| GSM ID |
Sample info |
Characteristics |
Description |
| GSM8083291 |
patient C1P1, before first course of MP, T cells |
tissue: peripheral blood
patient id: C1P1
mp course: first
time point: before
cell population: CD4+ T cells
clinical evaluation: non-responder
percentage in pbmc: 34.9
cells per ml: 2982000
purity (%): 98.1
rna integrity number: 7.8
age (years): 60
Sex: female
body weight (in kg): 75.4
body size (in cm): 168
body mass index: 26.7
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 11
number of relapses in the past 2 years: 0
duration since last relapse (months): 133
edss score: 3.5
disease-modifying therapy: teriflunomide
number of other medications taken: 5
neurological dysfunction: recurring
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: yes
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 5000
days from first to last mp application: 4
side effects to mp: hair loss |
Gene expression data for a patient with MS treated with methylprednisolone
C1P1-M1-T0-CD4 |
| GSM8083292 |
patient C1P1, after first course of MP, T cells |
tissue: peripheral blood
patient id: C1P1
mp course: first
time point: after
cell population: CD4+ T cells
clinical evaluation: non-responder
percentage in pbmc: 25.9
cells per ml: 304500
purity (%): 95.3
rna integrity number: 8.7
age (years): 60
Sex: female
body weight (in kg): 75.4
body size (in cm): 168
body mass index: 26.7
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 11
number of relapses in the past 2 years: 0
duration since last relapse (months): 133
edss score: NA
disease-modifying therapy: teriflunomide
number of other medications taken: 5
neurological dysfunction: recurring
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: worse
fs: sensory: better
fs: visual: unchanged
total dose of mp in mg: 5000
days from first to last mp application: 4
side effects to mp: hair loss |
Gene expression data for a patient with MS treated with methylprednisolone
C1P1-M1-T1-CD4 |
| GSM8083293 |
patient C1P1, before second course of MP, T cells |
tissue: peripheral blood
patient id: C1P1
mp course: second
time point: before
cell population: CD4+ T cells
clinical evaluation: responder
percentage in pbmc: 27.8
cells per ml: 1254750
purity (%): 96.7
rna integrity number: 8.3
age (years): 60
Sex: female
body weight (in kg): 75.4
body size (in cm): 168
body mass index: 26.7
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 11
number of relapses in the past 2 years: 0
duration since last relapse (months): 134
edss score: 3.5
disease-modifying therapy: teriflunomide
number of other medications taken: 5
neurological dysfunction: recurring
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: yes
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 6000
days from first to last mp application: 2
side effects to mp: headache, diarrhea |
Gene expression data for a patient with MS treated with methylprednisolone
C1P1-M2-T0-CD4 |
| GSM8083294 |
patient C1P1, after second course of MP, T cells |
tissue: peripheral blood
patient id: C1P1
mp course: second
time point: after
cell population: CD4+ T cells
clinical evaluation: responder
percentage in pbmc: 6.6
cells per ml: 231000
purity (%): 93.7
rna integrity number: 9.4
age (years): 60
Sex: female
body weight (in kg): 75.4
body size (in cm): 168
body mass index: 26.7
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 11
number of relapses in the past 2 years: 0
duration since last relapse (months): 134
edss score: NA
disease-modifying therapy: teriflunomide
number of other medications taken: 5
neurological dysfunction: recurring
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: worse
fs: sensory: better
fs: visual: unchanged
total dose of mp in mg: 6000
days from first to last mp application: 2
side effects to mp: headache, diarrhea |
Gene expression data for a patient with MS treated with methylprednisolone
C1P1-M2-T1-CD4 |
| GSM8083295 |
patient C1P2, before first course of MP, B cells |
tissue: peripheral blood
patient id: C1P2
mp course: first
time point: before
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 4.7
cells per ml: 236250
purity (%): 91.9
rna integrity number: 9.0
age (years): 38
Sex: male
body weight (in kg): 67
body size (in cm): 183
body mass index: 20.0
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 17
number of relapses in the past 2 years: 0
duration since last relapse (months): 206
edss score: 3.0
disease-modifying therapy: teriflunomide
number of other medications taken: 0
neurological dysfunction: recurring
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: yes
fs: cerebral: no
fs: pyramidal: yes
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 5000
days from first to last mp application: 6
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C1P2-M1-T0-CD19 |
| GSM8083296 |
patient C1P2, after first course of MP, B cells |
tissue: peripheral blood
patient id: C1P2
mp course: first
time point: after
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 3.7
cells per ml: 283500
purity (%): 91.0
rna integrity number: 9.1
age (years): 38
Sex: male
body weight (in kg): 67
body size (in cm): 183
body mass index: 20.0
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 17
number of relapses in the past 2 years: 0
duration since last relapse (months): 206
edss score: 3.0
disease-modifying therapy: teriflunomide
number of other medications taken: 0
neurological dysfunction: recurring
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: better
fs: cerebral: unchanged
fs: pyramidal: better
fs: sensory: better
fs: visual: unchanged
total dose of mp in mg: 5000
days from first to last mp application: 6
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C1P2-M1-T1-CD19 |
| GSM8083297 |
patient C1P2, before first course of MP, T cells |
tissue: peripheral blood
patient id: C1P2
mp course: first
time point: before
cell population: CD4+ T cells
clinical evaluation: responder
percentage in pbmc: 28.7
cells per ml: 693000
purity (%): 96.0
rna integrity number: 8.3
age (years): 38
Sex: male
body weight (in kg): 67
body size (in cm): 183
body mass index: 20.0
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 17
number of relapses in the past 2 years: 0
duration since last relapse (months): 206
edss score: 3.0
disease-modifying therapy: teriflunomide
number of other medications taken: 0
neurological dysfunction: recurring
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: yes
fs: cerebral: no
fs: pyramidal: yes
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 5000
days from first to last mp application: 6
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C1P2-M1-T0-CD4 |
| GSM8083298 |
patient C1P2, after first course of MP, T cells |
tissue: peripheral blood
patient id: C1P2
mp course: first
time point: after
cell population: CD4+ T cells
clinical evaluation: responder
percentage in pbmc: 11.5
cells per ml: 624750
purity (%): 96.0
rna integrity number: 8.3
age (years): 38
Sex: male
body weight (in kg): 67
body size (in cm): 183
body mass index: 20.0
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 17
number of relapses in the past 2 years: 0
duration since last relapse (months): 206
edss score: 3.0
disease-modifying therapy: teriflunomide
number of other medications taken: 0
neurological dysfunction: recurring
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: better
fs: cerebral: unchanged
fs: pyramidal: better
fs: sensory: better
fs: visual: unchanged
total dose of mp in mg: 5000
days from first to last mp application: 6
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C1P2-M1-T1-CD4 |
| GSM8083299 |
patient C1P3, before first course of MP, B cells |
tissue: peripheral blood
patient id: C1P3
mp course: first
time point: before
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 10.0
cells per ml: 498750
purity (%): 98.8
rna integrity number: 8.9
age (years): 34
Sex: female
body weight (in kg): 63
body size (in cm): 168
body mass index: 22.3
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 8
number of relapses in the past 2 years: 1
duration since last relapse (months): 5
edss score: 2.5
disease-modifying therapy: peginterferon beta-1a
number of other medications taken: 1
neurological dysfunction: recurring
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: no
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 5000
days from first to last mp application: 4
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C1P3-M1-T0-CD19 |
| GSM8083300 |
patient C1P3, after first course of MP, B cells |
tissue: peripheral blood
patient id: C1P3
mp course: first
time point: after
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 6.7
cells per ml: 383250
purity (%): 97.9
rna integrity number: 9.4
age (years): 34
Sex: female
body weight (in kg): 63
body size (in cm): 168
body mass index: 22.3
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 8
number of relapses in the past 2 years: 1
duration since last relapse (months): 5
edss score: 2.5
disease-modifying therapy: peginterferon beta-1a
number of other medications taken: 1
neurological dysfunction: recurring
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: unchanged
fs: sensory: better
fs: visual: unchanged
total dose of mp in mg: 5000
days from first to last mp application: 4
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C1P3-M1-T1-CD19 |
| GSM8083301 |
patient C1P3, before first course of MP, T cells |
tissue: peripheral blood
patient id: C1P3
mp course: first
time point: before
cell population: CD4+ T cells
clinical evaluation: responder
percentage in pbmc: 31.0
cells per ml: 1134000
purity (%): 94.7
rna integrity number: 8.1
age (years): 34
Sex: female
body weight (in kg): 63
body size (in cm): 168
body mass index: 22.3
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 8
number of relapses in the past 2 years: 1
duration since last relapse (months): 5
edss score: 2.5
disease-modifying therapy: peginterferon beta-1a
number of other medications taken: 1
neurological dysfunction: recurring
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: no
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 5000
days from first to last mp application: 4
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C1P3-M1-T0-CD4 |
| GSM8083302 |
patient C1P3, after first course of MP, T cells |
tissue: peripheral blood
patient id: C1P3
mp course: first
time point: after
cell population: CD4+ T cells
clinical evaluation: responder
percentage in pbmc: 18.1
cells per ml: 640500
purity (%): 96.2
rna integrity number: 8.1
age (years): 34
Sex: female
body weight (in kg): 63
body size (in cm): 168
body mass index: 22.3
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 8
number of relapses in the past 2 years: 1
duration since last relapse (months): 5
edss score: 2.5
disease-modifying therapy: peginterferon beta-1a
number of other medications taken: 1
neurological dysfunction: recurring
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: unchanged
fs: sensory: better
fs: visual: unchanged
total dose of mp in mg: 5000
days from first to last mp application: 4
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C1P3-M1-T1-CD4 |
| GSM8083303 |
patient C1P3, before second course of MP, T cells |
tissue: peripheral blood
patient id: C1P3
mp course: second
time point: before
cell population: CD4+ T cells
clinical evaluation: responder
percentage in pbmc: 30.3
cells per ml: 897750
purity (%): 97.0
rna integrity number: 8.5
age (years): 34
Sex: female
body weight (in kg): 63
body size (in cm): 168
body mass index: 22.3
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 8
number of relapses in the past 2 years: 1
duration since last relapse (months): 5
edss score: 2.5
disease-modifying therapy: peginterferon beta-1a
number of other medications taken: 1
neurological dysfunction: recurring
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: no
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 6000
days from first to last mp |
Gene expression data for a patient with MS treated with methylprednisolone
C1P3-M2-T0-CD4 |
| GSM8083304 |
patient C1P3, after second course of MP, T cells |
tissue: peripheral blood
patient id: C1P3
mp course: second
time point: after
cell population: CD4+ T cells
clinical evaluation: responder
percentage in pbmc: 27.7
cells per ml: 1433250
purity (%): 97.5
rna integrity number: 8.3
age (years): 34
Sex: female
body weight (in kg): 63
body size (in cm): 168
body mass index: 22.3
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 8
number of relapses in the past 2 years: 1
duration since last relapse (months): 5
edss score: 2.5
disease-modifying therapy: peginterferon beta-1a
number of other medications taken: 1
neurological dysfunction: recurring
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: unchanged
fs: sensory: better
fs: visual: unchanged
total dose of mp in mg: 6000
days from first to last mp application: 5
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C1P3-M2-T1-CD4 |
| GSM8083305 |
patient C1P4, before first course of MP, B cells |
tissue: peripheral blood
patient id: C1P4
mp course: first
time point: before
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 7.3
cells per ml: 378000
purity (%): 96.3
rna integrity number: 9.6
age (years): 53
Sex: female
body weight (in kg): 58
body size (in cm): 159
body mass index: 22.9
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 3
number of relapses in the past 2 years: 0
duration since last relapse (months): 34
edss score: 3.0
disease-modifying therapy: glatiramer acetate
number of other medications taken: 5
neurological dysfunction: recurring
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: yes
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 5000
days from first to last mp application: 4
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C1P4-M1-T0-CD19 |
| GSM8083306 |
patient C1P4, after first course of MP, B cells |
tissue: peripheral blood
patient id: C1P4
mp course: first
time point: after
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 7.5
cells per ml: 939750
purity (%): 96.7
rna integrity number: 8.8
age (years): 53
Sex: female
body weight (in kg): 58
body size (in cm): 159
body mass index: 22.9
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 3
number of relapses in the past 2 years: 0
duration since last relapse (months): 34
edss score: NA
disease-modifying therapy: glatiramer acetate
number of other medications taken: 5
neurological dysfunction: recurring
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: better
fs: sensory: better
fs: visual: unchanged
total dose of mp in mg: 5000
days from first to last mp application: 4
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C1P4-M1-T1-CD19 |
| GSM8083307 |
patient C1P4, before first course of MP, T cells |
tissue: peripheral blood
patient id: C1P4
mp course: first
time point: before
cell population: CD4+ T cells
clinical evaluation: responder
percentage in pbmc: 38.1
cells per ml: 1522500
purity (%): 98.7
rna integrity number: NA
age (years): 53
Sex: female
body weight (in kg): 58
body size (in cm): 159
body mass index: 22.9
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 3
number of relapses in the past 2 years: 0
duration since last relapse (months): 34
edss score: 3.0
disease-modifying therapy: glatiramer acetate
number of other medications taken: 5
neurological dysfunction: recurring
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: yes
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 5000
days from first to last mp application: 4
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C1P4-M1-T0-CD4 |
| GSM8083308 |
patient C1P4, after first course of MP, T cells |
tissue: peripheral blood
patient id: C1P4
mp course: first
time point: after
cell population: CD4+ T cells
clinical evaluation: responder
percentage in pbmc: 15.9
cells per ml: 1617000
purity (%): 98.3
rna integrity number: 8.5
age (years): 53
Sex: female
body weight (in kg): 58
body size (in cm): 159
body mass index: 22.9
current smoker: no
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 3
number of relapses in the past 2 years: 0
duration since last relapse (months): 34
edss score: NA
disease-modifying therapy: glatiramer acetate
number of other medications taken: 5
neurological dysfunction: recurring
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: better
fs: sensory: better
fs: visual: unchanged
total dose of mp in mg: 5000
days from first to last mp application: 4
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C1P4-M1-T1-CD4 |
| GSM8083309 |
patient C1P5, before first course of MP, T cells |
tissue: peripheral blood
patient id: C1P5
mp course: first
time point: before
cell population: CD4+ T cells
clinical evaluation: non-responder
percentage in pbmc: 31.6
cells per ml: 1344000
purity (%): 99.1
rna integrity number: 8.0
age (years): 42
Sex: male
body weight (in kg): 57
body size (in cm): 180
body mass index: 17.6
current smoker: yes
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 16
number of relapses in the past 2 years: 2
duration since last relapse (months): NA
edss score: 7.5
disease-modifying therapy: ocrelizumab
number of other medications taken: 6
neurological dysfunction: new
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: yes
fs: sensory: no
fs: visual: no
total dose of mp in mg: 5000
days from first to last mp application: 5
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C1P5-M1-T0-CD4 |
| GSM8083310 |
patient C1P5, after first course of MP, T cells |
tissue: peripheral blood
patient id: C1P5
mp course: first
time point: after
cell population: CD4+ T cells
clinical evaluation: non-responder
percentage in pbmc: 21.9
cells per ml: 1165500
purity (%): 98.9
rna integrity number: 8.4
age (years): 42
Sex: male
body weight (in kg): 57
body size (in cm): 180
body mass index: 17.6
current smoker: yes
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 16
number of relapses in the past 2 years: 2
duration since last relapse (months): NA
edss score: 7.5
disease-modifying therapy: ocrelizumab
number of other medications taken: 6
neurological dysfunction: new
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: unchanged
fs: sensory: unchanged
fs: visual: unchanged
total dose of mp in mg: 5000
days from first to last mp application: 5
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C1P5-M1-T1-CD4 |
| GSM8083311 |
patient C1P5, before second course of MP, T cells |
tissue: peripheral blood
patient id: C1P5
mp course: second
time point: before
cell population: CD4+ T cells
clinical evaluation: responder
percentage in pbmc: 26.9
cells per ml: 1233750
purity (%): 97.8
rna integrity number: 8.5
age (years): 42
Sex: male
body weight (in kg): 57
body size (in cm): 180
body mass index: 17.6
current smoker: yes
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 16
number of relapses in the past 2 years: 2
duration since last relapse (months): NA
edss score: 7.5
disease-modifying therapy: ocrelizumab
number of other medications taken: 6
neurological dysfunction: new
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: yes
fs: sensory: no
fs: visual: no
total dose of mp in mg: 4000
days from first to last mp application: 2
side effects to mp: cardiovascular problems |
Gene expression data for a patient with MS treated with methylprednisolone
C1P5-M2-T0-CD4 |
| GSM8083312 |
patient C1P5, after second course of MP, T cells |
tissue: peripheral blood
patient id: C1P5
mp course: second
time point: after
cell population: CD4+ T cells
clinical evaluation: responder
percentage in pbmc: 11.0
cells per ml: 514500
purity (%): 98.6
rna integrity number: 8.7
age (years): 42
Sex: male
body weight (in kg): 57
body size (in cm): 180
body mass index: 17.6
current smoker: yes
study center: Berlin
course of disease: CIS/RRMS
disease duration (years): 16
number of relapses in the past 2 years: 2
duration since last relapse (months): NA
edss score: 7.5
disease-modifying therapy: ocrelizumab
number of other medications taken: 6
neurological dysfunction: new
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: better
fs: sensory: unchanged
fs: visual: unchanged
total dose of mp in mg: 4000
days from first to last mp application: 2
side effects to mp: cardiovascular problems |
Gene expression data for a patient with MS treated with methylprednisolone
C1P5-M2-T1-CD4 |
| GSM8083313 |
patient C2P1, before first course of MP, B cells |
tissue: peripheral blood
patient id: C2P1
mp course: first
time point: before
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 11.7
cells per ml: 2604000
purity (%): 96.7
rna integrity number: 8.5
age (years): 24
Sex: female
body weight (in kg): 60
body size (in cm): 170
body mass index: 20.8
current smoker: yes
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 0
number of relapses in the past 2 years: 1
duration since last relapse (months): 6
edss score: 3.0
disease-modifying therapy: none
number of other medications taken: 0
neurological dysfunction: new
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: no
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 3000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P1-M1-T0-CD19 |
| GSM8083314 |
patient C2P1, after first course of MP, B cells |
tissue: peripheral blood
patient id: C2P1
mp course: first
time point: after
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 8.8
cells per ml: 630000
purity (%): 97.4
rna integrity number: 8.4
age (years): 24
Sex: female
body weight (in kg): 60
body size (in cm): 170
body mass index: 20.8
current smoker: yes
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 0
number of relapses in the past 2 years: 1
duration since last relapse (months): 6
edss score: NA
disease-modifying therapy: none
number of other medications taken: 0
neurological dysfunction: new
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: unchanged
fs: sensory: better
fs: visual: unchanged
total dose of mp in mg: 3000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P1-M1-T1-CD19 |
| GSM8083315 |
patient C2P1, before first course of MP, T cells |
tissue: peripheral blood
patient id: C2P1
mp course: first
time point: before
cell population: CD4+ T cells
clinical evaluation: responder
percentage in pbmc: 41.5
cells per ml: 2436000
purity (%): 94.6
rna integrity number: 8.0
age (years): 24
Sex: female
body weight (in kg): 60
body size (in cm): 170
body mass index: 20.8
current smoker: yes
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 0
number of relapses in the past 2 years: 1
duration since last relapse (months): 6
edss score: 3.0
disease-modifying therapy: none
number of other medications taken: 0
neurological dysfunction: new
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: no
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 3000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P1-M1-T0-CD4 |
| GSM8083316 |
patient C2P1, after first course of MP, T cells |
tissue: peripheral blood
patient id: C2P1
mp course: first
time point: after
cell population: CD4+ T cells
clinical evaluation: responder
percentage in pbmc: 6.2
cells per ml: 346500
purity (%): 86.5
rna integrity number: 8.0
age (years): 24
Sex: female
body weight (in kg): 60
body size (in cm): 170
body mass index: 20.8
current smoker: yes
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 0
number of relapses in the past 2 years: 1
duration since last relapse (months): 6
edss score: NA
disease-modifying therapy: none
number of other medications taken: 0
neurological dysfunction: new
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: unchanged
fs: sensory: better
fs: visual: unchanged
total dose of mp in mg: 3000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P1-M1-T1-CD4 |
| GSM8083317 |
patient C2P2, before first course of MP, B cells |
tissue: peripheral blood
patient id: C2P2
mp course: first
time point: before
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 0.9
cells per ml: 467250
purity (%): 87.3
rna integrity number: 8.8
age (years): 41
Sex: female
body weight (in kg): 71
body size (in cm): 170
body mass index: 24.6
current smoker: no
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 0
number of relapses in the past 2 years: 3
duration since last relapse (months): 3
edss score: NA
disease-modifying therapy: glatiramer acetate
number of other medications taken: 1
neurological dysfunction: new
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: yes
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 3000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P2-M1-T0-CD19 |
| GSM8083318 |
patient C2P2, after first course of MP, B cells |
tissue: peripheral blood
patient id: C2P2
mp course: first
time point: after
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 6.3
cells per ml: 199500
purity (%): 97.6
rna integrity number: 9.5
age (years): 41
Sex: female
body weight (in kg): 71
body size (in cm): 170
body mass index: 24.6
current smoker: no
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 0
number of relapses in the past 2 years: 3
duration since last relapse (months): 3
edss score: 1.5
disease-modifying therapy: glatiramer acetate
number of other medications taken: 1
neurological dysfunction: new
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: better
fs: sensory: unchanged
fs: visual: unchanged
total dose of mp in mg: 3000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P2-M1-T1-CD19 |
| GSM8083319 |
patient C2P3, before first course of MP, B cells |
tissue: peripheral blood
patient id: C2P3
mp course: first
time point: before
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 12.2
cells per ml: 1170750
purity (%): 97.2
rna integrity number: 8.5
age (years): 20
Sex: female
body weight (in kg): 55
body size (in cm): 165
body mass index: 20.2
current smoker: yes
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 6
number of relapses in the past 2 years: 0
duration since last relapse (months): NA
edss score: 1.5
disease-modifying therapy: natalizumab
number of other medications taken: 1
neurological dysfunction: new
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: no
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 3000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P3-M1-T0-CD19 |
| GSM8083320 |
patient C2P3, after first course of MP, B cells |
tissue: peripheral blood
patient id: C2P3
mp course: first
time point: before
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 12.2
cells per ml: 1170750
purity (%): 97.2
rna integrity number: 8.5
age (years): 20
Sex: female
body weight (in kg): 55
body size (in cm): 165
body mass index: 20.2
current smoker: yes
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 6
number of relapses in the past 2 years: 0
duration since last relapse (months): NA
edss score: 1.5
disease-modifying therapy: natalizumab
number of other medications taken: 1
neurological dysfunction: new
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: no
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 3000
days from first to last mp application: 2
side effects to mp: none |
|
| GSM8083321 |
patient C2P3, before first course of MP, T cells |
tissue: peripheral blood
patient id: C2P3
mp course: first
time point: after
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 20.2
cells per ml: 1711500
purity (%): 94.3
rna integrity number: 7.3
age (years): 20
Sex: female
body weight (in kg): 55
body size (in cm): 165
body mass index: 20.2
current smoker: yes
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 6
number of relapses in the past 2 years: 0
duration since last relapse (months): NA
edss score: 1.5
disease-modifying therapy: natalizumab
number of other medications taken: 1
neurological dysfunction: new
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: unchanged
fs: sensory: better
fs: visual: unchanged
total dose of mp in mg: 3000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P3-M1-T1-CD19 |
| GSM8083322 |
patient C2P3, after first course of MP, T cells |
tissue: peripheral blood
patient id: C2P3
mp course: first
time point: before
cell population: CD4+ T cells
clinical evaluation: responder
percentage in pbmc: 22.8
cells per ml: 992250
purity (%): 96.5
rna integrity number: 8.2
age (years): 20
Sex: female
body weight (in kg): 55
body size (in cm): 165
body mass index: 20.2
current smoker: yes
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 6
number of relapses in the past 2 years: 0
duration since last relapse (months): NA
edss score: 1.5
disease-modifying therapy: natalizumab
number of other medications taken: 1
neurological dysfunction: new
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: no
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 3000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P3-M1-T0-CD4 |
| GSM8083323 |
patient C2P4, before first course of MP, B cells |
tissue: peripheral blood
patient id: C2P4
mp course: first
time point: before
cell population: CD19+ B cells
clinical evaluation: non-responder
percentage in pbmc: 8.0
cells per ml: 1690500
purity (%): 96.3
rna integrity number: 9.0
age (years): 60
Sex: male
body weight (in kg): 97
body size (in cm): 170
body mass index: 33.6
current smoker: no
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 7
number of relapses in the past 2 years: 1
duration since last relapse (months): 10
edss score: 2.0
disease-modifying therapy: peginterferon beta-1a
number of other medications taken: 8
neurological dysfunction: new
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: yes
fs: pyramidal: no
fs: sensory: no
fs: visual: no
total dose of mp in mg: 3000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P4-M1-T0-CD19 |
| GSM8083324 |
patient C2P4, after first course of MP, B cells |
tissue: peripheral blood
patient id: C2P4
mp course: first
time point: after
cell population: CD19+ B cells
clinical evaluation: non-responder
percentage in pbmc: 2.2
cells per ml: 273000
purity (%): 93.0
rna integrity number: 8.3
age (years): 60
Sex: male
body weight (in kg): 97
body size (in cm): 170
body mass index: 33.6
current smoker: no
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 7
number of relapses in the past 2 years: 1
duration since last relapse (months): 10
edss score: 2.0
disease-modifying therapy: peginterferon beta-1a
number of other medications taken: 8
neurological dysfunction: new
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: unchanged
fs: sensory: unchanged
fs: visual: unchanged
total dose of mp in mg: 3000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P4-M1-T1-CD19 |
| GSM8083325 |
patient C2P5, before first course of MP, B cells |
tissue: peripheral blood
patient id: C2P5
mp course: first
time point: before
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 2.6
cells per ml: 136500
purity (%): 53.8
rna integrity number: 6.9
age (years): 59
Sex: female
body weight (in kg): 60
body size (in cm): 172
body mass index: 20.3
current smoker: yes
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 4
number of relapses in the past 2 years: 1
duration since last relapse (months): 22
edss score: 3.0
disease-modifying therapy: none
number of other medications taken: 1
neurological dysfunction: new
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: yes
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 5000
days from first to last mp application: 4
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P5-M1-T0-CD19 |
| GSM8083326 |
patient C2P5, after first course of MP, B cells |
tissue: peripheral blood
patient id: C2P5
mp course: first
time point: after
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 6.8
cells per ml: 687750
purity (%): 98.1
rna integrity number: 8.2
age (years): 59
Sex: female
body weight (in kg): 60
body size (in cm): 172
body mass index: 20.3
current smoker: yes
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 4
number of relapses in the past 2 years: 1
duration since last relapse (months): 22
edss score: 2.0
disease-modifying therapy: none
number of other medications taken: 1
neurological dysfunction: new
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: better
fs: sensory: better
fs: visual: unchanged
total dose of mp in mg: 5000
days from first to last mp application: 4
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P5-M1-T1-CD19 |
| GSM8083327 |
patient C2P6, before first course of MP, B cells |
tissue: peripheral blood
patient id: C2P6
mp course: first
time point: before
cell population: CD19+ B cells
clinical evaluation: non-responder
percentage in pbmc: 4.2
cells per ml: 546000
purity (%): 92.4
rna integrity number: 8.8
age (years): 39
Sex: female
body weight (in kg): 54
body size (in cm): 164
body mass index: 20.1
current smoker: no
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 18
number of relapses in the past 2 years: 0
duration since last relapse (months): 47
edss score: 6.5
disease-modifying therapy: dimethyl fumarate
number of other medications taken: 3
neurological dysfunction: new
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: yes
fs: sensory: no
fs: visual: no
total dose of mp in mg: 3000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P6-M1-T0-CD19 |
| GSM8083328 |
patient C2P6, after first course of MP, B cells |
tissue: peripheral blood
patient id: C2P6
mp course: first
time point: after
cell population: CD19+ B cells
clinical evaluation: non-responder
percentage in pbmc: 6.6
cells per ml: 714000
purity (%): 97.8
rna integrity number: 9.0
age (years): 39
Sex: female
body weight (in kg): 54
body size (in cm): 164
body mass index: 20.1
current smoker: no
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 18
number of relapses in the past 2 years: 0
duration since last relapse (months): 47
edss score: NA
disease-modifying therapy: dimethyl fumarate
number of other medications taken: 3
neurological dysfunction: new
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: unchanged
fs: sensory: unchanged
fs: visual: unchanged
total dose of mp in mg: 3000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P6-M1-T1-CD19 |
| GSM8083329 |
patient C2P7, before first course of MP, B cells |
tissue: peripheral blood
patient id: C2P7
mp course: first
time point: before
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 2.7
cells per ml: 215250
purity (%): 95.6
rna integrity number: 7.8
age (years): 36
Sex: male
body weight (in kg): 90
body size (in cm): NA
body mass index: NA
current smoker: NA
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 16
number of relapses in the past 2 years: 1
duration since last relapse (months): 21
edss score: 3.0
disease-modifying therapy: none
number of other medications taken: 1
neurological dysfunction: new
fs: bladder or bowel: no
fs: brainstem: yes
fs: cerebellar: no
fs: cerebral: yes
fs: pyramidal: no
fs: sensory: no
fs: visual: no
total dose of mp in mg: 5000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P7-M1-T0-CD19 |
| GSM8083330 |
patient C2P7, after first course of MP, B cells |
tissue: peripheral blood
patient id: C2P7
mp course: first
time point: after
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 2.8
cells per ml: 162750
purity (%): 93.2
rna integrity number: 7.8
age (years): 36
Sex: male
body weight (in kg): 90
body size (in cm): NA
body mass index: NA
current smoker: NA
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 16
number of relapses in the past 2 years: 1
duration since last relapse (months): 21
edss score: 3.0
disease-modifying therapy: none
number of other medications taken: 1
neurological dysfunction: new
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: better
fs: pyramidal: unchanged
fs: sensory: unchanged
fs: visual: unchanged
total dose of mp in mg: 5000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P7-M1-T1-CD19 |
| GSM8083331 |
patient C2P8, before first course of MP, B cells |
tissue: peripheral blood
patient id: C2P8
mp course: first
time point: before
cell population: CD19+ B cells
clinical evaluation: non-responder
percentage in pbmc: 3.5
cells per ml: 220500
purity (%): 95.5
rna integrity number: 8.5
age (years): 23
Sex: female
body weight (in kg): NA
body size (in cm): NA
body mass index: NA
current smoker: NA
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 0
number of relapses in the past 2 years: 1
duration since last relapse (months): 10
edss score: 2.0
disease-modifying therapy: none
number of other medications taken: 0
neurological dysfunction: new
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: no
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 3000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P8-M1-T0-CD19 |
| GSM8083332 |
patient C2P8, after first course of MP, B cells |
tissue: peripheral blood
patient id: C2P8
mp course: first
time point: after
cell population: CD19+ B cells
clinical evaluation: non-responder
percentage in pbmc: 11.0
cells per ml: 535500
purity (%): 97.3
rna integrity number: 7.5
age (years): 23
Sex: female
body weight (in kg): NA
body size (in cm): NA
body mass index: NA
current smoker: NA
study center: Greifswald
course of disease: CIS/RRMS
disease duration (years): 0
number of relapses in the past 2 years: 1
duration since last relapse (months): 10
edss score: NA
disease-modifying therapy: none
number of other medications taken: 0
neurological dysfunction: new
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: unchanged
fs: sensory: unchanged
fs: visual: unchanged
total dose of mp in mg: 3000
days from first to last mp application: 2
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C2P8-M1-T1-CD19 |
| GSM8083333 |
patient C3P1, before second course of MP, T cells |
tissue: peripheral blood
patient id: C3P1
mp course: second
time point: before
cell population: CD4+ T cells
clinical evaluation: non-responder
percentage in pbmc: 24.0
cells per ml: 225750
purity (%): 97.0
rna integrity number: 7.9
age (years): 36
Sex: female
body weight (in kg): 63
body size (in cm): 175
body mass index: 20.6
current smoker: yes
study center: Jena
course of disease: CIS/RRMS
disease duration (years): 0
number of relapses in the past 2 years: 2
duration since last relapse (months): NA
edss score: 2.5
disease-modifying therapy: dimethyl fumarate
number of other medications taken: 0
neurological dysfunction: recurring
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: no
fs: sensory: yes
fs: visual: yes
total dose of mp in mg: 10000
days from first to last mp application: 6
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C3P1-M2-T0-CD4 |
| GSM8083334 |
patient C3P1, after second course of MP, T cells |
tissue: peripheral blood
patient id: C3P1
mp course: second
time point: after
cell population: CD4+ T cells
clinical evaluation: non-responder
percentage in pbmc: 10.1
cells per ml: 315000
purity (%): 98.6
rna integrity number: 8.3
age (years): 36
Sex: female
body weight (in kg): 63
body size (in cm): 175
body mass index: 20.6
current smoker: yes
study center: Jena
course of disease: CIS/RRMS
disease duration (years): 0
number of relapses in the past 2 years: 2
duration since last relapse (months): NA
edss score: 2.5
disease-modifying therapy: dimethyl fumarate
number of other medications taken: 0
neurological dysfunction: recurring
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: unchanged
fs: sensory: better
fs: visual: worse
total dose of mp in mg: 10000
days from first to last mp application: 6
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C3P1-M2-T1-CD4 |
| GSM8083335 |
patient C4P1, before first course of MP, B cells |
tissue: peripheral blood
patient id: C4P1
mp course: first
time point: before
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 5.3
cells per ml: 336000
purity (%): 96.3
rna integrity number: 9.4
age (years): 45
Sex: male
body weight (in kg): 90
body size (in cm): 180
body mass index: 27.8
current smoker: yes
study center: Rostock
course of disease: CIS/RRMS
disease duration (years): 13
number of relapses in the past 2 years: 0
duration since last relapse (months): 166
edss score: 3.5
disease-modifying therapy: none
number of other medications taken: 0
neurological dysfunction: new
fs: bladder or bowel: no
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: yes
fs: sensory: yes
fs: visual: no
total dose of mp in mg: 5000
days from first to last mp application: 5
side effects to mp: hyperhidrosis |
Gene expression data for a patient with MS treated with methylprednisolone
C4P1-M1-T0-CD19 |
| GSM8083336 |
patient C4P1, after first course of MP, B cells |
tissue: peripheral blood
patient id: C4P1
mp course: first
time point: after
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 6.9
cells per ml: 1417500
purity (%): 96.1
rna integrity number: 8.7
age (years): 45
Sex: male
body weight (in kg): 90
body size (in cm): 180
body mass index: 27.8
current smoker: yes
study center: Rostock
course of disease: CIS/RRMS
disease duration (years): 13
number of relapses in the past 2 years: 0
duration since last relapse (months): 166
edss score: 3.5
disease-modifying therapy: none
number of other medications taken: 0
neurological dysfunction: new
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: better
fs: sensory: unchanged
fs: visual: unchanged
total dose of mp in mg: 5000
days from first to last mp application: 5
side effects to mp: hyperhidrosis |
Gene expression data for a patient with MS treated with methylprednisolone
C4P1-M1-T1-CD19 |
| GSM8083337 |
patient C4P2, before first course of MP, B cells |
tissue: peripheral blood
patient id: C4P2
mp course: first
time point: before
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: NA
cells per ml: 493500
purity (%): 94.2
rna integrity number: 8.2
age (years): 54
Sex: female
body weight (in kg): 93
body size (in cm): 173
body mass index: 31.1
current smoker: no
study center: Rostock
course of disease: SPMS
disease duration (years): 20
number of relapses in the past 2 years: 1
duration since last relapse (months): 11
edss score: 7.5
disease-modifying therapy: none
number of other medications taken: 3
neurological dysfunction: NA
fs: bladder or bowel: yes
fs: brainstem: no
fs: cerebellar: no
fs: cerebral: no
fs: pyramidal: yes
fs: sensory: no
fs: visual: no
total dose of mp in mg: 5000
days from first to last mp application: 6
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C4P2-M1-T0-CD19 |
| GSM8083338 |
patient C4P2, after first course of MP, B cells |
tissue: peripheral blood
patient id: C4P2
mp course: first
time point: after
cell population: CD19+ B cells
clinical evaluation: responder
percentage in pbmc: 0.4
cells per ml: 236250
purity (%): 42.7
rna integrity number: 8.1
age (years): 54
Sex: female
body weight (in kg): 93
body size (in cm): 173
body mass index: 31.1
current smoker: no
study center: Rostock
course of disease: SPMS
disease duration (years): 20
number of relapses in the past 2 years: 1
duration since last relapse (months): 11
edss score: 6.5
disease-modifying therapy: none
number of other medications taken: 3
neurological dysfunction: NA
fs: bladder or bowel: unchanged
fs: brainstem: unchanged
fs: cerebellar: unchanged
fs: cerebral: unchanged
fs: pyramidal: better
fs: sensory: unchanged
fs: visual: unchanged
total dose of mp in mg: 5000
days from first to last mp application: 6
side effects to mp: none |
Gene expression data for a patient with MS treated with methylprednisolone
C4P2-M1-T1-CD19 |