- The advantages of acupuncture anesthesia in clinical practice
In clinical practice, acupuncture anesthesia presents a multitude of advantages, pivotal among these being Body System Protection. This technique supports the body's natural defenses, reducing the physiological stress often associated with surgical procedures. By modulating the body's response to pain, acupuncture anesthesia allows for a lower Dosage of Medication, significantly reducing the potential for drug-related side effects. Furthermore, this approach plays a crucial role in Emotion Regulation, helping patients maintain a calm and stable emotional state, which is essential for a positive surgical outcome. The impact of acupuncture on the nervous system not only aids in Pain Relief but also promotes Enhanced Recovery After Surgery. Patients tend to experience faster recuperation times, attributed to the holistic nature of this method. Additionally, acupuncture anesthesia is associated with a Lower Incidence of Side Effects compared to conventional anesthetics. Its ability to modulate and balance the body's responses makes it an invaluable tool in the realm of modern medicine, offering a safer, more patient-centered approach to pain management and recovery.
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Body System Protection
- Brain Protection
- Acupuncture anesthesia plays a vital role in brain surgeries, ensuring precise and safe anesthesia, reducing the risk of neurological complications, and supporting optimal cognitive function.
- Lung Protection
- Acupuncture anesthesia reduces post-operative lung complications, aiding in rapid lung function recovery, particularly beneficial for lung surgeries.
- Neuroprotection
- Acupuncture anesthesia is crucial for safeguarding the nervous system, reducing nerve injuries, and preventing the progression of neurological disorders.
- Kidney
- Acupuncture anesthesia alleviates stress on the kidneys, reducing the risk of kidney injury, particularly valuable in kidney surgeries.
- Gastrointestinal Tract
- Acupuncture anesthesia supports gastrointestinal health, reducing the risk of post-operative digestive issues, and ensuring a smoother recovery.
- Cardiovascular
- Acupuncture anesthesia eases the cardiovascular system's burden, reducing the risk of cardiovascular complications, especially in cardiac surgeries.
- Myocardium
- Acupuncture anesthesia aids in protecting the myocardium, minimizing adverse effects on heart muscle, ensuring cardiac health.
- Cognitive Function
- Through emotional stability and neuroprotection, acupuncture anesthesia helps preserve cognitive function, reducing the risk of post-operative cognitive impairment.
- Motor Function
- Acupuncture anesthesia improves motor function, aiding in post-operative mobility, and enhancing overall quality of life.
- Language Function
- Acupuncture anesthesia supports language function rehabilitation, assisting patients in regaining their communication skills.
- Learning and Memory Ability
- Acupuncture anesthesia, by reducing post-operative pain and emotional instability, enhances learning and memory ability, promoting a speedy recovery.
Acupuncture anesthesia for Body System Protection-Kidney
| PMID | Evidence | Source | Keyword | Type |
|---|---|---|---|---|
| 15810442 | The treatment based on syndrome differentiation, modification of prescription according to the symptoms, special prescription and simple recipe and acupuncture were employed in treating Yin-deficiency of the kidney, Yang-deficiency of the kidney, Yin and Yang-deficiency of the kidney, breakdown of the normal physiological coordination between the heart and the kidney, deficiency of liver-Yin and kidney-Yin, insufficiency of both the spleen and the kidney, deficiency of Qi and blood in the heart and spleen, stagnation of the liver-Qi and deficiency of the spleen, stagnation of the liver-Qi, phlegm stagnancy and the upward invasion of heat-phlegm. | Zhongguo Zhong Yao Za Zhi. 2005 Mar;30(6):414-8. | Kidney | Review |
| 16010643 | Acupuncture and kidney disease. | Adv Chronic Kidney Dis. 2005 Jul;12(3):282-91. doi: 10.1016/j.ackd.2005.04.002. | Kidney | Review |
| 16010643 | Acupuncture and acupuncture-like somatic nerve stimulation have been used in different kidney diseases and several complications related to them. | Adv Chronic Kidney Dis. 2005 Jul;12(3):282-91. doi: 10.1016/j.ackd.2005.04.002. | Kidney | Review |
| 16010643 | The effect of acupuncture techniques in some kidney diseases is reviewed on the basis of clinical reports as well as mechanisms that may possibly explain the beneficial effects mediated by acupressure/acupuncture. | Adv Chronic Kidney Dis. 2005 Jul;12(3):282-91. doi: 10.1016/j.ackd.2005.04.002. | Kidney | Review |
| 19719854 | Medline database was assessed using isolated and conjugated key words (Chinese Medicine, Kampo, Chinese Herbal, Calculi, Stone Disease, Kidney, Acupuncture, Herbal Medicine). | Int Braz J Urol. 2009 Jul-Aug;35(4):396-405. doi: 10.1590/s1677-55382009000400002. | Kidney | Review |
| 21796811 | Acupuncture for treating uremic pruritus in patients with end-stage renal disease: a systematic review. | J Pain Symptom Manage. 2010 Jul;40(1):117-25. doi: 10.1016/j.jpainsymman.2009.11.325. | Kidney | Review |
| 26311288 | RESULTS: Twenty-two full-text articles relevant to acupuncture treatment for radiation-induced xerostomia were included and a total of 48 acupuncture points were searched in the 5 ancient Chinese classic acupuncture works, in which the most commonly used points were Chengjiang (CV24), Shuigou (GV 26), Duiduan (GV 27), Jinjin (EX-HN 12), and Yuye (EX-HN 13) on head and neck, Sanjian (LI 3), Shangyang (LI 1), Shaoshang (LU 11), Shaoze (SI 1), Xialian (LI 8) on hand, Fuliu (KI 7), Dazhong (KI 4), Zuqiaoyin (GB 44), Taichong (LR 3), Zhaohai (KI 6) on foot, Burong (ST 19), Zhangmen (LR 13), Tiantu (CV 22), Qimen (LR 14) on abdomen, Feishu (BL 13), Danshu (BL 19), Xiaochaogshu (BL 27), Ganshu (BL 18) on back, Shenmen (TF 4), Shen (CO10, Kidney), Yidan (CO11, Pancreas) and Pi (CO13, Spleen) on ear. | Chin J Integr Med. 2016 Jul;22(7):549-54. doi: 10.1007/s11655-015-2145-y. Epub 2015 Aug 26. | Kidney | Review |
| 30286626 | Acupuncture Application in Chronic Kidney Disease and its Potential Mechanisms. | Am J Chin Med. 2018;46(6):1169-1185. doi: 10.1142/S0192415X18500611. | Kidney | Review |
| 30286626 | In patients with CKD, acupuncture improves renal function, reduces proteinuria, controls hypertension, corrects anemia, relieves pain, and controls many hemodialysis-related complications such as uremic pruritus, insomnia and fatigue. | Am J Chin Med. 2018;46(6):1169-1185. doi: 10.1142/S0192415X18500611. | Insomnia Kidney | Review |
| 32428127 | Effects of acupuncture in patients with chronic kidney disease: a systematic review. | Rev Bras Enferm. 2020;73(4):e20180784. doi: 10.1590/0034-7167-2018-0784. Epub 2020 May 18. | Kidney | Review |
| 32428127 | OBJECTIVES: to analyze the effects of acupuncture techniques in patients with chronic kidney disease. | Rev Bras Enferm. 2020;73(4):e20180784. doi: 10.1590/0034-7167-2018-0784. Epub 2020 May 18. | Kidney | Review |
| 32428127 | The following descriptors were used: Acupuncture AND Chronic Renal Insufficiency AND Clinical Trial. | Rev Bras Enferm. 2020;73(4):e20180784. doi: 10.1590/0034-7167-2018-0784. Epub 2020 May 18. | Kidney | Review |
| 35179436 | The most commonly used combination of acupuncture points (four of 36 studies) was shenmen, sympathetic, liver, lung, and kidney, which are called NADA protocol. | J Addict Dis. 2022 Jul-Sep;40(3):415-427. doi: 10.1080/10550887.2021.2016011. Epub 2022 Feb 18. | Kidney | Review |
| 37005855 | Acupuncture, clinical effect, kidney deficiency and phlegm stasis, and dredging governor vessel to revitalize mind were the hotspots of clinical research. | Zhongguo Zhong Yao Za Zhi. 2023 Mar;48(6):1673-1681. doi: 10.19540/j.cnki.cjcmm.20221206.501. | Kidney | Review |
| 35313481 | found that the analgesic effect of acupuncture in urolithiasis-driven renal colic pain relief was superior to that of diclofenac and acetaminophen after ten minutes, and there was no significant difference in the analgesic effect of the three types of therapy after 120 minutes. | Evid Based Complement Alternat Med. 2022 Mar 12;2022:1451342. doi: 10.1155/2022/1451342. eCollection 2022. | Analgesic Effect Pain Relief Kidney | Review |
| 24701237 | We found that the acupoint of Ren Meridian (RN) and Spleen Meridian of Foot-Taiyin (SP) is more predominately involved in the Acupuncture and Moxibustion treatment than that of Bladder Meridian (BL) and Kidney Meridian (KI). | Evid Based Complement Alternat Med. 2014;2014:146383. doi: 10.1155/2014/146383. Epub 2014 Feb 19. | Kidney | Review |
| 25097658 | These views suggest that antihypertensive effects of acupuncture may be mediated by antioxidant enzymes and anti-inflammatory effects, which could modulate the renal sympathetic nerve activity and nitric oxide levels, leading to decreased blood pressure. | Evid Based Complement Alternat Med. 2014;2014:483294. doi: 10.1155/2014/483294. Epub 2014 Jul 7. | Blood Pressure Kidney | Review |
| 30298094 | In rat model of renal failure- (RF-) induced hypertension, stimulation with acupuncture, and most significantly with EA, at ST36 and KI3, not only attenuated glomerulosclerosis and tubulointerstitial fibrosis, but corrected the decreases in RF-induced IGF-1 mRNA and protein levels, thus counteracting oxidative stress. | Evid Based Complement Alternat Med. 2018 Sep 12;2018:8107508. doi: 10.1155/2018/8107508. eCollection 2018. | Kidney | Review |
| 30984420 | Acupuncture can protect blood vessels and renal tubules by inhibiting Ang II and reducing Nox. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Kidney | Review |
| 30984420 | Acupuncture can also reduce the sympathetic excitability, improve renal function, and decrease 24-hour urinary protein in order to protect the kidney. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Kidney | Review |
| 31110553 | Meanwhile, the study exclusion criteria were as follows: (1) studies focusing on IBS-C, IBS-M, or IBS-U; (2) duplicate publications; (3) studies enrolling participants with severe enteric disease or who developed heart failure, renal failure, or a malignancy during the study period; (4) commentary, editorial, experience introduction, conference article, review, graduation thesis, or case report; (5) nonhuman or animal studies; (6) studies in which there were intervention measures in treatment group other than acupuncture and CHM; (7) the articles had no clear outcome indexes, or incomplete data; and (8) studies whose conclusions had conflicted with the original data. | Evid Based Complement Alternat Med. 2019 Apr 14;2019:7680963. doi: 10.1155/2019/7680963. eCollection 2019. | Kidney | Review |
| 32148660 | Since acupuncture is nonpharmacologically based, there are no concerns regarding dependence, addiction, tolerance, and neurological toxicity, nor will acupuncture increase the metabolic burdens of the liver and kidney, making acupuncture a potentially attractive therapy for treating POCD. | Oxid Med Cell Longev. 2020 Feb 13;2020:9641904. doi: 10.1155/2020/9641904. eCollection 2020. | Toxic Side Effects Kidney | Review |
| 32215037 | Acupuncture might be useful in reducing injuries induced by sepsis in cardiac, lung, kidney, liver, gastrointestinal tract, and immune system. | Evid Based Complement Alternat Med. 2020 Mar 7;2020:3620741. doi: 10.1155/2020/3620741. eCollection 2020. | Immunity Gastrointestinal Tract Kidney | Review |
| 32215037 | Effects of Acupuncture at ST36 Ameliorates Renal Injury in Experimental Sepsis | Evid Based Complement Alternat Med. 2020 Mar 7;2020:3620741. doi: 10.1155/2020/3620741. eCollection 2020. | Kidney | Review |
| 32215037 | It was reported that acupuncture at ST36 could protect kidneys from sepsis-induced injury by reducing renal MDA, renal inflammatory cytokines (inducible nitric oxide synthase (iNOS), nuclear factor κB (NF-κB), MPO, and tumor necrosis factor-α (TNF-α)), plasma levels of blood urea nitrogen (BUN), and creatinine (Cr), improving renal histopathology scores, upregulating renal SOD, and HO-1 protein expression. | Evid Based Complement Alternat Med. 2020 Mar 7;2020:3620741. doi: 10.1155/2020/3620741. eCollection 2020. | Kidney | Review |
| 32215037 | The present study indicated that acupuncture at ST36 could be useful in reducing sepsis-induced injuries in heat, lung, kidney, liver, gastrointestinal tract, and immune system. | Evid Based Complement Alternat Med. 2020 Mar 7;2020:3620741. doi: 10.1155/2020/3620741. eCollection 2020. | Immunity Gastrointestinal Tract Kidney | Review |
| 32523527 | Our previous study (Yang et al.,) indicated that renal sympathetic activation-induced upregulation of epinephrine, norepinephrine, and renin content, which were attenuated by acupuncture in SHRs. | Front Aging Neurosci. 2020 May 25;12:138. doi: 10.3389/fnagi.2020.00138. eCollection 2020. | Kidney | Review |
| 33757500 | Eye acupuncture is much less complicated compared to traditional body-acupuncture as it only employs 13 acupoints, namely lung, large intestine, kidney, bladder, upper jiao, liver, gallbladder, middle jiao, heart, small intestine, spleen, stomach, and lower jiao. | BMC Complement Med Ther. 2021 Mar 23;21(1):101. doi: 10.1186/s12906-021-03272-8. | Kidney | Review |
| 33868443 | Among the 14 studies, 6 mentioned no adverse reactions between the experimental group and the control group, and 3 mentioned adverse reactions: Yan acupuncture group: gastrointestinal reactions (2 cases), control group: liver function impairment (4 cases), renal function impairment (4 cases), routine blood abnormalities (2 cases), gastrointestinal reactions (6 cases), and hypersensitivity reactions (2 cases). | Evid Based Complement Alternat Med. 2021 Apr 2;2021:6694936. doi: 10.1155/2021/6694936. eCollection 2021. | Adverse Reactions Kidney | Review |
| 33896475 | There is a dearth of studies evaluating acupuncture as a pain reduction strategy in kidney disease populations. | Semin Nephrol. 2021 Jan;41(1):68-81. doi: 10.1016/j.semnephrol.2021.02.007. | Kidney | Review |
| 33936242 | Since the pathogenesis of POF is mostly related to liver, spleen, kidney, and blood essences, acupuncture and moxibustion therapy can dredge meridians, regulate qi and blood, balance yin and yang, and harmonize the functions of viscera. | Evid Based Complement Alternat Med. 2021 Apr 15;2021:6677767. doi: 10.1155/2021/6677767. eCollection 2021. | Kidney | Review |
| 33936242 | explored the clinical effect of body acupuncture combined with ear acupuncture in the treatment of kidney deficiency and liver depression POF; the total effective rate in the treatment group was 80%, which was superior to 66.67% in the control group. | Evid Based Complement Alternat Med. 2021 Apr 15;2021:6677767. doi: 10.1155/2021/6677767. eCollection 2021. | Depression Kidney | Review |
| 33936242 | treated 60 patients with POF of kidney deficiency and liver depression type by electroacupuncture combined with heat sensitive moxibustion, with a total effective rate of 93.3%. | Evid Based Complement Alternat Med. 2021 Apr 15;2021:6677767. doi: 10.1155/2021/6677767. eCollection 2021. | Depression Kidney | Review |
| 34013776 | Acupuncture was inserted on points in Kidney 3, Heart 3, Bladder 60, Liver 3, Large intestine, Pericardium 7, Governor Vessel 20, ear points Shen Men, and Tranquilizer. | Clin Rehabil. 2021 Nov;35(11):1518-1529. doi: 10.1177/02692155211014827. Epub 2021 May 20. | Kidney | Review |
| 34262271 | We found that most of the studies followed the above treatment ideas after carrying out the association analysis on the seven high-frequency selected acupoints: 1) The running course of the meridians where the seven acupoints are located are related to lung, kidney, spleen, and stomach at different angles, acupuncture on them can strengthen the related viscera. | Int J Chron Obstruct Pulmon Dis. 2021 Jul 7;16:2023-2037. doi: 10.2147/COPD.S313439. eCollection 2021. | Kidney | Review |
| 34262271 | In conclusion, we summarized the rules of acupoint selection for acupuncture on diaphragm dysfunction in COPD: (1) following the treatment idea of Traditional Chinese Medicine that invigorating spleen and benefiting lung, treating the manifestation and root cause of disease; (2) the main acupuncture sites are abdomen and back; (3) mostly choosing acupoints on the meridians related to lung, kidney, spleen, and stomach; (4) having the characteristics of combining local point selection with specific point selection (Figure 2). | Int J Chron Obstruct Pulmon Dis. 2021 Jul 7;16:2023-2037. doi: 10.2147/COPD.S313439. eCollection 2021. | Kidney | Review |
| 34335848 | Not only is acupuncture effective for complications related to HD, such as uremic symptoms, insomnia, and fatigue, but also it is able to improve renal function, proteinuria, BP, anemia, and pain in CKD patients. | Evid Based Complement Alternat Med. 2021 Jul 13;2021:9953986. doi: 10.1155/2021/9953986. eCollection 2021. | Insomnia Blood Pressure Kidney | Review |
| 34630605 | According to basic theories of traditional Chinese medicine, acupuncture can promote Qi transformation of the kidney and bladder and restore bladder function. | Evid Based Complement Alternat Med. 2021 Sep 29;2021:2500282. doi: 10.1155/2021/2500282. eCollection 2021. | Kidney | Review |
| 34671411 | The underlying molecular mechanisms of acupuncture involved in the present review for hypertension are summarized as follows: (1) inhibition of inflammatory factors including tumor necrosis factor-α (TNF-α), interleukin-6, and C-reactive protein, as well as inflammation-related genes, through toll-like receptor 4 in the PVN; (2) reduction of oxidative stress reactions by inhibiting nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity by downregulation of p38 mitogen-activated protein kinases and extracellular signal-regulated protein kinase 1/2; (3) inhibition of AngII activity in the plasma, myocardium, thoracic aorta, rostral ventrolateral medulla, kidney, etc. | Evid Based Complement Alternat Med. 2021 Oct 11;2021:8171636. doi: 10.1155/2021/8171636. eCollection 2021. | Stress Response Kidney Myocardium | Review |
| 34675729 | Acupuncture also does not increase the metabolic burden of the liver and kidney. | Nat Sci Sleep. 2021 Oct 12;13:1823-1863. doi: 10.2147/NSS.S332474. eCollection 2021. | Kidney | Review |
| 35002950 | The TCM syndrome types, subjective symptoms, objective indicators, Chinese herbal medicine, acupuncture points, and TCM prescriptions for T2DM were compiled based on invigorating the kidney and Qi, nourishing Yin, and strengthening the spleen. | Front Endocrinol (Lausanne). 2021 Dec 23;12:728032. doi: 10.3389/fendo.2021.728032. eCollection 2021. | Kidney | Review |
| 35002950 | The above acupuncture points are primarily distributed on the Stomach Meridian of Foot-Yangming, Spleen Meridian of Foot-Taiyin, Kidney Meridian of Foot-Shaoyin, and Bladder Meridian of Foot-Taiyang. | Front Endocrinol (Lausanne). 2021 Dec 23;12:728032. doi: 10.3389/fendo.2021.728032. eCollection 2021. | Kidney | Review |
| 35002950 | As suggested in this study, the main treatment theories for T2DM in TCM are to invigorate the kidney and promote blood circulation, invigorate Qi, and dissipate blood stasis, which is achieved by taking TCM medicine or external treatments (e.g., acupuncture and moxibustion). | Front Endocrinol (Lausanne). 2021 Dec 23;12:728032. doi: 10.3389/fendo.2021.728032. eCollection 2021. | Kidney Circulation | Review |
| 35241146 | a XingNaoKaiQiao (XNKQ) protocol, an acupuncture method for ischemic stroke treatment, includeing stimulating the main points to induce resuscitation and to tonify the liver and kidney and the supplementary points to dredge the meridians. | Stem Cell Res Ther. 2022 Mar 3;13(1):87. doi: 10.1186/s13287-022-02761-y. | Kidney | Review |
| 35313481 | found that the analgesic effect of acupuncture in urolithiasis-driven renal colic pain relief was superior to that of diclofenac and acetaminophen after ten minutes, and there was no significant difference in the analgesic effect of the three types of therapy after 120 minutes. | Evid Based Complement Alternat Med. 2022 Mar 12;2022:1451342. doi: 10.1155/2022/1451342. eCollection 2022. | Analgesic Effect Pain Relief Kidney | Review |
| 35380733 | Reviews included trials of acupuncture in the treatment of various acute pain conditions and injuries in adults and children in the ED, including acute LBP, acute neck pain, and acute ankle sprain; other musculoskeletal pain conditions, fractures, and nonpenetrating injuries; acute abdominal pain, appendicitis pain, renal colic, acute headache and migraine, acute dental pain, and acute pharyngitis. | Pain Med. 2022 Aug 31;23(9):1582-1612. doi: 10.1093/pm/pnac056. | Kidney | Review |
| 35832526 | Efficacy and Safety of Acupuncture in Renal Colic Caused by Urinary Calculi in Adults: A Systematic Review and Meta-Analysis | Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. | Kidney | Review |
| 35832526 | At present, there is no systematic evaluation of the efficacy and safety of manual acupuncture in the treatment of acute renal colic caused by urinary calculi in adults. | Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. | Kidney | Review |
| 35832526 | To evaluate the efficacy and safety of manual acupuncture in the treatment of acute renal colic caused by urinary calculi in adults. | Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. | Kidney | Review |
| 35832526 | Only randomized controlled trials (RCTs) of manual acupuncture as the therapy for acute renal colic caused by urinary calculi in adults were included, whether or not the blind method is used. | Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. | Kidney | Review |
| 35832526 | In the course of manual acupuncture treatment of acute renal colic caused by urinary calculi in adults, available evidence suggests that manual acupuncture is as effective as positive treatment drugs, either as a monotherapy or as an adjunctive therapy, with the advantage of acupuncture being its rapid onset of action. | Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. | Kidney | Review |
| 35832526 | Studies in recent years have shown that the acupuncture treatment of acute renal colic caused by urinary calculi has rapid pain relief, reliable curative effect, and no toxic side effects, but the sample sizes of these trials were small, and their conclusions were seen as overly positive. | Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. | Pain Relief Toxic Side Effects Side Effects Kidney | Review |
| 35832526 | At present, over 80 systematic reviews have been conducted to assess the role of acupuncture and related therapies in the relief of pain; however, the results of these systematic reviews are far from unanimous, and there is no systematic evaluation of the efficacy and safety of manual acupuncture in the treatment of acute renal colic caused by urinary calculi in adults. | Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. | Pain Relief Kidney | Review |
| 35832526 | The purpose of this study is to systematically evaluate the efficacy and safety of manual acupuncture in the treatment of acute renal colic caused by urinary calculi in adults and to provide more evidence for clinical application. | Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. | Kidney | Review |
| 35832526 | We searched the database of Cochrane Library, EMBASE, PubMed, CNKI, Wanfang Medical Database, SinoMed, and VIP from the establishment of the database to February 9, 2022 and collected randomized controlled trials on manual acupuncture treatment of acute renal colic caused by urinary calculi in adults. | Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. | Kidney | Review |
| 35832526 | The search strategies include (Renal Colic OR Colic, Renal OR Colics Renal OR Renal Colics OR Acute Renal Colic OR Acute Renal Colics OR Colic, Acute Renal OR Colics, Acute Renal OR Renal Colic, Acute OR Renal Colics, Acute OR Ureteral Colic OR Colic, Ureteral OR Colics, Ureteral OR Ureteral Colics) AND (Acupuncture OR Pharmacopuncture OR Acupuncture Therapy OR Therapy, Acupuncture OR Acupuncture Treatment OR Acupuncture Treatments OR Treatment, Acupuncture OR Pharmacoacupuncture Treatment OR Treatment, Pharmacoacupuncture OR Pharmacoacupuncture Therapy OR Therapy, Pharmacoacupuncture OR Acupuncture Points OR Acupuncture Point OR Point, Acupuncture OR Points, Acupuncture OR Acupoints OR Acupoint OR Acupuncture Analgesia OR Analgesia, Acupuncture OR Acupuncture Anesthesia OR Anesthesia, Acupuncture). | Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. | Kidney | Review |
| 35832526 | Only RCTs of manual acupuncture as the therapy for acute renal colic caused by urinary calculi in adults were included, whether or not the blind method is used. | Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. | Kidney | Review |
| 35832526 | Low-certainty evidence indicates that there was no statistical difference between the response rate of relieving renal colic by acupuncture as an adjuvant therapy group and the control group. | Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. | Kidney | Review |
| 35832526 | We aimed to evaluate the efficacy and safety of manual acupuncture in the treatment of acute renal colic caused by urinary calculi in adults. | Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. | Kidney | Review |
| 35832526 | Based on the current level of evidence, in the treatment of renal colic, we believe that there is insufficient evidence to support that acupuncture as a monotherapy or acupuncture as an adjuvant therapy is superior in terms of overall efficacy compared with drug alone. | Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. | Kidney | Review |
| 35832526 | For the treatment of adult renal colic, available evidence suggests that manual acupuncture is as effective as positive treatment drugs, either as a monotherapy or as an adjunctive therapy, with the advantage of acupuncture being its rapid onset of action. | Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. | Kidney | Review |
| 36148057 | Several clinical trials have proven that acupuncture therapies [including abdominal acupuncture, auricular acupuncture, electroacupuncture, and transcutaneous electrical acupoint stimulation ] have therapeutic effects on multiple types of hypertension [prehypertension and mild hypertension, renal failure-induced hypertension, hypertension in stroke patients, and hypertension in perimenopausal women . | Front Cardiovasc Med. 2022 Sep 6;9:920491. doi: 10.3389/fcvm.2022.920491. eCollection 2022. | Kidney | Review |
| 36148057 | In addition, acupuncture inhibits the sympathetic nervous system via the regulation of renal sympathetic and ss-adrenergic receptor expression. | Front Cardiovasc Med. 2022 Sep 6;9:920491. doi: 10.3389/fcvm.2022.920491. eCollection 2022. | Kidney | Review |
| 36530891 | Acupuncture, auricular acupressure, and the combination of acupoint injection and acupoint massage seem to be effective in improving uremic pruritus in patients with chronic kidney disease. | Front Med (Lausanne). 2022 Dec 1;9:1036072. doi: 10.3389/fmed.2022.1036072. eCollection 2022. | Kidney | Review |
| 36530891 | The search string used was based on PubMed medical subject headings and Embase subject headings (Emtree): (chronic kidney disease OR kidney injury OR kidney failure OR chronic renal failure OR end-stage renal disease OR end stage renal disease OR dialysis OR hemodialysis OR peritoneal dialysis) OR (uremic OR uremia OR uremias) AND (pruritus OR itch OR xerosis OR skin problems OR skin disorders) AND (acupuncture OR acupressure OR Shiatsu OR Zhi Ya OR Chih Ya OR Shiatzu OR auricular acupuncture OR ear acupuncture OR auricular acupressure OR ear acupressure OR auricular therapy OR auriculotherapy OR auricular needle OR otopoint OR otoneedle OR auriculoacupuncture OR otopuncture OR acupressure point OR acupoints OR Tui Na). | Front Med (Lausanne). 2022 Dec 1;9:1036072. doi: 10.3389/fmed.2022.1036072. eCollection 2022. | Kidney | Review |
| 36570846 | It has also been reported that auricular electrical stimulation, acupuncture, and electroacupuncture at ST36 reduce serum concentrations of the inflammatory cytokines TNF-, IL-1, and IL-6 and improve renal and lung injury in sepsis-affected rodents. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Kidney | Review |
| 36570846 | However, the potential mechanisms by which acupuncture regulates other visceral functions in the lungs, liver, and kidney are not known, which represents a limitation of the present study, and which requires further study and analysis. | Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. | Kidney | Review |
| 36698826 | Clinical efficacy of acupuncture for pain relief from renal colic: A meta-analysis and trial sequence analysis | Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. | Pain Relief Kidney | Review |
| 36698826 | This meta-analysis aimed at investigating the efficacy of acupuncture for relieving renal colic and reducing the risk of analgesic-related complications. | Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. | Kidney | Review |
| 36698826 | Compared with conventional analgesic-based interventions, acupuncture can more efficiently relieve renal colic with fewer adverse effects. | Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. | Adverse Reactions Kidney | Review |
| 36698826 | Consistently, acupuncture is gaining popularity as an adjunctive therapy in the treatment of renal colic and for patients after extracorporeal shock wave lithotripsy (ESWL). | Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. | Kidney | Review |
| 36698826 | analgesics for treating renal colic has been investigated in a recent systematic review, that report included studies focusing on conventional acupuncture as a monotherapy in a relatively small patient population so that the scope of acupuncture may be limited and the robustness of evidence may be impaired. | Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. | Kidney | Review |
| 36698826 | Therefore, through incorporating the evidence from the latest randomized controlled trials (RCTs), the current meta-analysis attempted to elucidate the therapeutic efficacy of acupuncture compared to that of analgesics against renal colic with different indices for outcome assessment at different time points. | Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. | Kidney | Review |
| 36698826 | Studies that assessed the analgesic efficacy of acupuncture against renal colic were considered eligible. | Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. | Kidney | Review |
| 36698826 | RCTs were selected based on the following criteria and predefined PICO (i.e., population, interventions, comparison, and outcome) framework: (a) Patient population: adult patients (â¥18 years) with renal colic as the major clinical symptom; (b) Intervention: the use of acupuncture regardless of its location or type; (c) Comparison: the use of analgesics (e.g., NSAIDS, opioids) and antispasmodics through conventional routes, namely oral, intramuscular, or intravenous administration; (d) Outcomes: available information about response rate and results of pain severity assessment with visual analog scale (VAS) or any other numerical scales. | Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. | Kidney | Review |
| 36698826 | The main finding of the current systematic review of 13 RCTs was the higher response rate of acupuncture compared to conventional interventions in patients with renal colic. | Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. | Kidney | Review |
| 36698826 | In fact, the previous meta-analysis demonstrated no improvement in response rate when a combined regimen of acupuncture and conventional medications was compared with conventional medical treatments among patients with renal colic. | Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. | Kidney | Review |
| 36698826 | Taking into account the comparatively fast onset as well as a long duration of action, acupuncture may be considered an alternative analgesic strategy in the treatment of acute renal colic. | Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. | Kidney | Review |
| 36698826 | The strengths of this study could be summarized as follows: (1) In addition to the study of the efficacy of conventional manual acupuncture for treating renal colic as in a recent meta-analysis, the present investigation included other acupuncture techniques (e.g., electro-acupuncture) in our analysis that involved more than a thousand participants; (2) Compared with the previous meta-analytic study, we also examined the robustness of evidence and heterogeneity by using TSA and meta-regression analysis, respectively; and (3) In contrast to the results of the prior meta-analysis that demonstrated a large publication bias, a low level of publication bias in this study may reflect a better quality of evidence. | Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. | Kidney | Review |
| 36698826 | Objective outcome indicators, such as time to complete pain relief, episodes of renal colic during treatment and adverse effects as well as circulating prostaglandin E2 concentration, may be included in future studies to provide more accurate information for elucidating the beneficial effects of acupuncture in this clinical setting. | Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. | Pain Relief Adverse Reactions Kidney Circulation | Review |
| 36698826 | The results of the current meta-analysis showed that the clinical efficacy of acupuncture for renal colic was superior to that of conventional analgesics with a rapid onset of analgesia and relatively few adverse effects. | Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. | Adverse Reactions Kidney | Review |
| 36845424 | Acupuncture, massage, or herbal fumigation should consider tonifying Yin deficiency via the acupoints on Yin meridians (such as spleen, liver, and kidney meridians) based on the dialectical diagnosis. | Front Neurosci. 2023 Feb 8;17:1097477. doi: 10.3389/fnins.2023.1097477. eCollection 2023. | Kidney | Review |
| 36930068 | Qian Lala et al designed a randomized controlled trial using Jiaotai Pill combined with acupuncture for Annmian, Xin Yu, Kidney Yu, Shen Men, and Zhao Hai. | Medicine (Baltimore). 2023 Mar 17;102(11):e33213. doi: 10.1097/MD.0000000000033213. | Kidney | Review |
| 37046882 | In particular, three studies (37.5%) used the National Acupuncture Detoxification Association protocol to stimulate the bilateral sympathetic, Shenmen, kidney, liver, and lung auricular points. | Healthcare (Basel). 2023 Mar 27;11(7):955. doi: 10.3390/healthcare11070955. | Kidney | Review |
| 37046882 | Four studies used auricular acupuncture points, and three of them used bilateral sympathetic, Shenmen, kidney, liver, and lung acupuncture points of the National Acupuncture Detoxification Association (NADA) protocol. | Healthcare (Basel). 2023 Mar 27;11(7):955. doi: 10.3390/healthcare11070955. | Kidney | Review |
| 37046882 | Among the studies included in this review, auricular acupuncture was performed using the NADA protocol and auricular acupuncture using other protocols (liver, heart, spleen, kidney, Shenmen, and subcortex points); however, the effects of the two auricular acupuncture strategies could not be compared. | Healthcare (Basel). 2023 Mar 27;11(7):955. doi: 10.3390/healthcare11070955. | Kidney | Review |
| 37168651 | Bioelectrical technology, as an effective treatment for RH, has developed rapidly in recent years and mainly includes renal sympathetic denervation, carotid baroreflex activation therapy, Traditional Chinese Medicine electroacupuncture and transcutaneous electrical nerve stimulation (TENS). | Biomed Rep. 2023 Apr 18;18(6):38. doi: 10.3892/br.2023.1621. eCollection 2023 Jun. | Kidney | Review |
| 37168651 | Furthermore, growing evidence has been provided for bio-electric techniques in the treatment of hypertension, with results seen in the fields of renal sympathetic denervation (RDN), carotid baroreflex activation therapy (CBAT) and Chinese medicine electroacupuncture for the lowering of BP. | Biomed Rep. 2023 Apr 18;18(6):38. doi: 10.3892/br.2023.1621. eCollection 2023 Jun. | Blood Pressure Kidney | Review |
| 37168651 | Tjen-A-Looi et al indicated that acupuncture may cause a decrease in sympathetic excitability in the RVLM region by modulating the projections from the paraventricular nucleus to the RVLM and the expression of opioid receptors and γ-aminobutyric acid receptors, which in turn causes a decrease in BP, and a significant decrease in renal vascular resistance was found by Doppler ultrasound measurement of renal artery vascular resistance after at least three sessions of moxibustion treatment at bilateral dorsal acupoints. | Biomed Rep. 2023 Apr 18;18(6):38. doi: 10.3892/br.2023.1621. eCollection 2023 Jun. | Blood Pressure Kidney | Review |
| 37260441 | Professor Shi treated PCOS women with obesity and infertility by acupuncture from the perspective of spleen and kidney function. | Front Endocrinol (Lausanne). 2023 May 16;14:956772. doi: 10.3389/fendo.2023.956772. eCollection 2023. | Kidney | Review |
| 37260441 | Combined treatment of acupuncture, moxibustion, and drugs can effectively improve endometrial receptivity and uterine artery blood flow in PCOS patients with kidney deficiency and blood stasis and increase pregnancy rate. | Front Endocrinol (Lausanne). 2023 May 16;14:956772. doi: 10.3389/fendo.2023.956772. eCollection 2023. | Kidney Blood Flow | Review |
| 37289799 | Likewise, common ear acupoints of importance in the studies using ear acupressure or ear acupuncture included the subcortex, sympathetic, liver, and kidney. | PLoS One. 2023 Jun 8;18(6):e0286671. doi: 10.1371/journal.pone.0286671. eCollection 2023. | Kidney | Review |
| 37332744 | Acupuncture has long been used as a mode of analgesia that improves lower urinary tract symptoms through inducing ureteral smooth muscle relaxation, thereby achieving renal colic pain relief. | Front Med (Lausanne). 2023 Jun 2;10:1114485. doi: 10.3389/fmed.2023.1114485. eCollection 2023. | Pain Relief Kidney | Review |
| 37332744 | Moreover, the description of a higher incidence of recurrent renal colic as the major adverse event among the recruited individuals in the two studies that enrolled control subjects with no medication may further imply the efficacy of acupuncture for pain relief in patients receiving ESWL. | Front Med (Lausanne). 2023 Jun 2;10:1114485. doi: 10.3389/fmed.2023.1114485. eCollection 2023. | Pain Relief Kidney | Review |
| 37505150 | The study found that Sangzhen Yangshen Formula plus acupuncture combined with levodopa and benserazide tablets could improve the gait balance and walking ability of PD with deficiency of liver-yin and kidney-yin syndrome, and improve the quality of life, which may be related to alleviating nerve inflammatory reaction and promoting nerve repair. | Medicine (Baltimore). 2023 Jul 28;102(30):e34278. doi: 10.1097/MD.0000000000034278. | Kidney | Review |
| 37505150 | To study the effect of Dihuang Ziyin Bushen Prescription combined with acupuncture on PD patients with liver and kidney deficiency syndrome, which can not only effectively alleviate the symptoms of liver and kidney deficiency, but also resist oxidative stress and reduce inflammatory reaction, and is conducive to improving the quality of life of patients (Table 1). | Medicine (Baltimore). 2023 Jul 28;102(30):e34278. doi: 10.1097/MD.0000000000034278. | Kidney | Review |
| 37675019 | Mechanisms underlying acupuncture therapy in chronic kidney disease: A narrative overview of preclinical studies and clinical trials | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Kidney | Review |
| 37675019 | Few studies explored the correlation between acupuncture and renal pathological diagnosis. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Kidney | Review |
| 37675019 | This review help provide a theoretical basis for further research regarding the influence of acupuncture on renal pathology in patients with CKD, as well as the differences between specific therapeutic mechanisms of acupuncture in different renal pathological diagnosis. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Kidney | Review |
| 37675019 | Meanwhile, some studies also focused on the effects of acupuncture on hemodynamics and renal interstitial fibrosis. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Hemodynamics Kidney | Review |
| 37675019 | Mechanisms Underlying the Effects of Acupuncture Therapy in Chronic Kidney Disease. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Kidney | Review |
| 37675019 | The gray grids are the known possible main mechanism/target/downstream product of acupuncture in treating chronic kidney disease. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Kidney | Review |
| 37675019 | A study on rats with DN showed that electroacupuncture (EA) increased the levels of FOXO1 and PGC-1α in kidney tissue, thus improving renal function. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Kidney | Review |
| 37675019 | A study on rats with DN showed that acupuncture and moxibustion have synergistic effects on antioxidant stress, which may be related to their function in downregulating the expression of MDA and upregulating the expressions of NOS and SOD in the kidney. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Kidney | Review |
| 37675019 | Acupuncture has been shown to have certain clinical effects on renal hypertension. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Kidney | Review |
| 37675019 | Therefore, it is believed that the AT1R-ET-1-ETAR pathway may be a target for acupuncture treatment of renal hypertension. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Kidney | Review |
| 37675019 | Moreover, acupuncture reduced local renal sympathetic nerve activity by inhibiting the extracellular regulated protein kinase ½-MAPK pathway to lower blood pressure. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Blood Pressure Kidney | Review |
| 37675019 | Another study also verified the relationship between acupuncture and renal sympathetic activity. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Kidney | Review |
| 37675019 | Additionally, the possibility of acupuncture being able to directly affect the process of renal fibrosis in hypertensive rats has also been suggested. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Kidney | Review |
| 37675019 | Acupuncture can delay the aging of the kidney tissue by suppressing oxidative stress and reducing apoptosis. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Kidney | Review |
| 37675019 | An experiment suggested that the apoptosis rate of renal cells and the levels of hydrogen peroxide and malondialdehyde decreased after acupuncture in adult rats. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Kidney | Review |
| 37675019 | The evidence of this review reveals several beneficial effects of acupuncture on CKD and ESRD-related symptoms, and a summary of studies on acupuncture therapy in chronic renal injury, renal physiological function and ESRD-related symptoms is presented in Table 1 . | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Kidney | Review |
| 37675019 | In general, acupuncture has the potential to become a new, simple, safe, and inexpensive treatment modality that can be used to treat CKD, slow the progress of renal dysfunction, and improve patient symptoms. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Kidney | Review |
| 37675019 | This could prove conducive to understanding the potential mechanisms involved in different renal pathological diagnosis as well as the impact that acupuncture may have on them. | Front Nephrol. 2022 Nov 9;2:1006506. doi: 10.3389/fneph.2022.1006506. eCollection 2022. | Kidney | Review |
| 37998449 | Considering the various acupuncture approaches, auricular acupuncture has been the most commonly used approach, with the Shenmen and Kidney points being frequently targeted. | Healthcare (Basel). 2023 Nov 14;11(22):2957. doi: 10.3390/healthcare11222957. | Kidney | Review |
| 38046583 | In contrast, acupuncture has the advantages of high safety and no toxic side effects and is more easily accepted by patients with heart, liver, and kidney damage. | Front Neurol. 2023 Nov 17;14:1268626. doi: 10.3389/fneur.2023.1268626. eCollection 2023. | Toxic Side Effects Side Effects Kidney | Review |
| 38165870 | As a non-pharmacological treatment, acupuncture rarely causes adverse effects such as gastrointestinal discomfort, liver function damage, and kidney function damage because it does not involve pharmacological metabolism and other effects. | PLoS One. 2024 Jan 2;19(1):e0291685. doi: 10.1371/journal.pone.0291685. eCollection 2024. | Adverse Reactions Kidney | Review |
| 38189090 | Therapeutic effects of acupuncture therapy for kidney function and common symptoms in patients with chronic kidney disease: a systematic review and meta-analysis | Ren Fail. 2024 Dec;46(1):2301504. doi: 10.1080/0886022X.2023.2301504. Epub 2024 Jan 8. | Kidney | Review |
| 38189090 | Purpose: The number of clinical reports of acupuncture therapy in chronic kidney disease (CKD) is gradually increasing. | Ren Fail. 2024 Dec;46(1):2301504. doi: 10.1080/0886022X.2023.2301504. Epub 2024 Jan 8. | Kidney | Review |
| 38189090 | This systematic review and meta-analysis aim to examine the therapeutic role of acupuncture therapy in kidney function and common symptoms in CKD patients. | Ren Fail. 2024 Dec;46(1):2301504. doi: 10.1080/0886022X.2023.2301504. Epub 2024 Jan 8. | Kidney | Review |
| 38189090 | Conclusions: Acupuncture is an effective and safe treatment for improving kidney function and relieving pruritic symptoms in patients with CKD, but the very low evidence may limit this conclusion. | Ren Fail. 2024 Dec;46(1):2301504. doi: 10.1080/0886022X.2023.2301504. Epub 2024 Jan 8. | Kidney | Review |
| 38189090 | Acupuncture therapy may improve kidney function and relieve pruritus symptoms in CKD patients, but both are very low evidence. | Ren Fail. 2024 Dec;46(1):2301504. doi: 10.1080/0886022X.2023.2301504. Epub 2024 Jan 8. | Kidney | Review |
| 38189090 | Eligibility criteria were based on PICOS (Population, Intervention, Comparator, Outcome, Study design) elements developed by potential randomized controlled trials (RCTs) should include (1) adult patients (age â¥18) diagnosed as CKD, including pre-dialysis, peritoneal dialysis, hemodialysis, kidney transplant recipients, (2) participants in the intervention group receiving acupuncture treatment, (3) participants in the control or placebo group receiving usual care or sham acupuncture, (4) outcomes of interest included kidney function, included serum creatinine (Scr) and blood urea nitrogen (BUN), and CKD-related common symptoms. | Ren Fail. 2024 Dec;46(1):2301504. doi: 10.1080/0886022X.2023.2301504. Epub 2024 Jan 8. | Kidney | Review |
| 38189090 | The results of this systematic review and meta-analysis, which included 24 RCTs involving 1494 patients with CKD, showed an association between acupuncture and improvement in kidney function and a reduction in pruritus in patients with CKD compared with sham acupuncture or conventional treatment. | Ren Fail. 2024 Dec;46(1):2301504. doi: 10.1080/0886022X.2023.2301504. Epub 2024 Jan 8. | Kidney | Review |
| 38189090 | Second, regulating the immune system: acupuncture is believed to regulate immune system function and reduce inflammatory response in CKD, which may help reduce further damage to kidney tissues and promote repair and regeneration processes. | Ren Fail. 2024 Dec;46(1):2301504. doi: 10.1080/0886022X.2023.2301504. Epub 2024 Jan 8. | Immunity Kidney | Review |
| 38189090 | Since uremic pruritus is closely related to kidney function, acupuncture treatment improves kidney function and reduces pruritus to some extent. | Ren Fail. 2024 Dec;46(1):2301504. doi: 10.1080/0886022X.2023.2301504. Epub 2024 Jan 8. | Kidney | Review |
| 38189090 | Based on the above findings, future studies could include more populations of different races/ethnicities from other countries to increase the generalizability; a larger, statistically powerful multicenter, long-follow-up RCT study to further validate the efficacy of acupuncture on the prognosis of CKD; using standardized acupuncture protocols, as well as a consistent, validated renal function/symptom measure, would increase the consistency of future trials; a more rigorous design and clearer RCT reporting following the Consolidated Standards of Reporting Trials (CONSORT) guidelines is necessary; in hemodialysis patients, it would make sense to conduct crossover trials to assess the effects of different acupoint prescriptions and times (pre-, intra-, post-dialysis). | Ren Fail. 2024 Dec;46(1):2301504. doi: 10.1080/0886022X.2023.2301504. Epub 2024 Jan 8. | Kidney | Review |
| 38189090 | This systematic review and meta-analysis demonstrated that acupuncture treatment was effective in improving renal function and decreasing pruritus in patients with CKD compared with sham acupuncture and/or no acupuncture, with a GRADE level of evidence of very low. | Ren Fail. 2024 Dec;46(1):2301504. doi: 10.1080/0886022X.2023.2301504. Epub 2024 Jan 8. | Kidney | Review |
| 6660201 | Electrical skin resistance increased an average of 15 percent in bladder, kidney, liver, stomach, gall bladder meridians, and decreased an average of 18 percent in lung, small intestine, heart, spleen-pancreas, heart constrictor, triple heater, large intestine meridians. | Am J Chin Med. 1983;11(1-4):130-6. doi: 10.1142/S0192415X83000215. | Kidney | Clinic |
| 6660201 | When comparing the skin resistance values with those under acupuncture anesthesia during ophthalmic surgery, the skin resistance value under acupuncture anesthesia exhibited a marked decrease in all meridians (average 23 percent decrease) except the kidney meridian. | Am J Chin Med. 1983;11(1-4):130-6. doi: 10.1142/S0192415X83000215. | Kidney | Clinic |
| 6660201 | On the other hand, the skin resistance under local anesthesia was only a 7.4 percent decrease in all meridians except the kidney meridian. | Am J Chin Med. 1983;11(1-4):130-6. doi: 10.1142/S0192415X83000215. | Kidney | Clinic |
| 22712373 | There were 11 males and 19 females in the AA group,with an average age of (60.93 +/- 5.90) years; the patients were treated with auricular acupuncture on the point of Shenmen, Subcortex, Kidney and hip joint for four times a week. | Zhongguo Gu Shang. 2012 Mar;25(3):220-3. | Kidney | Clinic |
| 22459647 | Between-group comparison analysis of hepatic and renal function and severe adverse reactions all showed no significant difference between the three groups. | Acupunct Med. 2012 Jun;30(2):78-84. doi: 10.1136/acupmed-2011-010095. Epub 2012 Mar 29. | Adverse Reactions Kidney | Clinic |
| 24621826 | After obtaining Ethics Committee approval and written informed consent, 80 patients with American Society of Anesthesiologists physical status (ASA) I or II were recruited and underwent elective surgery lasting more than 3 h but less than 4 h. Exclusion criteria included: previous history of acupuncture or emulsion allergies, ASA physical status >II, patients below 18 years or above 75 years, having a body mass index greater than 30, and those patients who had received long-term hormone therapy, had a psychiatric or liver and kidney dysfunction history, or who had received opioids in the preceding month. | Med Sci Monit. 2014 Mar 12;20:406-12. doi: 10.12659/MSM.890111. | Kidney | Clinic |
| 25152761 | The primary origin of the pain generated in lithotripsy is due to the shock wave passing through the skin, which induces peripheral pain and this is followed by organ pain induced by effects of the focused shock wave on the area around the kidney where there are nerves distributed in the capsule. | Evid Based Complement Alternat Med. 2014;2014:592319. doi: 10.1155/2014/592319. Epub 2014 Jul 23. | Kidney | Clinic |
| 25152761 | Even, the pain intensity of the ureteral pelvis junction (UPJ) and the upper part of the ureter is lower than the area around the kidney during ESWL operation. | Evid Based Complement Alternat Med. 2014;2014:592319. doi: 10.1155/2014/592319. Epub 2014 Jul 23. | Kidney | Clinic |
| 24137250 | The following cases were excluded from this study: patients with immune, renal or central nervous system dysfunction, patients with congestive heart failure, exogenous hormone therapy (including steroids), prior experience of acupuncture, pregnancy, malnutrition, diabetes, malignancy, infection or inflammation. | Exp Ther Med. 2013 Sep;6(3):699-702. doi: 10.3892/etm.2013.1225. Epub 2013 Jul 16. | Immunity Kidney | Clinic |
| 28658163 | Inclusion criteria of the present study were as follows: American Society of Anesthesiologistsxe2x80x99 physical status classes I and II; no history of traumatic brain injury, neurological diseases, and alcohol abuse; no cognitive dysfunction; no severe vision or hearing impairment and no obvious abnormality of heart, lung, liver, and kidney function. | Medicine (Baltimore). 2017 Jun;96(26):e7375. doi: 10.1097/MD.0000000000007375. | Cognitive Function Kidney | Clinic |
| 31915045 | Exclusion criteria were recent use of TEAS or acupuncture, neural damage or infection along the meridian at which the acupoints lay, use of antiemetic in the previous week, regular use of opioids, hepatic dysfunction, confirmed renal impairment, diabetes mellitus, cognitive dysfunction and conversion to laparotomy during gynecologic laparoscopy. | Trials. 2020 Jan 8;21(1):43. doi: 10.1186/s13063-019-3892-4. | Cognitive Function Kidney | Clinic |
| 33488793 | The exclusion criteria were as follows: i) Body mass index >30 kg/m2; ii) severe cardiac or respiratory diseases, significant renal or hepatic impairment or immune disorders; iii) history of immunosuppressive therapy (chemotherapy or radiation) or previous acupuncture/TAES therapies; iv) history of chronic pain, steroid or opioid administration, or alcohol or illegal substance abuse; v) high levels of C-reactive protein or leukocytosis (>10,000/ml) prior to surgery; and vi) puncture site infection or systemic infection. | Exp Ther Med. 2021 Mar;21(3):184. doi: 10.3892/etm.2021.9615. Epub 2021 Jan 7. | Immunity Kidney | Clinic |
| 36749304 | Conventional analgesia medicine could increase the risk of nausea, vomiting and other digestive system side effects, abnormal liver/ renal functions, and inhibit bone formation and healing (Zhao & Davis,). | Brain Behav. 2023 Mar;13(3):e2913. doi: 10.1002/brb3.2913. Epub 2023 Feb 7. | Gastrointestinal Tract Side Effects Nausea and Vomiting Kidney | Clinic |
| 36749304 | The excluded criteria included (1) a history of neurological and psychiatric disorders, or head trauma with loss of consciousness; (2) serious renal, cardiovascular, respiratory or other organic diseases; (3) any contraindications to rsxe2x80x90fMRI scanning (such as defibrillator, cardiac pacemaker, metal stents or electronic implant, intraocular mental foreign body, claustrophobia, and hyperpyrexia); (4) unwillingness to sign the consent form; (5) having received acupuncture/EA in the past three months. | Brain Behav. 2023 Mar;13(3):e2913. doi: 10.1002/brb3.2913. Epub 2023 Feb 7. | Cardiovascular Kidney | Clinic |
| 36749304 | No skin ulcer, hematoma, infection, liver or kidney injury, or other adverse events was observed. | Brain Behav. 2023 Mar;13(3):e2913. doi: 10.1002/brb3.2913. Epub 2023 Feb 7. | Kidney | Clinic |
| 34622872 | The outcomes are changes of numerical rating scale, Karnofsky performance score, brief pain inventory, blood routine, liver and kidney function. | Medicine (Baltimore). 2021 Oct 8;100(40):e27461. doi: 10.1097/MD.0000000000027461. | Kidney | Clinic |
| 34622872 | with abnormal renal or liver function; | Medicine (Baltimore). 2021 Oct 8;100(40):e27461. doi: 10.1097/MD.0000000000027461. | Kidney | Clinic |
| 34622872 | The secondary outcomes are Karnofsky performance score, brief pain inventory, blood routine, liver and kidney function before and after the treatment. | Medicine (Baltimore). 2021 Oct 8;100(40):e27461. doi: 10.1097/MD.0000000000027461. | Kidney | Clinic |
| 24875645 | Qufeng Tongluo acupuncture prevents the progression of glomerulonephritis by decreasing renal sympathetic nerve activity. | J Ethnopharmacol. 2014 Aug 8;155(1):277-84. doi: 10.1016/j.jep.2014.05.019. Epub 2014 May 27. | Kidney | Mechanism |
| 24875645 | ETHNOPHARMACOLOGICAL RELEVANCE: Although the exact mechanism(s) underlying acupuncture remain unknown, acupuncture and acupuncture-like somatic nerve stimulation have been used to treat different kidney diseases and several complications related to them.The aim of this preliminary study was to assess the effectiveness of acupuncture on glomerulonephritis (GN) according to the theory of ""Wind-hided renal collaterals"" previously proposed. | J Ethnopharmacol. 2014 Aug 8;155(1):277-84. doi: 10.1016/j.jep.2014.05.019. Epub 2014 May 27. | Kidney | Mechanism |
| 24875645 | RESULTS: After immunization, our results showed that compared to the cBSA+MET and cBSA+IRB medication groups, ""Qufeng Tongluo"" significantly lowered parameters of renal function and improved podocyte injury in the 3rd, 6th and 8th weeks of treatment. | J Ethnopharmacol. 2014 Aug 8;155(1):277-84. doi: 10.1016/j.jep.2014.05.019. Epub 2014 May 27. | Immunity Kidney | Mechanism |
| 24875645 | CONCLUSIONS: Our study suggests that a potential mechanism by which acupuncture has an antihypertensive effect and can significantly halt deteriorating renal function due to cBSA GN might be mediated by inhibiting the Erk1/2 MAPK pathway to reduce renal sympathetic nerve activity (RSNA). | J Ethnopharmacol. 2014 Aug 8;155(1):277-84. doi: 10.1016/j.jep.2014.05.019. Epub 2014 May 27. | Kidney | Mechanism |
| 22964493 | The effect of electroacupuncture on insulin-like growth factor-I and oxidative stress in an animal model of renal failure-induced hypertension. | Kidney Blood Press Res. 2012;35(6):634-43. doi: 10.1159/000339640. Epub 2012 Sep 5. | Kidney | Mechanism |
| 22964493 | BACKGROUND/AIMS: The present study was performed to demonstrate the effect of electroacupuncture (EA) and acupuncture on renal failure (RF)-induced hypertension. | Kidney Blood Press Res. 2012;35(6):634-43. doi: 10.1159/000339640. Epub 2012 Sep 5. | Kidney | Mechanism |
| 22964493 | In blood analysis, the increment in RF-induced serum BUN and creatinine concentrations were decreased by EA (p < 0.05), and the decreases in RF-induced insulin-like growth factor-I (IGF-I) mRNA and protein levels were increased by EA in both the kidney and the serum (p < 0.05). | Kidney Blood Press Res. 2012;35(6):634-43. doi: 10.1159/000339640. Epub 2012 Sep 5. | Kidney | Mechanism |
| 12230028 | A total of 18 animals (two heifers and 16 cows) that had failed to conceive to 3-9 services were treated by aquapuncture, in which 10 ml and 5 ml of 50% glucose solution were injected at Baihui (Hundred Meetings, the depression in the center of the lumbosacral space) and Shenpeng (Kidney Shelf, the depression in the space between the lumbar vertebral transverse processes 5-6) acupoints, respectively with a 21G, 1.5-inch hypodermic needle. | Am J Chin Med. 2002;30(2-3):397-404. doi: 10.1142/S0192415X02000296. | Depression Kidney | Mechanism |
| 21721149 | Effects of acupuncture at Taixi acupoint (KI3) on kidney proteome. | Am J Chin Med. 2011;39(4):687-92. doi: 10.1142/S0192415X11009123. | Kidney | Mechanism |
| 21721149 | The kidneys were perfused with ice-cold saline and all kidney proteins were isolated. | Am J Chin Med. 2011;39(4):687-92. doi: 10.1142/S0192415X11009123. | Kidney | Mechanism |
| 21721149 | There were nine protein spots with three-fold up-regulation in the kidney after the acupuncture. | Am J Chin Med. 2011;39(4):687-92. doi: 10.1142/S0192415X11009123. | Kidney | Mechanism |
| 21721149 | The data indicated that acupuncture at the KI3 of the kidney meridian of the foot shaoyin was able to increase NAD-dependent isocitrate dehydrogenase and quinone reductase expression in the kidney, and supported the relationship between the kidney and KI3. | Am J Chin Med. 2011;39(4):687-92. doi: 10.1142/S0192415X11009123. | Kidney | Mechanism |
| 12269720 | Acupuncture stimulation inhibits somato-renal sympathetic A- and C-reflexes in anesthetized rats. | Acupunct Electrother Res. 2002;27(2):119-27. doi: 10.3727/036012902816026059. | Kidney | Mechanism |
| 12269720 | Stimulation of peripheral nerve afferent for example tibial nerve by a strong electrical stimulation (rectanfular wave with 20V amplitude; pulse duration of 0.5 ms, 0.3 pulses/sec) can evoke a discharge of the somato-sympathetic reflex which is recorded on the efferent of renal sympathetic nerve. | Acupunct Electrother Res. 2002;27(2):119-27. doi: 10.3727/036012902816026059. | Heart Rate Kidney | Mechanism |
| 12269720 | In the present study, an acupuncture needle (diameter 0.34 mm) was inserted into the hind limbs of the rat, dorsolaterally at the area of acupoint: huantiao (GB30), at a depth of 4-5 mm and was twisted right and left twice every second during recording the somato-renal sympathetic reflex. | Acupunct Electrother Res. 2002;27(2):119-27. doi: 10.3727/036012902816026059. | Kidney | Mechanism |
| 23384661 | The primary endpoints were levels of glucose, aspartate aminotransferase (AST), alanine aminotransferase (ALT) creatinine and histological changes of liver and kidney. | Acupunct Med. 2013 Jun;31(2):202-6. doi: 10.1136/acupmed-2012-010246. Epub 2013 Feb 5. | Kidney | Mechanism |
| 32989889 | For rear quarters affected by subclinical mastitis, the acupuncture points used were bladder (BL) 30, BL 30-1, BL 49, kidney (KI) 10, conception vessel (CV) 2 and CV 3. | Reprod Domest Anim. 2020 Dec;55(12):1747-1755. doi: 10.1111/rda.13835. Epub 2020 Oct 27. | Kidney | Mechanism |
| 35028961 | The protective effect of electroacupuncture on the renal cortex of SHRs: A metabonomic analysis. | Biomed Chromatogr. 2022 May;36(5):e5338. doi: 10.1002/bmc.5338. Epub 2022 Mar 21. | Kidney | Mechanism |
| 35028961 | How the protective effect of electroacupuncture on the renal cortex of the spontaneously hypertensive rat (SHR) is achieved has not yet been determined. | Biomed Chromatogr. 2022 May;36(5):e5338. doi: 10.1002/bmc.5338. Epub 2022 Mar 21. | Kidney | Mechanism |
| 35028961 | The purpose of this study was to understand the impact of electroacupuncture on the blood pressure of SHRs and the impact on metabolites in the renal cortex, looking for potential differential metabolites and then proceeding to the next step of exploratory research. | Biomed Chromatogr. 2022 May;36(5):e5338. doi: 10.1002/bmc.5338. Epub 2022 Mar 21. | Blood Pressure Kidney | Mechanism |
| 35028961 | Electroacupuncture on bilateral Taichong (LR3) and Zusanli (ST36) lasted for 3 weeks, and the renal cortex was collected for metabonomics research. | Biomed Chromatogr. 2022 May;36(5):e5338. doi: 10.1002/bmc.5338. Epub 2022 Mar 21. | Kidney | Mechanism |
| 35028961 | UHPLC-MS was used to analyze the changes in the metabolic spectrum of renal cortex tissue. | Biomed Chromatogr. 2022 May;36(5):e5338. doi: 10.1002/bmc.5338. Epub 2022 Mar 21. | Kidney | Mechanism |
| 35028961 | A total of 12 metabolites changed significantly in the comparison between each group and the model group.The possible mechanism is that the primary bile acid biosynthesis, bile secretion, tryptophan metabolism and other metabolic pathways affect the renal cortex. | Biomed Chromatogr. 2022 May;36(5):e5338. doi: 10.1002/bmc.5338. Epub 2022 Mar 21. | Kidney | Mechanism |
| 24928377 | The lung, liver, spleen, and kidney were examined for the concentration of Paclitaxel seperately. | Chin J Integr Med. 2014 Jun 13. doi: 10.1007/s11655-014-1819-1. | Kidney | Mechanism |
| 24928377 | RESULTS: Paclitaxel was widely distributed in various organs, particularly in the lung, liver, and kidney. | Chin J Integr Med. 2014 Jun 13. doi: 10.1007/s11655-014-1819-1. | Kidney | Mechanism |
| 24928377 | Acupuncture at Lingtai or Feishu acupoints resulted in an obvious decrease of Paclitaxel distribution in kidney and delayed Paclitaxel distribution in liver. | Chin J Integr Med. 2014 Jun 13. doi: 10.1007/s11655-014-1819-1. | Kidney | Mechanism |
| 17322780 | Vertebral column diseases are related to kidney energetic deficiency of either Yin or Yang. | J Vet Sci. 2007 Mar;8(1):95-8. doi: 10.4142/jvs.2007.8.1.95. | Kidney | Mechanism |
| 17322780 | Other conditions can also cause IDD, such as trauma and/or repetitive exercise, latent blood deficiency in the post estrus period, and a natural decline of Kidney energy that occurs in geriatric dogs. | J Vet Sci. 2007 Mar;8(1):95-8. doi: 10.4142/jvs.2007.8.1.95. | Kidney | Mechanism |
| 17322780 | 3) used in this case were as follows: LI (Large Intestine) 4, LI11, GV (Governing Vessel) 14, LI15, BL (Bladder) 23, KI (Kidney) 3 transfixed with BL60, GB (Gallbladder) 39 transfixed with SP (Spleen) 6 and local cervical points. | J Vet Sci. 2007 Mar;8(1):95-8. doi: 10.4142/jvs.2007.8.1.95. | Kidney | Mechanism |
| 17322780 | The acupuncture points BL23 and KI3 were chosen to enhance Kidney energy; BL60 was chosen as a distal point to alleviate the cervical problem by drawing out pathogenic Qi and placing healthful Qi into the bladder channel; GB 39 was used because it is an influential point for marrow and SP6 was used to disperse dampness and enhance Qi, Xue, Spleen and Kidney energies. | J Vet Sci. 2007 Mar;8(1):95-8. doi: 10.4142/jvs.2007.8.1.95. | Kidney | Mechanism |
| 17322780 | The first formula was chosen to expel wind and dampness, enhance kidney and liver energy, help Qi/Xue circulation and alleviate pain. | J Vet Sci. 2007 Mar;8(1):95-8. doi: 10.4142/jvs.2007.8.1.95. | Kidney Circulation | Mechanism |
| 22984478 | Chronic hypertension is a major causative factor of morbidity and mortality, as uncontrolled hypertension can contribute to myocardial infarction, stroke, congestive heart failure, and renal failure. | PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12. | Kidney | Mechanism |
| 25139460 | Our previous study showed that the induction of HO-1 by LPS can cause protection of lung, kidney, and liver during endotoxic shock in rats, and up-regulation of HO-1 may become a novel protective strategy for organ injury during endotoxic shock. | Med Sci Monit. 2014 Aug 16;20:1452-60. doi: 10.12659/MSM.890736. | Toxic Side Effects Kidney | Mechanism |
| 34564665 | Although these treatments are used alone or in combination, there are side effects such as gastrointestinal disorders, exacerbation of heart failure (NSAIDs), hypertension, restriction of use in diabetic patients (corticosteroids), digestive side effects, and renal and nervous system toxicity (Col). | Toxins (Basel). 2021 Sep 16;13(9):661. doi: 10.3390/toxins13090661. | Gastrointestinal Tract Toxic Side Effects Side Effects Kidney | Mechanism |
| 35704659 | SP6, the intersecting point of Gan (liver), spleen channels (Pi) and kidney (Shen), can regulate the functions of the Gan, Pi and Shen, restoring Qi and blood flow movements. | PLoS One. 2022 Jun 15;17(6):e0259609. doi: 10.1371/journal.pone.0259609. eCollection 2022. | Kidney Blood Flow | Mechanism |
| 25302705 | Hspa1b, encodes stress-inducible 70-kDa heat shock proteins (HSP70) that protect cells from insults such as ischemia and reperfusion-induced damages in the heart and kidney. | Molecules. 2014 Oct 9;19(10):16158-78. doi: 10.3390/molecules191016158. | Kidney | Mechanism |
| 25302705 | As immediate-early genes, they have been investigated by numerous studies and showed to be protective to ischemia-reperfusion injury in the heart, brain, kidney, and liver. | Molecules. 2014 Oct 9;19(10):16158-78. doi: 10.3390/molecules191016158. | Kidney | Mechanism |
| 36510338 | Anders thinks that macrophage pyroptosis in the kidney can lead to renal inflammation and fibrosis. | Mol Pain. 2023 Jan-Dec;19:17448069221147792. doi: 10.1177/17448069221147792. | Kidney | Mechanism |
| 26345700 | BL23 is also commonly used in clinical practice, particularly for renal and pulmonary conditions. | Acupunct Med. 2016 Apr;34(2):107-13. doi: 10.1136/acupmed-2014-010674. Epub 2015 Sep 7. | Kidney | Mechanism |
| 26792101 | However, since rapamycin influences both upstream and downstream ALP, and broadly affects cell growth and metabolism, rapamycin-based treatments show adverse effects including dyslipidemias, anti-proliferative toxicity and renal dysfunction, which has intrigued intense interest in developing new drugs independent of mTOR or finding new therapeutic targets. | Sci Rep. 2016 Jan 21;6:19714. doi: 10.1038/srep19714. | Toxic Side Effects Adverse Reactions Kidney | Mechanism |
| 29981376 | Acupuncture decreases levels of norepinephrine and epinephrine in the plasma and renal tissues of spontaneously hypertensive rats and levels of norepinephrine in the hypothalamus of alcoholic rats. | J Pain. 2018 Dec;19(12):1384.e1-1384.e14. doi: 10.1016/j.jpain.2018.05.013. Epub 2018 Jul 4. | Kidney | Mechanism |
| 36536227 | The dogs without improvement had similar severity of IVDD (G2,3 and 5) as well as comorbid disorders, such as hypothyroidism, liver dysfunction, kidney failure, spondylosis, medial patella luxation, torticollis, or dementia. | Vet Res Commun. 2023 Jun;47(2):879-884. doi: 10.1007/s11259-022-10051-4. Epub 2022 Dec 19. | Kidney | Mechanism |
| 30906419 | Hypertension is a substantial public health problem, affecting over 1 billion people worldwide, and results in cardiovascular diseases and chronic kidney disease. | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Cardiovascular Kidney | Mechanism |
| 30906419 | As a major independent risk factor for myocardial infarction, stroke, and end-stage renal disease, hypertension is a multifactor disorder that can be triggered by mechanisms in the central nervous systems (CNS). | Evid Based Complement Alternat Med. 2019 Feb 18;2019:9541079. doi: 10.1155/2019/9541079. eCollection 2019. | Kidney | Mechanism |
| 26623337 | In traditional Chinese medicine it is assumed that bone healing activity is related to the kidney, not only in bone mineral supply, but also has great effects on bone growth of young animals. | Open Vet J. 2014;4(1):44-50. Epub 2014 Apr 25. | Kidney | Mechanism |
| 26623337 | In this study we tried to promote and accelerate bone healing with the acupuncture induced stimulation of kidney related acupoints in dog. | Open Vet J. 2014;4(1):44-50. Epub 2014 Apr 25. | Kidney | Mechanism |
| 26623337 | Study of literature showed that the stimulation of acupuncture points and balance in the Yin and Yan energy in kidney meridians and maintaining this balance and the use of Qi energy on fracture site can activate Bone growth factors in the bleeding to establish the ossifying procedure (Hayashi et al., 2008). | Open Vet J. 2014;4(1):44-50. Epub 2014 Apr 25. | Bleeding Kidney | Mechanism |
| 26623337 | Exploration of Traditional Chinese Medicine (TCM) has shown that bone tissue is linked with kidney energy, which can stimulate bone healing (Feng et al., 2008; Nakajima et al., 2010). | Open Vet J. 2014;4(1):44-50. Epub 2014 Apr 25. | Kidney | Mechanism |
| 26623337 | CGRP and VIP neuropeptides could be produced after acupuncture stimulation and released to a target organ (Hayashi et al., 2008), because they stimulate and degrade the activity of acupoints; B23 and K13 cause activity of kidney canal (Maciocia, 1996). | Open Vet J. 2014;4(1):44-50. Epub 2014 Apr 25. | Kidney | Mechanism |
| 30136700 | Kidney deficiency and Du meridian occlusion as a consequence of qi stagnation and blood stasis are regarded as the major cause of senile dementia based on Chinese medicine theory. | Neural Regen Res. 2018 Oct;13(10):1833-1841. doi: 10.4103/1673-5374.238620. | Kidney | Mechanism |
| 30136700 | Thus, the acupoints Shenshu (BL23) and Baihui (GV20) have usually been chosen to nourish kidney-essence and modify the Governor vessel. | Neural Regen Res. 2018 Oct;13(10):1833-1841. doi: 10.4103/1673-5374.238620. | Kidney | Mechanism |
| 36636219 | TCM believes that the liver, spleen and kidney are closely related to qi, blood, and yin and yang of the whole body, so the Sanyinjiao (SP6) point, which is related to these three viscera, is the third selected acupoint. | Heliyon. 2022 Dec 22;8(12):e12574. doi: 10.1016/j.heliyon.2022.e12574. eCollection 2022 Dec. | Kidney | Mechanism |
| 19531626 | Previously, laser Doppler blood flow imaging technique has been used to observe blood perfusion of the abdominal organs, such as liver, spleen, kidney, urinary bladder, stomach, intestinal tract and mesentery. | Evid Based Complement Alternat Med. 2011;2011:969231. doi: 10.1093/ecam/nep050. Epub 2010 Oct 20. | Kidney Blood Flow | Mechanism |
| 29623942 | Regulating the Qi of Sanjiao modulates spleen and stomach functions, enriching Qi and blood, tonifying the kidney, promoting blood circulation for blood stasis removal, eliminating phlegm, improving dementia symptoms, and retarding brain aging. | Neural Regen Res. 2018 Mar;13(3):541-548. doi: 10.4103/1673-5374.228760. | Kidney Circulation | Mechanism |
| 29623942 | The main ingredients of HuangDiSan are Chinese Angelica and Rehmannia, with the effects of dredging Sanjiao, tonifying Qi and regulating blood, as well as strengthening the root and tonifying the kidney. | Neural Regen Res. 2018 Mar;13(3):541-548. doi: 10.4103/1673-5374.228760. | Kidney | Mechanism |
| 24527041 | Its name translates into English as three Yin intersections, reflective of it being a meeting point of the three Yin channels of the leg (spleen, liver, and kidney). | Evid Based Complement Alternat Med. 2014;2014:216503. doi: 10.1155/2014/216503. Epub 2014 Jan 9. | Kidney | Mechanism |
| 34405366 | Lately, ferroptosis has been the subject of attention as it is a type of programmed cell demise that is implicated in malignancy, ICH, reperfusion damage following ischaemia and renal dysfunction, amongst additional pathologies (Stockwell et al. ; Sarhan et al. ). | J Mol Neurosci. 2022 Jan;72(1):82-96. doi: 10.1007/s12031-021-01890-y. Epub 2021 Aug 17. | Kidney | Mechanism |
| 30127121 | Previous studies have demonstrated that inhibiting the Shh pathway promotes apoptosis of cancer cells (Subramani et al., 2017; Xu et al., 2017), and also promotes apoptosis in traumatogenic diseases such as ischemia/reperfusion injury of skeletal muscle (Zeng et al., 2017) and kidney (Meng et al., 2016). | Neural Regen Res. 2018 Sep;13(9):1602-1608. doi: 10.4103/1673-5374.237123. | Kidney | Mechanism |
| 20981331 | According to the TCM principles, Sanyinjiao (SP6) is considered as a classic acupoint for female disorders and can soften and harmonize the liver and benefit the kidney Qi. | Evid Based Complement Alternat Med. 2011;2011:606514. doi: 10.1155/2011/606514. Epub 2010 Sep 30. | Kidney | Mechanism |
| 35069759 | Sanyinjiao (SP6), located on the tibial aspect of the leg, posterior to the medial border of the tibia and 3 B-cun (proportional bone cun), above the prominence of the medial malleolus, is the intersection point of liver, spleen, and kidney channels, which is closely related to the uterus with the effects of moving Qi and regulating blood. | Evid Based Complement Alternat Med. 2022 Jan 13;2022:4571981. doi: 10.1155/2022/4571981. eCollection 2022. | Kidney | Mechanism |
| 31485183 | Dizziness occurs as a result of failure of the clear yang to increase because of the lack of blood and under-nourishment of the brain due to blood stasis, under-nourishment of the channels and collaterals, obstructed vessels, and failure of deficient kidney qi and yang to drive blood circulation. | Saudi J Biol Sci. 2019 Feb;26(2):390-394. doi: 10.1016/j.sjbs.2018.11.011. Epub 2018 Nov 20. | Kidney Circulation | Mechanism |
| 25767501 | BL23 is the back-shu-acupoint of the kidney, and DU 20 and DU14 belong to the Du meridian which is closely associated with the regulation of the brain's function, so we electroacupunctured at BL23, DU20, and DU14 to invigorate the kidney, replenish the essence and improve the brain's function. | Neural Regen Res. 2012 Jan 25;7(3):207-11. doi: 10.3969/j.issn.1673-5374.2012.03.009. | Kidney | Mechanism |
| 31312613 | Ten time points were designed for blood collection at 0.033, 0.083, 0.167, 0.333, 0.833, 1.333, 2.333, 4.333, 6.333, and 24.333 h. Tissue samples, including heart, liver, spleen, lung, kidney, tumor (TG and EATG group), and skin from acupuncture area or non-acupuncture area (NG and EANG group), were excised at 0.033, 0.833, 2.333, 4.333, 6.333, and 24.333 h and stored at â80°C until used. | Front Oncol. 2019 Jul 2;9:576. doi: 10.3389/fonc.2019.00576. eCollection 2019. | Kidney | Mechanism |
| 31312613 | What's more, there were no significant differences in paclitaxel pharmacokinetic parameters in lung, liver, spleen, kidney, and heart between TG group and EATG group (Supplementary Table S1; Supplementary Figure S4). | Front Oncol. 2019 Jul 2;9:576. doi: 10.3389/fonc.2019.00576. eCollection 2019. | Kidney | Mechanism |
| 30106051 | Sanjiao pneumatolysis links to the five internal organs (heart, liver, spleen, lung, and kidney), with only correct gasification function necessary to ensure humans are disease-free. | Neural Regen Res. 2018 Aug;13(8):1390-1395. doi: 10.4103/1673-5374.235292. | Kidney | Mechanism |
| 28507480 | Human embryonic kidney cells (HEK) 293T cells were purchased from the Cell Bank of Type Culture Collection of Chinese Academy of Sciences (CCCAS, Shanghai, China). | EXCLI J. 2017 Mar 23;16:363-374. doi: 10.17179/excli2017-123. eCollection 2017. | Kidney | Mechanism |
| 31322212 | Acupuncture attenuates renal interstitial fibrosis via the TGF-β/Smad pathway | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Acupuncture is one of the most useful tools in complimentary medicine, and has demonstrated potential value for treating chronic renal failure (CRF). | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | In the present study, the effects of acupuncture on renal interstitial fibrosis (RIF) were explored in a rabbit model of CRF. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Chronic kidney disease (CKD) has become one of the major diseases that threatens public health worldwide, and causes an enormous amount of suffering and economic expense. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Therefore, there is a critical and urgent need to reduce the frequency of kidney injury and protect the kidneys from all types of kidney disease. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Renal interstitial fibrosis (RIF) is a kidney disorder characterized by dilated kidney tubules and interstitial fibrosis. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Studies have indicated that the degree of RIF indicates the degree of kidney damage, which makes RIF an important factor when establishing a prognosis for patients with kidney diseases. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | The occurrence and development of RIF are influenced by numerous factors, including renal tubular epithelial cell apoptosis, inflammation, cytokines, oxidative stress, fibroblast proliferation and activation, the production of vasoactive substances, and an imbalance between extracellular matrix synthesis and degradation. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Renal fibrogenesis is related to multiple cellular events and molecular mediators. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Among the fibrogenic factors that regulate the renal fibrotic process, transforming growth factor β (TGF-β) has long been considered as a central mediator of the fibrotic response. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | In the present study a rabbit model of CRF was utilized to explore the renal protective effect of acupuncture and the underlying mechanism for that effect. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Chronic renal failure (CRF) model | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | After 21 days, their kidney function, blood pressure and urinary protein levels were measured. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Blood Pressure Kidney | Mechanism |
| 31322212 | Renal function analysis | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Comparison of renal function in the control and CRF model groups | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Our chronic renal failure (CRF) model was created by gavaging rabbits with adenine for 3 weeks. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Acupuncture attenuates kidney fibrogenesis and pathological changes in the CRF model rabbits | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | To explore how acupuncture affects RIF, H&E and Masson's trichrome staining were performed to evaluate morphological features of the renal tissues. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | TGF-β expression was detected by an IHC assay, and the results showed that TGF-β was rarely found in the control group, but was highly expressed in renal tissues (mainly in injured tubulointerstitium and renal tubular epithelial cells). | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Renal interstitial fibrosis (RIF) is the main pathological change that occurs in various types of chronic kidney disease (CKD) and inevitably progresses to end-stage renal disease (ESRD). | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | The extent of RIF is correlated with the progression of renal disease. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Therefore, it is important to alleviate any renal injury and its associated RIF. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | The essence of renal insufficiency is the associated decrease in the glomerular filtration rate (GFR). | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | SCr and BUN levels are good indicators of GFR, and are widely used to evaluate renal function. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Therefore, it was demonstrated that the renal function of rabbits in the model group had been damaged, and the CRF model had been successfully constructed. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Research has proven that stimulation of Zusanli (ST36) by electro-acupuncture (EA) can inhibit a reduction of endothelial nitric oxide synthase in the blood, reduce renal artery pressure, and protect kidney function. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Research has shown that periorbital acupuncture reduced the severity of a chemically induced renal injury in animals. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | For example, fatigue can be improved by massaging Yanglingchuan (GB34), Sanyinjiao (SP6) and Zusanli; sleep disturbances can be treated by Hand Shenmen (HT7) and Ear Shenmen (MATF1); acupuncture or acupressure on Hegu (LI4) can relieve pain and exert anti-inflammatory effects; acupuncture on Taixi (KI3) can relieve renal disease, cognitive disorders and impotence. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Insomnia Kidney | Mechanism |
| 31322212 | It is generally known that losartan potassium, an angiotensin II (Ang II) receptor antagonist, can disrupt the angiotensin system, and thereby reduce proteinuria and delay chronic renal dysfunction. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | During the development of RIF, EMT is defined as the process by which renal epithelial cells and fibroblasts become altered to form myofibroblasts. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | In addition, fibroblasts, one of the main intrinsic cells in the renal interstitium, are the main cells that secrete ECM during the development of RIF. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | The TGF-β/Smad pathway plays a critical role in renal fibrosis and also inflammation. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Researchers have suggested the TGF-β/Smad pathway as a potential therapeutic target for treating chronic kidney diseases. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | These findings suggest that acupuncture can effectively reduce the typical kidney features of CRF, and promote the recovery of renal function by inhibiting the TGF-β/Smad pathway. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Comparison of renal function in the control and CRF model groups. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | Acupuncture attenuates pathological characteristics and fibrogenesis in the kidney. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | The pathological characteristics of kidney tissues were examined by (A) H&E and (B) Masson trichrome staining assays. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 31322212 | TGF-β, transforming growth factor β; IL-8, interleukin 8; TNF-α, tumor necrosis factor-α; IL-1β, interleukin-1β; CRF, chronic renal failure. | Mol Med Rep. 2019 Sep;20(3):2267-2275. doi: 10.3892/mmr.2019.10470. Epub 2019 Jul 4. | Kidney | Mechanism |
| 24665334 | Acupoint SP6 pertains to spleen meridian of foot greater yin and is a crossing point of three yin meridians of foot (such as spleen meridian, liver meridian, and kidney meridian). | Evid Based Complement Alternat Med. 2014;2014:595963. doi: 10.1155/2014/595963. Epub 2014 Feb 10. | Kidney | Mechanism |
| 24665334 | So, SP6 has the function of regulating meridian qi of the liver, spleen, and kidney, tonifying spleen earth, promoting transportation and transformation, dredging qi stagnation, regulating blood and the uterus, and removing wind dampness from the meridian and collaterals. | Evid Based Complement Alternat Med. 2014;2014:595963. doi: 10.1155/2014/595963. Epub 2014 Feb 10. | Kidney | Mechanism |
| 26998388 | Tissue from a kidney in the intravenous single-dose toxicity study of WSGP in SD rats. | J Pharmacopuncture. 2015 Dec;18(4):38-44. doi: 10.3831/KPI.2015.18.036. | Toxic Side Effects Kidney | Mechanism |
| 32967614 | Feishu (BL13), Pishu (BL20), and Shenshu (BL23) are back-shu points of the lung, spleen, and kidney that can regulate the function of these organs, and achieve the purpose of strengthening the spleen and benefiting the lung, enriching the kidney and strengthening Yang-qi. | J Physiol Sci. 2020 Sep 23;70(1):45. doi: 10.1186/s12576-020-00769-8. | Kidney | Mechanism |
| 31045558 | Tranquilize Mind and Regulate Kidney (TMRK) electroacupuncture method was performed in each rat in the SPS+EA and SPS&S+EA groups, the treatment lasted for 20 minutes per day, simultaneously for 3 consecutive weeks. | Technol Health Care. 2019;27(S1):425-443. doi: 10.3233/THC-199038. | Kidney | Mechanism |
| 31045558 | Essence in the kidney is the material basis for the formation, development and function of the brain and for maintaining the mental activity and behavior of the entire human body. | Technol Health Care. 2019;27(S1):425-443. doi: 10.3233/THC-199038. | Kidney | Mechanism |
| 31045558 | In summary, in response to the decline of fear memory, we should start from tonifying the kidney and waking up the brain. | Technol Health Care. 2019;27(S1):425-443. doi: 10.3233/THC-199038. | Kidney | Mechanism |
| 31045558 | In the clinical research on PTSD, we have confirmed that electroacupuncturing Baihui, Shenting to refresh the mind and nerves, Shenshu to regulate the kidney, significantly promoted the decline of fear memory . | Technol Health Care. 2019;27(S1):425-443. doi: 10.3233/THC-199038. | Kidney | Mechanism |
| 34646336 | Obesity has been identified as a cause of esophageal cancer, colon cancer, uterine cancer, kidney cancer, and postmenopausal breast cancer. | Comput Math Methods Med. 2021 Oct 4;2021:6730274. doi: 10.1155/2021/6730274. eCollection 2021. | Kidney | Mechanism |
| 22553490 | Acupuncture also nourishes the Kidney Yin at Sanyinjiao and improves production of Qi and blood at Zusanli, which are regarded as necessaries for fertility. | Spermatogenesis. 2012 Jan 1;2(1):53-62. doi: 10.4161/spmg.19282. | Kidney | Mechanism |
| 25206919 | The combined use of Shenshu and Baihui could replenish the kidney essence and marrow, and promote resuscitation. | Neural Regen Res. 2014 May 1;9(9):968-72. doi: 10.4103/1673-5374.133148. | Kidney | Mechanism |
| 37635258 | The small animal in vivo optical imager (PerkinElmer, Shanghai, China) was used to image the heart, liver, spleen, lung, and kidney of a mouse after DiR and DiR-Acu-exo injection 2Â h, 4Â h at each time point. | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Kidney | Mechanism |
| 37635258 | Five organs: Brain, Liver, Gastrointestinal tract, Lung, Kidney. | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Gastrointestinal Tract Kidney | Mechanism |
| 29849693 | Diabetic nephropathy is a common and serious complication of diabetes and a major cause of end-stage renal disease. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | Transmission electron microscopy was used to observe morphological changes, and protein expression levels of nephrin, CD2AP, podocalyxin, and desmin were quantified in renal tissue. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | Simultaneously, ACU promoted the renal expression of nephrin, CD2AP, and podocalyxin and decreased the expression of desmin. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | Diabetic nephropathy (DN) is one of the most common and serious complications of diabetes and is a major cause of end-stage renal disease (ESRD). | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | Yet, this regimen provides incomplete protection against renal failure, such that the prevalence of DN remains high. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | Acupuncture and acupuncture-like somatic nerve stimulation have also been successfully used to treat different kidney diseases and related complications such as gouty renal damage and renal disease progression. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | Renal cortex tissues were fixed in a fixation fluid for transmission electron microscopy and the remaining kidney tissue was stored at â80°C until western blotting analysis. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | Renal Histology | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | After sacrifice and abdominal cavity blood sampling, the bilateral kidneys were excised and the renal cortex was fixed in 3% glutaraldehyde, postfixed in 1% osmium tetroxide, imbued with uranyl acetate, and embedded in epoxy resin (Epon). | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | Total protein in renal cortex tissues was extracted and protein concentrations were measured using a BCA kit. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | Effects of Tiaolipiwei Acupuncture on Renal Tissue Morphology | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | Given the role of podocyte lesions in DN-associated albuminuria, we examined renal morphology in treated and untreated rats using transmission electron microscopy. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | Ultrastructural observation of renal cortical tissue from control group rats revealed normal GBMs without foot process fusion (Figure 3(a), A, D, and G). | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | Effects of Tiaolipiwei Acupuncture on Renal Nephrin, CD2AP, Desmin, and Podocalyxin Expression | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | We next examined the renal expression of podocyte proteins involved in slit diaphragm regulation. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | After at least 4 weeks of daily treatment, acupuncture reduced albuminuria, improved indicators of renal function, and regulated blood lipids in DN model rats. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | Podocytes are the last barrier between the renal artery and the primary urine and are the first major site of damage in DN. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | Additionally, several studies have shown that the accumulation of cholesterol in podocytes can contribute to podocyte damage and accelerate the progression of kidney disease. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | This process leads to the deficiency of the kidney because it cannot be nourished, and this further aggravates the proteinuria. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | Markers of kidney function and blood lipids in each group. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | (a) Ultrastructural features of the renal cortex observed under transmission electron microscopy in all groups. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 29849693 | Protein expression in the renal cortex in all groups. | Evid Based Complement Alternat Med. 2018 Apr 23;2018:1913691. doi: 10.1155/2018/1913691. eCollection 2018. | Kidney | Mechanism |
| 19696195 | We extracted total RNA from various tissues (brain, skeletal muscle, heart, lung, spleen, liver and kidney) obtained from non-EA-treated mice by using the TRIzol reagent (Invitrogen, Carlsbad, CA, USA) method. | Evid Based Complement Alternat Med. 2011;2011:249280. doi: 10.1093/ecam/nep121. Epub 2011 Feb 17. | Kidney | Mechanism |
| 19696195 | All tissues, brain, skeletal muscle, spleen, heart, lung, kidney and liver, expressed the Aig1l gene as determined by semiquantitative RT-PCR: the highest expression was found in the brain (data not shown). | Evid Based Complement Alternat Med. 2011;2011:249280. doi: 10.1093/ecam/nep121. Epub 2011 Feb 17. | Kidney | Mechanism |
| 19696195 | The following tissues expressed the Aig1l gene in (a) and (b): brain, B; muscle, M; heart, H; lung, Lu; spleen, S; liver, L and kidney, K. NC indicates negative control. | Evid Based Complement Alternat Med. 2011;2011:249280. doi: 10.1093/ecam/nep121. Epub 2011 Feb 17. | Kidney | Mechanism |
| 28386185 | In recent years, with further researches on Ciri rats, and rapid development of modern pharmacology in traditional Chinese medicine, the study variety has been extended to include expectorant Xingshen, (breathing and resuscitation), Yiqi Bushen (replenishing qi and tonifying the kidney), Huazhuo Jiedu (resolving turbidity and toxin). | Saudi J Biol Sci. 2017 Mar;24(3):595-602. doi: 10.1016/j.sjbs.2017.01.031. Epub 2017 Jan 23. | Kidney | Mechanism |
| 28761425 | The location of the disease is in the brain, and strongly associated with the heart, liver, spleen and kidney. | Neural Regen Res. 2017 Jun;12(6):925-930. doi: 10.4103/1673-5374.208574. | Kidney | Mechanism |
| 25887143 | Taking the neuron discharge as the index, the observation was performed at 33 acupoints of the different regions with acupuncture, namely Ganshu (BL18), Shenshu (BL23), Chengshan (BL57), and Dashu (BL11) of the Bladder Channel; Jingmen (GB25), Yanglingquan (GB34), Riyue (GB24) and Fengchi (GB20) of the Gallbladder Channel; Tianshu (ST25), Zusanli (ST36), Wuyi (ST15) and Futu (ST32) of the Stomach Channel; Zhubin (KI9), Shangqu (KI17) and Futonggu (KI20) of the Kidney Channel; Taichong (LR3), Zhangmen (LR13) and Qimen (LR14) of the Liver Channel; Sanyinjiao (SP6), Fuai (SP16) and Daheng (SP15) of the Spleen Channel; Hegu (LI4) of the Large Intestine Channel, Waiguan (TE5) of the Triple Energizers Channel, Yanglao (SI6) of the Small Intestine Channel, Taiyuan (LU9) of the Lung Channel, Neiguan (PC6) of the Pericardium Channel, Shenmen (HT7) of the Heart Channel, Shuigou (DU26), Dazhui (DU14) and Mingmen (DU4) of Du Channel, Shanzhong (RN17) and Zhongwan (RN14) of Ren Channel and Auricular Concha Region (ACR). | BMC Complement Altern Med. 2015 Mar 27;15:87. doi: 10.1186/s12906-015-0625-4. | Kidney | Mechanism |
| 25120577 | It governs human life activities through qi from brain combine qi from kidney together then to trigger other organs' qi. | Evid Based Complement Alternat Med. 2014;2014:962343. doi: 10.1155/2014/962343. Epub 2014 Jul 10. | Kidney | Mechanism |
| 26392912 | It is used to reinforce the vital function of the kidney and to strengthen the bones and muscles for the treatment of intolerance to cold, loss of strength, impotence, spontaneous seminal emission and other symptoms due to a deficiency of a vital function in chronic diseases. | J Pharmacopuncture. 2015 Sep;18(3):42-8. doi: 10.3831/KPI.2015.18.023. | Kidney | Mechanism |
| 36116306 | The Sanyinjiao point has the effect of supporting Yin and spleen, ventilation stagnation, reducing humidity and wind, regulating blood, improving the liver and kidney. | Int J Surg Case Rep. 2022 Oct;99:107600. doi: 10.1016/j.ijscr.2022.107600. Epub 2022 Sep 7. | Kidney | Mechanism |