Gene symbol: Dkk1

Organism: Rattus norvegicus

Summary: Predicted to enable co-receptor binding activity; low-density lipoprotein particle receptor binding activity; and receptor antagonist activity. Involved in negative regulation of ossification and positive regulation of neuron death. Located in extracellular space. Used to study visual epilepsy. Human ortholog(s) of this gene implicated in anodontia. Orthologous to human DKK1 (dickkopf WNT signaling pathway inhibitor 1). [provided by Alliance of Genome Resources, Apr 2022]

NCBI gene ID: 293897 EnsemblRapid:ENSRNOG00000048688 AllianceGenome:RGD:1307313


Expression profile of Dkk1 in omics data



ID GSE100499
Title Exploring acupuncture mechanism in preconditioning of IRI
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM2685201 MX1 tissue: Myocardium gender: male 3.1892264
GSM2685202 MX2 tissue: Myocardium gender: female 2.7953506
GSM2685203 MX3 tissue: Myocardium gender: female 2.3330942
GSM2685204 MX4 tissue: Myocardium gender: male 2.79441845
GSM2685205 DZ1 tissue: Myocardium gender: male 2.70567
GSM2685206 DZ2 tissue: Myocardium gender: male 2.3384084
GSM2685207 DZ3 tissue: Myocardium gender: female 2.749996
GSM2685208 DZ4 tissue: Myocardium gender: female 2.9112526499999998
GSM2685209 JJ1 tissue: Myocardium gender: male 2.9153793
GSM2685210 JJ2 tissue: Myocardium gender: female 3.08699705
GSM2685211 JJ3 tissue: Myocardium gender: female 3.3224058000000003
GSM2685212 JJ4 tissue: Myocardium gender: male 3.75718435
GSM2685213 NG1 tissue: Myocardium gender: male 4.3979164
GSM2685214 NG2 tissue: Myocardium gender: female 2.9507221
GSM2685215 NG3 tissue: Myocardium gender: male 4.5871065
GSM2685216 NG4 tissue: Myocardium gender: female 3.22660995
GSM2685217 YL1 tissue: Myocardium gender: male 5.3103042
GSM2685218 YL2 tissue: Myocardium gender: male 2.740888
GSM2685219 YL3 tissue: Myocardium gender: female 3.59092685
GSM2685220 YL4 tissue: Myocardium gender: female 4.907129299999999
GSM2685221 QC1 tissue: Myocardium gender: male 2.4375904
GSM2685222 QC2 tissue: Myocardium gender: male 3.23285465
GSM2685223 QC3 tissue: Myocardium gender: female 2.973493
GSM2685224 QC4 tissue: Myocardium gender: female 2.93302285

ID GSE136833
Title Effects of lidocaine on the expression of rat spinal cord
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4058984 Control_1 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 2.841618642
GSM4058985 Control_2 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 2.720814652
GSM4058986 Control_3 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 2.67211779
GSM4058987 Lidocaine_1 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 2.626362522
GSM4058988 Lidocaine_2 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 2.949250427
GSM4058989 Lidocaine_3 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 2.634996783

ID GSE138454
Title Impact of inflammation on hepatic subcellular energetics in anesthetized rats
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4108997 Sample 1 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4108998 Sample 2 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4108999 Sample 3 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109000 Sample 4 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109001 Sample 5 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109002 Sample 6 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109003 Sample 7 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109004 Sample 8 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109005 Sample9 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109006 Sample10 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109007 Sample11 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109008 Sample12 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109009 Sample13 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109010 Sample14 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109011 Sample 15 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109012 Sample16 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0

ID GSE139220
Title Expression data from sevoflurane anesthesia treated rat
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4134285 Brain_Control_rep1 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 4.806862
GSM4134286 Brain_Control_rep2 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 5.094604
GSM4134287 Brain_Control_rep3 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 4.910712
GSM4134288 Brain_Sevoflurane_rep1 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 5.218487
GSM4134289 Brain_Sevoflurane_rep2 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 4.884564
GSM4134290 Brain_Sevoflurane_rep3 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 4.738247

ID GSE143895
Title GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4276356 dhsc01 strain: Sprague Dawley tissue: DHSC treatment: CCI 3.311
GSM4276357 dhsc03 strain: Sprague Dawley tissue: DHSC treatment: CCI 4.37
GSM4276358 dhsc05 strain: Sprague Dawley tissue: DHSC treatment: CCI 4.732
GSM4276359 dhsc13 strain: Sprague Dawley tissue: DHSC treatment: SHAM 4.607
GSM4276360 dhsc15 strain: Sprague Dawley tissue: DHSC treatment: SHAM 4.125

ID GSE192399
Title Gene expression of brain regions activated by sevoflurane and propofol
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5746332 LHb, Sevoflurane, 60mins brain region: the lateral habenula (LHb) treatment: Sevoflurane 3.71265
GSM5746333 LHb, O2, 60mins brain region: the lateral habenula (LHb) treatment: O2 3.51579
GSM5746334 MHb, Sevoflurane, 60mins brain region: the medial habenula (MHb) treatment: Sevoflurane 3.46643
GSM5746335 MHb, O2, 60mins brain region: the medial habenula (MHb) treatment: O2 3.62563
GSM5746336 Sol, Sevoflurane, 60mins brain region: the solitary nucleus (Sol) treatment: Sevoflurane 3.67762
GSM5746337 Sol, O2, 60mins brain region: the solitary nucleus (Sol) treatment: O2 3.3389
GSM5746338 Mve, Sevoflurane, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Sevoflurane 3.34094
GSM5746339 Mve, O2, 60mins brain region: the medial vestibular nucleus (MVe) treatment: O2 3.73775
GSM5746340 LHb, Propofol, 60mins brain region: the lateral habenula (LHb) treatment: Propofol 3.77926
GSM5746341 LHb, Intralipos, 60mins brain region: the lateral habenula (LHb) treatment: Intralipos 3.93013
GSM5746342 MHb, Propofol, 60mins brain region: the medial habenula (MHb) treatment: Propofol 4.25896
GSM5746343 MHb, Intralipos, 60mins brain region: the medial habenula (MHb) treatment: Intralipos 4.0117
GSM5746344 Sol, Propofol, 60mins brain region: the solitary nucleus (Sol) treatment: Propofol 3.55756
GSM5746345 Sol, Intralipos, 60mins brain region: the solitary nucleus (Sol) treatment: Intralipos 4.09968
GSM5746346 MVe, Propofol, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Propofol 4.12977
GSM5746347 MVe, Intralipos, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Intralipos 3.80541

ID GSE244436
Title Similarity and dissimilarity in alteration of gene expression profile associated with inhalational anesthesia between sevoflurane and desflurane
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM7816143 Liver, Control for SevoAnes tissue: liver genotype: wild type treatment: Control for SevoAnes 0.0
GSM7816144 Liver, Anesthetized with sevoflurane for 6 h tissue: liver genotype: wild type treatment: Anesthetized with sevoflurane for 6 h 0.0
GSM7816145 Liver, Control for DesAnes tissue: liver genotype: wild type treatment: Control for DesAnes 0.0
GSM7816146 Liver, Anesthetized with desflurane for 6 h tissue: liver genotype: wild type treatment: Anesthetized with desflurane for 6 h 0.002897

ID GSE53897
Title Genome-wide analysis of dorsal root ganglion (DRG) gene expression after morphine or oxycodone treatment
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1303240 DRG RVM1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.738858
GSM1303241 DRG RVM2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.552217
GSM1303242 DRG RVM3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.607016
GSM1303243 DRG RVM7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.630763
GSM1303244 DRG RVOx2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.597322
GSM1303245 DRG RVOx3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.688182
GSM1303246 DRG RVOx5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.492493
GSM1303247 DRG RVOx7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.749873
GSM1303248 DRG RVS4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.655744
GSM1303249 DRG RVS5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.699472
GSM1303250 DRG RVS6 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.653974
GSM1303251 DRG RVS7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.678003
GSM1303252 DRG RSM1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.637048
GSM1303253 DRG RSM2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.645099
GSM1303254 DRG RSM4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.580706
GSM1303255 DRG RSM5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.612522
GSM1303256 DRG RSOx1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.675771
GSM1303257 DRG RSOx2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.686922
GSM1303258 DRG RSOx3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.574759
GSM1303259 DRG RSOx4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.657253
GSM1303260 DRG RSS1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.582429
GSM1303261 DRG RSS2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.620093
GSM1303262 DRG RSS3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.533494
GSM1303263 DRG RSS6 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.514414

ID GSE55573
Title Using DNA microarray to screen intracellular signal pathways of hypoglycemic activity by electroacupuncture of Zusanli (ST36) acupoints in streptozotocin-induced rats with diabetes
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1339443 Mock skeletal muscle strain: Wistar age: 8-10 week-old gender: Male 110.8715
GSM1339444 EA (electroacupuncture) skeletal muscle strain: Wistar age: 8-10 week-old gender: Male 122.7269