Gene symbol: Sorbs1

Also known as: CAP; SH3P12

Organism: Rattus norvegicus

Summary: Enables insulin receptor binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including response to activity; response to insulin; and response to monosodium L-glutamate. Located in plasma membrane. Part of insulin receptor complex. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human SORBS1 (sorbin and SH3 domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

NCBI gene ID: 686098 Ensembl:ENSRNOG00000015658 AllianceGenome:RGD:1586598


GO Annotation


Category Term ID Term description
Process GO:0005979 Regulation of glycogen biosynthetic process
Process GO:0006109 Regulation of carbohydrate metabolic process
Process GO:0006950 Response to stress
Process GO:0006996 Organelle organization
Process GO:0007010 Cytoskeleton organization
Process GO:0007015 Actin filament organization
Process GO:0007044 Cell-substrate junction assembly
Process GO:0007154 Cell communication
Process GO:0007155 Cell adhesion
Process GO:0007160 Cell-matrix adhesion
Process GO:0007165 Signal transduction
Process GO:0007166 Cell surface receptor signaling pathway
Process GO:0007167 Enzyme-linked receptor protein signaling pathway
Process GO:0007169 Transmembrane receptor protein tyrosine kinase signaling pathway
Process GO:0007267 Cell-cell signaling
Process GO:0008286 Insulin receptor signaling pathway
Process GO:0009605 Response to external stimulus
Process GO:0009719 Response to endogenous stimulus
Process GO:0009725 Response to hormone
Process GO:0009889 Regulation of biosynthetic process
Process GO:0009891 Positive regulation of biosynthetic process
Process GO:0009893 Positive regulation of metabolic process
Process GO:0009966 Regulation of signal transduction
Process GO:0009967 Positive regulation of signal transduction
Process GO:0009987 Cellular process
Process GO:0009991 Response to extracellular stimulus
Process GO:0010033 Response to organic substance
Process GO:0010243 Response to organonitrogen compound
Process GO:0010556 Regulation of macromolecule biosynthetic process
Process GO:0010557 Positive regulation of macromolecule biosynthetic process
Process GO:0010604 Positive regulation of macromolecule metabolic process
Process GO:0010646 Regulation of cell communication
Process GO:0010647 Positive regulation of cell communication
Process GO:0010675 Regulation of cellular carbohydrate metabolic process
Process GO:0010676 Positive regulation of cellular carbohydrate metabolic process
Process GO:0010827 Regulation of glucose transmembrane transport
Process GO:0010828 Positive regulation of glucose transmembrane transport
Process GO:0010906 Regulation of glucose metabolic process
Process GO:0010907 Positive regulation of glucose metabolic process
Process GO:0010962 Regulation of glucan biosynthetic process
Process GO:0014823 Response to activity
Process GO:0016043 Cellular component organization
Process GO:0019216 Regulation of lipid metabolic process
Process GO:0019222 Regulation of metabolic process
Process GO:0022607 Cellular component assembly
Process GO:0023051 Regulation of signaling
Process GO:0023052 Signaling
Process GO:0023056 Positive regulation of signaling
Process GO:0030029 Actin filament-based process
Process GO:0030036 Actin cytoskeleton organization
Process GO:0030038 Contractile actin filament bundle assembly
Process GO:0031032 Actomyosin structure organization
Process GO:0031323 Regulation of cellular metabolic process
Process GO:0031325 Positive regulation of cellular metabolic process
Process GO:0031326 Regulation of cellular biosynthetic process
Process GO:0031328 Positive regulation of cellular biosynthetic process
Process GO:0031589 Cell-substrate adhesion
Process GO:0031667 Response to nutrient levels
Process GO:0032868 Response to insulin
Process GO:0032869 Cellular response to insulin stimulus
Process GO:0032870 Cellular response to hormone stimulus
Process GO:0032879 Regulation of localization
Process GO:0032880 Regulation of protein localization
Process GO:0032881 Regulation of polysaccharide metabolic process
Process GO:0032885 Regulation of polysaccharide biosynthetic process
Process GO:0033993 Response to lipid
Process GO:0034329 Cell junction assembly
Process GO:0034330 Cell junction organization
Process GO:0034762 Regulation of transmembrane transport
Process GO:0034764 Positive regulation of transmembrane transport
Process GO:0042221 Response to chemical
Process GO:0042594 Response to starvation
Process GO:0043149 Stress fiber assembly
Process GO:0043255 Regulation of carbohydrate biosynthetic process
Process GO:0043434 Response to peptide hormone
Process GO:0043467 Regulation of generation of precursor metabolites and energy
Process GO:0044085 Cellular component biogenesis
Process GO:0045725 Positive regulation of glycogen biosynthetic process
Process GO:0045834 Positive regulation of lipid metabolic process
Process GO:0045913 Positive regulation of carbohydrate metabolic process
Process GO:0046324 Regulation of glucose import
Process GO:0046326 Positive regulation of glucose import
Process GO:0046626 Regulation of insulin receptor signaling pathway
Process GO:0046628 Positive regulation of insulin receptor signaling pathway
Process GO:0046889 Positive regulation of lipid biosynthetic process
Process GO:0046890 Regulation of lipid biosynthetic process
Process GO:0048041 Focal adhesion assembly
Process GO:0048518 Positive regulation of biological process
Process GO:0048522 Positive regulation of cellular process
Process GO:0048583 Regulation of response to stimulus
Process GO:0048584 Positive regulation of response to stimulus
Process GO:0050789 Regulation of biological process
Process GO:0050794 Regulation of cellular process
Process GO:0050896 Response to stimulus
Process GO:0051017 Actin filament bundle assembly
Process GO:0051049 Regulation of transport
Process GO:0051050 Positive regulation of transport
Process GO:0051716 Cellular response to stimulus
Process GO:0060255 Regulation of macromolecule metabolic process
Process GO:0060341 Regulation of cellular localization
Process GO:0061572 Actin filament bundle organization
Process GO:0062012 Regulation of small molecule metabolic process
Process GO:0062013 Positive regulation of small molecule metabolic process
Process GO:0065007 Biological regulation
Process GO:0070873 Regulation of glycogen metabolic process
Process GO:0070875 Positive regulation of glycogen metabolic process
Process GO:0070887 Cellular response to chemical stimulus
Process GO:0071310 Cellular response to organic substance
Process GO:0071375 Cellular response to peptide hormone stimulus
Process GO:0071417 Cellular response to organonitrogen compound
Process GO:0071495 Cellular response to endogenous stimulus
Process GO:0071840 Cellular component organization or biogenesis
Process GO:0080090 Regulation of primary metabolic process
Process GO:0095500 Acetylcholine receptor signaling pathway
Process GO:0097435 Supramolecular fiber organization
Process GO:0098926 Postsynaptic signal transduction
Process GO:0099536 Synaptic signaling
Process GO:0150115 Cell-substrate junction organization
Process GO:1900076 Regulation of cellular response to insulin stimulus
Process GO:1900078 Positive regulation of cellular response to insulin stimulus
Process GO:1901652 Response to peptide
Process GO:1901653 Cellular response to peptide
Process GO:1901698 Response to nitrogen compound
Process GO:1901699 Cellular response to nitrogen compound
Process GO:1901700 Response to oxygen-containing compound
Process GO:1901701 Cellular response to oxygen-containing compound
Process GO:1902074 Response to salt
Process GO:1903076 Regulation of protein localization to plasma membrane
Process GO:1903078 Positive regulation of protein localization to plasma membrane
Process GO:1903829 Positive regulation of protein localization
Process GO:1903909 Regulation of receptor clustering
Process GO:1904008 Response to monosodium glutamate
Process GO:1904375 Regulation of protein localization to cell periphery
Process GO:1904377 Positive regulation of protein localization to cell periphery
Process GO:1904393 Regulation of skeletal muscle acetylcholine-gated channel clustering
Process GO:1904608 Response to monosodium L-glutamate
Process GO:1905144 Response to acetylcholine
Process GO:1905145 Cellular response to acetylcholine
Process GO:1905475 Regulation of protein localization to membrane
Process GO:1905477 Positive regulation of protein localization to membrane
Process GO:2000112 Regulation of cellular macromolecule biosynthetic process
Component GO:0001725 Stress fiber
Component GO:0005622 Intracellular anatomical structure
Component GO:0005634 Nucleus
Component GO:0005737 Cytoplasm
Component GO:0005829 Cytosol
Component GO:0005856 Cytoskeleton
Component GO:0005886 Plasma membrane
Component GO:0005887 Integral component of plasma membrane
Component GO:0005899 Insulin receptor complex
Component GO:0005901 Caveola
Component GO:0005911 Cell-cell junction
Component GO:0005912 Adherens junction
Component GO:0005925 Focal adhesion
Component GO:0015629 Actin cytoskeleton
Component GO:0016020 Membrane
Component GO:0016021 Integral component of membrane
Component GO:0016363 Nuclear matrix
Component GO:0016600 Flotillin complex
Component GO:0030054 Cell junction
Component GO:0030055 Cell-substrate junction
Component GO:0031224 Intrinsic component of membrane
Component GO:0031226 Intrinsic component of plasma membrane
Component GO:0031974 Membrane-enclosed lumen
Component GO:0031981 Nuclear lumen
Component GO:0032432 Actin filament bundle
Component GO:0032991 Protein-containing complex
Component GO:0034399 Nuclear periphery
Component GO:0042641 Actomyosin
Component GO:0043226 Organelle
Component GO:0043227 Membrane-bounded organelle
Component GO:0043228 Non-membrane-bounded organelle
Component GO:0043229 Intracellular organelle
Component GO:0043231 Intracellular membrane-bounded organelle
Component GO:0043232 Intracellular non-membrane-bounded organelle
Component GO:0043233 Organelle lumen
Component GO:0043235 Receptor complex
Component GO:0044853 Plasma membrane raft
Component GO:0045121 Membrane raft
Component GO:0045202 Synapse
Component GO:0061695 Transferase complex, transferring phosphorus-containing groups
Component GO:0070013 Intracellular organelle lumen
Component GO:0070161 Anchoring junction
Component GO:0071944 Cell periphery
Component GO:0097517 Contractile actin filament bundle
Component GO:0098590 Plasma membrane region
Component GO:0098796 Membrane protein complex
Component GO:0098797 Plasma membrane protein complex
Component GO:0098802 Plasma membrane signaling receptor complex
Component GO:0098857 Membrane microdomain
Component GO:0110165 Cellular anatomical entity
Component GO:1902494 Catalytic complex
Component GO:1902911 Protein kinase complex
Component GO:1990234 Transferase complex
Function GO:0005102 Signaling receptor binding
Function GO:0005158 Insulin receptor binding
Function GO:0005488 Binding
Function GO:0005515 Protein binding
Function GO:0019899 Enzyme binding
Function GO:0019900 Kinase binding
Function GO:0019901 Protein kinase binding
Function GO:0030159 Signaling receptor complex adaptor activity
Function GO:0030674 Protein-macromolecule adaptor activity
Function GO:0031625 Ubiquitin protein ligase binding
Function GO:0035591 Signaling adaptor activity
Function GO:0044389 Ubiquitin-like protein ligase binding
Function GO:0044877 Protein-containing complex binding
Function GO:0060090 Molecular adaptor activity

Pathway annotation


Category Term ID Term description
KEGG rno03320 PPAR signaling pathway
KEGG rno04520 Adherens junction
KEGG rno04910 Insulin signaling pathway

Expression profile of Sorbs1 in omics data



ID GSE136833
Title Effects of lidocaine on the expression of rat spinal cord
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4058984 Control_1 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 6.420188437
GSM4058985 Control_2 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 6.630296699
GSM4058986 Control_3 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 6.617596789
GSM4058987 Lidocaine_1 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 7.216794774
GSM4058988 Lidocaine_2 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 6.851893999
GSM4058989 Lidocaine_3 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 7.107122998

ID GSE139220
Title Expression data from sevoflurane anesthesia treated rat
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4134285 Brain_Control_rep1 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 8.319935
GSM4134286 Brain_Control_rep2 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 8.299986
GSM4134287 Brain_Control_rep3 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 8.234624
GSM4134288 Brain_Sevoflurane_rep1 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 8.176111
GSM4134289 Brain_Sevoflurane_rep2 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 8.370247
GSM4134290 Brain_Sevoflurane_rep3 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 8.33634

ID GSE157924
Title Regulation of acupuncture on genes in brain stem
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4780973 Rattus_JSSZ(Sham) tissue: Rattus brainstem of modeling treatment: Sham 10.71865471
GSM4780974 Rattus_JXZ(Hand Acu) tissue: Rattus brainstem of modeling treatment: Hand Acu 10.62752145
GSM4780975 Rattus_MXZ(TBI) tissue: Rattus brainstem of modeling treatment: TBI 10.78472119

ID GSE1779
Title Effect of Isoflurane and LTM on basolateral amygdala
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM30790 baseline control 01 male, 275-300g 1025.0
GSM30791 baseline control 02 male, 275-300g 1341.7
GSM30792 baseline control 03 male, 275-300g 1375.7
GSM30793 baseline control 04 male, 275-300g 1620.4
GSM30794 baseline control 05 male, 275-300g 1097.9
GSM30795 baseline control 06 male, 275-300g 1209.8
GSM30796 baseline control 07 male, 275-300g 1187.3
GSM30797 baseline control 08 male, 275-300g 1207.3
GSM30798 baseline control 09 male, 275-300g 1257.1
GSM30799 pain 01 1087.4
GSM30800 pain 02 1187.9
GSM30801 pain 03 1189.9
GSM30802 pain 04 1020.5
GSM30803 pain 05 1165.7
GSM30804 FC 01 1060.7
GSM30805 FC 02 1332.2
GSM30806 FC 03 1030.2
GSM30807 FC 04 1464.1
GSM30808 FC 05 1392.9
GSM30809 IFC 01 1347.0
GSM30810 IFC 02 1374.3
GSM30811 IFC 03 1518.2
GSM30812 IFC 04 1303.1
GSM30813 IFC 05 999.5
GSM99800 isoflurane 01 male, 275-300g 1021.2
GSM99801 isoflurane 02 male, 275-300g 1071.3
GSM99802 isoflurane 03 male, 275-300g 1016.0
GSM99803 isoflurane 04 male, 275-300g 1339.8
GSM99804 isoflurane 05 male, 275-300g 1115.7

ID GSE190472
Title Study on VEGF regulation mechanism of acupuncture improving endometrial receptivity in IVF-ET
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5724271 model 21 Sex: female tissue: Uterine tissue condition: model 795.2825
GSM5724272 model 22 Sex: female tissue: Uterine tissue condition: model 518.7041
GSM5724273 model 23 Sex: female tissue: Uterine tissue condition: model 441.8095
GSM5724274 treatment31 Sex: female tissue: Uterine tissue condition: treatment 472.8224
GSM5724275 treatment32 Sex: female tissue: Uterine tissue condition: treatment 655.7088
GSM5724276 treatment33 Sex: female tissue: Uterine tissue condition: treatment 435.7089
GSM5724277 control 41 Sex: female tissue: Uterine tissue condition: control 491.278
GSM5724278 control 42 Sex: female tissue: Uterine tissue condition: control 822.2381
GSM5724279 control 43 Sex: female tissue: Uterine tissue condition: control 401.8983

ID GSE205202
Title Hepatic responses of mice and rats to equivalent acetaminophen (APAP) insult [rat]
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM6208507 Rat_Baseline_0h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 10.028819
GSM6208508 Rat_Baseline_0h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 9.658169
GSM6208509 Rat_Baseline_0h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 9.91075
GSM6208510 Rat_Baseline_0h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 9.675087
GSM6208511 Rat_Baseline_0h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 9.992788
GSM6208512 Rat_Vehicle_03h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 9.793939
GSM6208513 Rat_Vehicle_03h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 9.793333
GSM6208514 Rat_Vehicle_03h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 10.093388
GSM6208515 Rat_Vehicle_03h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 9.830195
GSM6208516 Rat_Vehicle_03h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 9.977382
GSM6208517 Rat_Vehicle_06h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 9.198338
GSM6208518 Rat_Vehicle_06h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 9.278514
GSM6208519 Rat_Vehicle_06h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 9.378262
GSM6208520 Rat_Vehicle_06h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 9.333061
GSM6208521 Rat_Vehicle_06h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 9.293365
GSM6208522 Rat_Vehicle_09h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 9.458676
GSM6208523 Rat_Vehicle_09h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 9.029793
GSM6208524 Rat_Vehicle_09h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 9.240241
GSM6208525 Rat_Vehicle_09h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 9.285806
GSM6208526 Rat_Vehicle_09h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 9.322881
GSM6208527 Rat_Vehicle_24h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 9.179691
GSM6208528 Rat_Vehicle_24h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 9.136749
GSM6208529 Rat_Vehicle_24h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 9.448373
GSM6208530 Rat_Vehicle_24h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 9.572489
GSM6208531 Rat_Vehicle_24h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 9.3435
GSM6208532 Rat_APAP_03h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 9.951934
GSM6208533 Rat_APAP_03h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 9.698143
GSM6208534 Rat_APAP_03h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 9.992354
GSM6208535 Rat_APAP_03h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 10.043281
GSM6208536 Rat_APAP_03h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 9.638928
GSM6208537 Rat_APAP_06h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 9.821971
GSM6208538 Rat_APAP_06h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 10.145264
GSM6208539 Rat_APAP_06h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 9.515451
GSM6208540 Rat_APAP_06h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 9.545638
GSM6208541 Rat_APAP_06h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 9.411282
GSM6208542 Rat_APAP_09h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 9.370197
GSM6208543 Rat_APAP_09h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 9.597959
GSM6208544 Rat_APAP_09h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 9.532376
GSM6208545 Rat_APAP_09h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 9.56499
GSM6208546 Rat_APAP_09h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 9.569655
GSM6208547 Rat_APAP_24h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 9.761699
GSM6208548 Rat_APAP_24h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 9.276812
GSM6208549 Rat_APAP_24h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 10.042363
GSM6208550 Rat_APAP_24h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 9.473144
GSM6208551 Rat_APAP_24h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 9.607738

ID GSE48025
Title Affymetrix Chip Data of the Transcriptome of the Rheumatoid Arthritis Rat Model Treated with Acupuncture (Affymetrix, mRNA, batch1)
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1165929 RAT_NORA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 6.082624327
GSM1165930 RAT_NORA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 6.000771303
GSM1165931 RAT_RA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 5.730347395
GSM1165932 RAT_RA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 5.801988938
GSM1165933 RAT_NORA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 5.874373685
GSM1165934 RAT_NORA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 6.088187117
GSM1165935 RAT_AP_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 6.567233857
GSM1165936 RAT_AP_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 5.957499625
GSM1165937 RAT_MTX_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 6.151900298
GSM1165938 RAT_MTX_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 6.028473709
GSM1165939 RAT_ANE_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 6.386214451
GSM1165940 RAT_ANE_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 5.680937761
GSM1165941 RAT_PLA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 5.862954847
GSM1165942 RAT_PLA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 6.407706867
GSM1165943 RAT_NORA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 6.144795118
GSM1165944 RAT_NORA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 6.225983525
GSM1165945 RAT_AP_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 7.002306836
GSM1165946 RAT_AP_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 5.96493958
GSM1165947 RAT_MTX_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 6.302938494
GSM1165948 RAT_MTX_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 6.136355864
GSM1165949 RAT_ANE_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 6.088551229
GSM1165950 RAT_ANE_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 6.21914666
GSM1165951 RAT_PLA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 5.994633817
GSM1165952 RAT_PLA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 5.54361495

ID GSE58456
Title Affymetrix Chip Data of the Transcriptome of the Rheumatoid Arthritis Rat Model Treated with Acupuncture (Affymetrix, mRNA, batch 2)
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1693996 Peripheral blood mononuclear cells from NORA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 286.957984
GSM1693997 Peripheral blood mononuclear cells from NORA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 299.5712701
GSM1693998 Peripheral blood mononuclear cells from NORA before therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 583.7387398
GSM1693999 Peripheral blood mononuclear cells from RA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 181.1328368
GSM1694000 Peripheral blood mononuclear cells from RA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 217.0352273
GSM1694001 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 254.1775841
GSM1694002 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 197.50027
GSM1694003 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 274.8753111
GSM1694004 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 280.3526734
GSM1694005 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 293.4571872
GSM1694006 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 244.3001811
GSM1694007 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 238.029828
GSM1694008 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 302.9671676
GSM1694009 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 212.7254642

ID GSE58460
Title Rheumatoid Arthritis Rat Model Treated with Acupuncture
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1165929 RAT_NORA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 6.082624327
GSM1165930 RAT_NORA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 6.000771303
GSM1165931 RAT_RA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 5.730347395
GSM1165932 RAT_RA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 5.801988938
GSM1165933 RAT_NORA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 5.874373685
GSM1165934 RAT_NORA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 6.088187117
GSM1165935 RAT_AP_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 6.567233857
GSM1165936 RAT_AP_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 5.957499625
GSM1165937 RAT_MTX_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 6.151900298
GSM1165938 RAT_MTX_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 6.028473709
GSM1165939 RAT_ANE_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 6.386214451
GSM1165940 RAT_ANE_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 5.680937761
GSM1165941 RAT_PLA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 5.862954847
GSM1165942 RAT_PLA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 6.407706867
GSM1165943 RAT_NORA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 6.144795118
GSM1165944 RAT_NORA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 6.225983525
GSM1165945 RAT_AP_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 7.002306836
GSM1165946 RAT_AP_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 5.96493958
GSM1165947 RAT_MTX_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 6.302938494
GSM1165948 RAT_MTX_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 6.136355864
GSM1165949 RAT_ANE_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 6.088551229
GSM1165950 RAT_ANE_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 6.21914666
GSM1165951 RAT_PLA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 5.994633817
GSM1165952 RAT_PLA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 5.54361495
GSM1412003 RAT_NORA_T0_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412004 RAT_NORA_T0_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412005 RAT_RA_T0_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412006 RAT_RA_T0_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412007 RAT_NORA_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412008 RAT_NORA_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412009 RAT_AP_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412010 RAT_AP_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412011 RAT_MTX_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412012 RAT_MTX_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412013 RAT_ANE_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412014 RAT_ANE_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412015 RAT_PLA_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412016 RAT_PLA_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412017 RAT_NORA_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412018 RAT_NORA_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412019 RAT_AP_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412020 RAT_AP_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412021 RAT_MTX_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412022 RAT_MTX_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412023 RAT_ANE_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412024 RAT_ANE_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412025 RAT_PLA_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412026 RAT_PLA_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412027 RAT_RA_T0_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412028 RAT_RA_T0_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412029 RAT_AP_1h_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412030 RAT_AP_1h_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412031 RAT_PLA_1h_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412032 RAT_PLA_1h_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412033 RAT_AP_34d_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412034 RAT_AP_34d_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412035 RAT_PLA_34d_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412036 RAT_PLA_34d_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1693996 Peripheral blood mononuclear cells from NORA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therap 286.957984
GSM1693997 Peripheral blood mononuclear cells from NORA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 299.5712701
GSM1693998 Peripheral blood mononuclear cells from NORA before therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 583.7387398
GSM1693999 Peripheral blood mononuclear cells from RA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 181.1328368
GSM1694000 Peripheral blood mononuclear cells from RA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 217.0352273
GSM1694001 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 254.1775841
GSM1694002 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therap 197.50027
GSM1694003 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 274.8753111
GSM1694004 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 280.3526734
GSM1694005 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 293.4571872
GSM1694006 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 244.3001811
GSM1694007 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 238.029828
GSM1694008 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 302.9671676
GSM1694009 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 212.7254642

ID GSE8911
Title Skeletal muscle after fine needle stimulation
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM225891 Skeletal muscle sample from fine needle-stimulated hindlimb Strain: Lewis, Gender: Male, Body Weight: 275g, Tissue: Skeletal muscle sample from fine nnedle-stimulated hindlimb 279.237
GSM225892 Skeletal muscle sample from control hindlimb Strain: Lewis, Gender: Male, Body weight: 275g, Tissue: skeletal muscle sample from non fine needle-stimulated hindlimb 337.071