- The advantages of acupuncture anesthesia in clinical practice
In clinical practice, acupuncture anesthesia presents a multitude of advantages, pivotal among these being Body System Protection. This technique supports the body's natural defenses, reducing the physiological stress often associated with surgical procedures. By modulating the body's response to pain, acupuncture anesthesia allows for a lower Dosage of Medication, significantly reducing the potential for drug-related side effects. Furthermore, this approach plays a crucial role in Emotion Regulation, helping patients maintain a calm and stable emotional state, which is essential for a positive surgical outcome. The impact of acupuncture on the nervous system not only aids in Pain Relief but also promotes Enhanced Recovery After Surgery. Patients tend to experience faster recuperation times, attributed to the holistic nature of this method. Additionally, acupuncture anesthesia is associated with a Lower Incidence of Side Effects compared to conventional anesthetics. Its ability to modulate and balance the body's responses makes it an invaluable tool in the realm of modern medicine, offering a safer, more patient-centered approach to pain management and recovery.
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Body System Protection
- Brain Protection
- Acupuncture anesthesia plays a vital role in brain surgeries, ensuring precise and safe anesthesia, reducing the risk of neurological complications, and supporting optimal cognitive function.
- Lung Protection
- Acupuncture anesthesia reduces post-operative lung complications, aiding in rapid lung function recovery, particularly beneficial for lung surgeries.
- Neuroprotection
- Acupuncture anesthesia is crucial for safeguarding the nervous system, reducing nerve injuries, and preventing the progression of neurological disorders.
- Kidney
- Acupuncture anesthesia alleviates stress on the kidneys, reducing the risk of kidney injury, particularly valuable in kidney surgeries.
- Gastrointestinal Tract
- Acupuncture anesthesia supports gastrointestinal health, reducing the risk of post-operative digestive issues, and ensuring a smoother recovery.
- Cardiovascular
- Acupuncture anesthesia eases the cardiovascular system's burden, reducing the risk of cardiovascular complications, especially in cardiac surgeries.
- Myocardium
- Acupuncture anesthesia aids in protecting the myocardium, minimizing adverse effects on heart muscle, ensuring cardiac health.
- Cognitive Function
- Through emotional stability and neuroprotection, acupuncture anesthesia helps preserve cognitive function, reducing the risk of post-operative cognitive impairment.
- Motor Function
- Acupuncture anesthesia improves motor function, aiding in post-operative mobility, and enhancing overall quality of life.
- Language Function
- Acupuncture anesthesia supports language function rehabilitation, assisting patients in regaining their communication skills.
- Learning and Memory Ability
- Acupuncture anesthesia, by reducing post-operative pain and emotional instability, enhances learning and memory ability, promoting a speedy recovery.
Acupuncture anesthesia for Body System Protection-Motor Function
| PMID | Evidence | Source | Keyword | Type |
|---|---|---|---|---|
| 16856031 | One trial showed no significant improvement of motor function between the real acupuncture group and the sham acupuncture group (OR 9.00, 95% CI 0.40 to 203.30), but the confidence interval was wide and included clinically significant effects in both directions. | Cochrane Database Syst Rev. 2006 Jul 19;(3):CD004131. doi: 10.1002/14651858.CD004131.pub2. | Motor Function | Review |
| 20451467 | Western descriptions of the clinical efficacy of acupuncture on pain, inflammation, motor dysfunction, mood disorders, and seizures are based on the stimulation of several classes of sensory afferent fibers and the consequent activation of physiological processes similar to those resulting from physical exercise or deep massage. | Auton Neurosci. 2010 Oct 28;157(1-2):9-17. doi: 10.1016/j.autneu.2010.03.020. Epub 2010 May 7. | Mood Motor Function | Review |
| 20494626 | Acupuncture has been used for analgesia, for treating visceral function disorders and for improving motor functions. | Auton Neurosci. 2010 Oct 28;157(1-2):2-8. doi: 10.1016/j.autneu.2010.03.004. Epub 2010 May 23. | Motor Function | Review |
| 20494626 | Secondly, we discuss what types of afferent nerve fiber are activated by electrical acupuncture, and what types are involved in its effects on somato-motor functions and on visceral functions. | Auton Neurosci. 2010 Oct 28;157(1-2):2-8. doi: 10.1016/j.autneu.2010.03.004. Epub 2010 May 23. | Motor Function | Review |
| 21701996 | Western descriptions of the clinical efficacy of acupuncture on pain, inflammation, motor dysfunction, mood disorders, and seizures are based on the stimulation of several classes of sensory afferent fibers and the consequent activation of physiological processes similar to those resulting from physical exercise or deep massage. | Arch Ital Biol. 2011 Jun;149(2):247-55. doi: 10.4449/aib.v149i2.1365. | Mood Motor Function | Review |
| 23546633 | OBJECTIVE: To evaluate the effectiveness of scalp acupuncture (SA), a modern acupuncture technique specialized to neurological disorders, in managing motor function and symptoms for Parkinson's disease (PD) patients. | Chin J Integr Med. 2013 Apr;19(4):297-306. doi: 10.1007/s11655-013-1431-9. Epub 2013 Apr 2. | Motor Function | Review |
| 26079978 | Pooled analyses showed that acupuncture may have a beneficial effect on neurological recovery (RRs: 1.28, 95% confidence interval [CI]: 1.12-1.50), motor function (WMD: 6.86, 95% CI: 0.41-13.31), and functional recovery (SMD: 0.88, 95% CI: 0.56-1.21) and all statistical approaches concurred. | J Neurotrauma. 2015 Dec 15;32(24):1943-57. doi: 10.1089/neu.2014.3866. Epub 2015 Aug 28. | Motor Function | Review |
| 29071970 | The results of Meta-analysis showed that the clinical effect was improved with acupuncture at meridian sinew as compared with normal acupuncture technique[1 in circletotal effective rate:OR=3.86, 95% CI (2.67,5.57), Z=7.20, P<0.00001; 2 in circlemodified Ashworth spasm scale:OR=4.54, 95% CI (2.91,7.10), Z=6.64, P<0.00001; 3 in circleevaluation of limb motor function with Fugl-Meyer score:MD=4.18, 95% CI (-0.59,8.94), Z=1.72, P=0.09>0.05. | Zhen Ci Yan Jiu. 2017 Apr 25;42(2):178-82. | Motor Function | Review |
| 29180347 | Accordingly, acupuncture combined with Madopar appeared to have a positive effect on activities of daily life and the general condition of patients with PD, but was not better than Madopar alone for the treatment of mental activity, behaviour, mood and motor disability. | Acupunct Med. 2017 Dec;35(6):404-412. doi: 10.1136/acupmed-2016-011342. Epub 2017 Nov 27. | Mood Motor Function | Review |
| 29631145 | Warm-needle moxibustion was found to be superior to electroacupuncture or acupuncture in reducing spasm and in promoting motor function and daily living activities. | Int J Nurs Stud. 2018 Jun;82:129-138. doi: 10.1016/j.ijnurstu.2018.03.013. Epub 2018 Mar 22. | Motor Function | Review |
| 29631145 | Pooled results for spasm effect and motor function were significant when warm-needle moxibustion was compared with electroacupuncture or acupuncture. | Int J Nurs Stud. 2018 Jun;82:129-138. doi: 10.1016/j.ijnurstu.2018.03.013. Epub 2018 Mar 22. | Motor Function | Review |
| 30408516 | Some researches suggest that acupuncture has therapeutic potential to help improve limb movement function and decrease the severity of spasticity. | Ann Phys Rehabil Med. 2019 Jul;62(4):297-301. doi: 10.1016/j.rehab.2018.09.010. Epub 2018 Nov 5. | Motor Function | Review |
| 30408516 | Moderate-quality evidence suggests that electroacupuncture combined with conventional routine care (pharmacological/rehabilitation) could reduce spasticity and improve motor function and activities in daily living after stroke. | Ann Phys Rehabil Med. 2019 Jul;62(4):297-301. doi: 10.1016/j.rehab.2018.09.010. Epub 2018 Nov 5. | Motor Function | Review |
| 30535303 | Acupuncture has demonstrated beneficial roles in the regulation of gut dysbiosis, intestinal barrier function, visceral hypersensitivity, gut motor dysfunction, depression/anxiety, and pain, all of which are factors that can significantly impact quality of life in patients with inflammatory bowel disease. | Inflamm Bowel Dis. 2019 Jun 18;25(7):1129-1139. doi: 10.1093/ibd/izy371. | Anxiety Depression Motor Function | Review |
| 32186072 | Meta-analysis revealed significant differences in the total efficacy rates of the SA group and the body acupuncture (BA) group vs the medication group (P < 0.002, P < 0.000 001, respectively), the SA plus BA group vs the BA group (P < 0.001); in the motor function of the SA plus BA group vs the BA group (P = 0.077); and in the nerve function of the SA group vs the SA plus BA group (P < 0.0001). | J Tradit Chin Med. 2018 Aug;38(4):465-479. | Motor Function | Review |
| 35580471 | These results indicated that acupuncture improved cognitive function, activities of daily living (ADLs), and motor function and relieved the degree of USN in patients with USN after stroke. | Geriatr Nurs. 2022 Jul-Aug;46:13-20. doi: 10.1016/j.gerinurse.2022.04.022. Epub 2022 May 14. | Cognitive Function Motor Function | Review |
| 35580471 | CONCLUSION: Acupuncture could promote the rehabilitation of cognitive function, ADLs, and motor function and relieve the symptoms of USN in patients with USN after stroke. | Geriatr Nurs. 2022 Jul-Aug;46:13-20. doi: 10.1016/j.gerinurse.2022.04.022. Epub 2022 May 14. | Cognitive Function Motor Function | Review |
| 35723122 | The benefits or risks associated with each intervention for spatial neglect including visual treatment, prism adaptation training, body awareness, mental function, movement treatment, non-invasive brain stimulation, electrical stimulation, and acupuncture remain unclear. | NeuroRehabilitation. 2022;51(2):347-350. doi: 10.3233/NRE-228022. | Motor Function | Review |
| 36153461 | Progress of researches on involvement of corticospinal tract in the effect of acupuncture on improvement of post-stroke motor dysfunction. | Zhen Ci Yan Jiu. 2022 Sep 25;47(9):843-6. doi: 10.13702/j.1000-0607.20210670. | Motor Function | Review |
| 36153461 | In the present paper, we reviewed the current development of researches on acupuncture treatment of poststroke motor dysfunction and its biological mechanisms from 1) delaying patients' development of neuronal degeneration and white matter fibrosis (Wallerian degeneration), 2) improving patients' upper limb motor function and daily life ability by promoting the repair of white matter tracts and CST on the affected side, 3) promoting the compensation of CST on the healthy side, 4) reconstructing the motor conduction pathway to strengthen the bilateral brain connection in ex-perimental animals, and 5) strengthening the sprouting of the contralateral CST to dominate the affected side again across the midline. | Zhen Ci Yan Jiu. 2022 Sep 25;47(9):843-6. doi: 10.13702/j.1000-0607.20210670. | Motor Function | Review |
| 36862302 | This review examines the current literature on integrative health modalities (anti-inflammatory diets, functional movement, acupuncture, meditation, and transcutaneous therapy) for treating patients with neuropathic pain. | Curr Pain Headache Rep. 2023 Apr;27(4):49-55. doi: 10.1007/s11916-023-01102-9. Epub 2023 Mar 2. | Neuropathic Pain Motor Function | Review |
| 36862302 | RECENT FINDINGS: The use of an anti-inflammatory diet, functional movement, acupuncture, meditation, and transcutaneous therapy in treating neuropathic pain has been investigated in prior literature with positive outcomes. | Curr Pain Headache Rep. 2023 Apr;27(4):49-55. doi: 10.1007/s11916-023-01102-9. Epub 2023 Mar 2. | Neuropathic Pain Motor Function | Review |
| 37070664 | CONCLUSIONS: Exercise appears to be a better form of physiotherapy than NiBS and acupuncture for improving motor function. | Biol Res Nurs. 2023 Oct;25(4):586-605. doi: 10.1177/10998004231171587. Epub 2023 Apr 18. | Motor Function | Review |
| 37248920 | CONCLUSION: Acupuncture treatment of beside bilateral spine acupoints plus lower limb acupoints therapy might facilitate early lower limb motor function recovery in children with BBPT-SCIWORA. | NeuroRehabilitation. 2023;53(1):161-166. doi: 10.3233/NRE-230006. | Motor Function | Review |
| 38039029 | CONCLUSIONS: Acupuncture as an adjunct to the management of post-stroke limb movement disorders contributes significantly to enhancing the motor function and quality of life of patients. | Eur Rev Med Pharmacol Sci. 2023 Nov;27(22):10985-10993. doi: 10.26355/eurrev_202311_34467. | Motor Function | Review |
| 38039029 | Therefore, high-quality randomized controlled trials are required to validate the benefits of acupuncture on the motor function of patients with post-stroke limb movement disorders. | Eur Rev Med Pharmacol Sci. 2023 Nov;27(22):10985-10993. doi: 10.26355/eurrev_202311_34467. | Motor Function | Review |
| 38084738 | This systematic review and meta-analysis were thus performed to comprehensively investigate the effects of acupuncture on the daily living abilities, upper and lower limb motor function, and related functional indices of post-stroke patients with spastic paralysis. | Int J Neurosci. 2023 Dec 12:1-8. doi: 10.1080/00207454.2023.2292955. | Motor Function | Review |
| 38084738 | CONCLUSION: Acupuncture therapy provides more pronounced improvement in the daily life ability and limb motor function of post-stroke patients with spastic paralysis than conventional treatment regimens. | Int J Neurosci. 2023 Dec 12:1-8. doi: 10.1080/00207454.2023.2292955. | Motor Function | Review |
| 38143390 | Acupuncture combined with repeated transcranial magnetic stimulation for upper limb motor function after stroke: A systematic review and meta-analysis. | NeuroRehabilitation. 2023;53(4):423-438. doi: 10.3233/NRE-230144. | Motor Function | Review |
| 38143390 | OBJECTIVE: Through a systematic review and meta-analysis of randomized controlled trials, this study aimed to assess the effectiveness of acupuncture combined with repetitive transcranial magnetic stimulation on upper extremity motor function in post-stroke patients. | NeuroRehabilitation. 2023;53(4):423-438. doi: 10.3233/NRE-230144. | Motor Function | Review |
| 38143390 | CONCLUSION: According to the results of the meta-analysis, we can conclude that acupuncture combined with repeated transcranial magnetic stimulation can significantly improve the upper limb motor function and daily living ability of stroke patients. | NeuroRehabilitation. 2023;53(4):423-438. doi: 10.3233/NRE-230144. | Motor Function | Review |
| 16824230 | Five studies proposed that acupuncture can have specific functional effects in the brain and used fMRI to correlate acupuncture points to specific areas of the brain with specific sensory or motor functions. | BMC Complement Altern Med. 2006 Jul 7;6:25. doi: 10.1186/1472-6882-6-25. | Motor Function | Review |
| 24407111 | After acupuncture therapy, patients showed improved recovery of motor function, reduced spasticity, relief of post-stroke depression, urinary incontinence or even reduction of infarction sizes. | Prog Neurobiol. 2014 Apr;115:246-69. doi: 10.1016/j.pneurobio.2013.12.007. Epub 2014 Jan 7. | Depression Urinary Incontinence Motor Function | Review |
| 24407111 | Some clinical studies combined acupuncture and Chinese herbal medicine for the treatment of post-stroke motor dysfunction. | Prog Neurobiol. 2014 Apr;115:246-69. doi: 10.1016/j.pneurobio.2013.12.007. Epub 2014 Jan 7. | Motor Function | Review |
| 25097658 | Furthermore, acupuncture-induced dopaminergic neuron protection and motor function improvement were significantly blocked by administration of LY294002, a specific inhibitor of PI3K/Akt signaling pathway. | Evid Based Complement Alternat Med. 2014;2014:483294. doi: 10.1155/2014/483294. Epub 2014 Jul 7. | Neuroprotection Motor Function | Review |
| 27705610 | In the rehabilitation phase after TBI, acupuncture improved overall functional outcome on the Barthel Index, Modified Barthel Index, motor function on the Fugl-Meyer Assessment, and muscle strength grading. | Nutr Neurosci. 2018 Feb;21(2):79-91. doi: 10.1080/1028415X.2016.1236174. Epub 2016 Oct 5. | Motor Function | Review |
| 28664077 | Acupuncture also facilitated motor function improvement against MPTP significantly, suggesting modulation of the phosphatidylinositol 3-kinase/Akt signaling pathway in a PD mouse model. | Integr Med Res. 2014 Jun;3(2):41-48. doi: 10.1016/j.imr.2014.03.003. Epub 2014 Apr 1. | Motor Function | Review |
| 28664077 | These results suggest that increased DA release after acupuncture treatment at GB34 may lead to enhanced DA availability in the synaptic cleft, which, in turn, may play an essential role in motor function improvement against MPTP. | Integr Med Res. 2014 Jun;3(2):41-48. doi: 10.1016/j.imr.2014.03.003. Epub 2014 Apr 1. | Motor Function | Review |
| 30538761 | We electronically searched the PubMed, Cochrane, and CNKI (China National Knowledge Infrastructure) databases using the following search terms: (weakness OR motor function disorder) (myasthenia gravis OR Guillain-Barre syndrome OR amyotrophic lateral sclerosis OR paralysis OR polymyositis OR muscular dystrophy) AND (herbal medicine OR acupuncture OR bee-venom OR pharmacoacupuncture OR electro-acupuncture OR moxibustion). | Evid Based Complement Alternat Med. 2018 Nov 13;2018:5601846. doi: 10.1155/2018/5601846. eCollection 2018. | Motor Function | Review |
| 30538761 | Key search terms were (myasthenia gravis OR Guillain-Barre syndrome OR amyotrophic lateral sclerosis OR paralysis OR polymyositis OR muscular dystrophy) AND (weakness OR motor function disorder) AND (herbal medicine OR acupuncture OR bee-venom OR pharmacoacupuncture OR electro-acupuncture OR moxibustion). | Evid Based Complement Alternat Med. 2018 Nov 13;2018:5601846. doi: 10.1155/2018/5601846. eCollection 2018. | Motor Function | Review |
| 30538761 | An animal study investigating the effect of bee venom pharmacoacupuncture on the central nervous system and muscle in an animal model of ALS showed that bee venom treatment at the Zusanli acupoint significantly enhanced motor function and decreased motor neuron death in the spinal cord compared to the control group. | Evid Based Complement Alternat Med. 2018 Nov 13;2018:5601846. doi: 10.1155/2018/5601846. eCollection 2018. | Motor Function | Review |
| 30681588 | Clinical studies have also shown that acupuncture improves motor function, alleviates adductor muscle tension, and promotes the development of intelligence in children with CP; therefore, it seems to be promising for the treatment of CP. | Medicine (Baltimore). 2019 Jan;98(4):e14187. doi: 10.1097/MD.0000000000014187. | Motor Function | Review |
| 31105643 | The overall meta-analysis showed that acupuncture combined with rehabilitation significantly improved motor function (upper-limb Fugl-Meyer Assessment (FMA): 34 studies, mean difference (MD) 8.01, 95% confidence interval (CI) [6.69,9.33]), and reduced pain (visual analog scale (VAS): 25 studies, MD â1.59, 95%CI [â1.86,â1.32]). | Front Neurol. 2019 Apr 26;10:433. doi: 10.3389/fneur.2019.00433. eCollection 2019. | Motor Function | Review |
| 31105643 | Conclusions: Acupuncture therapy seems effective for motor function, pain relief and activities of daily living in stroke patients with mild SHS, when it is used in combination with rehabilitation. | Front Neurol. 2019 Apr 26;10:433. doi: 10.3389/fneur.2019.00433. eCollection 2019. | Pain Relief Motor Function | Review |
| 31105643 | Three reviews published before 2010 showed acupuncture did not improve motor function or dependency outcomes after rehabilitation. | Front Neurol. 2019 Apr 26;10:433. doi: 10.3389/fneur.2019.00433. eCollection 2019. | Motor Function | Review |
| 31105643 | However, two more recently published reviews suggested acupuncture might aid rehabilitation in several areas, including motor function recovery and pain relief. | Front Neurol. 2019 Apr 26;10:433. doi: 10.3389/fneur.2019.00433. eCollection 2019. | Pain Relief Motor Function | Review |
| 31105643 | Thirty-four studies used FMA to evaluate acupuncture's effects on upper limb motor function. | Front Neurol. 2019 Apr 26;10:433. doi: 10.3389/fneur.2019.00433. eCollection 2019. | Motor Function | Review |
| 31105643 | The effect of electro-acupuncture (MD 9.08, 95% CI [6.81, 11.35]) seems greater in magnitude than manual acupuncture (MD 7.80, 95% CI [6.30, 9.30]) for improving upper limb motor function, however, there was not any direct analysis to compare electro-acupuncture with manual acupuncture in this research. | Front Neurol. 2019 Apr 26;10:433. doi: 10.3389/fneur.2019.00433. eCollection 2019. | Motor Function | Review |
| 31105643 | Results showed that the combination of acupuncture and routine rehabilitation was superior to rehabilitation alone for improving motor function and ADL, and reducing pain. | Front Neurol. 2019 Apr 26;10:433. doi: 10.3389/fneur.2019.00433. eCollection 2019. | Motor Function | Review |
| 31105643 | These will provide a greater certainty of the evidence of acupuncture's effect on motor function. | Front Neurol. 2019 Apr 26;10:433. doi: 10.3389/fneur.2019.00433. eCollection 2019. | Motor Function | Review |
| 31105643 | With regard to how acupuncture helps to improve motor function, experimental studies indicate it may work by enhancing the gamma-aminobutyric acid receptor expression or promoting angiogenesis. | Front Neurol. 2019 Apr 26;10:433. doi: 10.3389/fneur.2019.00433. eCollection 2019. | Motor Function | Review |
| 31105643 | First, we explored the effects of acupuncture for a specific complication (SHS) after stroke, rather than general motor function. | Front Neurol. 2019 Apr 26;10:433. doi: 10.3389/fneur.2019.00433. eCollection 2019. | Motor Function | Review |
| 31105643 | This systematic review shows that adding acupuncture to routine rehabilitation can improve clinical outcomes (pain and motor function) for people with mild post-stroke SHS. | Front Neurol. 2019 Apr 26;10:433. doi: 10.3389/fneur.2019.00433. eCollection 2019. | Motor Function | Review |
| 31139074 | Background: Acupuncture has been reported to have significant effects, not only in alleviating impaired motor function, but also rescuing dopaminergic neuron deficits in rodent models of Parkinson's disease (PD). | Front Aging Neurosci. 2019 May 8;11:102. doi: 10.3389/fnagi.2019.00102. eCollection 2019. | Motor Function | Review |
| 31139074 | In addition, motor dysfunctions exhibited by model PD animals were also mitigated by acupuncture treatment. | Front Aging Neurosci. 2019 May 8;11:102. doi: 10.3389/fnagi.2019.00102. eCollection 2019. | Motor Function | Review |
| 31139074 | In East Asian countries, acupuncture has long been used to treat motor dysfunction and brain disorders such as PD (Joh et al.,). | Front Aging Neurosci. 2019 May 8;11:102. doi: 10.3389/fnagi.2019.00102. eCollection 2019. | Motor Function | Review |
| 31139074 | Moreover, in recent years, it has been shown that acupuncture improves motor function in rodent models of PD via mechanisms including anti-inflammatory and neurotrophic effects (Yu et al.,; Rui et al.,). | Front Aging Neurosci. 2019 May 8;11:102. doi: 10.3389/fnagi.2019.00102. eCollection 2019. | Motor Function | Review |
| 31139074 | Improvement in motor function in PD patients who underwent bee venom acupuncture treatment has been reported (Cho et al.,), and motor function-associated neural responses with acupuncture have also been shown in PD patients using functional magnetic resonance imaging fMRI (Chae et al.,; Yeo et al.,). | Front Aging Neurosci. 2019 May 8;11:102. doi: 10.3389/fnagi.2019.00102. eCollection 2019. | Motor Function | Review |
| 31139074 | Effect of Acupuncture on Motor Function in a PD Model | Front Aging Neurosci. 2019 May 8;11:102. doi: 10.3389/fnagi.2019.00102. eCollection 2019. | Motor Function | Review |
| 31139074 | Table 2 shows how acupuncture affected motor function in PD models by examining the results of behavioral tests. | Front Aging Neurosci. 2019 May 8;11:102. doi: 10.3389/fnagi.2019.00102. eCollection 2019. | Motor Function | Review |
| 31139074 | Based on most studies, it is believed that acupuncture alleviated motor dysfunction in PD rodent models. | Front Aging Neurosci. 2019 May 8;11:102. doi: 10.3389/fnagi.2019.00102. eCollection 2019. | Motor Function | Review |
| 31139074 | Additionally, motor dysfunctions in those PD models were also alleviated by acupuncture. | Front Aging Neurosci. 2019 May 8;11:102. doi: 10.3389/fnagi.2019.00102. eCollection 2019. | Motor Function | Review |
| 31139074 | These results were unexpected because most studies reported that motor dysfunctions in PD animals were significantly altered after acupuncture (Table 2). | Front Aging Neurosci. 2019 May 8;11:102. doi: 10.3389/fnagi.2019.00102. eCollection 2019. | Motor Function | Review |
| 31379957 | Neuroimaging findings of the human brain showed that acupuncture on GB34 and the scalp significantly increased glucose metabolism bilaterally in the frontal and occipital lobes and improved motor dysfunction in patients with PD. | Evid Based Complement Alternat Med. 2019 Jul 11;2019:2909632. doi: 10.1155/2019/2909632. eCollection 2019. | Motor Function | Review |
| 31379957 | Acupuncture induced autophagic clearance of α-syn, caused recovery of DA neurons in the SN, and improved motor function of an animal model without any notable adverse effect. | Evid Based Complement Alternat Med. 2019 Jul 11;2019:2909632. doi: 10.1155/2019/2909632. eCollection 2019. | Adverse Reactions Motor Function | Review |
| 31379957 | In summary, acupuncture improved motor dysfunction and memory of PD. | Evid Based Complement Alternat Med. 2019 Jul 11;2019:2909632. doi: 10.1155/2019/2909632. eCollection 2019. | Motor Function | Review |
| 33029119 | Simultaneously, acupuncture has protective and reparative effects on brain tissue, which can improve the symptoms of cerebral infarct, neurological deficits, and motor function in rats. | Neural Plast. 2020 Sep 22;2020:8850653. doi: 10.1155/2020/8850653. eCollection 2020. | Motor Function | Review |
| 34188677 | Effect of Acupuncture on Neuroplasticity of Stroke Patients with Motor Dysfunction: A Meta-Analysis of fMRI Studies | Neural Plast. 2021 Jun 2;2021:8841720. doi: 10.1155/2021/8841720. eCollection 2021. | Motor Function | Review |
| 34188677 | To analyze the pattern of intrinsic brain activity variability that is altered by acupuncture compared with conventional treatment in stroke patients with motor dysfunction, thus providing the mechanism of stroke treatment by acupuncture. | Neural Plast. 2021 Jun 2;2021:8841720. doi: 10.1155/2021/8841720. eCollection 2021. | Motor Function | Review |
| 34188677 | We only included randomized controlled trials (RCTs) using resting-state fMRI to observe the effect of acupuncture on stroke patients with motor dysfunction. | Neural Plast. 2021 Jun 2;2021:8841720. doi: 10.1155/2021/8841720. eCollection 2021. | Motor Function | Review |
| 34188677 | The results suggest that acupuncture treatment helps the healing process of motor dysfunction in stroke patients and exhibits hyperactivation in the bilateral basal ganglia and insula and hypoactivation in motor-related areas (especially bilateral BA6 and left BA4). | Neural Plast. 2021 Jun 2;2021:8841720. doi: 10.1155/2021/8841720. eCollection 2021. | Motor Function | Review |
| 34188677 | have reported that acupuncture would activate the ipsilateral lesional motor cortex to improve motor function in patients with hemiparetic stroke, while others suggested that the basal ganglia would be predominantly activated by acupuncture. | Neural Plast. 2021 Jun 2;2021:8841720. doi: 10.1155/2021/8841720. eCollection 2021. | Motor Function | Review |
| 34188677 | A greater increase of FMA score (5.73; 95% CI, 4.35 to 7.11; I2 = 77%) also demonstrated that acupuncture could improve motor function of the upper and lower limb. | Neural Plast. 2021 Jun 2;2021:8841720. doi: 10.1155/2021/8841720. eCollection 2021. | Motor Function | Review |
| 34188677 | It is suggested that acupuncture therapy could relieve neurological deficiency (NDS) and improve motor function (FMA) and daily living ability (MBI). | Neural Plast. 2021 Jun 2;2021:8841720. doi: 10.1155/2021/8841720. eCollection 2021. | Motor Function | Review |
| 34188677 | It seems that the damage of the insula is responsible for the motor dysfunction in stroke patients and acupuncture can activate it to exert therapeutic effect. | Neural Plast. 2021 Jun 2;2021:8841720. doi: 10.1155/2021/8841720. eCollection 2021. | Motor Function | Review |
| 34188677 | The meta-analyses of clinical outcome measures (FMA, NDS, BI, or MBI) show that acupuncture treatment is effective for motor function recovery in ischemic stroke patients. | Neural Plast. 2021 Jun 2;2021:8841720. doi: 10.1155/2021/8841720. eCollection 2021. | Motor Function | Review |
| 34446530 | Combined WM treatment with acupuncture instead has a greater effect on improving dependency and motor function than that with CHM. | Stroke Vasc Neurol. 2022 Feb;7(1):77-85. doi: 10.1136/svn-2020-000781. Epub 2021 Aug 26. | Motor Function | Review |
| 34456996 | In addition, the plasticity function of acupuncture on stroke is manifested not only in motor function but also in language. | Neural Plast. 2021 Aug 19;2021:2662585. doi: 10.1155/2021/2662585. eCollection 2021. | Motor Function | Review |
| 34456996 | found that acupuncture improved motor function, brain microscopy using DTI technique. | Neural Plast. 2021 Aug 19;2021:2662585. doi: 10.1155/2021/2662585. eCollection 2021. | Motor Function | Review |
| 34650503 | Abdominal Acupuncture as an Adjunctive Therapy for the Recovery of Motor Function After Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials | Front Neurol. 2021 Sep 28;12:705771. doi: 10.3389/fneur.2021.705771. eCollection 2021. | Motor Function | Review |
| 34840581 | Combined with the results of this study, acupuncture combined with TMS may be the best choice for patients with decreased cognitive function and motor dysfunction after stroke. | Evid Based Complement Alternat Med. 2021 Nov 18;2021:1101101. doi: 10.1155/2021/1101101. eCollection 2021. | Cognitive Function Motor Function | Review |
| 34992414 | The studies mentioned above demonstrate that acupuncture regulates gastrointestinal macrophage polarization and reduces mast cell degranulation, thereby inhibiting the TLR4/MyD88-mediated NF-κB pathway to ultimately regulate production of inflammatory factors and gastrointestinal functional cells such as ICC, and reduce the gastrointestinal inflammatory reaction to restore gastrointestinal motor function. | J Inflamm Res. 2021 Dec 21;14:7191-7224. doi: 10.2147/JIR.S341581. eCollection 2021. | Motor Function | Review |
| 35241146 | In recent years, clinical trials of acupuncture registered and carried out worldwide involve the evaluation of limb motor function, limb spasm and pain, swallowing function, activities of daily living, quality of life, cognitive function, depression, and anxiety state, etc., both in acute and recovery phase of ischemic stroke. | Stem Cell Res Ther. 2022 Mar 3;13(1):87. doi: 10.1186/s13287-022-02761-y. | Cognitive Function Anxiety Depression Motor Function | Review |
| 35449821 | maintained that for stroke patients in the subacute or chronic phase, acupuncture may mitigate neurological deficits, such as motor function, cognitive function, depression, swallowing function, pain, and spasticity. | Evid Based Complement Alternat Med. 2022 Apr 11;2022:7705256. doi: 10.1155/2022/7705256. eCollection 2022. | Cognitive Function Depression Motor Function | Review |
| 35449821 | General scales: (It was concluded that the rehabilitative effects of acupuncture for diseases often involve the following indicators and corresponding scales): (1) Motor function: Fugl-Meyer Assessment Scale (FMA) and Brunnstrom. | Evid Based Complement Alternat Med. 2022 Apr 11;2022:7705256. doi: 10.1155/2022/7705256. eCollection 2022. | Motor Function | Review |
| 35449821 | Currently, acupuncture for motor function and COPD has captured researchers' attention, which might be the futuristic frontier. | Evid Based Complement Alternat Med. 2022 Apr 11;2022:7705256. doi: 10.1155/2022/7705256. eCollection 2022. | Motor Function | Review |
| 35462893 | At the same time, stimulation of GV4 decreases oxidative stress and improves motor function recovery in the hind limbs of rats with paralysis, indicating electroacupuncture at GV4 could be a therapeutic alternative. | Front Pharmacol. 2022 Apr 7;13:875103. doi: 10.3389/fphar.2022.875103. eCollection 2022. | Motor Function | Review |
| 35462893 | Recent studies have observed that electroacupuncture can improve the locomotor function by regulating autophagy flux and inhibiting necroptosis after SCI. | Front Pharmacol. 2022 Apr 7;13:875103. doi: 10.3389/fphar.2022.875103. eCollection 2022. | Motor Function | Review |
| 35462893 | observed that electroacupuncture increases the gene and protein expression of GFAP and the platelet-derived growth factor (PDGF) after spinal cord transection, promoting locomotor function recovery. | Front Pharmacol. 2022 Apr 7;13:875103. doi: 10.3389/fphar.2022.875103. eCollection 2022. | Motor Function | Review |
| 35462893 | Acupuncture alleviates the neurogenic bladder, chronic shoulder pain, neuropathic pain, and osteoporosis and improves neurological (sensory and motor) functions. | Front Pharmacol. 2022 Apr 7;13:875103. doi: 10.3389/fphar.2022.875103. eCollection 2022. | Neuropathic Pain Motor Function | Review |
| 35655620 | Promising effects of TCM interventions in stroke rehabilitation, indicated by statistically significant pooled treatment effects in the SRs (n = 43) and based on a substantial number of research studies, included acupuncture for cognitive impairment, EA for motor dysfunction, CHM for spasticity, and moxibustion for hemiplegia. | Front Neurol. 2022 May 17;13:885095. doi: 10.3389/fneur.2022.885095. eCollection 2022. | Motor Function | Review |
| 35737304 | Acupuncture, particularly EA, has been shown to improve analgesia and accelerate the recovery of motor functions in dogs with intervertebral disc disease (IVDD). | Vet Sci. 2022 May 26;9(6):252. doi: 10.3390/vetsci9060252. | Motor Function | Review |
| 35832139 | Furthermore, it has also been suggested that patients with good motor function at onset who have received acupuncture for at least a month show a greater degree of improvement in their scores in the Beck Depression and HRDS compared to those with severe motor disability. | Psychol Res Behav Manag. 2022 Jul 7;15:1689-1706. doi: 10.2147/PRBM.S310207. eCollection 2022. | Depression Motor Function | Review |
| 35968313 | Studies on cerebral infarction patients and animal models have reported that acupuncture at ST36 improves brain metabolites and memory function and promotes motor function, indicating neural and cognitive recovery promoting the effects of acupuncture. | Front Neurol. 2022 Jul 22;13:930753. doi: 10.3389/fneur.2022.930753. eCollection 2022. | Motor Function | Review |
| 35983251 | The results demonstrate that the treatment of eye acupuncture combined with wax therapy is better compared to simple wax therapy in improving patients' ability of daily life and motor function; (2) the methods of acupuncture can be assigned into two kinds, the first is yin-yang reinforcing and reducing needling, and the second is three tonifying and reducing needling. | Biomed Res Int. 2022 Aug 9;2022:8663356. doi: 10.1155/2022/8663356. eCollection 2022. | Motor Function | Review |
| 36203799 | And acupuncture could have a beneficial effect on neurological and motor function recovery. | Front Neurosci. 2022 Sep 20;16:940343. doi: 10.3389/fnins.2022.940343. eCollection 2022. | Motor Function | Review |
| 36439200 | Four trials in this systematic review and other randomized controlled trials (RCTs) used the Fugl-Meyer Assessment scale (FMI) to evaluate the impact of acupuncture therapy after an ischemic stroke on the motor function of the upper and lower limbs. | Front Cell Neurosci. 2022 Nov 10;16:817732. doi: 10.3389/fncel.2022.817732. eCollection 2022. | Motor Function | Review |
| 36439200 | The results showed greater improvement in motor function in the acupuncture group compared with the non-acupuncture group (Li et al.,; Yang et al.,; Wu J. et al.,). | Front Cell Neurosci. 2022 Nov 10;16:817732. doi: 10.3389/fncel.2022.817732. eCollection 2022. | Motor Function | Review |
| 36439200 | These studies show that acupuncture activated bilateral motor areas of the brain, as well as neural tissues related to motor activity, to promote motor function after ischemic stroke. | Front Cell Neurosci. 2022 Nov 10;16:817732. doi: 10.3389/fncel.2022.817732. eCollection 2022. | Motor Function | Review |
| 36741282 | Meanwhile, we briefly overviewed the research progress of acupuncture in improving motor function after stroke by accelerating neurogenesis. | Front Neurol. 2023 Jan 20;14:1082625. doi: 10.3389/fneur.2023.1082625. eCollection 2023. | Motor Function | Review |
| 36741282 | We hope to emphasize that neurogenesis could be modulated by potential strategies to improve functional outcomes after stroke and explore the feasibility of acupuncture in promoting motor function recovery after stroke. | Front Neurol. 2023 Jan 20;14:1082625. doi: 10.3389/fneur.2023.1082625. eCollection 2023. | Motor Function | Review |
| 36741282 | Electroacupuncture (EA) can improve the symptoms of neurological deficits and promote the recovery of motor function in post-stroke rats. | Front Neurol. 2023 Jan 20;14:1082625. doi: 10.3389/fneur.2023.1082625. eCollection 2023. | Motor Function | Review |
| 36741282 | More and more in-depth studies are worthwhile to enrich the multi-target mechanism of clinical acupuncture for post-stroke motor dysfunction. | Front Neurol. 2023 Jan 20;14:1082625. doi: 10.3389/fneur.2023.1082625. eCollection 2023. | Motor Function | Review |
| 36823586 | Based on the ts-fMRI studies, nine neuroimaging studies reported that the activated brain areas after acupuncture concerned the processing of cognitive function, including the memory regions (e.g., the hippocampus, inferior frontal gyrus, superior frontal gyrus, and superior temporal gyrus), auditory speech area (e.g., the superior temporal gyrus, transverse temporal gyrus, and inferior parietal lobule), language function region (e.g., the middle frontal gyrus, middle temporal gyrus, and cerebellum), spatial attention region (e.g., the superior parietal lobule), affective-emotional processing areas of cognitive function (e.g., the insula, cingulate cortex, and thalamus), motor function region (e.g., the precentral gyrus), and sensory function region (e.g., the postcentral gyrus). | BMC Complement Med Ther. 2023 Feb 23;23(1):63. doi: 10.1186/s12906-023-03888-y. | Cognitive Function Mood Language Function Motor Function | Review |
| 36968499 | There is evidence that acupuncture modulates gastric sensory-motor function, which accounts for its therapeutic effect on some FD patients. | Front Neurosci. 2023 Mar 8;17:1109510. doi: 10.3389/fnins.2023.1109510. eCollection 2023. | Motor Function | Review |
| 37034090 | showed that acupuncture combined with antidepressants improved the depressive status of PSD patients and showed varying degrees of improvement in motor function, activities of daily living, and the degree of neurological deficits in PSD patients. | Front Neurol. 2023 Mar 23;14:979643. doi: 10.3389/fneur.2023.979643. eCollection 2023. | Motor Function | Review |
| 37089473 | As an essential non-pharmacological therapy, acupuncture has long been used for PSS in China and shows favorable effects on improvements of spastic hypertonia and motor function. | Front Public Health. 2023 Apr 6;11:1155372. doi: 10.3389/fpubh.2023.1155372. eCollection 2023. | Motor Function | Review |
| 37089473 | has shown that after 6-months treatment, muscle hypertonia and motor functions were all substantially improved among three treatment groups (rehabilitation alone, rehabilitation after scalp acupuncture and MSSA groups) in comparison with before treatment. | Front Public Health. 2023 Apr 6;11:1155372. doi: 10.3389/fpubh.2023.1155372. eCollection 2023. | Motor Function | Review |
| 37089473 | In MSA, the sensory and motor conduction pathways can be activated simultaneously, owning to the dual of acupuncture manipulation and active/passive body movement, which conduces to restoration of right neural feedback mechanism and reconstruction of motor ability. | Front Public Health. 2023 Apr 6;11:1155372. doi: 10.3389/fpubh.2023.1155372. eCollection 2023. | Motor Function | Review |
| 37229426 | Qualitative and quantitative meta-analysis of acupuncture effects on the motor function of Parkinson's disease patients | Front Neurosci. 2023 May 9;17:1125626. doi: 10.3389/fnins.2023.1125626. eCollection 2023. | Motor Function | Review |
| 37229426 | To explore the association between acupuncture sessions and its effects on the motor function of Parkinson's Disease (PD). | Front Neurosci. 2023 May 9;17:1125626. doi: 10.3389/fnins.2023.1125626. eCollection 2023. | Motor Function | Review |
| 37229426 | Several recently published qualitative meta-analyses suggested that acupuncture-related therapies combined with conventional medication showed a moderate or large effect on movement function in patients with PD (Lee and Lim,; Kwon et al.,; Wen et al.,), and compared with using conventional medication alone, the combination of acupuncture in the treatment of PD, to some extent, can also improve clinical safety (Liu et al.,). | Front Neurosci. 2023 May 9;17:1125626. doi: 10.3389/fnins.2023.1125626. eCollection 2023. | Motor Function | Review |
| 37229426 | Animal experiments have proved that there is a certain scientific basis for acupuncture to improve motor function in PD, such as reducing neuronal apoptosis of the striatum (Lu et al.,), normalizing the brain functional connectivity (Oh et al.,), inhibiting the level of lipid peroxides in dopaminergic neurons and protect neurons from oxidative damage (Zuo et al.,). | Front Neurosci. 2023 May 9;17:1125626. doi: 10.3389/fnins.2023.1125626. eCollection 2023. | Neuroprotection Motor Function | Review |
| 37229426 | The published RCT suggests that more acupuncture sessions lead to greater clinical efficacy in motor function of PD (Li et al.,). | Front Neurosci. 2023 May 9;17:1125626. doi: 10.3389/fnins.2023.1125626. eCollection 2023. | Motor Function | Review |
| 37229426 | However, to the best of our knowledge, there is currently no published systematic review comparing the effect of the number of acupuncture sessions on the efficacy of PD with motor functions. | Front Neurosci. 2023 May 9;17:1125626. doi: 10.3389/fnins.2023.1125626. eCollection 2023. | Motor Function | Review |
| 37275921 | These impairments in BFC showed improvement after acupuncture treatment in the mice model, along with the improvement in motor function and the affeted areas in the brain involving the motor cortex, substantia nigra, and striatum which are closely related to PD pathology. | Integr Med Res. 2023 Jun;12(2):100954. doi: 10.1016/j.imr.2023.100954. Epub 2023 May 11. | Motor Function | Review |
| 37275921 | In patients with PD whose motor function improved after acupuncture intervention at GB34, the putamen and primary motor cortex showed increased activation. | Integr Med Res. 2023 Jun;12(2):100954. doi: 10.1016/j.imr.2023.100954. Epub 2023 May 11. | Motor Function | Review |
| 37275921 | The authors suggested that the effect of acupuncture on motor function may be related to the basal ganglia-thalamocortical circuit. | Integr Med Res. 2023 Jun;12(2):100954. doi: 10.1016/j.imr.2023.100954. Epub 2023 May 11. | Motor Function | Review |
| 37396891 | Considerably more work will need to be done using the scales above to assess postoperative cognitive function recovery of acupuncture combined with sedation, especially psychomotor function. | Front Med (Lausanne). 2023 Jun 16;10:1189429. doi: 10.3389/fmed.2023.1189429. eCollection 2023. | Cognitive Function Motor Function Sedation | Review |
| 37478239 | The effectiveness of acupuncture for patients with PSSP was similar to that of RT on shoulder pain alleviation (standardized mean difference [SMD]: â0.41, 95% confidence interval [CI]: â0.91 to 0.08, P = .10), improvement of upper limb motor function (weighted mean difference [WMD]: 0.80, 95% CI: â1.19 to 2.79, P = .43), and ADL (WMD: â0.83, 95% CI: â3.17 to 1.51, P = .49). | Medicine (Baltimore). 2023 Jul 21;102(29):e34266. doi: 10.1097/MD.0000000000034266. | Motor Function | Review |
| 37478239 | Acupuncture is similar to RT in relieving shoulder pain, improving upper limb motor function and ADL in patients with PSSP. | Medicine (Baltimore). 2023 Jul 21;102(29):e34266. doi: 10.1097/MD.0000000000034266. | Motor Function | Review |
| 37478239 | Therefore, in this study, our aim was to assess the efficacy of acupuncture versus RT on PSSP in terms of pain intensity, upper limb motor function, and activities of daily living (ADL). | Medicine (Baltimore). 2023 Jul 21;102(29):e34266. doi: 10.1097/MD.0000000000034266. | Motor Function | Review |
| 37478239 | There was no significant difference in the efficacy of acupuncture versus RT for improving the upper limb motor function of PSSP patients (WMD: 0.80, 95% CI: â1.19 to 2.79, P = .43) (Fig. | Medicine (Baltimore). 2023 Jul 21;102(29):e34266. doi: 10.1097/MD.0000000000034266. | Motor Function | Review |
| 37478239 | The results of this MA showed that the efficacy of acupuncture for patients with PSSP was similar to that of RT on shoulder pain alleviation, improvement of the upper limb motor function, and ADL. | Medicine (Baltimore). 2023 Jul 21;102(29):e34266. doi: 10.1097/MD.0000000000034266. | Motor Function | Review |
| 37478239 | From this review, our finding indicated acupuncture is similar to RT in reducing shoulder pain, improving upper limb motor function and ADL, but with substantial heterogeneity. | Medicine (Baltimore). 2023 Jul 21;102(29):e34266. doi: 10.1097/MD.0000000000034266. | Motor Function | Review |
| 37478239 | In this review, acupuncture for PSSP is similar to RT in relieving shoulder pain, improving upper limb motor function and ADL. | Medicine (Baltimore). 2023 Jul 21;102(29):e34266. doi: 10.1097/MD.0000000000034266. | Motor Function | Review |
| 37510483 | Additionally, a recent multicenter randomized controlled trial demonstrated that electroacupuncture combined with conventional pharmacological treatment significantly enhances motor function in PD patients. | Healthcare (Basel). 2023 Jul 17;11(14):2042. doi: 10.3390/healthcare11142042. | Motor Function | Review |
| 37510483 | The neural mechanism underlying the effect of acupuncture on the motor function of PD patients has been investigated using functional magnetic resonance imaging (fMRI), which shows that acupuncture stimulation at GB34 acupoint can activate the putamen and primary motor cortex, improving motor function. | Healthcare (Basel). 2023 Jul 17;11(14):2042. doi: 10.3390/healthcare11142042. | Motor Function | Review |
| 37510483 | Our animal studies also support the therapeutic potential of electroacupuncture in PD, demonstrating that electroacupuncture at GB34 and LR3 acupoints promotes motor function recovery and reduces dopaminergic neuron degeneration via Akt-BDNF pathway and autophagy activation in the substantia nigra and striatum, respectively. | Healthcare (Basel). 2023 Jul 17;11(14):2042. doi: 10.3390/healthcare11142042. | Motor Function | Review |
| 38046583 | Multiple acupuncture methods are significantly effective in improving pain and upper limb motor function in post-stroke SHS, with relatively few adverse events; thus, acupuncture can be promoted. | Front Neurol. 2023 Nov 17;14:1268626. doi: 10.3389/fneur.2023.1268626. eCollection 2023. | Motor Function | Review |
| 38046583 | Acupuncture combined with rehabilitation training can significantly help in reducing pain scores, promoting limb motor function recovery, and improving overall effectiveness. | Front Neurol. 2023 Nov 17;14:1268626. doi: 10.3389/fneur.2023.1268626. eCollection 2023. | Motor Function | Review |
| 38046583 | From the results, we found that the combination of acupuncture and rehabilitation is more effective in improving the overall effectiveness of post-stroke SHS than simple rehabilitation intervention, especially in relieving pain and improving motor function. | Front Neurol. 2023 Nov 17;14:1268626. doi: 10.3389/fneur.2023.1268626. eCollection 2023. | Motor Function | Review |
| 38046583 | Most notably, other multi-needle acupuncture combinations and special needle operations and techniques all demonstrate good effects in pain relief and upper limb motor function recovery. | Front Neurol. 2023 Nov 17;14:1268626. doi: 10.3389/fneur.2023.1268626. eCollection 2023. | Pain Relief Motor Function | Review |
| 38046583 | In conclusion, multiple acupuncture treatments have significant effects in treating pain and improving upper limb motor function after a stroke, with fewer adverse events. | Front Neurol. 2023 Nov 17;14:1268626. doi: 10.3389/fneur.2023.1268626. eCollection 2023. | Motor Function | Review |
| 36749304 | The decreased functional activities of SMA may be related to the knee motor dysfunction. | Brain Behav. 2023 Mar;13(3):e2913. doi: 10.1002/brb3.2913. Epub 2023 Feb 7. | Motor Function | Clinic |
| 19041635 | This animal study was designed to determine whether acupuncture improves motor function following experimentally induced cerebral ischemia. | Brain Res. 2009 Jan 12;1248:176-83. doi: 10.1016/j.brainres.2008.11.009. Epub 2008 Nov 13. | Motor Function | Mechanism |
| 19041635 | In addition, we studied whether the outcome of motor function was associated with the expression of BDNF (brain derived neurotrophic factor), trkB (receptor, trkB) and infarct volume. | Brain Res. 2009 Jan 12;1248:176-83. doi: 10.1016/j.brainres.2008.11.009. Epub 2008 Nov 13. | Motor Function | Mechanism |
| 35245503 | Acupuncture alleviates spinal hyperreflexia and motor dysfunction in post-ischemic stroke rats with spastic hypertonia via KCC2-mediated spinal GABA(A) activation. | Exp Neurol. 2022 Aug;354:114027. doi: 10.1016/j.expneurol.2022.114027. Epub 2022 Mar 2. | Motor Function | Mechanism |
| 35245503 | The majority of patients simultaneously develop motor dysfunction and spastic hypertonia after ischemic strokes, which can be associated with an increasing trend in motor impairments, seriously impeding the rehabilitation process. | Exp Neurol. 2022 Aug;354:114027. doi: 10.1016/j.expneurol.2022.114027. Epub 2022 Mar 2. | Motor Function | Mechanism |
| 35245503 | neurologic function scale, muscular tension scale, foot balance test, and gait analysis), H-reflex recording, TTC, Western blotting, RT-qPCR, ELISA, and immunofluorescence molecular assay, the study results illustrated that acupuncture could significantly alleviate the spinal hyperreflexia, decrease muscle tone, and enhance locomotor function by elevating the GABA, KCC2, and GABA(Agamma2) expressions in the lumbar spine of a rat model of post-ischemic stroke with spastic hypertonia. | Exp Neurol. 2022 Aug;354:114027. doi: 10.1016/j.expneurol.2022.114027. Epub 2022 Mar 2. | Immunity Motor Function | Mechanism |
| 31857129 | In the present study, mouse choroid plexus cells were transplanted into ST36 in a mouse model of Parkinson's disease to determine whether the motor function could be restored. | Neurosci Lett. 2020 Jan 19;717:134698. doi: 10.1016/j.neulet.2019.134698. Epub 2019 Dec 16. | Motor Function | Mechanism |
| 31857129 | Pole tests showed changes in motor dysfunction in the mice. | Neurosci Lett. 2020 Jan 19;717:134698. doi: 10.1016/j.neulet.2019.134698. Epub 2019 Dec 16. | Motor Function | Mechanism |
| 34343334 | Electroacupuncture Alleviates Neuroinflammation and Motor Dysfunction by Regulating Intestinal Barrier Function in a Mouse Model of Parkinson Disease. | J Neuropathol Exp Neurol. 2021 Sep 27;80(9):844-855. doi: 10.1093/jnen/nlab046. | Motor Function | Mechanism |
| 34343334 | Electroacupuncture significantly increased the spontaneous activity of mice with PD and increased the expression of tyrosine hydroxylase, while reducing the expression of Iba-1 in substantia nigra (SN), suggesting that motor dysfunction and neurological damage was alleviated. | J Neuropathol Exp Neurol. 2021 Sep 27;80(9):844-855. doi: 10.1093/jnen/nlab046. | Motor Function | Mechanism |
| 20813156 | We evaluated motor function, H(2)S levels and CBS expression in the cerebral cortex and prepared cerebral pathomorphological images after 14 sessions of treatment. | Neurosci Lett. 2010 Nov 12;485(1):74-8. doi: 10.1016/j.neulet.2010.08.068. Epub 2010 Sep 9. | Motor Function | Mechanism |
| 20813156 | EA stimulation could increase local blood circulation and improve motor function in HIBD rats. | Neurosci Lett. 2010 Nov 12;485(1):74-8. doi: 10.1016/j.neulet.2010.08.068. Epub 2010 Sep 9. | Circulation Motor Function | Mechanism |
| 20813156 | Rats with HIBD receiving both EA and HA therapy showed greatly recovered motor function and brain morphology. | Neurosci Lett. 2010 Nov 12;485(1):74-8. doi: 10.1016/j.neulet.2010.08.068. Epub 2010 Sep 9. | Motor Function | Mechanism |
| 21770712 | Phosphatidylinositol 3-kinase/Akt signaling pathway mediates acupuncture-induced dopaminergic neuron protection and motor function improvement in a mouse model of Parkinson's disease. | Int J Neurosci. 2011 Oct;121(10):562-9. doi: 10.3109/00207454.2011.591515. Epub 2011 Jul 19. | Neuroprotection Motor Function | Mechanism |
| 21770712 | Furthermore, we demonstrated for the first time that the brain-specific blockade of phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway, by intranasal administration of LY294002, a specific inhibitor of PI3K/Akt signaling pathway, significantly blocked acupuncture-induced dopaminergic neuron protection and motor function improvement. | Int J Neurosci. 2011 Oct;121(10):562-9. doi: 10.3109/00207454.2011.591515. Epub 2011 Jul 19. | Neuroprotection Motor Function | Mechanism |
| 32827699 | First, we observed that acupuncture treatment at acupoints GB34 and ST36 could improve motor functions and comorbid anxiety in PD mice. | Brain Behav Immun. 2020 Oct;89:641-655. doi: 10.1016/j.bbi.2020.08.015. Epub 2020 Aug 19. | Anxiety Motor Function | Mechanism |
| 32827699 | Of them, Butyricimonas, Holdemania, Frisingicoccus, Gracilibacter, Phocea, and Aestuariispira showed significant correlations with anxiety as well as motor functions. | Brain Behav Immun. 2020 Oct;89:641-655. doi: 10.1016/j.bbi.2020.08.015. Epub 2020 Aug 19. | Anxiety Motor Function | Mechanism |
| 32827699 | In conclusion, we suggest that the effects of acupuncture on the enhanced motor function and the protection of the dopaminergic neurons may be associated with the regulation of the gut microbial dysbiosis and thus the inhibition of the neuroinflammation in the PD mice. | Brain Behav Immun. 2020 Oct;89:641-655. doi: 10.1016/j.bbi.2020.08.015. Epub 2020 Aug 19. | Motor Function | Mechanism |
| 23235115 | Especially, behavioral tests showed that acupuncture stimulations improved the motor dysfunction in a previous study by almost 87.7%. | Gene. 2013 Feb 25;515(2):329-38. doi: 10.1016/j.gene.2012.12.002. Epub 2012 Dec 9. | Motor Function | Mechanism |
| 28392262 | MAIN METHODS: We conducted EA treatment on a rat SCI model produced with a New York University (NYU) Impactor and measured hindlimb locomotor function by Basso, Beattie and Bresnahan Locomotor Rating Scale (BBB Scale). | Life Sci. 2017 May 15;177:8-14. doi: 10.1016/j.lfs.2017.04.004. Epub 2017 Apr 6. | Motor Function | Mechanism |
| 28068836 | Locomotor function, as evaluated by the Basso Mouse Scale score and by catwalk gait parameters, was improved by electro-acupuncture at different time points after injury in parallel with enhanced levels of L1 expression. | Am J Chin Med. 2017;45(1):37-52. doi: 10.1142/S0192415X17500045. Epub 2017 Jan 9. | Motor Function | Mechanism |
| 38189854 | Parkinson's disease (PD) is a neurodegenerative disease that mainly manifests as cognitive decline and motor dysfunction, the treatment of which is still a major challenge in the clinical field. | J Mol Neurosci. 2024 Jan 8;74(1):5. doi: 10.1007/s12031-023-02186-z. | Motor Function | Mechanism |
| 37212035 | Tiaoshen Changzhi acupuncture can improve the behavioral performance of LID rats, reduce abnormal involuntary movement and contralateral rotation behavior and enhance the motor function of the left forelimb of rats. | Biotechnol Genet Eng Rev. 2023 May 22:1-15. doi: 10.1080/02648725.2023.2204694. | Motor Function | Mechanism |
| 28687422 | CONCLUSION: EA at ST 36 and LI 11 could enhance the neural activity of motor function-related brain regions, including motor cortex, dorsal thalamus, and striatum in rats, which is a potential treatment for ischemia stroke. | J Stroke Cerebrovasc Dis. 2017 Sep;26(9):1953-1959. doi: 10.1016/j.jstrokecerebrovasdis.2017.06.018. Epub 2017 Jul 4. | Motor Function | Mechanism |
| 37548586 | Motor function of rats before and after intervention. | Brain Behav. 2023 Oct;13(10):e3177. doi: 10.1002/brb3.3177. Epub 2023 Aug 7. | Motor Function | Mechanism |
| 37435647 | Studies have confirmed that CRH in the central nucleus affects the motor function of the peripheral gastrointestinal tract through the autonomic nervous pathway. | J Neurophysiol. 2023 Aug 1;130(2):380-391. doi: 10.1152/jn.00156.2023. Epub 2023 Jul 12. | Gastrointestinal Tract Motor Function | Mechanism |
| 26184310 | We examined the effect of repetitive DBV stimulation on SCI-induced bilateral pain behaviors, glia expression and motor function recovery. | Toxins (Basel). 2015 Jul 10;7(7):2571-85. doi: 10.3390/toxins7072571. | Motor Function | Mechanism |
| 26184310 | These results indicate that the repetitive application of DBV during the induction phase not only decreased neuropathic pain behavior and glia expression, but also enhanced locomotor functional recovery after SCI. | Toxins (Basel). 2015 Jul 10;7(7):2571-85. doi: 10.3390/toxins7072571. | Neuropathic Pain Motor Function | Mechanism |
| 26184310 | Thus, the present study was designed to examine the following: (1) whether repetitive DBV acupuncture point treatment for five days during the induction and maintenance phases following thoracic 13 (T13) spinal cord hemisection would produce a more potent and prolonged analgesic effect compared to controls that received repetitive injections of vehicle; (2) whether the anti-nociceptive effect of DBV is mediated by the modulation of spinal astrocyte and microglia activation; and (3) whether repetitive DBV treatment affects motor functional recovery in SCI rats. | Toxins (Basel). 2015 Jul 10;7(7):2571-85. doi: 10.3390/toxins7072571. | Analgesic Effect Motor Function | Mechanism |
| 26184310 | Effect of Repetitive DBV Treatment on Motor Function Recovery after Spinal Cord Injury | Toxins (Basel). 2015 Jul 10;7(7):2571-85. doi: 10.3390/toxins7072571. | Motor Function | Mechanism |
| 26184310 | Graphs illustrating the effects of repetitive DBV or vehicle treatment during the induction phase on the recovery of motor function in SCI rats. | Toxins (Basel). 2015 Jul 10;7(7):2571-85. doi: 10.3390/toxins7072571. | Motor Function | Mechanism |
| 26184310 | Because the ipsilateral hindlimb was operated on in the hemisection model, we only recorded the motility of the ipsilateral hindlimb based on the locomotor rating set by Basso et al.. Repetitive DBV treatment during the induction phase evoked a significant and rapid recovery of motor function. | Toxins (Basel). 2015 Jul 10;7(7):2571-85. doi: 10.3390/toxins7072571. | Motor Function | Mechanism |
| 26184310 | Thus, early repetitive DBV treatment presents the advantage of motor function recovery, because DBV-treated rats appeared to present facilitated motor functional recovery from Day 3 after SCI. | Toxins (Basel). 2015 Jul 10;7(7):2571-85. doi: 10.3390/toxins7072571. | Motor Function | Mechanism |
| 26184310 | The demyelination of axons in the injured spinal cord is a known cause of motor function deficits, and remyelination or regeneration by natural formation are extremely limited due to glial scarring and growth inhibitors contained in the environment. | Toxins (Basel). 2015 Jul 10;7(7):2571-85. doi: 10.3390/toxins7072571. | Motor Function | Mechanism |
| 26184310 | Therefore, the DBV-induced constant chemical stimulation at an acupuncture point may have facilitated locomotor function recovery. | Toxins (Basel). 2015 Jul 10;7(7):2571-85. doi: 10.3390/toxins7072571. | Motor Function | Mechanism |
| 26184310 | Collectively, we suggest that the repetitive DBV treatment during the induction phase can facilitate motor function recovery by enhancing sensory stimulation and by suppressing secondary injury development. | Toxins (Basel). 2015 Jul 10;7(7):2571-85. doi: 10.3390/toxins7072571. | Motor Function | Mechanism |
| 26184310 | In addition, the facilitation of motor function recovery occurred by repetitive DBV treatment. | Toxins (Basel). 2015 Jul 10;7(7):2571-85. doi: 10.3390/toxins7072571. | Motor Function | Mechanism |
| 26184310 | Motor Function Recovery | Toxins (Basel). 2015 Jul 10;7(7):2571-85. doi: 10.3390/toxins7072571. | Motor Function | Mechanism |
| 26184310 | After the rats underwent spinal cord hemisection surgery, they were tested for motor function or coordination in an open-field test space using the BBB locomotor rating scale. | Toxins (Basel). 2015 Jul 10;7(7):2571-85. doi: 10.3390/toxins7072571. | Motor Function | Mechanism |
| 26184310 | Only the scores of the ipsilateral hind limb on the hemisected side were examined, because there was no significant difference in locomotor function of the contralateral hind limb. | Toxins (Basel). 2015 Jul 10;7(7):2571-85. doi: 10.3390/toxins7072571. | Motor Function | Mechanism |
| 26016857 | An experimental α-syn-inducible transgenic mouse, in which PD-related A53T mutant α-syn is selectively expressed in astrocytes, developed an early-onset, rapidly progressed movement disability. | J Neuroinflammation. 2015 May 28;12:103. doi: 10.1186/s12974-015-0302-z. | Motor Function | Mechanism |
| 26016857 | EA delayed the early onset of movement disability in A53T mice | J Neuroinflammation. 2015 May 28;12:103. doi: 10.1186/s12974-015-0302-z. | Motor Function | Mechanism |
| 26016857 | EA improved motor function in A53T mice. | J Neuroinflammation. 2015 May 28;12:103. doi: 10.1186/s12974-015-0302-z. | Motor Function | Mechanism |
| 26016857 | After 2 months of age, A53T mice showed an acceleration of the motor disability. | J Neuroinflammation. 2015 May 28;12:103. doi: 10.1186/s12974-015-0302-z. | Motor Function | Mechanism |
| 26016857 | The acceleration of the motor disability after 2 months might be due to substantial expression of α-syn in astrocytes. | J Neuroinflammation. 2015 May 28;12:103. doi: 10.1186/s12974-015-0302-z. | Motor Function | Mechanism |
| 26016857 | EA modulated α-syn pathology and alleviated motor disability in A53T mice | J Neuroinflammation. 2015 May 28;12:103. doi: 10.1186/s12974-015-0302-z. | Motor Function | Mechanism |
| 26016857 | Activated microglia then trigger the loss of neuron, which may contribute to the movement disability. | J Neuroinflammation. 2015 May 28;12:103. doi: 10.1186/s12974-015-0302-z. | Motor Function | Mechanism |
| 30089868 | The SPS-induced groups displayed little variation in swimming time, indicating that the above results are caused by depression-like behavior, not by motor function deficits (Fig. 3D). | Sci Rep. 2018 Aug 8;8(1):11864. doi: 10.1038/s41598-018-30337-5. | Depression Motor Function | Mechanism |
| 21625423 | Because the abnormal motor function in PD is mainly caused by subthreshold levels of DA in the striatum, we looked at the concentration of striatal DA and its metabolites, DOPAC and HVA in our different groups. | PLoS One. 2011;6(5):e19790. doi: 10.1371/journal.pone.0019790. Epub 2011 May 23. | Motor Function | Mechanism |
| 26792101 | Further, we observed the recovery in the activity of dopaminergic neurons in SNpc, and improvement in the motor function at the behavior level of PD mice. | Sci Rep. 2016 Jan 21;6:19714. doi: 10.1038/srep19714. | Motor Function | Mechanism |
| 26792101 | Concomitantly, we observed PD-like pathological changes including motor dysfunction and dopamine (DA) neuron impairment in SNpc of PG mice. | Sci Rep. 2016 Jan 21;6:19714. doi: 10.1038/srep19714. | Motor Function | Mechanism |
| 26792101 | Stimulation of Yanglingquan (GB34), which is located at the depression anterior and inferior to the fibular head, is traditionally used for the motor function treatment in TCM. | Sci Rep. 2016 Jan 21;6:19714. doi: 10.1038/srep19714. | Depression Motor Function | Mechanism |
| 26792101 | Having substantiated the acupuncture-induced autophagic clearance of α-syn, we next examined the therapeutic effect of acupuncture on the motor function, the number and the activity of DA neurons in mice of PG. | Sci Rep. 2016 Jan 21;6:19714. doi: 10.1038/srep19714. | Motor Function | Mechanism |
| 26792101 | In order to quantify their motor function, we measured the overall rod performance (ORP) score using a rota rod instrument (Fig. | Sci Rep. 2016 Jan 21;6:19714. doi: 10.1038/srep19714. | Motor Function | Mechanism |
| 26792101 | This molecular level change results in the recovery of DA neurons at organ level and the improvement of motor function at behavior level. | Sci Rep. 2016 Jan 21;6:19714. doi: 10.1038/srep19714. | Motor Function | Mechanism |
| 26792101 | The effects of autophagic clearance of α-syn, protection of DA neuron and improvement in motor function in rapamycin-treated PD mice can be effectively replicated with acupuncture (Fig. | Sci Rep. 2016 Jan 21;6:19714. doi: 10.1038/srep19714. | Motor Function | Mechanism |
| 22132113 | Acupuncture Enhances the Synaptic Dopamine Availability to Improve Motor Function in a Mouse Model of Parkinson's Disease | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | We found that acupuncture treatment at acupoint GB34 improved motor function with accompanying dopaminergic neuron protection against MPTP but did not restore striatal dopamine depletion. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Neuroprotection Motor Function | Mechanism |
| 22132113 | These results suggest that the acupuncture-induced enhancement of synaptic dopamine availability may play a critical role in motor function improvement against MPTP. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | However, the underlying mechanisms of acupuncture on the improvement of motor dysfunction in PD models are not well understood. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | Given the critical role of dopamine and the importance in the neuroplasticity of the impaired basal ganglia on regulating motor function in PD, we hypothesized that acupuncture improves the motor deficits by modulating dopaminergic neurotransmission in the striatum, and thus ameliorating the abnormal postsynaptic changes induced by dopamine depletion in mouse Parkinsonian model. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | Thus, in the present study, we compared the effects of acupuncture on the motor function and dopaminergic neuron survival with sham acupuncture (the same acupuncture stimulation was given to a control point) in mouse Parkinsonian model. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | Acupoint GB34 has been used to treat movement disorders in traditional East Asian medicine, and also studied on the relation with motor function in recent neuroimaging studies. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | Acupuncture treatment at GB34 improved motor function and prevented dopaminergic neuron degeneration against MPTP | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | Acupuncture treatment at GB34 induced a significant improvement of motor function against MPTP, whereas acupuncture treatment at the control point had no effect. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | Also, acupuncture treatment at GB34 significantly improved motor function against MPTP. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | These results demonstrate that acupuncture treatment at a specific acupoint (GB34), but not at a control point, significantly alleviated MPTP-induced motor dysfunction and dopaminergic neuron degeneration. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | Since acupuncture treatment improved motor function (Fig. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | The present study demonstrates that acupuncture treatment improved motor function against MPTP most likely through an enhancement of dopamine availability in the synaptic cleft rather than the restoration of the levels of total striatal dopamine. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | We found that only acupuncture treatment at GB34, but not at control point significantly improved motor function and prevented dopaminergic neuron degeneration against MPTP (Fig. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | We also found that acupuncture treatment at GB34 alleviated MPTP-induced motor dysfunction and dopaminergic neuron degeneration, and increased dopamine turnover ratios but did not restore the levels of total striatal dopamine (Figs. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | Some studies displayed that MPTP administration increased the dopamine turnover ratio as a compensatory mechanism with the impairment of motor function. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | However, the animals with the improvement of motor function after acupuncture enhanced dopamine turnover ratios much more significantly than MPTP group. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | Recently, we reported that acupuncture can restore MPTP-induced impairment of phosphatidylinositol 3-kinase (PI3K)/Akt cell survival pathway, and PI3K/Akt signalling mediates both acupuncture-induced dopaminergic neuron protection and motor function improvement. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Neuroprotection Motor Function | Mechanism |
| 22132113 | Given LY294002, a specific inhibitor of PI3K, concomitantly blocked both acupuncture-induced dopaminergic neuron protection and motor function improvement, there seems to be a strong correlation between acupuncture-induced neuroprotection and motor function improvement. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Neuroprotection Motor Function | Mechanism |
| 22132113 | 2, 3, 4) results raise one possibility that the acupuncture-induced dopaminergic neuronal protection may lead to increase in dopamine efflux from the surviving dopaminergic neurons, which in turn may result in improved motor function without necessitating restoration of the striatal dopamine content. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Neuroprotection Motor Function | Mechanism |
| 22132113 | There are several studies suggesting that the striatal dopamine content is not necessarily correlated with the improvement of motor function. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | However, whether the changes in DAT density participate in the improvement of motor function needs further investigation. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | Taken together, our results suggest that acupuncture treatment at GB34 ameliorates MPTP-induced motor dysfunction most likely through an enhancement of dopamine availability in the synaptic cleft rather than the restoration of the levels of total striatal dopamine. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | The basal ganglia output structure also may participate in the improvement of motor function induced by acupuncture as Jia et al. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | In conclusion, our results suggest that increased dopamine release after acupuncture treatment at GB34 may lead to an enhancement of dopamine availability in the synaptic cleft that in turn, may play an essential role in motor function improvement against MPTP (Fig. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | Our finding that acupuncture improved motor function without necessitating striatal dopamine refilling suggests that acupuncture treatment can be complementary to dopamine replacement therapy. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | Striatal dopamine depletion caused by MPTP-induced dopaminergic denervation leads to abnormally high levels of Thr34-phosphorylated DARPP-32 and the consequent upregulation of FosB in the striatum, which, in turn, may result in abnormal motor function (B). | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 22132113 | Therefore, we propose that acupuncture treatment at GB34 improved motor function against MPTP most likely through an enhancement of dopamine availability in the synaptic cleft. | PLoS One. 2011;6(11):e27566. doi: 10.1371/journal.pone.0027566. Epub 2011 Nov 22. | Motor Function | Mechanism |
| 24321617 | To test motor function and dyskinetic anomalies, we examined cylinder behaviour and abnormal involuntary movement (AIM), respectively. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | We found that (1) a 50% reduced dose of l-dopa (7.5 mg/kg) combined with acupuncture showed an improvement in motor function that was comparable to mice given the standard dose of l-dopa treatment (15 mg/kg) only, and that (2) the combination treatment (l-dopa +acupuncture) was significantly superior in reducing AIM scores when equivalent doses of l-dopa were used. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | All of these results indicate that acupuncture enhances the benefits of l-dopa on motor function with reduced dose of l-dopa and alleviating LID by normalising neurochemical imbalance within the basal ganglia. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | This characteristic of PD disrupts the balance of the basal ganglia circuit and subsequently disrupts motor functions, leading to rigidity, tremor, and akinesia. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | Because it results in a dramatic improvement in motor function in the early stages of the disease, administration of the dopamine precursor l-dopa is currently one of the gold standards for PD treatment. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | In our previous research, acupuncture improved the motor function of a PD mouse model by increasing the dopamine efflux and turnover ratio of dopamine. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | In this study, we investigated whether this combined treatment improves motor function in 6-OHDA-induced PD mice and simultaneously alleviates LID. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | Therefore, we can conclude that this motor function improvement by acupuncture is not consequent of abnormal involuntary movement (Fig. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | The results in PD mice also suggested the acupoint GB34 is the most effective for improving motor function. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | Next, we sought to determine whether the acupuncture and l-dopa combination therapy lowered the effective dose of l-dopa and improved motor function. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | In cylinder tests designed to check motor functions, the 6-OHDA-induced PD mice showed significantly decreased forelimb contact with the cylinder wall relative to normal control mice. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | Mice that received the combination treatment showed motor function improvement that matched the normal control mice and the mice receiving purely the double dose of l-dopa. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | In other words, the combination therapy reduced the effective dose of l-dopa necessary to improve motor function without inducing the severe LID that a double dose of l-dopa would have otherwise produced. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | The basal ganglia system is known to be involved in numerous neurological systems, including motor function, habit learning, reinforcement, and addiction; the primary role of the basal ganglia is to relay cortical signals and, accordingly, to modify brain function. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | The administration of low-dose l-dopa in conjunction with acupuncture potentiates motor function improvement without the onset of adverse effects such as LID. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Adverse Reactions Motor Function | Mechanism |
| 24321617 | Five doses of l-dopa were used (0, 5, 10, 15, and 20 mg/kg) to construct a dose-dependent curve of motor function. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | After the injection with or without acupuncture treatment 10 days more, AIM were scored for test the side effect in addition to motor function improvement by same treatment. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Side Effects Motor Function | Mechanism |
| 24321617 | To test dose-responsed motor function resulting from treatment with l-dopa with or without acupuncture, the mice were given a rotational test on the first treatment day. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | Acupuncture point GB34 has been used to treat movement disorders in traditional East Asian medicine, and recent neuroimaging studies also discuss its effects on motor function. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | Dose-responsed motor function curve and abnormal involuntary movement (AIM) scoring relating l-dopa dosage with or without acupuncture. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24321617 | If necessary, behavioural tests were performed on day 22 to examine the dose-response motor function. | Brain Res. 2014 Jan 28;1544:33-44. doi: 10.1016/j.brainres.2013.11.028. Epub 2013 Dec 7. | Motor Function | Mechanism |
| 24524846 | GB34 is known to have an effect on pain and motor dysfunction. | J Pain. 2014 May;15(5):535-49. doi: 10.1016/j.jpain.2014.01.498. Epub 2014 Feb 10. | Motor Function | Mechanism |
| 31600836 | Besides involvement in motor functions, these two nuclei also play a role in the regulation of emotional behavior, cognition, and autonomic functions. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Mood Motor Function | Mechanism |
| 21695393 | EA inhibition of CPA in this model is not due to a motor disorder: saline-injected rats given EA treatment showed no avoidance or preference to either of two compartments, indicating that EA treatment does not disrupt motor ability in rats. | Neurochem Res. 2011 Nov;36(11):2104-10. doi: 10.1007/s11064-011-0534-y. Epub 2011 Jun 22. | Motor Function | Mechanism |
| 22524543 | Increased withdrawal latency in the thermal assay was not due to motor impairment, as the same dose of hPAP did not affect motor function in the rotarod test (Figure 2C). | Mol Pain. 2012 Apr 23;8:28. doi: 10.1186/1744-8069-8-28. | Motor Function | Mechanism |
| 22524543 | Motor function was measured by the rotarod performance test (cutoff time of 300 s). | Mol Pain. 2012 Apr 23;8:28. doi: 10.1186/1744-8069-8-28. | Motor Function | Mechanism |
| 28913350 | demonstrated that EA treatment improves the motor functions of the limbs and the activities of daily living in patients with hemiplegia caused by acute cerebral infarction; they also noted that this effect was associated with reduced serum levels of neuron-specific enolase, soluble protein-100B, and endothelin. | Biomed Res Int. 2017;2017:3178014. doi: 10.1155/2017/3178014. Epub 2017 Aug 24. | Motor Function | Mechanism |
| 28913350 | Notably, EA at the Baihui acupoint may facilitate the recovery of motor function and stimulate brain-derived neurotrophic factor (BDNF) and receptor tyrosine kinase B expression in rats with cerebral ischemia. | Biomed Res Int. 2017;2017:3178014. doi: 10.1155/2017/3178014. Epub 2017 Aug 24. | Motor Function | Mechanism |
| 38026466 | Nissl bodies of neurons in the anterior horn of the spinal cord could be sporadically distributed and small in shape, on the 14th day after operation, which is speculated to be related to the impairment of motor function of the forelimbs. | J Pain Res. 2023 Nov 20;16:3945-3960. doi: 10.2147/JPR.S419927. eCollection 2023. | Motor Function | Mechanism |
| 34782576 | A large number of animal experiments have shown that acupuncture at GV20 and GV14 can reduce excitotoxicity, enhance neurogenesis, and promote the release of neurotrophic factors in the brain (e.g., brain-derived neurotrophic factor, nuclear factor kappa B, tropomyosin-related kinase B), which reduces cerebral infarct volume and improves sensorimotor function (Cheng et al., 2014; Kim et al., 2014; Wang et al., 2014; Chang et al., 2018; Park et al., 2019). | Neural Regen Res. 2022 Jun;17(6):1310-1317. doi: 10.4103/1673-5374.327355. | Toxic Side Effects Motor Function | Mechanism |
| 34782576 | Previous studies have revealed the importance of S1 in motor function (Pavlides et al., 1993; Vidoni et al., 2010; Mathis et al., 2017) and have shown that M1 receives strong input from S1 (Petrof et al., 2015; Kinnischtzke et al., 2016). | Neural Regen Res. 2022 Jun;17(6):1310-1317. doi: 10.4103/1673-5374.327355. | Motor Function | Mechanism |
| 34782576 | Accumulating evidence indicates that somatosensory function impairment may be a major contributor to motor dysfunction in several disorders, including stroke, dystonia, and ataxia (Hiraba et al., 2000). | Neural Regen Res. 2022 Jun;17(6):1310-1317. doi: 10.4103/1673-5374.327355. | Motor Function | Mechanism |
| 25206406 | In addition, Ca2+ fluctuation, homeostasis, and vasomotor function adjustment mechanism may also be associated with endogenous neuroprotective effects. | Neural Regen Res. 2013 Apr 25;8(12):1122-31. doi: 10.3969/j.issn.1673-5374.2013.12.007. | Neuroprotection Motor Function | Mechanism |
| 36440366 | This axonal sprouting enters the part of the cervical medulla that has lost corticospinal projections from the stroke-affected region and promotes recovery of motor function. | Biomed Res Int. 2022 Nov 14;2022:3470685. doi: 10.1155/2022/3470685. eCollection 2022. | Motor Function | Mechanism |
| 36440366 | These results show that EA after p-MCAO increases the expression of GAP-43 and SYN in the contralateral cerebral cortex, suggesting that EA intervention after p-MCAO can help drive motor function recovery by enhancing neuroplasticity. | Biomed Res Int. 2022 Nov 14;2022:3470685. doi: 10.1155/2022/3470685. eCollection 2022. | Motor Function | Mechanism |
| 25861363 | Researches have found that acupuncture can effectively improve the motor function of ischemic stroke patients, possibly due to the improvement of cerebral circulation, but the underlying biological mechanisms of acupuncture effects are still poorly understood and need to be further explored. | Evid Based Complement Alternat Med. 2015;2015:496932. doi: 10.1155/2015/496932. Epub 2015 Mar 10. | Circulation Motor Function | Mechanism |
| 28806763 | It is known that ST36 or/and ST44 stimulation excite(s) parasympathetic nerve, however, these conclusions are mainly drew from anesthetized animals, and they were focused on intestinal motor function and electrophysiology. | PLoS One. 2017 Aug 14;12(8):e0181948. doi: 10.1371/journal.pone.0181948. eCollection 2017. | Motor Function | Mechanism |
| 33328963 | In addition, among the five groups, there was no significant time effect (F[4, 140] = 1.198, p = 0.315), treatment effect (F[4, 35] = 0.019, p > 0.05), or interaction of time and treatment (F[16, 140], p > 0.05) in swimming speed (Figure 1G), suggesting no effect on motor function. | Front Aging Neurosci. 2020 Nov 23;12:582904. doi: 10.3389/fnagi.2020.582904. eCollection 2020. | Motor Function | Mechanism |
| 37128191 | Effect of EA on MPTP-induced motor dysfunction | J Tradit Complement Med. 2023 Jan 11;13(3):263-269. doi: 10.1016/j.jtcme.2023.01.005. eCollection 2023 May. | Motor Function | Mechanism |
| 37128191 | Based on the results of the pole test (A) and rotarod test (B), EA at GB34 alleviates MPTP-induced motor dysfunction. | J Tradit Complement Med. 2023 Jan 11;13(3):263-269. doi: 10.1016/j.jtcme.2023.01.005. eCollection 2023 May. | Motor Function | Mechanism |
| 29623942 | To eliminate sensory, visual or motor dysfunction effects on spatial learning and memory abilities, a 1-day visual platform trial was used. | Neural Regen Res. 2018 Mar;13(3):541-548. doi: 10.4103/1673-5374.228760. | Learning and Memory Ability Motor Function | Mechanism |
| 29623942 | Morris water maze visible platform trials indicated that differences in sensory, visual or motor functions did not significantly affect spatial learning or memory. | Neural Regen Res. 2018 Mar;13(3):541-548. doi: 10.4103/1673-5374.228760. | Learning and Memory Ability Motor Function | Mechanism |
| 24527041 | There was no effect on swimming time in the FST, which confirms that the antidepressant-like activity was not caused by a motor function deficit. | Evid Based Complement Alternat Med. 2014;2014:216503. doi: 10.1155/2014/216503. Epub 2014 Jan 9. | Motor Function | Mechanism |
| 25206727 | Physiological sensations from the gastrointestinal tract are transferred to the central nervous system via the vagus nerve allowing adjustment of gastrointestinal secretory and motor functions. | Neural Regen Res. 2013 Mar 25;8(9):802-8. doi: 10.3969/j.issn.1673-5374.2013.09.004. | Gastrointestinal Tract Motor Function | Mechanism |
| 28837077 | EA 0 Hz stimulation at the GB34 and LR3 acupoints had no effect upon motor dysfunction and dopaminergic neurodegeneration in MPTP mice (Figure 1). | Int J Mol Sci. 2017 Aug 24;18(9):1846. doi: 10.3390/ijms18091846. | Motor Function | Mechanism |
| 28837077 | This was accompanied by significant improvement of motor function, in finger-tapping tasks of the affected hand following acupuncture. | Int J Mol Sci. 2017 Aug 24;18(9):1846. doi: 10.3390/ijms18091846. | Motor Function | Mechanism |
| 25983633 | Not surprisingly, gross movement dysfunction caused by damage to this area is a symptom of PD. | Genet Mol Biol. 2015 Mar;38(1):115-27. doi: 10.1590/S1415-475738120140137. Epub 2014 Mar 17. | Motor Function | Mechanism |
| 25983633 | Using a 6-hydroxydopamine (6-OHDA)-induced Parkinsonism model, a previous study found that acupuncture stimulation at acupoints GB34 and LR3 results in the enhanced survival of dopaminergic neurons in the SN and a â¼87.7% improvement in motor dysfunction. | Genet Mol Biol. 2015 Mar;38(1):115-27. doi: 10.1590/S1415-475738120140137. Epub 2014 Mar 17. | Motor Function | Mechanism |
| 25983633 | Similar finding were found following the administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), where the acupuncture-induced enhancement of synaptic dopamine availability may play a critical role in the observed motor function improvement. | Genet Mol Biol. 2015 Mar;38(1):115-27. doi: 10.1590/S1415-475738120140137. Epub 2014 Mar 17. | Motor Function | Mechanism |
| 25983633 | Behavioral tests demonstrated that acupuncture stimulation improves motor dysfunction in a 6-OHDA Parkinsonism model by â¼87.7% . | Genet Mol Biol. 2015 Mar;38(1):115-27. doi: 10.1590/S1415-475738120140137. Epub 2014 Mar 17. | Motor Function | Mechanism |
| 25983633 | Further studies of the association between gene expression and motor function following acupuncture are warranted, as the investigated genes may mediate the protective effects of acupuncture on SN-mediated motor function. | Genet Mol Biol. 2015 Mar;38(1):115-27. doi: 10.1590/S1415-475738120140137. Epub 2014 Mar 17. | Motor Function | Mechanism |
| 35251208 | To determine whether the SPS-induced cognitive memory and spatial memory impairments in rats were clearly linked to a decrease in movement caused by motor dysfunction, we assessed locomotor activity in all rats in the OFT; the results showed no significant differences among groups. | Evid Based Complement Alternat Med. 2022 Feb 23;2022:4430484. doi: 10.1155/2022/4430484. eCollection 2022. | Motor Function | Mechanism |
| 26889195 | Consequently, promoting the recovery of motor function below the site of injury has been the focus of numerous recent studies (Zhang et al., 2014). | Neural Regen Res. 2015 Dec;10(12):2033-9. doi: 10.4103/1673-5374.172323. | Motor Function | Mechanism |
| 26889195 | Acupuncture has been shown to lessen the inflammatory reaction after acute SCI and alleviate secondary injury to the spinal cord, thereby improving sensory and motor dysfunction following SCI. | Neural Regen Res. 2015 Dec;10(12):2033-9. doi: 10.4103/1673-5374.172323. | Motor Function | Mechanism |
| 26889195 | After SCI, the recovery of motor function depends on the capacity of the nervous system to repair itself, and on the preservation of motor end plate integrity. | Neural Regen Res. 2015 Dec;10(12):2033-9. doi: 10.4103/1673-5374.172323. | Motor Function | Mechanism |
| 26889195 | In the present study, we examined AChE activity, Nissl bodies, GDNF mRNA expression, and the motor function of the lower extremities in a rat model of SCI after electroacupuncture. | Neural Regen Res. 2015 Dec;10(12):2033-9. doi: 10.4103/1673-5374.172323. | Motor Function | Mechanism |
| 26889195 | For the BBB locomotor rating scale, motor function was classified into 22 grades as follows: 0 = complete paralysis; 21 = normal function. | Neural Regen Res. 2015 Dec;10(12):2033-9. doi: 10.4103/1673-5374.172323. | Motor Function | Mechanism |
| 26889195 | Effects of electroacupuncture on the hindlimb motor function of rats with SCI | Neural Regen Res. 2015 Dec;10(12):2033-9. doi: 10.4103/1673-5374.172323. | Motor Function | Mechanism |
| 26889195 | The BBB score and the critical angle of the inclined board were higher in the electroacupuncture group at the various time points compared with the control group, which demonstrates that electroacupuncture contributes to the recovery of hind limb motor function. | Neural Regen Res. 2015 Dec;10(12):2033-9. doi: 10.4103/1673-5374.172323. | Motor Function | Mechanism |
| 26889195 | BBB scores showed an improvement in motor function, which suggests that GDNF may protect nerve cells and promote nerve repair and regeneration. | Neural Regen Res. 2015 Dec;10(12):2033-9. doi: 10.4103/1673-5374.172323. | Motor Function | Mechanism |
| 26889195 | Taken together, our findings suggest that increased GDNF mRNA expression and increased AChE activity play important roles in the recovery of motor function. | Neural Regen Res. 2015 Dec;10(12):2033-9. doi: 10.4103/1673-5374.172323. | Motor Function | Mechanism |
| 30505267 | Electroacupuncture Restores Locomotor Functions After Mouse Spinal Cord Injury in Correlation With Reduction of PTEN and p53 Expression | Front Mol Neurosci. 2018 Nov 16;11:411. doi: 10.3389/fnmol.2018.00411. eCollection 2018. | Motor Function | Mechanism |
| 30505267 | Previous studies indicated that EA not only improves locomotor function after SCI as assayed by behavioral studies (Wei et al.,), but also enhances expression of trophic molecules (Mo et al.,; Fang et al.,; Min et al.,; Wei et al.,; Zhao J. et al.,). | Front Mol Neurosci. 2018 Nov 16;11:411. doi: 10.3389/fnmol.2018.00411. eCollection 2018. | Motor Function | Mechanism |
| 30505267 | AP and EA Promote Locomotor Functions of Mice After SCI | Front Mol Neurosci. 2018 Nov 16;11:411. doi: 10.3389/fnmol.2018.00411. eCollection 2018. | Motor Function | Mechanism |
| 30505267 | To determine the effect of EA and AP on locomotor function after SCI in the mouse, the BMS score and subscore were evaluated at 1, 3, 7, 14 and 28 days after SCI. | Front Mol Neurosci. 2018 Nov 16;11:411. doi: 10.3389/fnmol.2018.00411. eCollection 2018. | Motor Function | Mechanism |
| 31871478 | The results showed that the combined treatment had a synergistic effect on improvements in abnormal motor function and neurodegeneration compared with the use of acupuncture or herbal medicine alone. | Evid Based Complement Alternat Med. 2019 Nov 21;2019:3612587. doi: 10.1155/2019/3612587. eCollection 2019. | Motor Function | Mechanism |
| 31871478 | The modified form of Chunggantang (KD5040) is widely used in Traditional Oriental Medicine and has many effects, including anti-inflammatory and neuroprotective properties, improvement of motor function, decreasing the dose of levodopa, and relieving LID. | Evid Based Complement Alternat Med. 2019 Nov 21;2019:3612587. doi: 10.1155/2019/3612587. eCollection 2019. | Neuroprotection Motor Function | Mechanism |
| 31871478 | Motor Function Test | Evid Based Complement Alternat Med. 2019 Nov 21;2019:3612587. doi: 10.1155/2019/3612587. eCollection 2019. | Motor Function | Mechanism |
| 31871478 | Effect of KD5040 on Motor Function Tests to Determine the Suboptimal Dose | Evid Based Complement Alternat Med. 2019 Nov 21;2019:3612587. doi: 10.1155/2019/3612587. eCollection 2019. | Motor Function | Mechanism |
| 31871478 | Synergistic Effects of the Combined Treatment of Acupuncture and KD5040 on Motor Function Tests in the MPTP-Induced PD Mouse Model | Evid Based Complement Alternat Med. 2019 Nov 21;2019:3612587. doi: 10.1155/2019/3612587. eCollection 2019. | Motor Function | Mechanism |
| 31871478 | We found that the combined treatment had a synergistic effect on motor function enhancement and a neuroprotective effect on dopaminergic neurons compared with the use of acupuncture or KD5040 alone. | Evid Based Complement Alternat Med. 2019 Nov 21;2019:3612587. doi: 10.1155/2019/3612587. eCollection 2019. | Neuroprotection Motor Function | Mechanism |
| 31871478 | We confirmed that Acu or KD5040 alone did not affect to the motor function of control mice ( in the Supplementary Materials). | Evid Based Complement Alternat Med. 2019 Nov 21;2019:3612587. doi: 10.1155/2019/3612587. eCollection 2019. | Motor Function | Mechanism |
| 31871478 | A previous study reported that acupuncture normalized abnormal motor function by increasing the availability of reduced dopamine. | Evid Based Complement Alternat Med. 2019 Nov 21;2019:3612587. doi: 10.1155/2019/3612587. eCollection 2019. | Motor Function | Mechanism |
| 31871478 | Therefore, the level of striatal dopamine may not necessarily be correlated with improvements in abnormal motor function. | Evid Based Complement Alternat Med. 2019 Nov 21;2019:3612587. doi: 10.1155/2019/3612587. eCollection 2019. | Motor Function | Mechanism |
| 31871478 | The combined treatment of acupuncture and low-dose KD5040 exhibited a synergistic effect on abnormal motor function and neuroprotection compared with treatment with acupuncture or KD5040 alone. | Evid Based Complement Alternat Med. 2019 Nov 21;2019:3612587. doi: 10.1155/2019/3612587. eCollection 2019. | Neuroprotection Motor Function | Mechanism |
| 31871478 | The motor function test revealed that significant recovery occurred on day 20 in the MPTP group with KD5040, compared with the MPTP group. | Evid Based Complement Alternat Med. 2019 Nov 21;2019:3612587. doi: 10.1155/2019/3612587. eCollection 2019. | Motor Function | Mechanism |
| 31871478 | Results of motor function tests in the four groups: (a) rotarod test, (b) cylinder test, and (c) pole test. | Evid Based Complement Alternat Med. 2019 Nov 21;2019:3612587. doi: 10.1155/2019/3612587. eCollection 2019. | Motor Function | Mechanism |
| 27852302 | The experimental endpoint was measured 3Â days after TBI as lateral fluid percussion causes motor dysfunction from 3Â days to 1Â year after TBI. | BMC Complement Altern Med. 2016 Nov 16;16(1):470. doi: 10.1186/s12906-016-1457-6. | Motor Function | Mechanism |
| 27852302 | Motor function evaluation | BMC Complement Altern Med. 2016 Nov 16;16(1):470. doi: 10.1186/s12906-016-1457-6. | Motor Function | Mechanism |
| 33193035 | Complex regional pain syndrome (CRPS) is a chronic neurological disorder with clinical characters of spontaneous pain, hyperalgesia, limb edema, vasomotor instability, and impairment of motor function. | Front Neurol. 2020 Oct 30;11:580997. doi: 10.3389/fneur.2020.580997. eCollection 2020. | Motor Function | Mechanism |
| 27073385 | Acupuncture at SJ5 specifically influences functional networks of the central nervous system, including sensorimotor areas, to improve sensorimotor function (Liu et al., 2009; Chen et al., 2014). | Neural Regen Res. 2016 Feb;11(2):305-11. doi: 10.4103/1673-5374.177740. | Motor Function | Mechanism |
| 26279808 | The motor functions of all pups were assessed via suspension test and modified BBB locomotor score. | J Korean Neurosurg Soc. 2015 Jul;58(1):14-21. doi: 10.3340/jkns.2015.58.1.14. Epub 2015 Jul 31. | Motor Function | Mechanism |
| 26279808 | Early intervention and rehabilitation training can improve the motor function in offspring with brain injury and reduce the expression of aquaporin-4 in damaged brain. | J Korean Neurosurg Soc. 2015 Jul;58(1):14-21. doi: 10.3340/jkns.2015.58.1.14. Epub 2015 Jul 31. | Motor Function | Mechanism |
| 26279808 | Motor function analysis | J Korean Neurosurg Soc. 2015 Jul;58(1):14-21. doi: 10.3340/jkns.2015.58.1.14. Epub 2015 Jul 31. | Motor Function | Mechanism |
| 26279808 | Motor function was assessed by using suspension test and modified BBB locomotor function testing on 14th days and 28th days old pups from each group. | J Korean Neurosurg Soc. 2015 Jul;58(1):14-21. doi: 10.3340/jkns.2015.58.1.14. Epub 2015 Jul 31. | Motor Function | Mechanism |
| 26279808 | Motor function analysis | J Korean Neurosurg Soc. 2015 Jul;58(1):14-21. doi: 10.3340/jkns.2015.58.1.14. Epub 2015 Jul 31. | Motor Function | Mechanism |
| 26279808 | Modified BBB locomotor function test score of 14 days-old pups of control group when compared with EI&R, acupuncture, consolidate and non treatment groups, the BBB test scores of EI&R, acupuncture, consolidate and non treatment groups were lower than control group, the difference was statistically significant (p<0.01); and the BBB test score of EI&R, acupuncture and consolidate groups were significantly higher than the non treatment group, the difference was statistically significant (p<0.01). | J Korean Neurosurg Soc. 2015 Jul;58(1):14-21. doi: 10.3340/jkns.2015.58.1.14. Epub 2015 Jul 31. | Motor Function | Mechanism |
| 26279808 | They also bring improvement in various abilities in brain damaged pups; such as irritability, learning ability, ability to balance and coordination as well as memory and motor function. | J Korean Neurosurg Soc. 2015 Jul;58(1):14-21. doi: 10.3340/jkns.2015.58.1.14. Epub 2015 Jul 31. | Motor Function | Mechanism |
| 26279808 | In this study it has been observed that the motor function of pups from control group was significantly better than the brain damaged pups. | J Korean Neurosurg Soc. 2015 Jul;58(1):14-21. doi: 10.3340/jkns.2015.58.1.14. Epub 2015 Jul 31. | Motor Function | Mechanism |
| 26279808 | After early intervention, acupuncture and rehabilitation training there was significant improvement in motor function in brain damaged pups, while in non treated pups there was no improvement. | J Korean Neurosurg Soc. 2015 Jul;58(1):14-21. doi: 10.3340/jkns.2015.58.1.14. Epub 2015 Jul 31. | Motor Function | Mechanism |
| 26279808 | Motor function test and suspension test scores were significantly higher in consolidate group (combined treatment with early intervention and rehabilitation and acupuncture) than individual early intervention & rehabilitation and acupuncture group. | J Korean Neurosurg Soc. 2015 Jul;58(1):14-21. doi: 10.3340/jkns.2015.58.1.14. Epub 2015 Jul 31. | Motor Function | Mechanism |
| 26279808 | But at subsequent days as pups grew day by day, motor function was improved. | J Korean Neurosurg Soc. 2015 Jul;58(1):14-21. doi: 10.3340/jkns.2015.58.1.14. Epub 2015 Jul 31. | Motor Function | Mechanism |
| 26279808 | It is due to the combined effects of multiple mechanisms of biochemical chain reaction.The hippocampus and cortex regions of the brain are important and closely associated with learning, memory and sensory-motor functions. | J Korean Neurosurg Soc. 2015 Jul;58(1):14-21. doi: 10.3340/jkns.2015.58.1.14. Epub 2015 Jul 31. | Learning and Memory Ability Motor Function | Mechanism |
| 26279808 | The damage to hippocampus and cerebral cortex result in impairment of learning, memory and sensori-motor functions. | J Korean Neurosurg Soc. 2015 Jul;58(1):14-21. doi: 10.3340/jkns.2015.58.1.14. Epub 2015 Jul 31. | Learning and Memory Ability Motor Function | Mechanism |
| 26279808 | The results of this study shows that brain damage can lead to long-term impairment of learning, memory and sensorimotor function. | J Korean Neurosurg Soc. 2015 Jul;58(1):14-21. doi: 10.3340/jkns.2015.58.1.14. Epub 2015 Jul 31. | Learning and Memory Ability Motor Function | Mechanism |
| 26279808 | The experimental results show that early intervention and rehabilitation in brain injured pups can significantly improve motor function, enhance the expression of AQP4 suggesting that AQP4 may be important in brain damage recovery processes. | J Korean Neurosurg Soc. 2015 Jul;58(1):14-21. doi: 10.3340/jkns.2015.58.1.14. Epub 2015 Jul 31. | Motor Function | Mechanism |
| 34804173 | Changes in standing ability, sensorimotor function, and postural swing are the main poststroke complications and are closely related to the increased risk of falls and balance disorders. | Evid Based Complement Alternat Med. 2021 Nov 12;2021:1418616. doi: 10.1155/2021/1418616. eCollection 2021. | Motor Function | Mechanism |
| 34804173 | In the present study, our results demonstrated that the combination therapy of SA and TT successfully improves the short-term and long-term motor function in pMCAO rats, which is better than using SA or TT alone. | Evid Based Complement Alternat Med. 2021 Nov 12;2021:1418616. doi: 10.1155/2021/1418616. eCollection 2021. | Motor Function | Mechanism |
| 34804173 | Therefore, the decrease of neuronal apoptosis mediated by the inactivation of the caspase-8/-9/-3 pathway is an important way for ST-T in the motor function improvement in ischemic stroke (Figure 9). | Evid Based Complement Alternat Med. 2021 Nov 12;2021:1418616. doi: 10.1155/2021/1418616. eCollection 2021. | Motor Function | Mechanism |
| 34804173 | Moreover, we found that the combined therapy involving scalp acupuncture and treadmill training improves the motor function by upregulating the expression level of cIAP1, and its short-term and long-term effects are better than scalp acupuncture and treadmill training alone. | Evid Based Complement Alternat Med. 2021 Nov 12;2021:1418616. doi: 10.1155/2021/1418616. eCollection 2021. | Motor Function | Mechanism |
| 36277498 | To determine whether the locomotor function was altered in mice following EA treatment, the rotarod test was performed. | Front Mol Neurosci. 2022 Oct 6;15:979483. doi: 10.3389/fnmol.2022.979483. eCollection 2022. | Motor Function | Mechanism |
| 36277498 | To assess whether EA treatment impaired the locomotor function of mice, rotarod tests were performed at 0.5 h after EA, which was the time point that related to the maximal attenuation of orofacial hyperalgesia in EA-treated pT-ION mice. | Front Mol Neurosci. 2022 Oct 6;15:979483. doi: 10.3389/fnmol.2022.979483. eCollection 2022. | Motor Function | Mechanism |
| 36277498 | These findings demonstrated that EA has long-term analgesic effects on pT-ION model mice without disrupting their motor function. | Front Mol Neurosci. 2022 Oct 6;15:979483. doi: 10.3389/fnmol.2022.979483. eCollection 2022. | Analgesic Effect Motor Function | Mechanism |
| 36277498 | On day 21 after pT-ION surgery (day 14 after EA every 2 days), no effect of EA on motor function is shown as the constant total distance (A) in the open-field test (OFT). | Front Mol Neurosci. 2022 Oct 6;15:979483. doi: 10.3389/fnmol.2022.979483. eCollection 2022. | Motor Function | Mechanism |
| 35046719 | Consequently, we used an MIA-induced KOA model to observe the therapeutic effects of MA on pain, inflammation and motor function in KOA model rats. | J Pain Res. 2022 Jan 11;15:93-103. doi: 10.2147/JPR.S346242. eCollection 2022. | Motor Function | Mechanism |
| 27880769 | The motor function of the left hind limb was assessed before the crush injury and 4 weeks post injury using the toe-spreading reflex. | PLoS One. 2016 Nov 23;11(11):e0164652. doi: 10.1371/journal.pone.0164652. eCollection 2016. | Motor Function | Mechanism |
| 27880769 | Motor function recovery was assessed by TSI at 4 weeks of treatment. | PLoS One. 2016 Nov 23;11(11):e0164652. doi: 10.1371/journal.pone.0164652. eCollection 2016. | Motor Function | Mechanism |
| 27880769 | Alternatively, FA value can be used to directly determine the prognosis of motor function after peripheral nerve injury. | PLoS One. 2016 Nov 23;11(11):e0164652. doi: 10.1371/journal.pone.0164652. eCollection 2016. | Motor Function | Mechanism |
| 23573131 | Acupuncture and electroacupuncture cause physiobiological effects that promote movement and function after peripheral nerve injury in individuals. | Evid Based Complement Alternat Med. 2013;2013:514610. doi: 10.1155/2013/514610. Epub 2013 Mar 12. | Motor Function | Mechanism |
| 23573131 | It is believed that acupuncture and electroacupuncture would do well to ameliorate nerve regeneration and movement function recovery. | Evid Based Complement Alternat Med. 2013;2013:514610. doi: 10.1155/2013/514610. Epub 2013 Mar 12. | Motor Function | Mechanism |
| 23573131 | Although it is uncertain whether electrical stimulation promotes an outgrowth of neural components in developing nerves, the movement function-improving capability of electrical stimulation on regenerated nerves is obvious. | Evid Based Complement Alternat Med. 2013;2013:514610. doi: 10.1155/2013/514610. Epub 2013 Mar 12. | Motor Function | Mechanism |
| 23573131 | The kinematic grasp analysis to median nerve function evaluation is usually designed to assess individual upper motor functions, which can prevent the interference of compensatory movements from healthy limbs. | Evid Based Complement Alternat Med. 2013;2013:514610. doi: 10.1155/2013/514610. Epub 2013 Mar 12. | Motor Function | Mechanism |
| 30028333 | Compared with decompression alone, hind limb motor function recovery was superior after decompression for 12 and 48 hours combined with electroacupuncture. | Neural Regen Res. 2018 Jul;13(7):1241-1246. doi: 10.4103/1673-5374.235062. | Motor Function | Mechanism |
| 30028333 | However, the recovery of motor function was not significantly different at 14 days after treatment in rats receiving decompression for 12 hours. | Neural Regen Res. 2018 Jul;13(7):1241-1246. doi: 10.4103/1673-5374.235062. | Motor Function | Mechanism |
| 30028333 | Hind limb locomotor function score | Neural Regen Res. 2018 Jul;13(7):1241-1246. doi: 10.4103/1673-5374.235062. | Motor Function | Mechanism |
| 30028333 | Evaluation of motor ability was graded using a 0-21 point scoring system called the Basso, Beattie, and Bresnahan locomotor scale (BBB) (Bhimani et al., 2017), which assesses a combination of rat hind limb movements, trunk position, stability, stepping, coordination, paw placement, toe clearance, and tail position. | Neural Regen Res. 2018 Jul;13(7):1241-1246. doi: 10.4103/1673-5374.235062. | Motor Function | Mechanism |
| 30028333 | Effects of decompression combined with EA on hind limb locomotor function in rats with acute upper cervical SCI | Neural Regen Res. 2018 Jul;13(7):1241-1246. doi: 10.4103/1673-5374.235062. | Motor Function | Mechanism |
| 30028333 | Therefore, for decompression at 12 hours, EA and MP treatment can promote the recovery of motor function, but may not make a difference in final functional recovery. | Neural Regen Res. 2018 Jul;13(7):1241-1246. doi: 10.4103/1673-5374.235062. | Motor Function | Mechanism |
| 30028333 | For decompression at 48 hours, EA and MP treatment can promote the recovery of motor function and improve the final functional recovery. | Neural Regen Res. 2018 Jul;13(7):1241-1246. doi: 10.4103/1673-5374.235062. | Motor Function | Mechanism |
| 30028333 | Early decompression combined with EA promoted the recovery of motor function more effectively than decompression alone. | Neural Regen Res. 2018 Jul;13(7):1241-1246. doi: 10.4103/1673-5374.235062. | Motor Function | Mechanism |
| 31889778 | The physiological function and movement of the GI are affected by the neurotransmitter and immunological signalling produced by the central nervous system as well as by the intestine. | Saudi J Biol Sci. 2019 Dec;26(8):1948-1955. doi: 10.1016/j.sjbs.2019.07.003. Epub 2019 Jul 13. | Immunity Motor Function | Mechanism |
| 35321503 | The motor function of rats was evaluated by Modified Neurological Severity Score (mNSS). | Evid Based Complement Alternat Med. 2022 Mar 14;2022:1649605. doi: 10.1155/2022/1649605. eCollection 2022. | Motor Function | Mechanism |
| 35321503 | The fast recovery motor function was consistent with the protective action of scalp electroacupuncture on the nerve cells in the rats after CIRI. | Evid Based Complement Alternat Med. 2022 Mar 14;2022:1649605. doi: 10.1155/2022/1649605. eCollection 2022. | Motor Function | Mechanism |
| 35321503 | Our result showed that improved brain function could be attained on day 7 (acute phase), using an assay of motor functions (mNSS), and the improvement of motor function seemed sustainable with time through mNSS on days 14 and 21 (Figure 1). | Evid Based Complement Alternat Med. 2022 Mar 14;2022:1649605. doi: 10.1155/2022/1649605. eCollection 2022. | Motor Function | Mechanism |
| 35321503 | The fast recovery motor function was consistent with the cerebral histomorphological manifestations of H&E staining, including the decrease of nucleus dissolution and the increases in the number of nerve and capillary cells in the rats of electroacupuncture group (Figure 3). | Evid Based Complement Alternat Med. 2022 Mar 14;2022:1649605. doi: 10.1155/2022/1649605. eCollection 2022. | Motor Function | Mechanism |