- The advantages of acupuncture anesthesia in clinical practice
In clinical practice, acupuncture anesthesia presents a multitude of advantages, pivotal among these being Body System Protection. This technique supports the body's natural defenses, reducing the physiological stress often associated with surgical procedures. By modulating the body's response to pain, acupuncture anesthesia allows for a lower Dosage of Medication, significantly reducing the potential for drug-related side effects. Furthermore, this approach plays a crucial role in Emotion Regulation, helping patients maintain a calm and stable emotional state, which is essential for a positive surgical outcome. The impact of acupuncture on the nervous system not only aids in Pain Relief but also promotes Enhanced Recovery After Surgery. Patients tend to experience faster recuperation times, attributed to the holistic nature of this method. Additionally, acupuncture anesthesia is associated with a Lower Incidence of Side Effects compared to conventional anesthetics. Its ability to modulate and balance the body's responses makes it an invaluable tool in the realm of modern medicine, offering a safer, more patient-centered approach to pain management and recovery.
- Brain Protection
- Acupuncture anesthesia plays a vital role in brain surgeries, ensuring precise and safe anesthesia, reducing the risk of neurological complications, and supporting optimal cognitive function.
- Lung Protection
- Acupuncture anesthesia reduces post-operative lung complications, aiding in rapid lung function recovery, particularly beneficial for lung surgeries.
- Neuroprotection
- Acupuncture anesthesia is crucial for safeguarding the nervous system, reducing nerve injuries, and preventing the progression of neurological disorders.
- Kidney
- Acupuncture anesthesia alleviates stress on the kidneys, reducing the risk of kidney injury, particularly valuable in kidney surgeries.
- Gastrointestinal Tract
- Acupuncture anesthesia supports gastrointestinal health, reducing the risk of post-operative digestive issues, and ensuring a smoother recovery.
- Cardiovascular
- Acupuncture anesthesia eases the cardiovascular system's burden, reducing the risk of cardiovascular complications, especially in cardiac surgeries.
- Myocardium
- Acupuncture anesthesia aids in protecting the myocardium, minimizing adverse effects on heart muscle, ensuring cardiac health.
- Cognitive Function
- Through emotional stability and neuroprotection, acupuncture anesthesia helps preserve cognitive function, reducing the risk of post-operative cognitive impairment.
- Motor Function
- Acupuncture anesthesia improves motor function, aiding in post-operative mobility, and enhancing overall quality of life.
- Language Function
- Acupuncture anesthesia supports language function rehabilitation, assisting patients in regaining their communication skills.
- Learning and Memory Ability
- Acupuncture anesthesia, by reducing post-operative pain and emotional instability, enhances learning and memory ability, promoting a speedy recovery.
Acupuncture anesthesia for Body System Protection-Gastrointestinal Tract
| PMID | Evidence | Source | Keyword | Type |
|---|---|---|---|---|
| 10100029 | Voluminous data support the effect of acupuncture on the physiology of the GI tract, including acid secretion, motility, neurohormonal changes, and changes in sensory thresholds. | J Altern Complement Med. 1999 Feb;5(1):27-45. doi: 10.1089/acm.1999.5.27. | Gastrointestinal Tract | Review |
| 10100029 | Although there are few prospective randomized clinical studies, the well-documented physiological basis of acupuncture effects on the GI tract, and the extensive history of successful clinical use of acupuncture, makes this a promising modality that warrants further investigation. | J Altern Complement Med. 1999 Feb;5(1):27-45. doi: 10.1089/acm.1999.5.27. | Gastrointestinal Tract | Review |
| 12754882 | Acupuncture also affects the upper GI tract, decreasing acid secretion and repressing gastric arrhythmias. | Harefuah. 2003 Apr;142(4):297-300, 316. | Gastrointestinal Tract | Review |
| 16799260 | Reports on the curative effects of acupuncture on various digestive and urological disorders are also reviewed briefly. | J Pharmacol Sci. 2006;100(5):443-59. doi: 10.1254/jphs.crj06004x. | Gastrointestinal Tract | Review |
| 22379794 | The authors of the present paper make a review about its research progress in recent ten years from (1) effect of acupuncture on VIP functional activities of the gastrointestinal tract; (2) involvement of VIP in electroacupuncture (EA) induced improvement of gastric mucosal and cerebral blood flow (3) effect of EA on functions of VIP being as a neurotransmitter; (4) effect of EA on VIP-involved immune regulation function. | Zhen Ci Yan Jiu. 2011 Dec;36(6):453-6. | Immunity Gastrointestinal Tract Blood Flow | Review |
| 25543450 | Literature regarding the basic research of acupuncture-moxibustion serum for last more than 10 years is reviewed, and the effects of acupuncture-moxibustion serum on respiratory system, digestive system, cardiovascular system, nervous system, immune system, anti-aging, bone metabolism and anti-cancer are summarized, hoping to provide references for clinical treatment and evidence-based medicine. | Zhongguo Zhen Jiu. 2014 Oct;34(10):1042-6. | Immunity Gastrointestinal Tract Cardiovascular | Review |
| 26480578 | Of them, 3 papers discussed the effects of acupuncture on progressing of lung cancer; 4 articles confirmed that acupuncture could reduce myelosuppression and digestive tract reactions induced by radiotherapy and chemotherapy; 6 papers showed that acupuncture could relieve pain or fatigue of lung cancer; 3 papers indicated that acupuncture could palliate dyspnea in lung cancer patients. | Zhongguo Zhen Jiu. 2015 Jun;35(6):638-40. | Gastrointestinal Tract | Review |
| 30707414 | Somato-visceral reflex was suggested to be strongly associated with the effects of acupuncture changing the motor activity of the gastrointestinal tract. | Chin J Integr Med. 2020 Apr;26(4):310-320. doi: 10.1007/s11655-019-3150-3. Epub 2019 Feb 1. | Gastrointestinal Tract | Review |
| 9494036 | For decades, acupuncture and electroneedling treatments have been used, predominately in the Eastern countries, in the management of patients with compromised cardiovascular and digestive functions. | Disabil Rehabil. 1998 Feb;20(2):41-8. doi: 10.3109/09638289809166052. | Gastrointestinal Tract Cardiovascular | Review |
| 15932647 | These exemplary studies indicate CAM therapies that may be considered cost-effective compared to usual care for various conditions: acupuncture for migraine, manual therapy for neck pain, spa therapy for Parkinson's, self-administered stress management for cancer patients undergoing chemotherapy, pre- and post-operative oral nutritional supplementation for lower gastrointestinal tract surgery, biofeedback for patients with ""functional"" disorders (eg, irritable bowel syndrome), and guided imagery, relaxation therapy, and potassium-rich diet for cardiac patients. | BMC Complement Altern Med. 2005 Jun 2;5:11. doi: 10.1186/1472-6882-5-11. | Gastrointestinal Tract | Review |
| 15932647 | The exemplary studies summarized in Table 5 indicate that a number of CAM therapies may be considered cost-effective compared to usual care for a number of conditions: acupuncture for migraine, manual therapy for neck pain, spa therapy for Parkinson's, complementary guided imagery for cardiac surgery patients, complementary relaxation therapy for patients with previous myocardial infarction, complementary self-administered stress management for cancer patients undergoing chemotherapy, complementary pre- and post-operative oral nutritional supplementation for lower gastrointestinal tract surgery, potassium-rich diet (rather than potassium supplements) for postoperative cardiac patients, and biofeedback for patients with ""functional"" disorders such as irritable bowel syndrome. | BMC Complement Altern Med. 2005 Jun 2;5:11. doi: 10.1186/1472-6882-5-11. | Gastrointestinal Tract | Review |
| 24088418 | Of acupuncture-related techniques, moxibustion or moxa, frequently used in conjunction with acupuncture needling, uses heat stimulation generated by burning herbal preparations containing dried Artemisia vulgaris or mugwort leaves on targeted acupuncture points to improve general health and treat chronic conditions such as arthritis and digestive disorders. | BMC Complement Altern Med. 2013 Oct 2;13:247. doi: 10.1186/1472-6882-13-247. | Gastrointestinal Tract | Review |
| 24206922 | In china, acupuncture and traditional Chinese medications have been used to treat gastrointestinal tract disorders over 1500Â years. | BMC Complement Altern Med. 2013 Nov 9;13:311. doi: 10.1186/1472-6882-13-311. | Gastrointestinal Tract | Review |
| 24206922 | It is documented in ancient Chinese medical books that acupuncture can treat many digestive symptoms such as stomach fullness, nausea, abdominal pain, vomiting, loss of appetite and bloating. | BMC Complement Altern Med. 2013 Nov 9;13:311. doi: 10.1186/1472-6882-13-311. | Gastrointestinal Tract Nausea and Vomiting | Review |
| 24206922 | In recent years, with the accumulating evidence of acupuncture for gastrointestinal tract and definite diagnosis of diabetic gastroparesis, some acupuncturists in China have realized that acupuncture might have potential effects in treating diabetic gastroparesis. | BMC Complement Altern Med. 2013 Nov 9;13:311. doi: 10.1186/1472-6882-13-311. | Gastrointestinal Tract | Review |
| 31467579 | Many studies have confirmed that acupuncture in the stomach meridian point, especially in the Zusanli point (ST36), has a benign regulatory effect on the digestive system, especially on the gastrointestinal functions. | Evid Based Complement Alternat Med. 2019 Jul 31;2019:8138017. doi: 10.1155/2019/8138017. eCollection 2019. | Gastrointestinal Tract | Review |
| 32215037 | Acupuncture might be useful in reducing injuries induced by sepsis in cardiac, lung, kidney, liver, gastrointestinal tract, and immune system. | Evid Based Complement Alternat Med. 2020 Mar 7;2020:3620741. doi: 10.1155/2020/3620741. eCollection 2020. | Immunity Gastrointestinal Tract Kidney | Review |
| 32215037 | The present study indicated that acupuncture at ST36 could be useful in reducing sepsis-induced injuries in heat, lung, kidney, liver, gastrointestinal tract, and immune system. | Evid Based Complement Alternat Med. 2020 Mar 7;2020:3620741. doi: 10.1155/2020/3620741. eCollection 2020. | Immunity Gastrointestinal Tract Kidney | Review |
| 34281592 | Evidence has shown that acupuncture has anti-inflammatory actions that affect multiple body systems, including the immune, locomotory, endocrine, nervous, digestive, and respiratory systems, by downregulating pro-inflammatory M1 and upregulating anti-inflammatory M2 macrophages, as well as by modulating associated cytokine secretion. | Chin Med. 2021 Jul 19;16(1):56. doi: 10.1186/s13020-021-00466-7. | Immunity Gastrointestinal Tract Endocrinology | Review |
| 34281592 | Therefore, it can be seen that ST36 is mostly applyied to inflammatory diseases of the digestive system such as colitis, postoperative ileus, peritonitis and pancreatitis, and the ST36 acupuncture action in regulating gastrointestinal inflammation may be mediated by α7-nicotinic acetylcholine receptor signaling pathways. | Chin Med. 2021 Jul 19;16(1):56. doi: 10.1186/s13020-021-00466-7. | Gastrointestinal Tract | Review |
| 34281592 | Through a review of the relevant literature, we have found that the anti-inflammatory effects of acupuncture in numerous diseases, including diseases of the immune, locomotory, nervous, digestive and respiratory systems, are closely related to macrophages together with their associated cellular signaling and cytokines. | Chin Med. 2021 Jul 19;16(1):56. doi: 10.1186/s13020-021-00466-7. | Immunity Gastrointestinal Tract | Review |
| 34992414 | This study comprehensively reviews and presents literature from the last five years, showing that acupuncture indeed exerts strong anti-inflammatory effects in multiple biological systems, namely, the immune, digestive, respiratory, nervous, locomotory, circulatory, endocrine, and genitourinary systems. | J Inflamm Res. 2021 Dec 21;14:7191-7224. doi: 10.2147/JIR.S341581. eCollection 2021. | Immunity Gastrointestinal Tract Endocrinology Circulation | Review |
| 34992414 | Acupuncture offers a great advantage in consolidating the curative effect, in reducing the recurrence rate, and in improving immunity in digestive system diseases, such as hepatitis, acute/chronic pancreatitis, chronic atrophic gastritis, inflammatory bowel disease (IBD), and other inflammatory diseases (Table 2). | J Inflamm Res. 2021 Dec 21;14:7191-7224. doi: 10.2147/JIR.S341581. eCollection 2021. | Immunity Gastrointestinal Tract | Review |
| 34992414 | Apart from macrophages, acupuncture also alleviates inflammatory diseases in the digestive system by regulating mast cells. | J Inflamm Res. 2021 Dec 21;14:7191-7224. doi: 10.2147/JIR.S341581. eCollection 2021. | Gastrointestinal Tract | Review |
| 35547876 | The World Health Organization has recommended 107 indications for acupuncture, including various disorders of the nervous system, musculoskeletal system, respiratory system, and digestive system. | Front Oncol. 2022 Apr 25;12:864046. doi: 10.3389/fonc.2022.864046. eCollection 2022. | Gastrointestinal Tract | Review |
| 35721049 | Studies were excluded if they (1) were investigating patients having chronic pharyngolaryngitis, severe digestive system diseases, persistent hiccups, severe nausea and retching, proven tumors in the upper digestive tract, severe mental disorders, or uncontrolled cardiopulmonary disease; (2) were only comparing different types of acupunctures without a comparison group of no treatment, placebo or sham acupuncture, medicine, or other conservative therapies; and (3) were not RCTs or were quasi-RCTs, or without a clear description of interventions, or did not provide outcome data. | Front Med (Lausanne). 2022 Jun 3;9:865035. doi: 10.3389/fmed.2022.865035. eCollection 2022. | Gastrointestinal Tract Nausea and Vomiting | Review |
| 35725779 | In the upper GI tract, the affect induced by acupuncture is site specific. | Blood Rev. 2022 Nov;56:100985. doi: 10.1016/j.blre.2022.100985. Epub 2022 Jun 13. | Gastrointestinal Tract | Review |
| 35725779 | As for the lower GI tract, experimental studies showed that electroacupuncture at ST-36 stimulated distal colonic motility by modulating sacral parasympathetic efferent pathway which may imply that acupuncture might help in reducing constipation in cancer patients. | Blood Rev. 2022 Nov;56:100985. doi: 10.1016/j.blre.2022.100985. Epub 2022 Jun 13. | Gastrointestinal Tract | Review |
| 35782337 | In addition, new evidence also suggests that NAFLD is closely related to intestinal flora, and acupuncture has been proved to be involved in the treatment of various diseases, including nervous system diseases, endocrine diseases, and digestive system diseases, by regulating intestinal flora. | Gastroenterol Res Pract. 2022 Jun 22;2022:5259088. doi: 10.1155/2022/5259088. eCollection 2022. | Gastrointestinal Tract Endocrinology | Review |
| 35922617 | The inhibitory effect of acupuncture on nausea and vomiting may be through the following mechanisms: (1) blocking the transmission of 5-HT3 and increasing the release of endogenous β-endorphins in the cerebrospinal fluid; (2) regulating the function of the vagus nerve, the secretion of hormones, and the blood circulation of the gastrointestinal tract; and (3) playing an indirect preventive effect by reducing the application of opioid analgesics. | Pain Ther. 2022 Dec;11(4):1095-1112. doi: 10.1007/s40122-022-00415-8. Epub 2022 Aug 3. | Gastrointestinal Tract Nausea and Vomiting Circulation | Review |
| 36316824 | Focal acupuncture on BL18, BL20, and BL22 can reduce inflammation of the intertransverse ligament or tension of the spinal muscles, thereby improving pathological conditions of the sympathetic nervous system that strongly innervates the GI tract and affects motility, secretion, blood flow, and immune cells. | Medicine (Baltimore). 2022 Oct 28;101(43):e29878. doi: 10.1097/MD.0000000000029878. | Immunity Gastrointestinal Tract Blood Flow | Review |
| 36316824 | However, several acupuncture points are related to the digestive system, including BL18, BL20, BL21, and BL22, BL20, BL21, and BL22 are on the back, 1.5 cun lateral to the lower border of the spinous process of the T11. | Medicine (Baltimore). 2022 Oct 28;101(43):e29878. doi: 10.1097/MD.0000000000029878. | Gastrointestinal Tract | Review |
| 36316824 | Acupuncture on the diaphragm can stimulate the vagus nerve and sympathetic nerves, thereby regulating digestive function directly. | Medicine (Baltimore). 2022 Oct 28;101(43):e29878. doi: 10.1097/MD.0000000000029878. | Gastrointestinal Tract | Review |
| 36316824 | Considering attachment of the diaphragm to the thoracic, lumbar vertebra, and 12th rib, acupuncture on the BL20 or near back-shu acupoints may affect GI function directly through the connection between the diaphragm and the GI tract or esophageal hiatus and indirectly by structures connected with the diaphragm, including the lesser omentum and hepatogastric ligament. | Medicine (Baltimore). 2022 Oct 28;101(43):e29878. doi: 10.1097/MD.0000000000029878. | Gastrointestinal Tract | Review |
| 36316824 | According to these explanatory analyses, we presented an accurate method of inserting an acupuncture needle into the BL18 or BL20 for treating GI tract disease by inserting the needle into the lower part of the 12th rib from the same position as the vertical insertion into the upper part of the transverse process of 1st thoracic bone to the outer side. | Medicine (Baltimore). 2022 Oct 28;101(43):e29878. doi: 10.1097/MD.0000000000029878. | Gastrointestinal Tract | Review |
| 37038228 | Acupuncture is mainly recommended for diseases involving the digestive system, circulatory system, and neurodevelopmental disorders, with studies showing that its efficacy is superior to conventional treatment. | Chin Med. 2023 Apr 10;18(1):38. doi: 10.1186/s13020-023-00743-7. | Gastrointestinal Tract Circulation | Review |
| 37038228 | Acupuncture-related systemic reactions, including digestive system symptoms, tiredness, discomfort, psychological disorder, fever, and heat/sweating, were reported in 113SRs. | Chin Med. 2023 Apr 10;18(1):38. doi: 10.1186/s13020-023-00743-7. | Gastrointestinal Tract | Review |
| 37351066 | However, the specific mechanisms underlying acupuncture treatment in the GI tract have not yet been elucidated. | Front Med (Lausanne). 2023 Jun 7;10:1167356. doi: 10.3389/fmed.2023.1167356. eCollection 2023. | Gastrointestinal Tract | Review |
| 37351066 | We expect that our report will contribute to further experimental and clinical trials of acupuncture treatment for stomach-related diseases and digestive system disorders. | Front Med (Lausanne). 2023 Jun 7;10:1167356. doi: 10.3389/fmed.2023.1167356. eCollection 2023. | Gastrointestinal Tract | Review |
| 37363406 | The effectiveness and safety of acupuncture therapy for various complex diseases of nervous system, digestive system, respiratory system, motor system and other systems have been supported by high-quality evidence from clinical research and its effect mechanism has gained increasing attention. | World J Acupunct Moxibustion. 2023 Mar 17. doi: 10.1016/j.wjam.2023.03.002. | Gastrointestinal Tract | Review |
| 37655096 | As a type of non-pharmacological therapy with a long history in China, acupuncture has been regarded as an effective treatment for diseases of the gastrointestinal tract for thousands of years. | Front Oncol. 2023 Aug 15;13:1232754. doi: 10.3389/fonc.2023.1232754. eCollection 2023. | Gastrointestinal Tract | Review |
| 37655096 | The exact biological mechanisms of the effects of acupuncture on gastrointestinal tract functions are still being researched. | Front Oncol. 2023 Aug 15;13:1232754. doi: 10.3389/fonc.2023.1232754. eCollection 2023. | Gastrointestinal Tract | Review |
| 37732301 | Notably, the afferent signals stemming from acupuncture at LI4 and Sibai points were observed to converge onto the same nucleus tractus solitarius neurons, which exert a dual influence on both the digestive system and the brain. | Front Neurosci. 2023 Sep 4;17:1251470. doi: 10.3389/fnins.2023.1251470. eCollection 2023. | Gastrointestinal Tract | Review |
| 37795371 | Combined, this evidence potentially underscores an association between acupuncture and changes in gut microbiota in several disease models, including but not limited to obesity and disorders of the gastrointestinal tract, although the causality remains to be further evaluated. | Front Endocrinol (Lausanne). 2023 Sep 18;14:1236370. doi: 10.3389/fendo.2023.1236370. eCollection 2023. | Gastrointestinal Tract | Review |
| 37799620 | Moreover, some studies have reported that acupuncture increases the expression of proteins associated with the tight junctions found in cells of the gastrointestinal tract, such as Zonula ocludens-1, occludin, and claudin-1. | J Pharmacopuncture. 2023 Sep 30;26(3):211-226. doi: 10.3831/KPI.2023.26.3.211. | Gastrointestinal Tract | Review |
| 37810368 | The evidence indicates that acupuncture can improve the respiratory, digestive, nervous, and mental and psychological symptoms related to COVID-19 by inhibiting immune inflammatory reactions, regulating intestinal flora, mitochondrial function, oxidative stress level, cardiomyocyte apoptosis, neurotransmitter release, and HPA axis activity, and alleviating basic diseases such as diseases of the vascular system. | Acupunct Herb Med. 2023 Jun;3(2):83-95. doi: 10.1097/HM9.0000000000000062. Epub 2023 Mar 13. | Immunity Gastrointestinal Tract | Review |
| 37810368 | Using Cytoscape 3.6.0 software for the visual display, a complex network analysis was performed of acupuncture points and symptoms related to the respiratory, digestive, nervous, and cardiovascular systems and psycho-psychological disorders of patients with COVID-19. | Acupunct Herb Med. 2023 Jun;3(2):83-95. doi: 10.1097/HM9.0000000000000062. Epub 2023 Mar 13. | Gastrointestinal Tract Cardiovascular | Review |
| 37810368 | Acupuncture treatment for COVID-19-related symptoms related to the respiratory, digestive, and nervous systems | Acupunct Herb Med. 2023 Jun;3(2):83-95. doi: 10.1097/HM9.0000000000000062. Epub 2023 Mar 13. | Gastrointestinal Tract | Review |
| 37810368 | Acupuncture for digestive symptoms related to COVID-19 | Acupunct Herb Med. 2023 Jun;3(2):83-95. doi: 10.1097/HM9.0000000000000062. Epub 2023 Mar 13. | Gastrointestinal Tract | Review |
| 37810368 | Although acupuncture for COVID-19 digestive symptoms has not been evaluated in a clinical trial, there is abundant evidence of its effect on digestive symptoms. | Acupunct Herb Med. 2023 Jun;3(2):83-95. doi: 10.1097/HM9.0000000000000062. Epub 2023 Mar 13. | Gastrointestinal Tract | Review |
| 23188543 | Study participants with the following intraoperative events also were excluded: resection incorporating the upper GI tract, gross fecal spillage, need to leave nasogastric tube in postoperatively, decision to give epidural anesthesia postoperatively, and complications during surgery requiring direct postoperative transfer to intensive care unit. | Ann Surg Oncol. 2013 Apr;20(4):1164-9. doi: 10.1245/s10434-012-2759-7. Epub 2012 Nov 28. | Gastrointestinal Tract | Clinic |
| 33154688 | This may be because, first, electroacupuncture at PC6 (Neiguan) and ST-36 (Zusanli) could cause free xefxacx82ow of qi, regulate the digestive system, and help relax the gastrointestinal track. | Nat Sci Sleep. 2020 Oct 27;12:809-819. doi: 10.2147/NSS.S270739. eCollection 2020. | Gastrointestinal Tract | Clinic |
| 36098938 | Acupuncture protects the gastrointestinal tract by regulating gastrointestinal dynamics to promote venting and allows the patient to quickly resume normal diet. | Pain Ther. 2022 Dec;11(4):1327-1339. doi: 10.1007/s40122-022-00429-2. Epub 2022 Sep 13. | Gastrointestinal Tract | Clinic |
| 36098938 | PONV is one of the most common gastrointestinal tract complications after anesthesia. | Pain Ther. 2022 Dec;11(4):1327-1339. doi: 10.1007/s40122-022-00429-2. Epub 2022 Sep 13. | Gastrointestinal Tract | Clinic |
| 36749304 | Conventional analgesia medicine could increase the risk of nausea, vomiting and other digestive system side effects, abnormal liver/ renal functions, and inhibit bone formation and healing (Zhao & Davis,). | Brain Behav. 2023 Mar;13(3):e2913. doi: 10.1002/brb3.2913. Epub 2023 Feb 7. | Gastrointestinal Tract Side Effects Nausea and Vomiting Kidney | Clinic |
| 29231528 | CONCLUSIONS: (1) EA at digestive system-related lower he-sea points, through IL-1beta, HMGB 1 and nAchR alpha7, could regulate immune response, lighten inflammatory reaction and reduce mucosal injury, which could realize the intervention effect on AGML rats. | Zhongguo Zhen Jiu. 2016 Oct 12;36(10):1071-1076. doi: 10.13703/j.0255-2930.2016.10.018. | Immunity Gastrointestinal Tract | Mechanism |
| 6727561 | Effects of acupuncture and electroacupuncture (EAP) on gastric secretion were studied in the interdigestive state of five conscious dogs prepared with esophagostomy and gastric cannulas. | Life Sci. 1984 Jun 4;34(23):2233-8. doi: 10.1016/0024-3205(84)90210-8. | Gastrointestinal Tract | Mechanism |
| 30281151 | CLINICAL SIGNIFICANCE: Acupuncture targeted at the gastrointestinal tract of dogs was associated briefly with slowed gastric emptying and gastrointestinal transit time. | J Small Anim Pract. 2019 Jan;60(1):38-43. doi: 10.1111/jsap.12935. Epub 2018 Oct 3. | Gastrointestinal Tract | Mechanism |
| 26419631 | Some relevant experiments and study about D-IBS found that acupuncture could regulate central nervous system, immune system, endocrine system and GI tract, particularly the excitability of brain functional areas and dorsale medullae spinalis neurons. | BMC Complement Altern Med. 2015 Sep 29;15:340. doi: 10.1186/s12906-015-0863-5. | Immunity Gastrointestinal Tract Endocrinology | Mechanism |
| 34033703 | It is easily reproducible and, in addition to its effects on the digestive system, it is effective in multiple other system diseases, including the respiratory system . | Pediatr Pulmonol. 2021 Aug;56(8):2537-2545. doi: 10.1002/ppul.25466. Epub 2021 May 25. | Gastrointestinal Tract | Mechanism |
| 34033703 | In addition to improving general well-being, it is known to exert beneficial effects on diseases of the digestivee , motor , and immune systems . | Pediatr Pulmonol. 2021 Aug;56(8):2537-2545. doi: 10.1002/ppul.25466. Epub 2021 May 25. | Immunity Gastrointestinal Tract | Mechanism |
| 34564665 | Although these treatments are used alone or in combination, there are side effects such as gastrointestinal disorders, exacerbation of heart failure (NSAIDs), hypertension, restriction of use in diabetic patients (corticosteroids), digestive side effects, and renal and nervous system toxicity (Col). | Toxins (Basel). 2021 Sep 16;13(9):661. doi: 10.3390/toxins13090661. | Gastrointestinal Tract Toxic Side Effects Side Effects Kidney | Mechanism |
| 37435647 | Studies have confirmed that CRH in the central nucleus affects the motor function of the peripheral gastrointestinal tract through the autonomic nervous pathway. | J Neurophysiol. 2023 Aug 1;130(2):380-391. doi: 10.1152/jn.00156.2023. Epub 2023 Jul 12. | Gastrointestinal Tract Motor Function | Mechanism |
| 24828425 | ST36 is located at 3 cm below Dubi (stomach-35, ST35) and one finger's breadth before the anterior crest of the tibia, and is utilized as an acupoint for treating digestive system diseases (e.g., gastroplegia, functional dyspepsia, and intestinal obstruction). | PLoS One. 2014 May 14;9(5):e97488. doi: 10.1371/journal.pone.0097488. eCollection 2014. | Gastrointestinal Tract | Mechanism |
| 24908398 | In the GI tract, they act as pacemakers that generate and propagate slow waves, as mediators between the enteric nervous system and smooth muscle, and as stretch sensors. | BMC Complement Altern Med. 2014 Jun 7;14:186. doi: 10.1186/1472-6882-14-186. | Gastrointestinal Tract | Mechanism |
| 24908398 | Functioning ICC are essential for slow wave activity in the GI tract. | BMC Complement Altern Med. 2014 Jun 7;14:186. doi: 10.1186/1472-6882-14-186. | Gastrointestinal Tract | Mechanism |
| 24886495 | This point is associated with more than ten common diseases, including digestive, respiratory, circulatory, urinary and nervous disorders. | BMC Complement Altern Med. 2014 May 31;14:178. doi: 10.1186/1472-6882-14-178. | Gastrointestinal Tract Circulation | Mechanism |
| 28358020 | The digestive disturbances of body related to CAG course is believed to induce elevated creatine excretion into urine and further influence DMA concentration. | Sci Rep. 2017 Mar 30;7:45580. doi: 10.1038/srep45580. | Gastrointestinal Tract | Mechanism |
| 28358020 | The metabolic abnormality of butyrate in urine can be considered as an indicator that CAG pathology may also have negative effect on the microbiome of digestive system. | Sci Rep. 2017 Mar 30;7:45580. doi: 10.1038/srep45580. | Gastrointestinal Tract | Mechanism |
| 28358020 | The interaction of the nervous system with the digestive system has been understood by the discovery of the enteric nervous system (ENS) in the middle of the nineteenth century. | Sci Rep. 2017 Mar 30;7:45580. doi: 10.1038/srep45580. | Gastrointestinal Tract | Mechanism |
| 28358020 | Since then, remarkable progress has been made in comprehending the bidirectional crosstalk between the brain and the digestive system. | Sci Rep. 2017 Mar 30;7:45580. doi: 10.1038/srep45580. | Gastrointestinal Tract | Mechanism |
| 28358020 | Inflammation of the digestive system, chronic abdominal pain syndromes and psychosocial stressors have been associated with the alterations in brain-gut interactions. | Sci Rep. 2017 Mar 30;7:45580. doi: 10.1038/srep45580. | Gastrointestinal Tract | Mechanism |
| 32956833 | Additionally, some studies have shown that the modulation of SP binding to NK1R may be useful in the treatment of diseases, such as inflammatory conditions associated with the gastrointestinal tract, emesis, depression, cancer, and social anxiety disorder. | Brain Behav Immun. 2021 Jan;91:683-694. doi: 10.1016/j.bbi.2020.08.016. Epub 2020 Sep 18. | Gastrointestinal Tract Nausea and Vomiting Anxiety Depression | Mechanism |
| 30906450 | Chemotherapy-induced nausea and vomiting (CINV) as well as anorexia, which are important acute complications during anti-cancer chemotherapy, involve various neurotransmitters and metabolic peptides of the central nervous system (CNS) and GI tract. | Exp Ther Med. 2019 Apr;17(4):2587-2597. doi: 10.3892/etm.2019.7250. Epub 2019 Feb 7. | Gastrointestinal Tract Nausea and Vomiting | Mechanism |
| 34621320 | There is increasing evidence in support of the presence of abnormal central changes of FD patients in addition to the peripheral changes in gastrointestinal tract. | Evid Based Complement Alternat Med. 2021 Sep 14;2021:2771094. doi: 10.1155/2021/2771094. eCollection 2021. | Gastrointestinal Tract | Mechanism |
| 28806763 | However, latest research have found that the central activation of PPARγ or arachidonic acid contributes to obesity by direct regulation of indigestive behaviors or impairment of hypothalamic leptin signaling and hepatic energy homeostasis. | PLoS One. 2017 Aug 14;12(8):e0181948. doi: 10.1371/journal.pone.0181948. eCollection 2017. | Gastrointestinal Tract | Mechanism |
| 19531626 | Effects of acupuncture and moxibustion on the gastrointestinal tract have been studied more widely. | Evid Based Complement Alternat Med. 2011;2011:969231. doi: 10.1093/ecam/nep050. Epub 2010 Oct 20. | Gastrointestinal Tract | Mechanism |
| 19531626 | The effect of acupuncture and moxibustion on the gastrointestinal tract is one of its important functions. | Evid Based Complement Alternat Med. 2011;2011:969231. doi: 10.1093/ecam/nep050. Epub 2010 Oct 20. | Gastrointestinal Tract | Mechanism |
| 22461840 | For analysis of the effects of acupuncture on digestive function, rats and dogs have been used as an animal model; however, rats are not diurnal animals and have different sleep conditions from humans. | Evid Based Complement Alternat Med. 2012;2012:472982. doi: 10.1155/2012/472982. Epub 2012 Feb 16. | Gastrointestinal Tract | Mechanism |
| 24527041 | In traditional oriental medicine, one of the most commonly used acupuncture points used for gynecological, fertility, digestive, urinary, sexual, and emotional disorders is SP6, or spleen 6. | Evid Based Complement Alternat Med. 2014;2014:216503. doi: 10.1155/2014/216503. Epub 2014 Jan 9. | Gastrointestinal Tract Mood | Mechanism |
| 33062027 | For acupoints selection, studies show that ST36 can regulate multiple systems, such as the digestive system, immune system, and endocrine system. | Evid Based Complement Alternat Med. 2020 Sep 24;2020:8764507. doi: 10.1155/2020/8764507. eCollection 2020. | Immunity Gastrointestinal Tract Endocrinology | Mechanism |
| 25206727 | Physiological sensations from the gastrointestinal tract are transferred to the central nervous system via the vagus nerve allowing adjustment of gastrointestinal secretory and motor functions. | Neural Regen Res. 2013 Mar 25;8(9):802-8. doi: 10.3969/j.issn.1673-5374.2013.09.004. | Gastrointestinal Tract Motor Function | Mechanism |
| 25206727 | Neurons in the brainstem and hypothalamus control autonomic nerve function, including cardiovascular, gastrointestinal tract, respiratory tract, urogenital and muscle-skeletal activities. | Neural Regen Res. 2013 Mar 25;8(9):802-8. doi: 10.3969/j.issn.1673-5374.2013.09.004. | Gastrointestinal Tract Cardiovascular | Mechanism |
| 26561562 | Functional bowel disorders (FBD) are a set of gastrointestinal (GI) conditions with symptoms attributable to the mid or lower GI tract. | Acupunct Med. 2016 Jun;34(3):194-200. doi: 10.1136/acupmed-2015-010897. Epub 2015 Nov 11. | Gastrointestinal Tract | Mechanism |
| 26561562 | Preclinical experiments have shown that EA stimulation of points on the abdomen can influence sympathetic nerves to the GI tract, while points in the four limbs can influence parasympathetic nerves (in view of their segmental relationships), and increased parasympathetic:sympathetic balance will theoretically promote GI movement. | Acupunct Med. 2016 Jun;34(3):194-200. doi: 10.1136/acupmed-2015-010897. Epub 2015 Nov 11. | Gastrointestinal Tract | Mechanism |
| 26561562 | It has been estimated that 95% of serotonin in the body is within the digestive tract, of which 90% is in the enterochromaffin cells distributed throughout the gut mucosa and 10% is in the neurons. | Acupunct Med. 2016 Jun;34(3):194-200. doi: 10.1136/acupmed-2015-010897. Epub 2015 Nov 11. | Gastrointestinal Tract | Mechanism |
| 26561562 | An established model to measure transit through the upper GI tract of rats was used, because the measurement of colonic transit in rats is difficult due to the fluid reservoir function of the caecum during periods of intestinal hypersecretion. | Acupunct Med. 2016 Jun;34(3):194-200. doi: 10.1136/acupmed-2015-010897. Epub 2015 Nov 11. | Gastrointestinal Tract | Mechanism |
| 26561562 | GI transit (%) was expressed as the distance travelled by the charcoal relative to the total length of the small intestine, and the data were analysed using the equation , where x=travel distance of the charcoal in the GI tract. | Acupunct Med. 2016 Jun;34(3):194-200. doi: 10.1136/acupmed-2015-010897. Epub 2015 Nov 11. | Gastrointestinal Tract | Mechanism |
| 26561562 | The resulting peristaltic reflex is largely responsible for bolus movement from proximal to distal sites within the GI tract. | Acupunct Med. 2016 Jun;34(3):194-200. doi: 10.1136/acupmed-2015-010897. Epub 2015 Nov 11. | Gastrointestinal Tract | Mechanism |
| 26561562 | The positive effects of EA may be mediated by excitation of parasympathetic nerves supplying the GI tract, which may account for the higher levels of 5-HT in colonic tissue (although the exact mechanism of action is unknown). | Acupunct Med. 2016 Jun;34(3):194-200. doi: 10.1136/acupmed-2015-010897. Epub 2015 Nov 11. | Gastrointestinal Tract | Mechanism |
| 34757591 | It can facilitate weight control by regulating the nervous, endocrine, and digestive systems. | Mol Neurobiol. 2022 Jan;59(1):703-716. doi: 10.1007/s12035-021-02609-1. Epub 2021 Nov 10. | Gastrointestinal Tract Endocrinology | Mechanism |
| 18830456 | Many clinical studies focus on the effects of acupuncture on digestive disorders. | Evid Based Complement Alternat Med. 2008 Sep;5(3):251-6. doi: 10.1093/ecam/nem077. | Gastrointestinal Tract | Mechanism |
| 18830456 | Although much more clinical work has centered on the effects of acupuncture on the digestive tract than for other organs, far less work has been done on the mechanism of these effects. | Evid Based Complement Alternat Med. 2008 Sep;5(3):251-6. doi: 10.1093/ecam/nem077. | Gastrointestinal Tract | Mechanism |
| 18830456 | Japan has a long history of research on acupuncture for the digestive function. | Evid Based Complement Alternat Med. 2008 Sep;5(3):251-6. doi: 10.1093/ecam/nem077. | Gastrointestinal Tract | Mechanism |
| 27594888 | The digestive system is very vulnerable to the influence of CPS. | Evid Based Complement Alternat Med. 2016;2016:1935372. doi: 10.1155/2016/1935372. Epub 2016 Aug 3. | Gastrointestinal Tract | Mechanism |
| 27594888 | The interstitial cell of Cajal (ICC) exhibits a highly branched morphology and forms unique network in the gastrointestinal tract (GI). | Evid Based Complement Alternat Med. 2016;2016:1935372. doi: 10.1155/2016/1935372. Epub 2016 Aug 3. | Gastrointestinal Tract | Mechanism |
| 27594888 | CPS can cause various symptoms related to the digestive system. | Evid Based Complement Alternat Med. 2016;2016:1935372. doi: 10.1155/2016/1935372. Epub 2016 Aug 3. | Gastrointestinal Tract | Mechanism |
| 27594888 | FGID are digestive diseases with high morbidity rates, and CPS is a key pathogenic factor. | Evid Based Complement Alternat Med. 2016;2016:1935372. doi: 10.1155/2016/1935372. Epub 2016 Aug 3. | Gastrointestinal Tract | Mechanism |
| 37635258 | Five organs: Brain, Liver, Gastrointestinal tract, Lung, Kidney. | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Gastrointestinal Tract Kidney | Mechanism |
| 31889778 | In recent years, PD research has been focused on the gastrointestinal tract and the related ENS. | Saudi J Biol Sci. 2019 Dec;26(8):1948-1955. doi: 10.1016/j.sjbs.2019.07.003. Epub 2019 Jul 13. | Gastrointestinal Tract | Mechanism |
| 31889778 | Environmental factors may have an effect on the occurrence and progression of PD through the gastrointestinal tract (GI). | Saudi J Biol Sci. 2019 Dec;26(8):1948-1955. doi: 10.1016/j.sjbs.2019.07.003. Epub 2019 Jul 13. | Gastrointestinal Tract | Mechanism |
| 31889778 | hormones and neuropeptides, which may in turn affect the brain, as is the case for dopamine of which almost half of the total amount is produced in the gastrointestinal tract. | Saudi J Biol Sci. 2019 Dec;26(8):1948-1955. doi: 10.1016/j.sjbs.2019.07.003. Epub 2019 Jul 13. | Gastrointestinal Tract | Mechanism |







