Overview of HTLV1 Mutation, Integration-Cistrome Factor Overlap and Target gene

Human T-cell Lymphotropic Virus Type-1 (HTLV1), or human T-lymphotropic virus type 1, also called the adult T-cell lymphoma virus type 1, is a retrovirus of the human T-lymphotropic virus (HTLV) family that has been implicated in several kinds of diseases including very aggressive adult T-cell lymphoma (ATL), HTLV-I-associated myelopathy, uveitis, Strongyloides stercoralis hyper-infection and some other diseases.
Size: ～9034 nucleotides [RefSeq: AB513134]
Encoding: CA, Tax, Gp46, Rex, 5′LTR, 3′LTR and so on
Human Disease: Infection with HBV can lead to Adult T cell leukemia/lymphoma, etc. Click here to see all HTLV1 associated human diseases

Click the blue font on the page to view detailed information.
The cistrome refers to "the set of cis-acting targets of a trans-acting factor on a genome-wide scale."

HTLV1 Mutation Info

Only show 100 info Click here to see all HTLV1 Mutation Sites

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	22947305	G232A	5′LTR	R S CI C	View
2	22947305	A184G	5′LTR	R S CI C	View
3	28420387	T5237C	Env	R S C	View
4	17067264	G8231A	Tax	R S C	View
5	17067264	C7982T	Tax	R S C	View
6	17067264	C7920T	Tax	R S C	View
7	17067264	C7401T	Tax	R S C	View
8	17067264	T7914C	Tax	R S C	View
9	28420387	A149T	P30	R S C	View
10	28420387	A3963T	Pol	R S C	View
11	28420387	A7247G	HBZ	R S C	View
12	28420387	A7247G	P30	R S C	View
13	28420387	C5593A	Env	R S C	View
14	28420387	C6903T	P12	R S C	View
15	28420387	C7962T	Tax	R S C	View
16	28420387	D140G	P30	R S C	View
17	28420387	F19L	Env	R S C	View
18	28420387	G7273A	P30	R S C	View
19	28420387	G8211A	Tax	R S C	View
20	28420387	H137Q	Env	R S C	View
21	28420387	S304N	Env	R S C	View
22	28420387	L27R	P30	R S C	View
23	28420387	P23S	P12	R S C	View
24	28420387	Q323H	Pol	R S C	View
25	26472535	151Delta11	5′LTR	R S C	View
26	26472535	T345C	5′LTR	R S C	View
27	26472535	T301C	5′LTR	R S C	View
28	26472535	T301A	5′LTR	R S C	View
29	26472535	A298G	5′LTR	R S C	View
30	26472535	C268T	5′LTR	R S C	View
31	26472535	C219T	5′LTR	R S C	View
32	28420387	A221V	HBZ	R S C	View
33	25830656	L55P	Gp46	R S C	View
34	28420387	S13P	HBZ	R S C	View
35	26472535	C219G	5′LTR	R S C	View
36	26472535	C215T	5′LTR	R S C	View
37	26472535	A207G	5′LTR	R S C	View
38	26472535	G199A	5′LTR	R S C	View
39	26472535	C167T	5′LTR	R S C	View
40	26472535	T165C	5′LTR	R S C	View
41	26472535	G153A	5′LTR	R S C	View
42	23800288	P34L	P12	R S C	View
43	23800288	C336T	HBZ	R S C	View
44	23800288	C101T	HBZ	R S C	View
45	28420387	T6908G	P30	R S C	View
46	23800288	T95I	HBZ	R S C	View
47	23800288	S9P	HBZ	R S C	View
48	23800288	R112C	HBZ	R S C	View
49	23800288	Y477H	Gp21	R S C	View
50	33835501	K184R	HBZ	R S C	View
51	33835501	I164V	HBZ	R S C	View
52	33835501	C585T	HBZ	R S C	View
53	33835501	R119Q	HBZ	R S C	View
54	33835501	P65L	HBZ	R S C	View
55	33835501	V15M	HBZ	R S C	View
56	33835501	T77C	HBZ	R S C	View
57	33835501	T138C	HBZ	R S C	View
58	33835501	G434A	HBZ	R S C	View
59	33835501	C272T	HBZ	R S C	View
60	22449200	C7401T	Tax	S C	View
61	22449200	C7920T	Tax	S C	View
62	22449200	C7982T	Tax	S C	View
63	22449200	G8231A	Tax	S C	View
64	22449200	T7914C	Tax	S C	View
65	26516904	G8392A	3′LTR	S C	View
66	26516904	G8391A	3′LTR	S C	View
67	26516904	G8381A	3′LTR	S C	View
68	26516904	G8295A	3′LTR	S C	View
69	26516904	G7431A	Tax	S C	View
70	26516904	C8718T	3′LTR	S C	View
71	26516904	C8665T	3′LTR	S C	View
72	26516904	C8606G	3′LTR	S C	View
73	26516904	C8606A	3′LTR	S C	View
74	26516904	C8420T	3′LTR	S C	View
75	26516904	C8367A	3′LTR	S C	View
76	26516904	C7933T	Tax	S C	View
77	26516904	C7398T	Tax	S C	View
78	22449200	A8367C	Tax	S C	View
79	22449200	A2661V	Tax	S C	View
80	22449200	S2744N	Tax	S C	View
81	22449200	C7410A	Tax	S C	View
82	22449200	G7431A	Tax	S C	View
83	22449200	T7476C	Tax	S C	View
84	22449200	G7527A	Tax	S C	View
85	26516904	C7383T	Tax	S C	View
86	26516904	A8828G	3′LTR	S C	View
87	26516904	A8509G	3′LTR	S C	View
88	22449200	A8288G	Tax	S C	View
89	22449200	A8002G	Tax	S C	View
90	22449200	C8066G	Tax	S C	View
91	22449200	A8109G	Tax	S C	View
92	22449200	G8128A	Tax	S C	View
93	33539355	L19F	Gp46	S CI C	View
94	22449200	C8184T	Tax	S C	View
95	22449200	C8191T	Tax	S C	View
96	22449200	T8232C	Tax	S C	View
97	26472535	G126C	5′LTR	S C	View
98	26472535	G306A	5′LTR	S C	View
99	26472535	G126T	5′LTR	S C	View
100	26472535	G306C	5′LTR	S C	View

HTLV1 Overlap Info between Viral Integration Fragments and Cistrome Factors

Click to see statistics heatmap of VIS-Factor Overlap in the human genome of HTLV1

Click to see histogram of VIS-Factor Overlap by chromosome of HTLV1

Click to see the overlap count of three factors and HTLV1 intergration fragments on the human chromosomes

Only show 100 info Click here to see all HTLV1 Integration Sites

DVID	Chromosome	Histone Modification	Transcription Factor Binding Site	Chromatin Accessibility	Sum of Overlapped Records	Detail
6100002	chr1	3854	9474	2113	15441	View
6100062	chr1	2350	7942	2090	12382	View
6400005	chr1	4522	2460	1276	8258	View
6000031	chr1	3978	2549	1464	7991	View
6000047	chr1	4112	1394	1021	6527	View
6000054	chr1	3675	1747	732	6154	View
6000063	chr1	2791	1709	1282	5782	View
6000065	chr1	996	2628	2080	5704	View
6000066	chr1	4167	1076	439	5682	View
6000070	chr1	2539	1638	1377	5554	View
6000071	chr1	2602	1746	1205	5553	View
6000085	chr1	3060	1258	767	5085	View
6000086	chr1	2566	1546	945	5057	View
6000087	chr1	2445	1002	1583	5030	View
6000105	chr1	1309	1601	1675	4585	View
6000107	chr1	2439	1021	1090	4550	View
6100077	chr1	3251	717	348	4316	View
6000121	chr1	3278	664	294	4236	View
6000124	chr1	2165	1391	628	4184	View
6000154	chr1	2440	605	619	3664	View
6000159	chr1	3139	242	214	3595	View
6000162	chr1	2254	768	529	3551	View
6000167	chr1	2939	368	141	3448	View
6000171	chr1	3066	207	114	3387	View
6000177	chr1	2330	519	459	3308	View
6000179	chr1	885	1158	1255	3298	View
6000192	chr1	2047	939	174	3160	View
6000220	chr1	2711	122	70	2903	View
6000222	chr1	2374	193	317	2884	View
6000233	chr1	2247	293	191	2731	View
6000242	chr1	2551	81	29	2661	View
6000240	chr1	2469	115	75	2659	View
6000256	chr1	2010	316	246	2572	View
6000259	chr1	2423	93	9	2525	View
6000267	chr1	2107	295	74	2476	View
6000285	chr1	1819	302	226	2347	View
6000304	chr1	603	857	781	2241	View
6000308	chr1	2124	39	29	2192	View
6000315	chr1	2107	37	4	2148	View
6000322	chr1	1396	343	393	2132	View
6000323	chr1	1758	210	155	2123	View
6000325	chr1	56	1088	969	2113	View
6000329	chr1	1857	121	117	2095	View
6000332	chr1	1513	257	307	2077	View
6000341	chr1	408	872	755	2035	View
6000349	chr1	1778	96	138	2012	View
6000358	chr1	1784	198	9	1991	View
6100069	chr1	1225	444	273	1942	View
6000383	chr1	611	503	715	1829	View
6000384	chr1	96	1025	701	1822	View
6000396	chr1	1224	256	286	1766	View
6000401	chr1	368	674	703	1745	View
6000411	chr1	1027	366	313	1706	View
6000442	chr1	1257	135	200	1592	View
6000456	chr1	1117	256	185	1558	View
6000464	chr1	7	915	590	1512	View
6000486	chr1	1130	186	127	1443	View
6000487	chr1	592	460	383	1435	View
6000500	chr1	318	477	612	1407	View
6000505	chr1	516	679	201	1396	View
6000512	chr1	282	443	636	1361	View
6000515	chr1	30	794	531	1355	View
6000578	chr1	959	117	122	1198	View
6000614	chr1	772	321	35	1128	View
6000617	chr1	29	655	442	1126	View
6000619	chr1	138	433	541	1112	View
6000668	chr1	899	69	31	999	View
6000680	chr1	682	161	151	994	View
6000688	chr1	45	692	241	978	View
6000690	chr1	13	667	296	976	View
6100063	chr1	184	534	221	939	View
6000716	chr1	788	59	87	934	View
6100001	chr1	181	529	199	909	View
6000758	chr1	753	68	60	881	View
6000764	chr1	278	333	265	876	View
6000783	chr1	534	160	166	860	View
6000790	chr1	789	56	8	853	View
6000810	chr1	340	282	211	833	View
6000821	chr1	448	315	54	817	View
6000826	chr1	620	61	132	813	View
6000841	chr1	485	222	92	799	View
6000842	chr1	787	11		798	View
6000866	chr1	485	179	101	765	View
6000874	chr1	619	39	103	761	View
6000903	chr1	10	564	155	729	View
6000944	chr1	659	32	4	695	View
6000955	chr1	680	4		684	View
6000978	chr1	639	22		661	View
6000987	chr1	42	242	372	656	View
6000990	chr1	550	48	57	655	View
6000991	chr1	43	242	370	655	View
6001032	chr1	16	526	94	636	View
6001033	chr1	200	159	276	635	View
6001034	chr1	465	131	31	627	View
6001061	chr1	475	78	56	609	View
6001103	chr1	389	64	130	583	View
6001109	chr1	337	161	81	579	View
6001123	chr1	34	379	164	577	View
6001133	chr1	415	50	106	571	View
6001165	chr1	127	307	121	555	View

HTLV1 Target Gene Info

Click to see correlation between gene expression and proportions of infiltrating immune cells of HTLV1

Only show 100 info Click here to see all HTLV1 Target Gene

ID	Target gene	Virus	Gene Function	Literature Count	Detail
1	TMPRSS11A	HTLV1	Suppressor gene	1	View
2	XRCC5	HTLV1	Suppressor gene	2	View
3	TNFAIP3	HTLV1	Suppressor gene	1	View
4	WWOX	HTLV1	Suppressor gene	3	View
5	WNT7A	HTLV1	Suppressor gene	1	View
6	WNT11	HTLV1	Suppressor gene	1	View
7	WNK2	HTLV1	Suppressor gene	2	View
8	WIF1	HTLV1	Suppressor gene	1	View
9	ZBTB4	HTLV1	Suppressor gene	1	View
10	ZBTB7C	HTLV1	Suppressor gene	4	View
11	TOM1L2	HTLV1	Suppressor gene	2	View
12	TP53	HTLV1	Suppressor gene	2	View
13	TP53BP1	HTLV1	Suppressor gene	1	View
14	TP53BP2	HTLV1	Suppressor gene	1	View
15	ZDHHC2	HTLV1	Suppressor gene	1	View
16	TMEFF2	HTLV1	Suppressor gene	1	View
17	ZFHX3	HTLV1	Suppressor gene	5	View
18	TPTE2	HTLV1	Suppressor gene	2	View
19	ZHX2	HTLV1	Suppressor gene	1	View
20	ZMYND11	HTLV1	Suppressor gene	1	View
21	VSNL1	HTLV1	Suppressor gene	2	View
22	TRIM24	HTLV1	Suppressor gene	1	View
23	TRIM3	HTLV1	Suppressor gene	1	View
24	ZNF185	HTLV1	Suppressor gene	1	View
25	VPS53	HTLV1	Suppressor gene	2	View
26	TRIM62	HTLV1	Suppressor gene	1	View
27	THRB	HTLV1	Suppressor gene	1	View
28	ZNF292	HTLV1	Suppressor gene	3	View
29	TGFBR3	HTLV1	Suppressor gene	2	View
30	TGFBR2	HTLV1	Suppressor gene	1	View
31	VEZT	HTLV1	Suppressor gene	2	View
32	TFAP2A	HTLV1	Suppressor gene	1	View
33	TSC22D1	HTLV1	Suppressor gene	4	View
34	TSG101	HTLV1	Suppressor gene	2	View
35	TET2	HTLV1	Suppressor gene	1	View
36	UVRAG	HTLV1	Suppressor gene	3	View
37	TDRG1	HTLV1	Suppressor gene	1	View
38	TCHP	HTLV1	Suppressor gene	1	View
39	USP12	HTLV1	Suppressor gene	1	View
40	TCF4	HTLV1	Suppressor gene	1	View
41	TBX5	HTLV1	Suppressor gene	1	View
42	TBL2	HTLV1	Suppressor gene	1	View
43	UNC5D	HTLV1	Suppressor gene	3	View
44	UNC5C	HTLV1	Suppressor gene	4	View
45	UNC5B	HTLV1	Suppressor gene	2	View
46	UFL1	HTLV1	Suppressor gene	1	View
47	UBE4B	HTLV1	Suppressor gene	1	View
48	UBIAD1	HTLV1	Suppressor gene	1	View
49	UHRF2	HTLV1	Suppressor gene	1	View
50	UIMC1	HTLV1	Suppressor gene	1	View
51	LSAMP	HTLV1	Suppressor gene	3	View
52	MAP4K1	HTLV1	Suppressor gene	1	View
53	MAP3K4	HTLV1	Suppressor gene	2	View
54	MAP2K4	HTLV1	Suppressor gene	1	View
55	LRP1B	HTLV1	Suppressor gene	4	View
56	MAD1L1	HTLV1	Suppressor gene	2	View
57	LRIG1	HTLV1	Suppressor gene	3	View
58	BRCA2	HTLV1	Suppressor gene	1	View
59	AJAP1	HTLV1	Suppressor gene	2	View
60	CACNA2D3	HTLV1	Suppressor gene	4	View
61	AHRR	HTLV1	Suppressor gene	2	View
62	AHNAK	HTLV1	Suppressor gene	2	View
63	ATM	HTLV1	Suppressor gene	1	View
64	ATMIN	HTLV1	Suppressor gene	1	View
65	CADM1	HTLV1	Suppressor gene	1	View
66	CEBPA	HTLV1	Suppressor gene	1	View
67	CADM2	HTLV1	Suppressor gene	4	View
68	CADM4	HTLV1	Suppressor gene	1	View
69	ASS1	HTLV1	Suppressor gene	1	View
70	CDKN2C	HTLV1	Suppressor gene	1	View
71	CDKN2A	HTLV1	Suppressor gene	2	View
72	AFAP1L2	HTLV1	Suppressor gene	1	View
73	CDH4	HTLV1	Suppressor gene	3	View
74	CAMTA1	HTLV1	Suppressor gene	2	View
75	ARNTL	HTLV1	Suppressor gene	2	View
76	CDH13	HTLV1	Suppressor gene	3	View
77	ANAPC1	HTLV1	Suppressor gene	1	View
78	CDH11	HTLV1	Suppressor gene	1	View
79	CDC73	HTLV1	Suppressor gene	1	View
80	AXIN2	HTLV1	Suppressor gene	1	View
81	ADAMTS9-AS2	HTLV1	Suppressor gene	2	View
82	ADAMTS9	HTLV1	Suppressor gene	2	View
83	ADAMTS18	HTLV1	Suppressor gene	1	View
84	ARL6IP5	HTLV1	Suppressor gene	1	View
85	CD82	HTLV1	Suppressor gene	1	View
86	CHD5	HTLV1	Suppressor gene	1	View
87	CASC2	HTLV1	Suppressor gene	1	View
88	CHEK1	HTLV1	Suppressor gene	1	View
89	ACVR1C	HTLV1	Suppressor gene	1	View
90	CHEK2	HTLV1	Suppressor gene	1	View
91	CHFR	HTLV1	Suppressor gene	1	View
92	ARID2	HTLV1	Suppressor gene	2	View
93	BASP1	HTLV1	Suppressor gene	2	View
94	BBC3	HTLV1	Suppressor gene	1	View
95	CASP2	HTLV1	Suppressor gene	1	View
96	ARHGEF12	HTLV1	Suppressor gene	1	View
97	CAT	HTLV1	Suppressor gene	1	View
98	CCNC	HTLV1	Suppressor gene	1	View
99	BCL6B	HTLV1	Suppressor gene	1	View
100	ANP32A	HTLV1	Suppressor gene	1	View


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