Detail information
ID ENOM00035
Accession GSE24830
Status Public on Oct 23, 2010
Title Gene expression data from cervical spinal cord regions of MPTP-intoxicated mouse by acupuncture
Organism Mus musculus
Experiment type Expression profiling by array
Summary
It has been shown that acupuncture at acupoints GB34 and LR3 inhibits the degeneration of nigrostriatal neurons in an 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson’s disease. This preventative effect of peripheral acupuncture stimulation is hypothesized to be transmitted through the spinal cord to the nigrostriatal neurons. The gene expression profile changes following acupuncture at the acupoints were investigated in the cervical spinal cord of an MPTP-induced parkinsonism model using an Affymetrix genechip mouse gene 1.0 ST array.
Samples
GSM ID Sample info Characteristics Description
GSM611089 Control mouse 1 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: Control Gene expression data from normal cervical spinal cord regions
GSM611090 Control mouse 2 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: Control Gene expression data from normal cervical spinal cord regions
GSM611091 MPTP-treated mouse 1 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP-treated Gene expression data from cervical spinal cord regions of MPTP-intoxicated mouse
GSM611092 MPTP-treated mouse 2 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP-treated Gene expression data from cervical spinal cord regions of MPTP-intoxicated mouse
GSM611093 MPTP and acupoints acupuncture-treated mouse 1 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP and acupoints acupuncture-treated Gene expression data from cervical spinal cord regions following acupoints-acupuncture-treatment to MPTP-intoxicated mouse
GSM611094 MPTP and acupoints acupuncture-treated mouse 2 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP and acupoints acupuncture-treated Gene expression data from cervical spinal cord regions following acupoints-acupuncture-treatment to MPTP-intoxicated mouse
GSM611095 MPTP and nonacupoints acupuncture-treated mouse 1 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP and nonacupoints acupuncture-treated Gene expression data from cervical spinal cord regions following nonacupoints-acupuncture-treatment to MPTP-intoxicated mouse
GSM611096 MPTP and nonacupoints acupuncture-treated mouse 2 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP and nonacupoints acupuncture-treated Gene expression data from cervical spinal cord regions following nonacupoints-acupuncture-treatment to MPTP-intoxicated mouse
Platform GPL6246: [MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]
Indicator
Ctla2a, EG383229, Ppbp, Ube2l6, EG665033, ENSMUSG00000055323, Obox6, Pbp2, Tmem150, 1810030J14Rik Ctla2a, EG383229 (Gm5226), A530032D15 Rik, Alas2, Arhgap11a, Ccl3, Cenpq, Hba-a1, Hba-a2, Hbb-b1, Ly96
EG665033 (Gm7455), ENSMUSG00000055323 (Gm9967), Fut11, Atp2a1, Dub2a, Klhl31, Myh4, Tnnt3, Trdn
Download Download data in GEO database