Overview of VZV Mutation, Integration-Cistrome Factor Overlap and Target gene

Varicella-Zoster Virus (VZV) also known as human herpesvirus 3 (HHV-3, HHV3), is one of nine known herpes viruses that can infect humans. It causes chickenpox (varicella) commonly affecting children and young adults, and shingles (herpes zoster) in adults but rarely in children.
Size: 125kb
Encoding: gB, gC, gE, gH, gI, gM, IE62, ORF0, ORF62, Pol, TK, etc.
Human Disease: Herpes zoster, Chickenpox, etc.
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VZV Mutation Info
Only show 100 info Click here to see all VZV Mutation Sites
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 10440813 R665G
Pol
ORF28
Chickenpox
D
View
2 10440813 V666L
Pol
ORF28
Chickenpox
D
View
3 10440813 Q692R
Pol
ORF28
Chickenpox
D
View
4 10440813 R806S
Pol
ORF28
Chickenpox
D
View
5 10440813 L809S
Pol
ORF28
Chickenpox
D
View
6 9882337 S343A
gI
ORF67
Chickenpox
T
View
7 9882337 T322A
gI
ORF67
Chickenpox
View
8 12498673 D150N
gE
ORF68
Herpes zoster
R
S
I
C
L
View
9 12498673 G448A
gE
ORF68
Herpes zoster
R
S
I
C
L
View
10 30628536 A473A
ORF62
ORF62
Herpes zoster
R
C
L
View
11 30628536 A657T
ORF62
ORF62
Herpes zoster
R
C
L
View
12 30628536 A666A
ORF62
ORF62
Herpes zoster
R
C
L
View
13 30628536 L446P
ORF62
ORF62
Herpes zoster
R
C
L
View
14 30628536 P341P
ORF62
ORF62
Herpes zoster
R
C
L
View
15 30628536 Q661Q
ORF62
ORF62
Herpes zoster
R
C
L
View
16 30628536 R373R
ORF62
ORF62
Herpes zoster
R
C
L
View
17 30628536 R609R
ORF62
ORF62
Herpes zoster
R
C
L
View
18 30628536 R958G
ORF62
ORF62
Herpes zoster
R
C
L
View
19 30628536 S628G
ORF62
ORF62
Herpes zoster
R
C
L
View
20 30628536 T509T
ORF62
ORF62
Herpes zoster
R
C
L
View
21 30628536 V512V
ORF62
ORF62
Herpes zoster
R
C
L
View
22 30628536 V516V
ORF62
ORF62
Herpes zoster
R
C
L
View
23 30628536 V703A
ORF62
ORF62
Herpes zoster
R
C
L
View
24 30628536 T106262C
ORF62
ORF62
Herpes zoster
R
C
L
View
25 30628536 A107026G
ORF62
ORF62
Herpes zoster
R
C
L
View
26 30628536 T107136C
ORF62
ORF62
Herpes zoster
R
C
L
View
27 30628536 C107151T
ORF62
ORF62
Herpes zoster
R
C
L
View
28 30628536 C107165T
ORF62
ORF62
Herpes zoster
R
C
L
View
29 30628536 T107252C
ORF62
ORF62
Herpes zoster
R
C
L
View
30 30628536 T107307C
ORF62
ORF62
Herpes zoster
R
C
L
View
31 30628536 C107586T
ORF62
ORF62
Herpes zoster
R
C
L
View
32 30628536 A107599R
ORF62
ORF62
Herpes zoster
R
C
L
View
33 30628536 C107607A
ORF62
ORF62
Herpes zoster
R
C
L
View
34 30628536 T107715C
ORF62
ORF62
Herpes zoster
R
C
L
View
35 30628536 A107797G
ORF62
ORF62
Herpes zoster
R
C
L
View
36 30628536 C108015T
ORF62
ORF62
Herpes zoster
R
C
L
View
37 30628536 T108111C
ORF62
ORF62
Herpes zoster
R
C
L
View
38 25712361 T237K
Pol
ORF28
Herpes zoster
Encephalitis
R
View
39 25712361 A955T
Pol
ORF28
Herpes zoster
Encephalitis
D
R
View
40 25712361 N334X
TK
ORF36
Herpes zoster
Encephalitis
D
R
View
41 25712361 A163X
TK
ORF36
Herpes zoster
Encephalitis
D
R
View
42 25712361 Q303X
TK
ORF36
Herpes zoster
Encephalitis
D
R
View
43 25712361 L73I
TK
ORF36
Herpes zoster
Encephalitis
R
View
44 25712361 W225R
TK
ORF36
Herpes zoster
Encephalitis
D
R
View
45 25712361 T256M
TK
ORF36
Herpes zoster
Encephalitis
D
R
View
46 25712361 7_74del
TK
ORF36
Herpes zoster
Encephalitis
Cell line
D
R
View
47 36468883 R699Q
gB
ORF31
Varicella Zoster Virus Infection
View
48 17069870 S628G
IE62
Varicella Zoster Virus Infection
L
View
49 17069870 R958G
IE62
Varicella Zoster Virus Infection
L
View
50 17069870 I1260V
IE62
Varicella Zoster Virus Infection
L
View
51 11602787 N779S
Pol
ORF28
Varicella Zoster Virus Infection
D
S
View
52 11602787 G805C
Pol
ORF28
Varicella Zoster Virus Infection
D
S
View
53 11602787 V855M
Pol
ORF28
Varicella Zoster Virus Infection
D
S
View
54 21345964 C95A
gI
ORF67
Varicella Zoster Virus Infection
Cell line
R
View
55 21345964 C83A
gI
ORF67
Varicella Zoster Virus Infection
Cell line
R
View
56 21345964 C106A
gI
ORF67
Varicella Zoster Virus Infection
Cell line
R
View
57 21345964 N116A
gI
ORF67
Varicella Zoster Virus Infection
Cell line
R
View
58 21345964 C200A
gI
ORF67
Varicella Zoster Virus Infection
Cell line
R
View
59 16971426 G102A
ORF66
ORF66
Varicella Zoster Virus Infection
Cell line
View
60 16971426 S250P
ORF66
ORF66
Varicella Zoster Virus Infection
Cell line
View
61 16971426 P251S
ORF66
ORF66
Varicella Zoster Virus Infection
Cell line
View
62 16971426 D224N
ORF66
ORF66
Varicella Zoster Virus Infection
Cell line
View
63 16971426 E210D
ORF66
ORF66
Varicella Zoster Virus Infection
Cell line
View
64 16971426 K122R
ORF66
ORF66
Varicella Zoster Virus Infection
Cell line
View
65 16971426 D206N
ORF66
ORF66
Varicella Zoster Virus Infection
Cell line
View
66 10508017 E48G
TK
ORF36
Acquired Immunodeficiency Syndrome
D
R
S
View
67 10508017 A143G
TK
ORF36
Acquired Immunodeficiency Syndrome
D
R
S
View
68 10508017 S179N
TK
ORF36
Acquired Immunodeficiency Syndrome
R
S
View
69 10508017 V172C
TK
ORF36
Acquired Immunodeficiency Syndrome
R
S
View
70 10508017 S179I
TK
ORF36
Acquired Immunodeficiency Syndrome
R
S
View
71 9852975 E512K
Pol
ORF28
Acquired Immunodeficiency Syndrome
D
R
C
View
72 9852975 S863G
Pol
ORF28
Acquired Immunodeficiency Syndrome
R
C
View
73 9624615 C907T
TK
ORF36
Acquired Immunodeficiency Syndrome
Herpes zoster
D
C
View
74 9624615 Q303X
TK
ORF36
Acquired Immunodeficiency Syndrome
Herpes zoster
D
C
View
75 21539861 E824Q
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
76 21539861 R984H
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
77 21539861 M286I
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
78 21539861 H1089Y
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
79 28886462 R753K
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
80 28886462 V777I
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
81 28886462 D645Y
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
82 28886462 T39A
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
83 28886462 M201I
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
84 28886462 G218D
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
85 28886462 S386A
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
86 28886462 Q402P
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
87 28886462 T417I
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
88 28886462 G723R
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
89 28886462 R950C
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
90 28886462 T1066S
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
91 28886462 R1076C
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
92 28886462 C1185Y
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
93 28886462 G186C
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
94 28886462 S863G
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
95 28886462 C1159R
Pol
ORF28
Chickenpox
Herpes zoster
G
R
C
View
96 28886462 S51L
TK
ORF36
Chickenpox
Herpes zoster
G
R
C
View
97 28886462 K186R
TK
ORF36
Chickenpox
Herpes zoster
G
R
C
View
98 28886462 N119D
TK
ORF36
Chickenpox
Herpes zoster
G
R
C
View
99 28886462 V194A
TK
ORF36
Chickenpox
Herpes zoster
G
R
C
View
100 21539861 T237K
Pol
ORF28
Chickenpox
Herpes zoster
R
C
View
Contents
Description

The table shows all curated mutation sites of VZV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.


VZV Target Gene Info
Only show 100 info Click here to see all VZV Target Gene
ID Target gene Virus Impact Literature Count Description Detail
1 ARL4D VZV
M
1
E
View
2 CD4 VZV
M
1
E
View
3 CD8A VZV
M
1
E
View
4 CDK1 VZV
M
1
E
View
5 GEM VZV
M
1
E
View
6 IFNG VZV
M
1
E
View
7 KRT15 VZV
M
1
E
View
8 RASD1 VZV
M
1
E
View
9 RASL11B VZV
M
1
E
View
10 RHOV VZV
M
1
E
View
11 RND1 VZV
M
1
E
View
12 RRAD VZV
M
1
E
View
Contents Description and
Data Download
Table Note
I
Target gene is affected by virus integration.
M
Target gene is associated with the virus gene/protein/region.
E
Target gene is detected in the expression profiling data.
S
Target gene is detected in the single-cell transcriptome data.
C
Target gene is detected in the genome binding/occupancy profiling data.
M
Target gene is detected in the methylation profiling data.
F
Target gene provides figures to visualize the analysis results.
F indicates that this gene has visualization results on at least one type of sequencing data.