Overview of EBOV associated Cell line (Mutation)

ID Literature Title Group
1 18199658 Inhibition of IRF-3 activation by VP35 is critical for the high level of virulence of ebola virus
Mutation
2 20071589 Mutations abrogating VP35 interaction with double-stranded RNA render Ebola virus avirulent in guinea pigs
Mutation
3 23794798 In Vivo Replication and Pathogenesis of Vesicular Stomatitis Virus Recombinant M40 Containing Ebola Virus L-Domain Sequences
Mutation
4 16977667 Structure-function analysis of the soluble glycoprotein, sGP, of Ebola virus
Mutation
5 35384693 TIM-1 Augments Cellular Entry of Ebola Virus Species and Mutants, Which Is Blocked by Recombinant TIM-1 Protein
Mutation
6 24721789 Analysis of determinants in filovirus glycoproteins required for tetherin antagonism
Mutation
7 32098814 Serine-Arginine Protein Kinase 1 Regulates Ebola Virus Transcription
Mutation
8 40186866 Molecular basis for the increased fusion activity of the Ebola virus glycoprotein epidemic variant A82V: Insights from simulations and experiments
Mutation
9 37333330 Ebola Virus NP Binding to Host Protein Phosphatase-1 Regulates Capsid Formation
Mutation
10 33593971 A Glycoprotein Mutation That Emerged during the 2013-2016 Ebola Virus Epidemic Alters Proteolysis and Accelerates Membrane Fusion
Mutation
11 28084671 Functional mutations in spike glycoprotein of Zaire ebolavirus associated with an increase in infection efficiency
Mutation
12 31289183 A Hyperstabilizing Mutation in the Base of the Ebola Virus Glycoprotein Acts at Multiple Steps To Abrogate Viral Entry
Mutation
13 28238624 Biochemical Basis for Increased Activity of Ebola Glycoprotein in the 2013-16 Epidemic
Mutation
14 27814506 Ebola Virus Glycoprotein with Increased Infectivity Dominated the 2013-2016 Epidemic
Mutation
15 22378924 Productive replication of Ebola virus is regulated by the c-Abl1 tyrosine kinase
Mutation
16 18353943 Whole-genome expression profiling reveals that inhibition of host innate immune response pathways by Ebola virus can be reversed by a single amino acid change in the VP35 protein
Mutation
17 37243162 Ebolavirus Species-Specific Interferon Antagonism Mediated by VP24
Mutation
18 31717793 Generation and Characterization of a Mouse-Adapted Makona Variant of Ebola Virus
Mutation
19 16698997 Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling
Mutation
20 19828757 The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide
Mutation
21 25142601 Molecular basis for ebolavirus VP35 suppression of human dendritic cell maturation
Mutation
22 35533195 Ubiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly
Mutation
23 36069549 Enhanced In Vitro and In Vivo Potency of a T Cell Epitope in the Ebola Virus Glycoprotein Following Amino Acid Replacement at HLA-A*02:01 Binding Positions
Mutation
24 40288648 Ebola virus nucleoprotein interaction with host protein phosphatase-1 regulates its dimerization and capsid formation
Mutation
25 10482652 Mutational analysis of the putative fusion domain of Ebola virus glycoprotein
Mutation
26 17475648 Ebola virus glycoprotein 1: identification of residues important for binding and postbinding events
Mutation
27 17065211 The VP35 protein of Ebola virus inhibits the antiviral effect mediated by double-stranded RNA-dependent protein kinase PKR
Mutation
28 15892969 Functional characterization of Ebola virus L-domains using VSV recombinants
Mutation
29 28397835 An inter-residue network model to identify mutational-constrained regions on the Ebola coat glycoprotein
Mutation
30 30206174 Structural Basis of Pan-Ebolavirus Neutralization by a Human Antibody against a Conserved, yet Cryptic Epitope
Mutation
31 33436428 Atypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment Is Associated with Glycoprotein Mutations within the Fusion Loop
Mutation
32 34632543 Identification and Characterization of a Novel Single Domain Antibody Against Ebola Virus
Mutation
33 38603762 Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies
Mutation
34 16683867 Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs
Mutation
35 39726359 To be or not to be phosphorylated: understanding the role of Ebola virus nucleoprotein in the dynamic interplay with the transcriptional activator VP30 and the host phosphatase PP2A-B56
Mutation
36 24495995 In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity
Mutation
37 15650213 VP40 octamers are essential for Ebola virus replication
Mutation
38 23302883 A mutation in the Ebola virus envelope glycoprotein restricts viral entry in a host species- and cell-type-specific manner
Mutation
39 21987742 Kunjin virus replicon-based vaccines expressing Ebola virus glycoprotein GP protect the guinea pig against lethal Ebola virus infection
Mutation
40 33141416 The two-stage interaction of Ebola virus VP40 with nucleoprotein results in a switch from viral RNA synthesis to virion assembly/budding
Mutation
41 20516601 Crystallization and preliminary X-ray analysis of Ebola VP35 interferon inhibitory domain mutant proteins
Mutation
42 22289166 dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35
Mutation
43 32234486 Structure-Based Design of Prefusion-Stabilized Filovirus Glycoprotein Trimers
Mutation
44 29869979 Immunogenicity of propagation-restricted vesicular stomatitis virus encoding Ebola virus glycoprotein in guinea pigs
Mutation
45 31618932 Analysis of Resistance of Ebola Virus Glycoprotein-Driven Entry Against MDL28170, An Inhibitor of Cysteine Cathepsins
Mutation
46 28228590 A Polymorphism within the Internal Fusion Loop of the Ebola Virus Glycoprotein Modulates Host Cell Entry
Mutation
47 28539437 Spontaneous Mutation at Amino Acid 544 of the Ebola Virus Glycoprotein Potentiates Virus Entry and Selection in Tissue Culture
Mutation
48 30333174 Naturally Occurring Single Mutations in Ebola Virus Observably Impact Infectivity
Mutation
49 31952352 Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111
Mutation
50 33028676 Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases
Mutation
51 24696482 Ebolavirus entry requires a compact hydrophobic fist at the tip of the fusion loop
Mutation
52 26092855 Shedding of Ebola Virus Surface Glycoprotein Is a Mechanism of Self-regulation of Cellular Cytotoxicity and Has a Direct Effect on Virus Infectivity
Mutation
53 30524754 Ebola virus, but not Marburg virus, replicates efficiently and without required adaptation in snake cells
Mutation
54 21249196 Measuring the strength of interaction between the Ebola fusion peptide and lipid rafts: implications for membrane fusion and virus infection
Mutation
55 33462517 Ebola virus glycoprotein interacts with cholesterol to enhance membrane fusion and cell entry
Mutation
56 29507309 Recombinant RNA-Dependent RNA Polymerase Complex of Ebola Virus
Mutation
57 25972536 Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells
Mutation
58 31694758 Ebola virus replication is regulated by the phosphorylation of viral protein VP35
Mutation
59 25330123 A loop region in the N-terminal domain of Ebola virus VP40 is important in viral assembly, budding, and egress
Mutation
60 27328459 Interdomain salt-bridges in the Ebola virus protein VP40 and their role in domain association and plasma membrane localization
Mutation
61 32455873 A Conserved Tryptophan in the Ebola Virus Matrix Protein C-Terminal Domain Is Required for Efficient Virus-Like Particle Formation
Mutation
62 34372582 Cysteine Mutations in the Ebolavirus Matrix Protein VP40 Promote Phosphatidylserine Binding by Increasing the Flexibility of a Lipid-Binding Loop
Mutation
Contents
Description
Disease Group Note
  • The label in Group indicates that the disease is mentioned in mutation or integration research. Click the eye label to view the corresponding module information.