Virus Info Summary

The Virus module provides an interface of each virus with a summary and links to ViMIC 2.0 features to help users easy to query research questions on VMs, VISs-Factors overlap or target genes.


Virus Name Size Classification Brief Description View
 Hepatitis B Virus  (HBV) 
M
I
3.2kb Artverviricota
Blubervirales
Hepadnaviridae
Orthohepadnavirus
Hepatitis B virus
HBV is a partially double-stranded DNA virus that primarily infects hepatocytes. It causes acute and chronic hepatitis, with chronic infection leading to severe complications like cirrhosis and liver cancer. Transmission occurs via blood and bodily fluids. The virus replicates via reverse transcription and integrates into host DNA. Detail
 Human Papillomavirus  (HPV) 
M
I
8kb Papillomaviricota
Sepolyvirales
Papillomaviridae
Alphapapillomavirus
Human papillomavirus
HPV is a small double-stranded circular DNA virus with a genome of approximately 8000 base pairs. The HPV life cycle strictly follows the differentiation program of the host keratinocyte. It is thought that the HPV virion infects epithelial tissues through micro-abrasions, whereby the virion associates with putative receptors such as alpha integrins, laminins, and annexin A2 leading to the entry of the virions into basal epithelial cells through clathrin-mediated endocytosis and/or caveolin-mediated endocytosis depending on the type of HPV. Detail
 Epstein-Barr Virus  (EBV) 
M
I
172kb Peploviricota
Herpesvirales
Orthoherpesviridae
Lymphocryptovirus
Human gammaherpesvirus 4
EBV is one of the nine known human herpesvirus types in the herpes family, and is one of the most common viruses in humans. EBV is a double-stranded DNA virus and is the first identified oncogenic virus, or a virus that can cause cancer. Detail
 Merkel Cell Polyomavirus  (MCV) 
M
I
5.4kb Shotokuvirae
Sepolyvirales
Polyomaviridae
Alphapolyomavirus
Merkel cell polyomavirus
MCV was first described in January 2008 in Pittsburgh, Pennsylvania. It was the first example of a human viral pathogen discovered using unbiased metagenomic next-generation sequencing with a technique called digital transcriptome subtraction. MCV is one of seven currently known human oncoviruses. It is suspected to cause the majority of cases of Merkel cell carcinoma, a rare but aggressive form of skin cancer. Detail
 Human Immunodeficiency Virus  (HIV) 
M
I
9.8kb Artverviricota
Ortervirales
Retroviridae
Lentivirus
Human immunodeficiency virus 1/2
HIV are two species of Lentivirus (a subgroup of retrovirus) that infect humans.Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Detail
 Human T-lymphotropic Virus 1  (HTLV1) 
M
I
9kb Artverviricota
Ortervirales
Retroviridae
Deltaretrovirus
Primate T-lymphotropic virus 1
HTLV1 is a retrovirus of the human T-lymphotropic virus (HTLV) family. The most well characterized are adult T-cell lymphoma (ATL) and HTLV-I-associated myelopathy/Tropical spastic paraparesis (HAM/TSP), both of which are only diagnosed in individuals testing positive to HTLV-1 infection. Detail
 Xenotropic Murine Leukemia Virus-Related Virus  (XMRV) 
M
I
8.3kb Artverviricota
Ortervirales
Retroviridae
Gammaretrovirus
Xenotropic murine leukemia virus-related virus
XMRV is a gammaretrovirus linked to prostate carcinoma and chronic fatigue syndrome. Detail
 Influenza Virus  (IV) 
M
A:13.5kb
B:14.6kb
C:12.9kb
D:12.9-13.3kb
Negarnaviricota
Articulavirales
Orthomyxoviridae
Alphainfluenzavirus Betainfluenzavirus Gammainfluenzavirus Deltainfluenzavirus
Alphainfluenzavirus Betainfluenzavirus Gammainfluenzavirus Deltainfluenzavirus
IV virion is pleomorphic; the viral envelope can occur in spherical and filamentous forms. There are four genera of influenza virus, each containing only a single species, or type. Influenza A and C infect a variety of species (including humans), while influenza B almost exclusively infects humans, and influenza D infects cattle and pigs. Detail
 Severe Acute Respiratory Syndrome Coronavirus 2  (SARS-CoV-2) 
M
30kb Pisuviricota
Nidovirales
Coronaviridae
Betacoronavirus
Betacoronavirus pandemicum
SARS-CoV-2 is a strain of coronavirus that causes COVID-19, the respiratory illness responsible for the COVID-19 pandemic. Detail
 Herpes Simplex Virus 1  (HSV1) 
M
152kb Peploviricota
Herpesvirales
Orthoherpesviridae
Simplexvirus
Simplexvirus humanalpha1
HSV1 infects humans, most often as cold sores. It is very common and contagious; about 67% of the world population under the age of 50 has Herpes simplex virus 1. Detail
 Herpes Simplex Virus 2  (HSV2) 
M
155kb Peploviricota
Herpesvirales
Orthoherpesviridae
Simplexvirus
Simplexvirus humanalpha2
HSV2 most often as genital herpes. In the United States more than one in six people have the virus. It is primarily a sexually transmitted infection. Herpes simplex virus 2 tends to reside in the sacral ganglia. Herpes simplex virus 2 is periodically shed in the human genital tract, most often asymptomatically. Detail
 Human Cytomegalovirus  (HCMV) 
M
236kb Peploviricota
Herpesvirales
Orthoherpesviridae
Cytomegalovirus
Human betaherpesvirus 5
HCMV also called human herpesvirus 5 (HHV-5), is a species of virus in the genus Cytomegalovirus, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is also commonly called CMV. CMV is a double-stranded DNA virus. Detail
 Kaposi's Sarcoma-Associated Herpesvirus  (KSHV) 
M
165kb Peploviricota
Herpesvirales
Orthoherpesviridae
Rhadinovirus
Rhadinovirus humangamma8
KSHV is the ninth known human herpesvirus. It is also called Human herpesvirus 8, or HHV-8 in short. This virus causes Kaposi's sarcoma, a cancer commonly occurring in AIDS patients, as well as primary effusion lymphoma, HHV-8-associated multicentric Castleman's disease and KSHV inflammatory cytokine syndrome. Detail
 Varicella-Zoster Virus  (VZV) 
M
125kb Peploviricota
Herpesvirales
Orthoherpesviridae
Varicellovirus
Varicellovirus humanalpha3
VZV also known as human herpesvirus 3 (HHV-3, HHV3), is one of nine known herpes viruses that can infect humans. It causes chickenpox (varicella) commonly affecting children and young adults, and shingles (herpes zoster) in adults but rarely in children. Detail
 Hepatitis A Virus  (HAV) 
M
7.5kb Pisuviricota
Picornavirales
Picornaviridae
Hepatovirus
Hepatovirus ahepa
HAV causes Hepatitis A; it is a type of viral hepatitis. Many cases have few or no symptoms, especially in the young. The time between infection and symptoms, in those who develop them, is two to six weeks. When symptoms occur, they typically last eight weeks and may include nausea, vomiting, diarrhea, jaundice, fever, and abdominal pain. Detail
 Hepatitis C Virus  (HCV) 
M
9.6kb Kitrinoviricota
Amarillovirales
Flaviviridae
Hepacivirus
Hepacivirus hominis
HCV is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. The hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer (hepatocellular carcinoma, abbreviated HCC) and lymphomas in humans. Detail
 Hepatitis D Virus  (HDV) 
M
1.7kb Riboviria
Bunyavirales
Kolmioviridae
Deltavirus
Hepatitis delta virus
HDV is a type of viral hepatitis caused by the hepatitis delta virus (HDV). HDV is one of five known hepatitis viruses: A, B, C, D, and E. HDV is considered to be a satellite (a type of subviral agent) because it can propagate only in the presence of the hepatitis B virus (HBV). Detail
 Hepatitis E Virus  (HEV) 
M
7.2kb Kitrinoviricota
Hepelivirales
Hepeviridae
Paslahepevirus
Paslahepevirus balayani
HEV is the causative agent of hepatitis E. Globally, approximately 939 million corresponding to 1 in 8 individuals have ever experienced HEV infection. About 15–110 million individuals have recent or ongoing HEV infection. The virus particle was first seen in 1983, but was only molecularly cloned in 1989. Detail
 Dengue Virus  (DENV) 
M
11kb Kitrinoviricota
Amarillovirales
Flaviviridae
Flavivirus
Orthoflavivirus denguei
DENV Dengue virus (DENV) is the cause of dengue fever. It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, all of which can cause the full spectrum of disease. Detail
 Yellow Fever Virus  (YFV) 
M
11kb Kitrinoviricota
Amarillovirales
Flaviviridae
Flavivirus
Yellow fever virus
YFV is a viral disease of typically short duration. In most cases, symptoms include fever, chills, loss of appetite, nausea, muscle pains-particularly in the back and headaches. Detail
 Japanese Encephalitis Virus  (JEV) 
M
11kb Kitrinoviricota
Amarillovirales
Flaviviridae
Flavivirus
Orthoflavivirus japonicum
JEV is a virus from the family Flaviviridae, part of the Japanese encephalitis serocomplex of nine genetically and antigenically related viruses, some of which are particularly severe in horses, and four of which, including West Nile virus, are known to infect humans. JEV is generally spread by mosquitoes, specifically those of the Culex type. Detail
 Tick-Borne Encephalitis Virus  (TBEV) 
M
11kb Kitrinoviricota
Amarillovirales
Flaviviridae
Flavivirus
Orthoflavivirus encephalitidis
TBEV is a positive-strand RNA virus associated with tick-borne encephalitis in the genus Flavivirus. Detail
 Crimean-Congo Hemorrhagic Fever Virus  (CCHFV) 
M
19-20kb Negarnaviricota
Hareavirales
Nairoviridae
Orthonairovirus
Orthonairovirus haemorrhagiae
CCHFV is a viral disease. Symptoms of CCHF may include fever, muscle pains, headache, vomiting due to loss of net saline of basal cells, diarrhea, and bleeding into the skin. Onset of symptoms is less than two weeks following exposure. Complications may include liver failure. Detail
 Chikungunya Virus  (CHIKV) 
M
12kb Kitrinoviricota
Martellivirales
Togaviridae
Alphavirus
Alphavirus chikungunya
CHIKV is a member of the genus Alphavirus, and family Togaviridae. Chikungunya virus features an icosahedral capsid surrounded by a lipid envelope, with a diameter ranging from 60 to 70 nm. It was first isolated in 1953 in Tanzania and is an RNA virus with a positive-sense single-stranded genome of about 11.6kb. It is a member of the Semliki Forest virus complex and is closely related to Ross River virus, O'nyong'nyong virus, and Semliki Forest virus. Detail
 Zika Virus  (ZIKV) 
M
11kb Kitrinoviricota
Amarillovirales
Flaviviridae
Flavivirus
Zika virus
ZIKV is a member of the virus family Flaviviridae. It is spread by daytime-active Aedes mosquitoes, such as A. aegypti and A. albopictus. Zika virus shares a genus with the dengue, yellow fever, Japanese encephalitis, and West Nile viruses. Detail
 Ebola Virus  (EBOV) 
M
19kb Negarnaviricota
Mononegavirales
Filoviridae
Ebolavirus
Zaire ebolavirus
EBOV also known as Ebola virus disease (EVD) and Ebola hemorrhagic fever (EHF), is a viral hemorrhagic fever in humans and other primates, caused by ebolaviruses. Symptoms typically start anywhere between two days and three weeks after infection. The first symptoms are usually fever, sore throat, muscle pain, and headaches. These are usually followed by vomiting, diarrhoea, rash and decreased liver and kidney function, at which point some people begin to bleed both internally and externally. Detail
 Marburg Virus  (MARV) 
M
19kb Negarnaviricota
Mononegavirales
Filoviridae
Marburgvirus
Marburg marburgvirus
MARV is a hemorrhagic fever virus of the Filoviridae family of viruses and a member of the species Marburg marburgvirus, genus Marburgvirus. It causes Marburg virus disease in primates, a form of viral hemorrhagic fever. Detail
 Rabies Virus  (RABV) 
M
12kb Negarnaviricota
Mononegavirales
Rhabdoviridae
Lyssavirus
Rabies lyssavirus
RABV is a neurotropic virus that causes rabies in animals, including humans. It can cause violence, hydrophobia, and fever. Detail
Contents
Description
Click the Detail button to show a virus summary and the information of mutations, and target genes in each virus. VIS-Cistrome factor overlapped records are only provided by viruses that can integrate into the host genome.