endocrine disease of unknown aetiology. | Exp Physiol. 2018 Dec;103(12):1618-1632. doi: 10.1113/EP087163. Epub 2018 Oct 23. | Endocrinology | Mechanism |
| 25963796 | Acupuncture with combined manual and low-frequency electrical stimulation, or electroacupuncture (EA), reduces endocrine and reproductive dysfunction in women with polycystic ovary syndrome (PCOS), likely by modulating sympathetic nerve activity or sex steroid synthesis. | Mol Cell Endocrinol. 2015 Sep 5;412:159-69. doi: 10.1016/j.mce.2015.04.026. Epub 2015 May 8. | Endocrinology | Mechanism |
| 2872776 | Acupuncture has many physiological effects on pain control, instinctual behavior, autonomic nervous system and endocrine system. | Acupunct Electrother Res. 1986;11(1):15-23. doi: 10.3727/036012986816359247. | Endocrinology | Mechanism |
| 33341053 | Based on the above data, we performed a systematic bioinformatics analysis of the 41 DEPs, and results showed that these 41 DEPs were predominantly related to 4 KEGG pathways including SNARE interactions in vesicular transport, ferroptosis, endocrine and other factor-regulated calcium reabsorption, and protein digestion and absorption. | Biomed Pharmacother. 2021 Feb;134:111001. doi: 10.1016/j.biopha.2020.111001. Epub 2020 Dec 16. | Endocrinology | Mechanism |
| 27790765 | The effectiveness of low-frequency electroacupuncture in the treatment of metabolic disorders associated with polycystic ovary syndrome (PCOS), an endocrine-metabolic disorder characterized by an imbalance in sex steroid production, is controversial. | Exp Physiol. 2017 Jan 1;102(1):113-127. doi: 10.1113/EP085983. | Endocrinology | Mechanism |
| 1525671 | Stimulation of the rat inner auricular regions that correspond to the human pylorus, lung, trachea, stomach, esophagus, endocrine, and heart acupuncture points evoked potentials in the hypothalamic ventromedial nucleus (HVM), the satiety center. | Brain Res Bull. 1992 Aug;29(2):157-64. doi: 10.1016/0361-9230(92)90021-o. | Endocrinology | Mechanism |
| 26419631 | Some relevant experiments and study about D-IBS found that acupuncture could regulate central nervous system, immune system, endocrine system and GI tract, particularly the excitability of brain functional areas and dorsale medullae spinalis neurons. | BMC Complement Altern Med. 2015 Sep 29;15:340. doi: 10.1186/s12906-015-0863-5. | Immunity Gastrointestinal Tract Endocrinology | Mechanism |
| 19419550 | In the immune and endocrine system, results of microarray have revealed that acupuncture could regulate genes to increase activities of natural killer cell and superoxide dismutase, to keep the cytokines balance between Th1 and Th2, and to induce hypocholesterolemic effects. | J Biomed Sci. 2009 May 6;16(1):46. doi: 10.1186/1423-0127-16-46. | Immunity Endocrinology | Mechanism |
| 34981123 | T2DM is an endocrine disease with high incidence, and patients are prone to metabolic syndromes such as NAFLD. | Biosci Rep. 2022 Jan 28;42(1):BSR20212248. doi: 10.1042/BSR20212248. | Endocrinology | Mechanism |
| 25282142 | Acupuncture regulates autonomic nerve system functions (e.g., modulates blood pressure, heart rate, and sphincter intensity), immune system and inflammatory pathways, and endocrine system functions, such as the release of endorphins and NO, under different pathological conditions. | BMC Complement Altern Med. 2014 Oct 5;14:375. doi: 10.1186/1472-6882-14-375. | Immunity Heart Rate Endocrinology Blood Pressure | Mechanism |
| 37435647 | Therefore, CRH is an important participant in stress response, integrating peripheral and visceral stress-related information to guide neuroendocrine autonomy and behavioral adaptation through the endocrine and neural transmission of PVN. | J Neurophysiol. 2023 Aug 1;130(2):380-391. doi: 10.1152/jn.00156.2023. Epub 2023 Jul 12. | Endocrinology Stress Response | Mechanism |
| 35704659 | Polycystic ovary syndrome (PCOS) is a common reproductive disease, leading to endocrine disorders, metabolic disorders, and infertility in women. | PLoS One. 2022 Jun 15;17(6):e0259609. doi: 10.1371/journal.pone.0259609. eCollection 2022. | Endocrinology | Mechanism |
| 23349861 | Polycystic ovary syndrome (PCOS), a complex female endocrine disorder, is associated with hyperinsulinemia, insulin resistance, dyslipidemia, obesity, and other metabolic derangements. | PLoS One. 2013;8(1):e54357. doi: 10.1371/journal.pone.0054357. Epub 2013 Jan 18. | Endocrinology | Mechanism |
| 23349861 | In clinical studies, low-frequency (2-Hz) electrical stimulation of acupuncture needles placed in skeletal muscles, so-called electro-acupuncture (EA), in combination with manual stimulation of the needles improves endocrine disturbances in women with PCOS. | PLoS One. 2013;8(1):e54357. doi: 10.1371/journal.pone.0054357. Epub 2013 Jan 18. | Endocrinology | Mechanism |
| 23349861 | In obese women with PCOS, acupuncture without electrical stimulation is superior to metformin for improving endocrine disturbances, while both treatments improve insulin sensitivity and lipid profile. | PLoS One. 2013;8(1):e54357. doi: 10.1371/journal.pone.0054357. Epub 2013 Jan 18. | Endocrinology | Mechanism |
| 24908398 | The possibility that EA at Zusanli, acting at a different CNS location from SP9 EA, causes release of an endocrine factor or neuromediator that affects macrophages and TNF-α release also needs investigation. | BMC Complement Altern Med. 2014 Jun 7;14:186. doi: 10.1186/1472-6882-14-186. | Endocrinology | Mechanism |
| 15046638 | Polycystic ovary syndrome (PCOS) is a complex endocrinological disorder, associated with ovulatory dysfunction and infertility, hyperandrogenism, hyperinsulinemia and insulin resistance, and progression to type II diabetes. | Reprod Biol Endocrinol. 2004 Mar 26;2:16. doi: 10.1186/1477-7827-2-16. | Endocrinology | Mechanism |
| 15046638 | injection of estradiol valerate (EV), develop an anovulatory state that shares many endocrinological and morphological characteristics of human PCOS, and it is assumed that the activity of the ovarian sympathetic nerves in PCO rats is higher than in normal rats. | Reprod Biol Endocrinol. 2004 Mar 26;2:16. doi: 10.1186/1477-7827-2-16. | Endocrinology | Mechanism |
| 27179524 | While it may modulate organ function directly via the central nervous system efferent output, it can also elicit these effects via the neuro-endocrine axis. | Lung. 2016 Aug;194(4):535-46. doi: 10.1007/s00408-016-9899-7. Epub 2016 May 14. | Endocrinology | Mechanism |
| 31600836 | The hypothalamus is an essential region in regulating autonomic and endocrine function and maintaining homeostasis. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Endocrinology | Mechanism |
| 34630618 | Acupuncture has been reported to play a regulatory role in the neuro-endocrine-immune network under stress. | Evid Based Complement Alternat Med. 2021 Oct 1;2021:7992688. doi: 10.1155/2021/7992688. eCollection 2021. | Immunity Endocrinology | Mechanism |
| 34630618 | Mechanistically, acupuncture clears the meridians, regulates qi and the mind by stimulating the acupoints, and modulates the release of neurotransmitters and hormones in the neuro-endocrine-immune system. | Evid Based Complement Alternat Med. 2021 Oct 1;2021:7992688. doi: 10.1155/2021/7992688. eCollection 2021. | Immunity Endocrinology | Mechanism |
| 25206746 | This might relate to normalization of the endocrine system by electroacupuncture, and of the HPA axis in particular. | Neural Regen Res. 2014 Jan 1;9(1):76-83. doi: 10.4103/1673-5374.125333. | Endocrinology | Mechanism |
| 36636219 | The HPA axis is a nerve endocrine system that regulates the stress reaction of the body. | Heliyon. 2022 Dec 22;8(12):e12574. doi: 10.1016/j.heliyon.2022.e12574. eCollection 2022 Dec. | Endocrinology Stress Response | Mechanism |
| 28806763 | As we know that body temperature is regulated by thermoregulation center, which is located in hypothalamus, and endocrine and sympathetic-adrenal endocrine system were involved in this regulation. | PLoS One. 2017 Aug 14;12(8):e0181948. doi: 10.1371/journal.pone.0181948. eCollection 2017. | Endocrinology | Mechanism |
| 26064171 | It also activates neurohumoral factors and immunocompetent systems and regulates the endocrine system. | Evid Based Complement Alternat Med. 2015;2015:687196. doi: 10.1155/2015/687196. Epub 2015 May 3. | Immunity Endocrinology | Mechanism |
| 25206591 | The hypothalamus plays an important role in the homeostatic regulation of physiological functions, and helps link the body's nervous and endocrine systems. | Neural Regen Res. 2013 Jan 25;8(3):218-25. doi: 10.3969/j.issn.1673-5374.2013.03.003. | Endocrinology | Mechanism |
| 33062027 | The effect of acupuncture on weight loss is related to various mechanisms, such as regulation of the endocrine system, promotion of digestion, attenuation of oxidative stress, and alteration of bacterial diversity. | Evid Based Complement Alternat Med. 2020 Sep 24;2020:8764507. doi: 10.1155/2020/8764507. eCollection 2020. | Endocrinology | Mechanism |
| 33062027 | For acupoints selection, studies show that ST36 can regulate multiple systems, such as the digestive system, immune system, and endocrine system. | Evid Based Complement Alternat Med. 2020 Sep 24;2020:8764507. doi: 10.1155/2020/8764507. eCollection 2020. | Immunity Gastrointestinal Tract Endocrinology | Mechanism |
| 33478541 | It has been reported that NGF could promote the proliferation and differentiation of bone cells and inhibit the formation of osteoclasts through endocrine factors such as other neuropeptides and hormones, thereby promoting fracture healing. | J Orthop Surg Res. 2021 Jan 21;16(1):74. doi: 10.1186/s13018-021-02220-z. | Endocrinology | Mechanism |
| 33478541 | It has been reported that NGF could promote the proliferation and differentiation of bone cells and inhibit the formation of osteoclasts through endocrine factors, such as other neuropeptides and hormones, thereby promoting fracture healing. | J Orthop Surg Res. 2021 Jan 21;16(1):74. doi: 10.1186/s13018-021-02220-z. | Endocrinology | Mechanism |
| 34757591 | Subsequently, insulin secretion decreased and impaired pancreatic endocrine function was restored through the TRPV1 channel (SP/CGRP)-insulin circuit. | Mol Neurobiol. 2022 Jan;59(1):703-716. doi: 10.1007/s12035-021-02609-1. Epub 2021 Nov 10. | Endocrinology | Mechanism |
| 34757591 | It can facilitate weight control by regulating the nervous, endocrine, and digestive systems. | Mol Neurobiol. 2022 Jan;59(1):703-716. doi: 10.1007/s12035-021-02609-1. Epub 2021 Nov 10. | Gastrointestinal Tract Endocrinology | Mechanism |
| 34757591 | A potential mechanism for the hypoglycemic effect of acupuncture is a neuroendocrine pathway involving crosstalk among the endocrine, nervous, and immune systems. | Mol Neurobiol. 2022 Jan;59(1):703-716. doi: 10.1007/s12035-021-02609-1. Epub 2021 Nov 10. | Immunity Endocrinology | Mechanism |
| 34757591 | Intrapancreatic ganglia constitute a complex information-processing center that contains various neurotransmitters and forms an endogenous neural network, which has a major influence on pancreatic endocrine function; those neurotransmitters including choline acetyltransferase (ChAT) and neuropeptide Y (NPY) control inflammatory status, cocaine, and amphetamine-regulated transcript (CART-PT) to promote the secretion of glucagon-like peptide-1 (GLP-1) and a promising axis in TRPV1 channel (SP/CGRP)-insulin circuit. | Mol Neurobiol. 2022 Jan;59(1):703-716. doi: 10.1007/s12035-021-02609-1. Epub 2021 Nov 10. | Endocrinology | Mechanism |
| 34757591 | Consequently, we hypothesized that EA at ST25 will lead to a hypoglycemic effect through neural regulation of pancreatic endocrine secretion. | Mol Neurobiol. 2022 Jan;59(1):703-716. doi: 10.1007/s12035-021-02609-1. Epub 2021 Nov 10. | Endocrinology | Mechanism |
| 34757591 | The pan-neuronal marker protein gene product 9.5 (PGP9.5) was first examined by WB to explore the hypoglycemic effect of electroacupuncture at ST25 through neural regulation of pancreatic endocrine secretion. | Mol Neurobiol. 2022 Jan;59(1):703-716. doi: 10.1007/s12035-021-02609-1. Epub 2021 Nov 10. | Endocrinology | Mechanism |
| 34757591 | Pancreatic Endocrine Function Was Restored Through the TRPV1-(SP/CGRP)-β Cell Circuit | Mol Neurobiol. 2022 Jan;59(1):703-716. doi: 10.1007/s12035-021-02609-1. Epub 2021 Nov 10. | Endocrinology | Mechanism |
| 34757591 | On the basis of the findings obtained with the observation of insulin in rat pancreas, we further evaluated the results of immunofluorescence staining and identified the expression of TRPV1 and insulin in rat pancreas to explore the neural regulation of pancreatic endocrine secretion through EA (Fig. | Mol Neurobiol. 2022 Jan;59(1):703-716. doi: 10.1007/s12035-021-02609-1. Epub 2021 Nov 10. | Immunity Endocrinology | Mechanism |
| 34757591 | As mentioned before, PINS constitute a complex information-processing center that includes various neurotransmitters and forms an endogenous neural network, which has an important influence on pancreatic endocrine function. | Mol Neurobiol. 2022 Jan;59(1):703-716. doi: 10.1007/s12035-021-02609-1. Epub 2021 Nov 10. | Endocrinology | Mechanism |
| 34757591 | Further explanation of our study focuses on the restoration of pancreatic endocrine function by EA at ST25 through the TRPV1 channel (SP/CGRP)-β cell circuit. | Mol Neurobiol. 2022 Jan;59(1):703-716. doi: 10.1007/s12035-021-02609-1. Epub 2021 Nov 10. | Endocrinology | Mechanism |
| 34757591 | However, the islets of Langerhans make up only about 2% of the mass of the pancreas, so extrapolating the results from the whole pancreas to the endocrine pancreas is difficult. | Mol Neurobiol. 2022 Jan;59(1):703-716. doi: 10.1007/s12035-021-02609-1. Epub 2021 Nov 10. | Endocrinology | Mechanism |
| 37303036 | In this study, we investigated the mechanism of action of acupuncture in treating abnormal follicle development in PCOS based on the understanding of PCOS based on TCM theory and the analysis of acupuncture points based on clinical experience combined with meridian selection and verified the effects of acupuncture on reproductive endocrine levels, ovarian granulosa cell apoptosis,miR-21-3p and LncMEG3 expression in PCOS rats. | Biol Res. 2023 Jun 12;56(1):31. doi: 10.1186/s40659-023-00441-6. | Endocrinology | Mechanism |
| 37303036 | Abnormal follicular development and metabolic and endocrine disorders are the main pathological manifestations of PCOS, and hypothalamic gonadotropin-releasing hormone and ovarian oestrogen together regulate this process. | Biol Res. 2023 Jun 12;56(1):31. doi: 10.1186/s40659-023-00441-6. | Endocrinology | Mechanism |
| 37303036 | The abnormal secretion of FSH and LH from the pituitary gland, together with abnormal levels of E2, AMH, and T, promotes abnormal follicular cell development and endocrine disorders, which in turn affect polycystic changes in ovarian morphology. | Biol Res. 2023 Jun 12;56(1):31. doi: 10.1186/s40659-023-00441-6. | Endocrinology | Mechanism |
| 23878591 | As a result, the active components which come from vessels, nervous fibers, immunity system, and endocrine system interacted with each other to form a functional coupling structure. | Evid Based Complement Alternat Med. 2013;2013:160651. doi: 10.1155/2013/160651. Epub 2013 Jun 26. | Immunity Endocrinology | Mechanism |
| 23878591 | For example, different caliber blood vessels closely related to the different types of neural endings which had different neurotransmitters and peptides regulated the flow of the peripheral blood circulation precisely then influenced the transport and distribution of body fluid and took part in the stress response and nerve-endocrine-immunity procedure. | Evid Based Complement Alternat Med. 2013;2013:160651. doi: 10.1155/2013/160651. Epub 2013 Jun 26. | Immunity Endocrinology Stress Response Circulation | Mechanism |
| 29785197 | Researches have shown that the body's inherent regulatory system is neuroendocrine-immune (NEI) network, including nervous system, endocrine system, and immune system, which is the biological basis to maintain the body's homeostasis. | Evid Based Complement Alternat Med. 2018 Jan 29;2018:9260630. doi: 10.1155/2018/9260630. eCollection 2018. | Immunity Endocrinology | Mechanism |
| 29785197 | 55 NEI common signaling molecules in rats serum, supernatants form the right ST36 acupoint, and hind footpad tissue were detected in this experiment, including 13 neurotransmitters or neuropeptides, 18 endocrine hormones, and 24 cytokines. | Evid Based Complement Alternat Med. 2018 Jan 29;2018:9260630. doi: 10.1155/2018/9260630. eCollection 2018. | Endocrinology | Mechanism |
| 37635258 | The treatment of diseases by acupuncture is not done by a single signal molecule, signal pathway, nervous system, endocrine system or immune system alone. | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Immunity Endocrinology | Mechanism |
| 25887143 | As an initiator of the endocrine system, the hypothalamus plays a key role in HPAA. | BMC Complement Altern Med. 2015 Mar 27;15:87. doi: 10.1186/s12906-015-0625-4. | Endocrinology | Mechanism |