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Acupuncture Anesthesia related Indicator

This module allows for the query of associated research on acupuncture anesthesia-related record indicators, including clinical and animal model studies. It provides information on potential interaction molecules, such as the String PPI interaction network and GO functional/pathway annotations. Additionally, if existing omics data have detected these molecules, the module will display the changes in omics levels related to acupuncture research.


Demo
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Acupuncture anesthesia surgery knowledge graph query
Keyword：Craniotomy

Summary of Craniotomy knowledge graph

Acupoint selection


PMID 11789276
Acupoint Code Source Group
shenmen TF4 Triangular Fossa ear
pizhixia AT4 Antitragus ear
Quanliao SI18 Small Intestine Meridian of Hand-Taiyang body
Hegu LI4 Large Intestine Meridian of Hand-Yangming body
Zhigou TE6 Sanjiao Meridian of Hand-Shaoyang body
Side
Description

PMID 28254101
Acupoint Code Source Group
Fengchi GB20 Gallbladder Meridian of Foot-Shaoyang body
Shangguan GB3 Gallbladder Meridian of Foot-Shaoyang body
Yangbai GB14 Gallbladder Meridian of Foot-Shaoyang body
Naokong GB19 Gallbladder Meridian of Foot-Shaoyang body
Side
Description Acupuncture points GB-3, GB-14, GB- 19, and GB-20 were used

PMID 25169910
Acupoint Code Source Group
Hegu LI4 Large Intestine Meridian of Hand-Yangming body
Waiguan TE5 Sanjiao Meridian of Hand-Shaoyang body
Zusanli ST36 Stomach Meridian of Foot-Yangming body
Taichong LR3 Liver Meridian of Foot-Jueyin body
Jinmen BL63 Bladder Meridian of Foot-Taiyang body
Qiuxu GB40 Gallbladder Meridian of Foot-Shaoyang body
Side the same side as the craniotomy
Description In Group A, the acupuncture needles (0.25×40 mm) wereinserted into acupoints at LI4 (Hegu), SJ5 (WaiGuan), BL63 (JinMen), LR3 (Tai-Chong), ST36 (ZuSanLi) and GB40 (QiuXu) on the same side as the craniotomy. For LI4, SJ5, BL63, LR3, ST36, and GB40, each acupuncture point was treated with oneneedle. LI4 and SJ5, BL63 and LR3, as well as ST36 and GB40, were connected inpairs to the acupuncture point nerve stimulator.

PMID 23315447
Acupoint Code Source Group
Hegu LI4 Large Intestine Meridian of Hand-Yangming body
Waiguan TE5 Sanjiao Meridian of Hand-Shaoyang body
Jinmen BL63 Bladder Meridian of Foot-Taiyang body
Taichong LR3 Liver Meridian of Foot-Jueyin body
Zusanli ST36 Stomach Meridian of Foot-Yangming body
Qiuxu GB40 Gallbladder Meridian of Foot-Shaoyang body
Tianzhu BL10 Bladder Meridian of Foot-Taiyang body
Fengchi GB20 Gallbladder Meridian of Foot-Shaoyang body
Cuanzhu BL2 Bladder Meridian of Foot-Taiyang body
Side the same side as the craniotomy
Description In group A, EA was applied to LI4 (Hegu), TE5 (Waiguan), BL63 (Jinme), LR3 (Taichong), ST36 (Zusanli), GB40 (Qiuxu), BL10 (Tianzhu), GB20 (Fengchi), BL2 (Cuanzhu) and EX-HN4 (Yuyao) on the same side as the craniotomy.Group S was a sham acupuncture point group. In this group, EA was applied at 9 and 12 Cun above BL60 (Kunlun), 7 and 10 Cun above KI3 (Taixi) and 7 and 9 Cun above HT7 (Shenmen) on the side of the craniotomy.

PMID 24137250
Acupoint Code Source Group
Hegu LI4 Large Intestine Meridian of Hand-Yangming body
Waiguan TE5 Sanjiao Meridian of Hand-Shaoyang body
Jinmen BL63 Bladder Meridian of Foot-Taiyang body
Taichong LR3 Liver Meridian of Foot-Jueyin body
Zusanli ST36 Stomach Meridian of Foot-Yangming body
Qiuxu GB40 Gallbladder Meridian of Foot-Shaoyang body
Tianzhu BL10 Bladder Meridian of Foot-Taiyang body
Fengchi GB20 Gallbladder Meridian of Foot-Shaoyang body
Cuanzhu BL2 Bladder Meridian of Foot-Taiyang body
Side the same side as the craniotomy
Description EA was applied to Hegu (LI4), Waiguan (TE5), Jinme (BL63), Taichong (LR3), Zusanli (ST36), Qiuxu (GB40), Tianzhu (BL10), Fengchi (GB20), Cuanzhu (BL2) and Yuyao (EX-HN4) on the side with the craniotomy. Group S was a sham acupoints group. In this group, EA was applied at 9 and 12 Cun above Kunlun (BL60), 7 and 10 Cun above Taixi (KI3) and 7 and 9 Cun above Shenmen (HT7) on the side with the craniotomy.

PMID 22732720
Acupoint Code Source Group
Neiguan PC6 Pericardium Meridian of Hand-Jueyin body
Side dominant side
Description patients received TEAS at P6 on the dominant side


Stimulation method


PMID 28254101
Model Manufacturer Frequency Waveform Strength Induction Time
Hwato 6-channel Needle Stimulator Hwato,Suzhou Medical Appliances Co., Ltd., Suzhou, China 50 Hz - 12 mA 1 h

PMID 25169910
Model Manufacturer Frequency Waveform Strength Induction Time
LH202H HANS Beijing Huawei Co, Ltd., Beijing, China 2/100 Hz disperse-dense wave the level of maximum tolerance for each patient from the induction of anesthesia until the end of the operation

PMID 23315447
Model Manufacturer Frequency Waveform Strength Induction Time
LH202H HANS Beijing Huawei Co, Ltd., Beijing, China 2/100 Hz dense-dispersed wave at the level ofmaximal tolerance of each patient from the induction of anaesthesia until the end of the operation

PMID 24137250
Model Manufacturer Frequency Waveform Strength Induction Time
LH202H Beijing Huawei Co, Ltd., Beijing, China 2/100 Hz disperse-dense wave at the level ofmaximal tolerance of each patient EAS lasted from the induction of anesthesia until the end of surgery

PMID 22732720
Model Manufacturer Frequency Waveform Strength Induction Time
HANS Beijing Huawei Co, Ltd., Beijing, China 2/100 Hz alternating wave 2 mA 30 minutes before the induction of anesthesia and lasted up to 24 hours postoperatively


Auxiliary medication


PMID 28254101
Auxiliary Medication Prior to the incision, local anesthesia with lignocaine was used only to infiltrate the skin (lignocaine 2 mg/kg). No general anesthesia was Used throughout the surgery.

PMID 25169910
Auxiliary Medication Following pre-oxygenation, anesthesia was induced in both groups with an IV infusion of sufentanil 0.3 g/kg and propofol 2 mg/kg. A tracheal intubation was facilitated with IV vecuronium 0.1 mg/kg. General anesthesia was initially maintained with sevoflurane, 2% in oxygen at 2L/min. At the end of the operation, sevoflurane was discontinued and the intravenous PCIA pump was connected. The PCIA device was programmed and contained 10 g/kg fentanyl and 8 mg ondansetron with normal saline for a total of 100 mL without basal infusion. Supplemental bolus doses of 1 mL could be administered with a minimal lockout interval of 15 min and a maximum hourly dose of 4 mL if the patient was unable to achieve adequate pain relief from the PCIA device.

PMID 23315447
Auxiliary Medication propofol and sufentanil. The induction plasma concentration of propofol was 5 μg/ml and of sufentanil was 0.5ng/ml. When the patients were unconscious, the plasma concentration of propofol was reduced to 3.2 μg/ml, the concentration of sufentanyl was reduced to 0.3 ng/ml and vecuronium bromide 0.1 mg/kg was administered. After muscle relaxation, tracheal intubation was performed. Intermittent administration of 0.05 mg/kg vecuronium bromide was given to maintain muscle relaxation. The concentration of sufentanil was adjusted to maintain the mean arterial pressure (MAP) and HR in the basic range of +10% to −20%. In cases of hypotension (MAP<20% of baseline), bradycardia (HR<50 beats/ min) or hypertension (MAP>10% of baseline values), 6 mg ephedrine, 0.5 mg atropine or 0.2–0.5 mg nicardipine, respectively, was administered.

PMID 24137250
Auxiliary Medication The induction plasma concentration of propofol was 5 μg/ml, and that of sufentanil was 0.5 ng/ml. While the patient was unconscious, the plasma concentration of propofol was reduced to 3.2 μg/ml and that of sufentanil to 0.3 ng/ml, and vecuronium bromide 0.1 mg/kg was administered at the same time. After muscle relaxation, tracheal intubation was performed. Vecuronium bromide (0.05 mg/kg) was intermittently administered performed to maintain muscle relaxation. Sufentanil concentration was adjusted to maintain the mean arterial pressure (MAP) and HR in the basic range of +10% to −20%. In cases of hypotension (MAP <20% of baseline), bradycardia (HR <50 beats/min) or hypertension (MAP >10% of baseline values), 6 mg ephedrine, 0.5 mg atropine or 0.2–0.5 mg nicardipine was administered, respectively.

PMID 22732720
Auxiliary Medication The anesthetic technique was standardized as follows: patients were premedicated with midazolam intravenously (IV) (up to 2 mg), and anesthesia was induced with propofol (1 to 2 mg/kg), fentanyl (3 to 5 mg/kg), and a muscle relaxant of choice (cisatracurium, rocuronium, vecuronium). Anesthesia was maintained using sevoflurane (1.8% to 2.5%), remifentanil (0.05 to 0.2mg/kg/ min), and intermittent fentanyl (4mg/kg). All patients received dexamethasone IV (10mg) after induction and ondansetron IV (4 mg) before skin closure.


Indicator


PMID 28254101
Indicator Computed tomography(CT) |

PMID 25169910
Indicator Postoperative pain scores | Postoperative Nausea and Vomiting(PONV) | Degree of dizziness and appetite | Consumption of analgesic of PCIA | Antiemetic dosage |

PMID 23315447
Indicator TNF-α | IL-8 | IL-10 | IgM | IgA | IgG | Full blood count |

PMID 24137250
Indicator TNF-α | IL-8 | IL-10 | IgM | IgA | IgG |

PMID 22732720
Indicator Postoperative Nausea and Vomiting(PONV) | The need for antiemetic rescue |



Treemap Table
Group Node Sample Count Surgery
Indicator Computed tomography(CT) 1 Craniotomy
Indicator TNF-α 56 Craniotomy
Indicator IL-8 56 Craniotomy
Indicator IL-10 56 Craniotomy
Indicator IgM 56 Craniotomy
Indicator IgA 56 Craniotomy
Indicator IgG 56 Craniotomy
Indicator Full blood count 56 Craniotomy
Acupoint Fengchi|GB20 57 Craniotomy
Acupoint Shangguan|GB3 1 Craniotomy
Acupoint Yangbai|GB14 1 Craniotomy
Acupoint Naokong|GB19 1 Craniotomy
Acupoint Hegu|LI4 56 Craniotomy
Acupoint Waiguan|TE5 56 Craniotomy
Acupoint Jinmen|BL63 56 Craniotomy
Acupoint Taichong|LR3 56 Craniotomy
Acupoint Zusanli|ST36 56 Craniotomy
Acupoint Qiuxu|GB40 56 Craniotomy
Acupoint Tianzhu|BL10 56 Craniotomy
Acupoint Cuanzhu|BL2 56 Craniotomy
Acupoint Yuyao|EX-HN4 56 Craniotomy
Hegu|LI4 the same side as the craniotomy 56 Craniotomy
Waiguan|TE5 the same side as the craniotomy 56 Craniotomy
Jinmen|BL63 the same side as the craniotomy 56 Craniotomy
Taichong|LR3 the same side as the craniotomy 56 Craniotomy
Zusanli|ST36 the same side as the craniotomy 56 Craniotomy
Qiuxu|GB40 the same side as the craniotomy 56 Craniotomy
Tianzhu|BL10 the same side as the craniotomy 56 Craniotomy
Fengchi|GB20 the same side as the craniotomy 56 Craniotomy
Cuanzhu|BL2 the same side as the craniotomy 56 Craniotomy
Yuyao|EX-HN4 the same side as the craniotomy 56 Craniotomy
Stimulation_Method EA 57 Craniotomy
EA 50 Hz 1 Craniotomy
EA Hwato 6-channel Needle Stimulator 1 Craniotomy
EA dense-dispersed wave 56 Craniotomy
EA 2/100 Hz 56 Craniotomy
EA LH202H HANS 56 Craniotomy
MS 0.25×40 mm 1 Craniotomy
MS 0.7-1.5 cm 56 Craniotomy
Auxiliary_Medication Lidocaine 1 Craniotomy
Auxiliary_Medication Propofol 56 Craniotomy
Auxiliary_Medication Sufentanil 56 Craniotomy
Auxiliary_Medication Vecuronium bromide 56 Craniotomy
Auxiliary_Medication Ephedrine 56 Craniotomy
Auxiliary_Medication Atropine 56 Craniotomy
Auxiliary_Medication Nicardipine 56 Craniotomy